GB1006880A - Substituted chromonamine complexes - Google Patents
Substituted chromonamine complexesInfo
- Publication number
- GB1006880A GB1006880A GB25676/62A GB2567662A GB1006880A GB 1006880 A GB1006880 A GB 1006880A GB 25676/62 A GB25676/62 A GB 25676/62A GB 2567662 A GB2567662 A GB 2567662A GB 1006880 A GB1006880 A GB 1006880A
- Authority
- GB
- United Kingdom
- Prior art keywords
- cerous
- chromonamine
- hydrogen
- carbon atoms
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 abstract 2
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 150000004820 halides Chemical class 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical group C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 1
- 239000000443 aerosol Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 229910000175 cerite Inorganic materials 0.000 abstract 1
- DRVWBEJJZZTIGJ-UHFFFAOYSA-N cerium(3+);oxygen(2-) Chemical compound [O-2].[O-2].[O-2].[Ce+3].[Ce+3] DRVWBEJJZZTIGJ-UHFFFAOYSA-N 0.000 abstract 1
- GHLITDDQOMIBFS-UHFFFAOYSA-H cerium(3+);tricarbonate Chemical compound [Ce+3].[Ce+3].[O-]C([O-])=O.[O-]C([O-])=O.[O-]C([O-])=O GHLITDDQOMIBFS-UHFFFAOYSA-H 0.000 abstract 1
- 229910000421 cerium(III) oxide Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 210000001519 tissue Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
- C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
- C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
- C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention comprises complexes of formula <FORM:1006880/C2/1> wherein Hal is a halogen atom, R is hydrogen or an alkyl or hydroxyalkyl group having 1 to 4 carbon atoms or the groups R, in combination with the nitrogen atom to which they are attached, form a piperidine, morpholine or pyrrolidine ring, R1 is hydrogen or an alkyl group having 1 to 3 carbon atoms, R2 is an alkyl group having 1 to 3 carbon atoms, an aryl group or an alkoxy-substituted aryl group, R3 is hydrogen or a hydroxy or alkoxy group, n is 1, 2 or 3, and X is oxygen or a direct link, and their preparation by reaction of a cerous halide with the appropriate chromonamine hydrohalide or with the appropriate chromonamine in the presence of a hydrohalic acid. The cerous halide used may be prepared in situ by dissolving cerous carbonate, cerous oxide or a cerite ore in a hydrohalic acid. The compounds of the invention may be used to increase the oxygen supply to tissues, organs or blood, and may for example be inhaled as aerosols.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEV20913A DE1227473B (en) | 1961-07-04 | 1961-07-04 | Process for the preparation of cerium (III) -flavone-amino complex compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1006880A true GB1006880A (en) | 1965-10-06 |
Family
ID=7578826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB25676/62A Expired GB1006880A (en) | 1961-07-04 | 1962-07-04 | Substituted chromonamine complexes |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE617971A (en) |
| CH (1) | CH444881A (en) |
| DE (1) | DE1227473B (en) |
| FR (1) | FR2207M (en) |
| GB (1) | GB1006880A (en) |
-
1961
- 1961-07-04 DE DEV20913A patent/DE1227473B/en active Pending
-
1962
- 1962-05-22 BE BE617971A patent/BE617971A/en unknown
- 1962-06-05 FR FR899682A patent/FR2207M/en not_active Expired
- 1962-06-18 CH CH730262A patent/CH444881A/en unknown
- 1962-07-04 GB GB25676/62A patent/GB1006880A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE1227473B (en) | 1966-10-27 |
| FR2207M (en) | 1963-12-16 |
| CH444881A (en) | 1967-10-15 |
| BE617971A (en) | 1962-09-17 |
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