GB1003748A - Diagnostic compositions for the determination of blood coagulant factor levels - Google Patents
Diagnostic compositions for the determination of blood coagulant factor levelsInfo
- Publication number
- GB1003748A GB1003748A GB4282062A GB4282062A GB1003748A GB 1003748 A GB1003748 A GB 1003748A GB 4282062 A GB4282062 A GB 4282062A GB 4282062 A GB4282062 A GB 4282062A GB 1003748 A GB1003748 A GB 1003748A
- Authority
- GB
- United Kingdom
- Prior art keywords
- bovine plasma
- composition
- calcium
- determination
- fibrinogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 239000000701 coagulant Substances 0.000 title 1
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 abstract 4
- 241000283690 Bos taurus Species 0.000 abstract 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 abstract 4
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 2
- 206010053567 Coagulopathies Diseases 0.000 abstract 2
- 108010014172 Factor V Proteins 0.000 abstract 2
- 108010049003 Fibrinogen Proteins 0.000 abstract 2
- 102000008946 Fibrinogen Human genes 0.000 abstract 2
- 108010000499 Thromboplastin Proteins 0.000 abstract 2
- 102000002262 Thromboplastin Human genes 0.000 abstract 2
- TZCXTZWJZNENPQ-UHFFFAOYSA-L barium sulfate Chemical compound [Ba+2].[O-]S([O-])(=O)=O TZCXTZWJZNENPQ-UHFFFAOYSA-L 0.000 abstract 2
- 210000005013 brain tissue Anatomy 0.000 abstract 2
- 239000001110 calcium chloride Substances 0.000 abstract 2
- 229910001628 calcium chloride Inorganic materials 0.000 abstract 2
- 230000035602 clotting Effects 0.000 abstract 2
- 239000012153 distilled water Substances 0.000 abstract 2
- 229940012952 fibrinogen Drugs 0.000 abstract 2
- 239000011780 sodium chloride Substances 0.000 abstract 2
- 230000000087 stabilizing effect Effects 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- CFWRDBDJAOHXSH-SECBINFHSA-N 2-azaniumylethyl [(2r)-2,3-diacetyloxypropyl] phosphate Chemical compound CC(=O)OC[C@@H](OC(C)=O)COP(O)(=O)OCCN CFWRDBDJAOHXSH-SECBINFHSA-N 0.000 abstract 1
- 108010039209 Blood Coagulation Factors Proteins 0.000 abstract 1
- 102000015081 Blood Coagulation Factors Human genes 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 239000003114 blood coagulation factor Substances 0.000 abstract 1
- 229940019700 blood coagulation factors Drugs 0.000 abstract 1
- 229910052791 calcium Inorganic materials 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910001424 calcium ion Inorganic materials 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
A lyophilized diagnostic composition for use in determining blood coagulaton factors consists essentially of tissue thromboplastin having a clotting time of about 30 seconds, calcium ion, bovine plasma containing stabilizing concentrations of Factor V and fibrinogen, said composition being characterized by freedom from cephalia and having a pH range of 7,2-7,6. In one example, barium sulphate adsorbed oxolated bovine plasma is added to distilled water containing sodium chloride, calcium chloride and acetone treated horse brain tissue, buffered at pH 7,2-7,6. Specification 917,012 is referred to.ALSO:A lyophilized diagnostic composition for use in determining blood coagulation factors consists essentially of tissue thromboplastin having a clotting time of about 30 seconds, calcium in, bovine plasma containing stabilizing concentrations of Factor V and fibrinogen, said composition being characterised by freedom from cephalin and having a pH range of 7.2 to 7.6. In one example, barium-sulphate-adsorbed oxalated bovine plasma is added to distilled water containing sodium chloride, calcium chloride and acetone-treated horse brain tissue, buffered at 7.2 to 7.6. Specification 917,012 is referred to.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4282062A GB1003748A (en) | 1962-11-13 | 1962-11-13 | Diagnostic compositions for the determination of blood coagulant factor levels |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4282062A GB1003748A (en) | 1962-11-13 | 1962-11-13 | Diagnostic compositions for the determination of blood coagulant factor levels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1003748A true GB1003748A (en) | 1965-09-08 |
Family
ID=10426116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4282062A Expired GB1003748A (en) | 1962-11-13 | 1962-11-13 | Diagnostic compositions for the determination of blood coagulant factor levels |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1003748A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11604026B2 (en) | 2019-03-14 | 2023-03-14 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
| US11634257B2 (en) | 2017-10-09 | 2023-04-25 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
-
1962
- 1962-11-13 GB GB4282062A patent/GB1003748A/en not_active Expired
Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11634257B2 (en) | 2017-10-09 | 2023-04-25 | Terumo Bct Biotechnologies, Llc | Lyophilization container and method of using same |
| US11604026B2 (en) | 2019-03-14 | 2023-03-14 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
| US11609042B2 (en) | 2019-03-14 | 2023-03-21 | Terumo Bct Biotechnologies, Llc | Multi-part lyophilization container and method of use |
| US11609043B2 (en) | 2019-03-14 | 2023-03-21 | Terumo Bct Biotechnologies, Llc | Lyophilization container fill fixture, system and method of use |
| US11740019B2 (en) | 2019-03-14 | 2023-08-29 | Terumo Bct Biotechnologies, Llc | Lyophilization loading tray assembly and system |
| US11747082B2 (en) | 2019-03-14 | 2023-09-05 | Terumo Bct Biotechnologies, Llc | Multi-part lyophilization container and method of use |
| US11815311B2 (en) | 2019-03-14 | 2023-11-14 | Terumo Bct Biotechnologies, Llc | Lyophilization container fill fixture, system and method of use |
| US11994343B2 (en) | 2019-03-14 | 2024-05-28 | Terumo Bct Biotechnologies, Llc | Multi-part lyophilization container and method of use |
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