GB1087222A - 12-nitronaphthindolizinediones and processes for their manufacture - Google Patents
12-nitronaphthindolizinediones and processes for their manufactureInfo
- Publication number
- GB1087222A GB1087222A GB23604/66A GB2360466A GB1087222A GB 1087222 A GB1087222 A GB 1087222A GB 23604/66 A GB23604/66 A GB 23604/66A GB 2360466 A GB2360466 A GB 2360466A GB 1087222 A GB1087222 A GB 1087222A
- Authority
- GB
- United Kingdom
- Prior art keywords
- nitronaphthindolizinediones
- manufacture
- processes
- naphthindolizinedione
- acetylnaphthindolizinedione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- ZUHMWOUJSIGOEH-UHFFFAOYSA-N 5-nitronaphtho[1,2-g]indolizine-6,7-dione Chemical class [N+](=O)([O-])C1=CC2=C(C=CN3C=CC=C23)C=2C=CC(C(C12)=O)=O ZUHMWOUJSIGOEH-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- SCRBVDMHSCYROW-UHFFFAOYSA-N 5-acetylnaphtho[1,2-g]indolizine-6,7-dione Chemical compound C(C)(=O)C1=CC2=C(C=CN3C=CC=C23)C=2C=CC(C(C12)=O)=O SCRBVDMHSCYROW-UHFFFAOYSA-N 0.000 abstract 1
- GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 abstract 1
- 229910017604 nitric acid Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Coloring (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
The invention comprises 12-nitronaphthindolizinediones of the formula <FORM:1087222/C2/1> wherein Y is H or one CH3 group. They may be obtained by reacting the corresponding naphthindolizinedione or the corresponding 12-acetylnaphthindolizinedione with concentrated HNO3, preferably at between 0 DEG and 50 DEG C.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB10520/63A GB1087221A (en) | 1963-03-16 | 1963-03-16 | 12-aminonaphthindolizinediones and processes for their manufacture |
| GB12287/64A GB1090633A (en) | 1963-03-16 | 1964-03-24 | Aminobenzonaphthindolizinediones |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1087222A true GB1087222A (en) | 1967-10-18 |
Family
ID=26247575
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB10520/63A Expired GB1087221A (en) | 1963-03-16 | 1963-03-16 | 12-aminonaphthindolizinediones and processes for their manufacture |
| GB23604/66A Expired GB1087222A (en) | 1963-03-16 | 1963-03-16 | 12-nitronaphthindolizinediones and processes for their manufacture |
| GB13701/66A Expired GB1090635A (en) | 1963-03-16 | 1964-03-24 | Benzonaphthindolizinediones |
| GB12287/64A Expired GB1090633A (en) | 1963-03-16 | 1964-03-24 | Aminobenzonaphthindolizinediones |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB10520/63A Expired GB1087221A (en) | 1963-03-16 | 1963-03-16 | 12-aminonaphthindolizinediones and processes for their manufacture |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB13701/66A Expired GB1090635A (en) | 1963-03-16 | 1964-03-24 | Benzonaphthindolizinediones |
| GB12287/64A Expired GB1090633A (en) | 1963-03-16 | 1964-03-24 | Aminobenzonaphthindolizinediones |
Country Status (3)
| Country | Link |
|---|---|
| US (1) | US3336317A (en) |
| CH (1) | CH426836A (en) |
| GB (4) | GB1087221A (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1459137A (en) * | 1973-05-30 | 1976-12-22 | Sandoz Ltd | Naphthoquinone derivatives |
| NO163330C (en) * | 1984-05-03 | 1990-05-09 | Glaxo Group Ltd | ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE ISOQINOLINE DERIVATIVES. |
| NO872963L (en) * | 1986-07-29 | 1988-02-01 | Glaxo Group Ltd | Isoquinoline derivatives. |
| DK616087A (en) * | 1986-11-27 | 1988-05-28 | Glaxo Group Ltd | ISOQUINOLINE DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM |
| GB8800312D0 (en) * | 1988-01-07 | 1988-02-10 | Glaxo Group Ltd | Process |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2850503A (en) * | 1958-09-02 | Preparation of methyl and ethyl n- | ||
| US2439120A (en) * | 1946-10-26 | 1948-04-06 | Eastman Kodak Co | 1-nitro-3-alkylanthrapyridone compounds and process for their preparation |
| US3121086A (en) * | 1961-05-29 | 1964-02-11 | Du Pont | Naphthofuroquinolinediones and naphthofuroisoquinolinediones |
-
1963
- 1963-03-16 GB GB10520/63A patent/GB1087221A/en not_active Expired
- 1963-03-16 GB GB23604/66A patent/GB1087222A/en not_active Expired
-
1964
- 1964-03-06 CH CH288764A patent/CH426836A/en unknown
- 1964-03-24 GB GB13701/66A patent/GB1090635A/en not_active Expired
- 1964-03-24 GB GB12287/64A patent/GB1090633A/en not_active Expired
-
1965
- 1965-03-23 US US442190A patent/US3336317A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| GB1090633A (en) | 1967-11-15 |
| US3336317A (en) | 1967-08-15 |
| GB1090635A (en) | 1967-11-15 |
| GB1087221A (en) | 1967-10-18 |
| CH426836A (en) | 1966-12-31 |
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