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GB1078939A - Diagnostic reagent - Google Patents

Diagnostic reagent

Info

Publication number
GB1078939A
GB1078939A GB5168864A GB5168864A GB1078939A GB 1078939 A GB1078939 A GB 1078939A GB 5168864 A GB5168864 A GB 5168864A GB 5168864 A GB5168864 A GB 5168864A GB 1078939 A GB1078939 A GB 1078939A
Authority
GB
United Kingdom
Prior art keywords
hcg
antibody
diagnostic reagent
animal
drop
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5168864A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Charles Pfizer and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc
Publication of GB1078939A publication Critical patent/GB1078939A/en
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/44—Antibodies bound to carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A diagnostic reagent, suitable for pregnancy determination by agglutination with human chorionic gonadotropin (HCG), comprises an antibody for HCG adsorbed on the surface of polystyrene particles which are in suspension and have an average diameter of 0.15-0.60 microns. The antibody may be first formed by injecting an animal with HCG, subsequently bleeding the animal and recovering the elaborated antibody from the blood. By mixing a drop of urine with a drop of reagent, pregnancy is indicated by visible agglutination in 30-60 secs.
GB5168864A 1964-08-12 1964-12-18 Diagnostic reagent Expired GB1078939A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38917764A 1964-08-12 1964-08-12
US47899965A 1965-08-11 1965-08-11

Publications (1)

Publication Number Publication Date
GB1078939A true GB1078939A (en) 1967-08-09

Family

ID=27012580

Family Applications (2)

Application Number Title Priority Date Filing Date
GB5168864A Expired GB1078939A (en) 1964-08-12 1964-12-18 Diagnostic reagent
GB4451865A Expired GB1086478A (en) 1964-08-12 1965-10-20 Anti-protein to human chorionic gonadotrophin

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB4451865A Expired GB1086478A (en) 1964-08-12 1965-10-20 Anti-protein to human chorionic gonadotrophin

Country Status (2)

Country Link
BE (1) BE684708A (en)
GB (2) GB1078939A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2353858A1 (en) * 1976-06-01 1977-12-30 Warner Lambert Co PREGNANCY TEST BY DIRECT AGGLUTINATION
FR2366569A1 (en) * 1976-09-29 1978-04-28 Mochida Pharm Co Ltd IMMUNOCHEMICAL PROCESS AND REAGENTS FOR THE DOSAGE OF HAPTENE

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310508A (en) * 1979-06-19 1982-01-12 Siber George Diagnostic test and reagent therefor

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2353858A1 (en) * 1976-06-01 1977-12-30 Warner Lambert Co PREGNANCY TEST BY DIRECT AGGLUTINATION
FR2366569A1 (en) * 1976-09-29 1978-04-28 Mochida Pharm Co Ltd IMMUNOCHEMICAL PROCESS AND REAGENTS FOR THE DOSAGE OF HAPTENE

Also Published As

Publication number Publication date
BE684708A (en) 1967-01-30
GB1086478A (en) 1967-10-11

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