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GB1058193A - -a-carboline derivatives - Google Patents

-a-carboline derivatives

Info

Publication number
GB1058193A
GB1058193A GB432263A GB432263A GB1058193A GB 1058193 A GB1058193 A GB 1058193A GB 432263 A GB432263 A GB 432263A GB 432263 A GB432263 A GB 432263A GB 1058193 A GB1058193 A GB 1058193A
Authority
GB
United Kingdom
Prior art keywords
general formula
carbon atoms
pharmaceutically acceptable
lower alkyl
alkyl containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB432263A
Inventor
Robert Geoffrey Willi Spickett
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Smith Kline and French Laboratories Ltd
Original Assignee
Smith Kline and French Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline and French Laboratories Ltd filed Critical Smith Kline and French Laboratories Ltd
Priority to GB432263A priority Critical patent/GB1058193A/en
Publication of GB1058193A publication Critical patent/GB1058193A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The invention comprises compounds of the general formula <FORM:1058193/C2/1> and pharmaceutically acceptable acid addition salts thereof, wherein R1 is lower alkyl containing 1-4 carbon atoms or aralkyl, R2 is lower alkyl containing 1-4 carbon atoms and n is 2, 3 or 4, and the preparation thereof by reacting an alkali metal salt of a gammacarboline represented by the general formula <FORM:1058193/C2/2> with a reactive halogen compound of the general formula <FORM:1058193/C2/3> wherein X is halogen and, if desired, converting the resulting compound into a pharmaceutically acceptable acid addition salt thereof by treatment with the appropriate acid.
GB432263A 1963-02-01 1963-02-01 -a-carboline derivatives Expired GB1058193A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB432263A GB1058193A (en) 1963-02-01 1963-02-01 -a-carboline derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB432263A GB1058193A (en) 1963-02-01 1963-02-01 -a-carboline derivatives

Publications (1)

Publication Number Publication Date
GB1058193A true GB1058193A (en) 1967-02-08

Family

ID=9774993

Family Applications (1)

Application Number Title Priority Date Filing Date
GB432263A Expired GB1058193A (en) 1963-02-01 1963-02-01 -a-carboline derivatives

Country Status (1)

Country Link
GB (1) GB1058193A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663456A (en) * 1985-09-16 1987-05-05 American Home Products Corporation 2-(substituted piperazinylalkyl)β-carbolines useful in treatment of psychological disorders
RU2407744C2 (en) * 2008-12-19 2010-12-27 Андрей Александрович Иващенко Ligands of alpha-adrenoceptors, dopamine, histamine, imidazoline and serotonin receptors and use thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663456A (en) * 1985-09-16 1987-05-05 American Home Products Corporation 2-(substituted piperazinylalkyl)β-carbolines useful in treatment of psychological disorders
RU2407744C2 (en) * 2008-12-19 2010-12-27 Андрей Александрович Иващенко Ligands of alpha-adrenoceptors, dopamine, histamine, imidazoline and serotonin receptors and use thereof

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