[go: up one dir, main page]

FR3138295B1 - Method for monitoring a microneedle biochemical sensor - Google Patents

Method for monitoring a microneedle biochemical sensor Download PDF

Info

Publication number
FR3138295B1
FR3138295B1 FR2207791A FR2207791A FR3138295B1 FR 3138295 B1 FR3138295 B1 FR 3138295B1 FR 2207791 A FR2207791 A FR 2207791A FR 2207791 A FR2207791 A FR 2207791A FR 3138295 B1 FR3138295 B1 FR 3138295B1
Authority
FR
France
Prior art keywords
sensor
microneedle
analyte
monitoring
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR2207791A
Other languages
French (fr)
Other versions
FR3138295A1 (en
Inventor
Khaled Jarri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wizp No AS
Original Assignee
PKvitality SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PKvitality SAS filed Critical PKvitality SAS
Priority to FR2207791A priority Critical patent/FR3138295B1/en
Publication of FR3138295A1 publication Critical patent/FR3138295A1/en
Application granted granted Critical
Publication of FR3138295B1 publication Critical patent/FR3138295B1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14507—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood
    • A61B5/1451—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid
    • A61B5/14514—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue specially adapted for measuring characteristics of body fluids other than blood for interstitial fluid using means for aiding extraction of interstitial fluid, e.g. microneedles or suction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
    • A61B5/053—Measuring electrical impedance or conductance of a portion of the body
    • A61B5/0538—Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; Determining position of diagnostic devices within or on the body of the patient
    • A61B5/061—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body
    • A61B5/063—Determining position of a probe within the body employing means separate from the probe, e.g. sensing internal probe position employing impedance electrodes on the surface of the body using impedance measurements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; Determining position of diagnostic devices within or on the body of the patient
    • A61B5/065—Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe
    • A61B5/068—Determining position of the probe employing exclusively positioning means located on or in the probe, e.g. using position sensors arranged on the probe using impedance sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A61B5/14735—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter comprising an immobilised reagent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Human Computer Interaction (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

L’invention concerne un procédé de surveillance d’un capteur (2) biochimique à microaiguilles connecté de manière amovible à un boitier (9), le boitier (9) comprenant une unité de commande (7), le capteur (2) comprenant plusieurs microaiguilles enfoncées dans la peau d’un utilisateur pour être contact avec un liquide interstitiel dans lequel se trouve un analyte, les microaiguilles constituant des électrodes pour la mesure de la concentration de l’analyte, au moins une microaiguille constituant une électrode de travail du capteur (2), l’électrode de travail étant recouverte d’un matériau réactif apte à réagir avec l’analyte , le procédé comprenant les étapes suivantes mises en œuvre par l’unité de commande (7) : - alimentation du capteur (2) à microaiguilles au moyen d’une tension d’excitation sinusoïdale ayant une valeur moyenne qui correspond à une tension de polarisation propre au capteur (2) pour la mesure de l’analyte ; - détermination, au cours de l’alimentation du capteur (2) d’une première impédance liée à l’enfoncement des électrodes dans la peau et au capteur (2). Figure pour l’abrégé : FIGURE 1The invention relates to a method for monitoring a biochemical microneedle sensor (2) removably connected to a housing (9), the housing (9) comprising a control unit (7), the sensor (2) comprising several microneedles inserted into the skin of a user to be in contact with an interstitial liquid in which an analyte is located, the microneedles constituting electrodes for measuring the concentration of the analyte, at least one microneedle constituting a working electrode of the sensor (2), the working electrode being covered with a reactive material capable of reacting with the analyte, the method comprising the following steps implemented by the control unit (7): - supplying the microneedle sensor (2) with a sinusoidal excitation voltage having an average value which corresponds to a bias voltage specific to the sensor (2) for measuring the analyte; - determination, during the supply of the sensor (2) of a first impedance linked to the insertion of the electrodes into the skin and to the sensor (2). Figure for the abstract: FIGURE 1

FR2207791A 2022-07-28 2022-07-28 Method for monitoring a microneedle biochemical sensor Active FR3138295B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR2207791A FR3138295B1 (en) 2022-07-28 2022-07-28 Method for monitoring a microneedle biochemical sensor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR2207791A FR3138295B1 (en) 2022-07-28 2022-07-28 Method for monitoring a microneedle biochemical sensor
FR2207791 2022-07-28

Publications (2)

Publication Number Publication Date
FR3138295A1 FR3138295A1 (en) 2024-02-02
FR3138295B1 true FR3138295B1 (en) 2025-04-04

Family

ID=84053177

Family Applications (1)

Application Number Title Priority Date Filing Date
FR2207791A Active FR3138295B1 (en) 2022-07-28 2022-07-28 Method for monitoring a microneedle biochemical sensor

Country Status (1)

Country Link
FR (1) FR3138295B1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006520251A (en) * 2003-03-06 2006-09-07 ライフスキャン・インコーポレイテッド System and method for piercing skin tissue
FR3059886B1 (en) 2016-12-09 2021-04-09 Pk Paris BODY SURVEILLANCE DEVICE
EP3861933A1 (en) * 2020-02-05 2021-08-11 PKvitality Device for measuring analyte and driven depth of microneedles in the skin
CN114748038A (en) * 2022-03-22 2022-07-15 中山大学 Sheet-like microneedle sensor and its preparation method and test method

Also Published As

Publication number Publication date
FR3138295A1 (en) 2024-02-02

Similar Documents

Publication Publication Date Title
Baldwin Recent advances in electrochemical detection in capillary electrophoresis
US4805624A (en) Low-potential electrochemical redox sensors
US6275717B1 (en) Device and method of calibrating and testing a sensor for in vivo measurement of an analyte
JP4817692B2 (en) Analysis equipment
Li et al. Simultaneous determination of ethamsylate, tramadol and lidocaine in human urine by capillary electrophoresis with electrochemiluminescence detection
Lunte et al. Pharmaceutical and biomedical applications of capillary electrophoresis/electrochemistry
RU2009143880A (en) DEVICE FOR INCREASING SKIN PERMEABILITY FOR DETECTION OF ANALYTES OR TRANSDERMAL DELIVERY OF MEDICINES
CA2358993A1 (en) Small volume in vitro analyte sensor and related methods
FR2390726A1 (en) MEASUREMENT PROBE FOR DETERMINING THE CONCENTRATION OF IONS IN LIQUIDS
JP2006167428A (en) Analyte extraction device, analyzer, analyte extraction method, and analysis method
FR3138295B1 (en) Method for monitoring a microneedle biochemical sensor
WO2002052254A1 (en) Electronic tongue as ozone detector
EP0617279B1 (en) Method for monitoring purification treatment in plating baths
US4666565A (en) Gas sensor and method
WO1995000838A1 (en) Determining gas concentration
Jin et al. Determination of clozapine by capillary zone electrophoresis following end‐column amperometric detection with simplified capillary/electrode alignment
US4952300A (en) Multiparameter analytical electrode structure and method of measurement
US4798655A (en) Multiparameter analytical electrode structure and method of measurement
EP2708881A1 (en) Biosensor calibration method
Martínez‐Paredes et al. Lead Sensor Using Gold Nanostructured Screen‐Printed Carbon Electrodes as Transducers
EP0630204B1 (en) Measuring sulfides within a periodontal pocket
JP4987527B2 (en) Skin permeability measurement method, component concentration analysis method, skin permeability measurement device, and component concentration analysis device
KR20170040918A (en) Bio sensor and sensing method thereof
JP2003075393A (en) Diaphragm electrode
EP0162622A2 (en) Gas sensor such as for carbon dioxide in the presence of oxygen

Legal Events

Date Code Title Description
PLFP Fee payment

Year of fee payment: 2

PLSC Publication of the preliminary search report

Effective date: 20240202

TP Transmission of property

Owner name: WIZP AS, NO

Effective date: 20240312

PLFP Fee payment

Year of fee payment: 3

PLFP Fee payment

Year of fee payment: 4