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FR2868421B1 - Nouveaux benzothiazoles et leur utilisation comme medicaments - Google Patents

Nouveaux benzothiazoles et leur utilisation comme medicaments

Info

Publication number
FR2868421B1
FR2868421B1 FR0403421A FR0403421A FR2868421B1 FR 2868421 B1 FR2868421 B1 FR 2868421B1 FR 0403421 A FR0403421 A FR 0403421A FR 0403421 A FR0403421 A FR 0403421A FR 2868421 B1 FR2868421 B1 FR 2868421B1
Authority
FR
France
Prior art keywords
medicaments
benzothiazoles
novel
novel benzothiazoles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0403421A
Other languages
English (en)
Other versions
FR2868421A1 (fr
Inventor
Stephanie Deprets
Anke Steinmetz
Boniface Odile Angouillant
Danel Bezard
Jidong Zhang
Yannick Benedetti
Francois Clerc
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0403421A priority Critical patent/FR2868421B1/fr
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Priority to JP2007505593A priority patent/JP2007530644A/ja
Priority to SG200902030-6A priority patent/SG151306A1/en
Priority to AU2005232012A priority patent/AU2005232012A1/en
Priority to KR1020067022907A priority patent/KR20070007885A/ko
Priority to CA002560683A priority patent/CA2560683A1/fr
Priority to PCT/FR2005/000761 priority patent/WO2005097787A2/fr
Priority to EP05744302A priority patent/EP1745044A2/fr
Priority to BRPI0508182-3A priority patent/BRPI0508182A/pt
Priority to CNA2005800140735A priority patent/CN1950369A/zh
Publication of FR2868421A1 publication Critical patent/FR2868421A1/fr
Priority to IL178259A priority patent/IL178259A0/en
Priority to US11/536,757 priority patent/US7632952B2/en
Application granted granted Critical
Publication of FR2868421B1 publication Critical patent/FR2868421B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
FR0403421A 2004-04-01 2004-04-01 Nouveaux benzothiazoles et leur utilisation comme medicaments Expired - Fee Related FR2868421B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR0403421A FR2868421B1 (fr) 2004-04-01 2004-04-01 Nouveaux benzothiazoles et leur utilisation comme medicaments
BRPI0508182-3A BRPI0508182A (pt) 2004-04-01 2005-03-30 benzotiazóis e sua utilização como medicamentos
AU2005232012A AU2005232012A1 (en) 2004-04-01 2005-03-30 Novel benzothiazoles and the use thereof as medicaments
KR1020067022907A KR20070007885A (ko) 2004-04-01 2005-03-30 신규한 벤조티아졸 및 의약으로서의 그의 용도
CA002560683A CA2560683A1 (fr) 2004-04-01 2005-03-30 Derives de benzothiazoles capables de moduler l'activite des cdk et leur utilisation comme agents anticancereux
PCT/FR2005/000761 WO2005097787A2 (fr) 2004-04-01 2005-03-30 Derives de benzothiazoles capables de moduler l’activite des cdk et leur utilisation comme agents anticancereux
JP2007505593A JP2007530644A (ja) 2004-04-01 2005-03-30 新規ベンゾチアゾール及びその医薬としての使用
SG200902030-6A SG151306A1 (en) 2004-04-01 2005-03-30 Novel benzothiazoles and the use thereof as medicaments
CNA2005800140735A CN1950369A (zh) 2004-04-01 2005-03-30 新型苯并噻唑类及其作为药物的用途
EP05744302A EP1745044A2 (fr) 2004-04-01 2005-03-30 Derives de benzothiazoles capables de moduler l'activité des cdk et leur utilisation comme agents anticancereux
IL178259A IL178259A0 (en) 2004-04-01 2006-09-21 Novel benzothiazoles and the use thereof as medicaments
US11/536,757 US7632952B2 (en) 2004-04-01 2006-09-29 Benzothiazoles and the use thereof as medicaments

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0403421A FR2868421B1 (fr) 2004-04-01 2004-04-01 Nouveaux benzothiazoles et leur utilisation comme medicaments

Publications (2)

Publication Number Publication Date
FR2868421A1 FR2868421A1 (fr) 2005-10-07
FR2868421B1 true FR2868421B1 (fr) 2008-08-01

Family

ID=34946087

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0403421A Expired - Fee Related FR2868421B1 (fr) 2004-04-01 2004-04-01 Nouveaux benzothiazoles et leur utilisation comme medicaments

Country Status (12)

Country Link
US (1) US7632952B2 (fr)
EP (1) EP1745044A2 (fr)
JP (1) JP2007530644A (fr)
KR (1) KR20070007885A (fr)
CN (1) CN1950369A (fr)
AU (1) AU2005232012A1 (fr)
BR (1) BRPI0508182A (fr)
CA (1) CA2560683A1 (fr)
FR (1) FR2868421B1 (fr)
IL (1) IL178259A0 (fr)
SG (1) SG151306A1 (fr)
WO (1) WO2005097787A2 (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8236338B2 (en) 2004-07-13 2012-08-07 The University Of Tennessee Research Foundation Adhesive composition for carrying therapeutic agents as delivery vehicle on coatings applied to vascular grafts
FR2891273B1 (fr) * 2005-09-27 2007-11-23 Aventis Pharma Sa NOUVEAUX DERIVES BENZIMIDAZOLES ET BENZOTHIAZOLES, LEUR PREPARATION ET LEUR UTILISATION PHARMACEUTIQUE NOTAMMENT COMME INHIBITEURS DE CMet
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
US20070112589A1 (en) * 2005-11-17 2007-05-17 Searete Llc, A Limited Liability Corporation Of The State Of Delaware User interface for providing assistance related to health
RU2308270C1 (ru) * 2006-04-13 2007-10-20 Михаил Владимирович Кутушов Лекарственное средство
SG175609A1 (en) * 2006-10-09 2011-11-28 Takeda Pharmaceutical Kinase inhibitors
JP2010505961A (ja) * 2006-10-09 2010-02-25 タケダ サン ディエゴ インコーポレイテッド キナーゼ阻害剤
FR2922550B1 (fr) * 2007-10-19 2009-11-27 Sanofi Aventis Nouveaux derives de 6-aryl/heteroalkyloxy benzothiazole et benzimidazole, application comme medicaments, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de cmet
CN102391207B (zh) * 2011-07-26 2014-04-09 贵州大学 N-(2-(取代苯并噻唑-2-氨基甲酰基)-苯基)-苯甲酰胺及其制备方法和用途
US9605175B2 (en) 2012-10-29 2017-03-28 Ariste Medical, Llc Polymer coating compositions and coated products
AU2015249769A1 (en) 2014-04-22 2016-11-10 Ariste Medical, Llc. Methods and processes for application of drug delivery polymeric coatings

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2541752A1 (de) 1975-09-19 1977-03-24 Hoechst Ag Anthelminthisch wirksame 2-carbalkoxyamino-5(6)-phenyl-sulfonyloxy- benzimidazole und verfahren zu ihrer herstellung
DE3247615A1 (de) * 1982-12-23 1984-07-05 Hoechst Ag, 6230 Frankfurt Substituierte phenylsulfonyloxybenzimidazolcarbaminate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB9216298D0 (en) 1991-08-15 1992-09-16 Ici Plc Piperidine derivatives
JP2001522800A (ja) * 1997-11-10 2001-11-20 ブリストル−マイヤーズ スクイブ カンパニー ベンゾチアゾールたんぱくチロシン・キナーゼ抑制剤
GB9823871D0 (en) * 1998-10-30 1998-12-23 Pharmacia & Upjohn Spa 2-Amino-thiazole derivatives, process for their preparation, and their use as antitumour agents
GB9900752D0 (en) 1999-01-15 1999-03-03 Angiogene Pharm Ltd Benzimidazole vascular damaging agents
CA2398754A1 (fr) * 2000-02-07 2001-08-09 Abbott Gmbh & Co. Kg Derives de 2-benzothiazolyle uree et leur utilisation en tant qu'inhibiteurs de proteine kinase
WO2002076454A1 (fr) 2001-03-26 2002-10-03 Unisearch Limited Methode de traitement de cancers et compositions appropriees
EP1298125A1 (fr) * 2001-09-26 2003-04-02 Aventis Pharma S.A. Benzimidazoles substitués et leur usage comme traitement du cancer
EP1388341A1 (fr) * 2002-08-07 2004-02-11 Aventis Pharma Deutschland GmbH Dérivés héteroaromatiques acylamino substitués et leur utilisation en tant que medicaments
FR2891273B1 (fr) 2005-09-27 2007-11-23 Aventis Pharma Sa NOUVEAUX DERIVES BENZIMIDAZOLES ET BENZOTHIAZOLES, LEUR PREPARATION ET LEUR UTILISATION PHARMACEUTIQUE NOTAMMENT COMME INHIBITEURS DE CMet

Also Published As

Publication number Publication date
WO2005097787A2 (fr) 2005-10-20
BRPI0508182A (pt) 2007-08-07
JP2007530644A (ja) 2007-11-01
WO2005097787A3 (fr) 2006-01-26
CA2560683A1 (fr) 2005-10-20
FR2868421A1 (fr) 2005-10-07
CN1950369A (zh) 2007-04-18
US20070093488A1 (en) 2007-04-26
IL178259A0 (en) 2006-12-31
AU2005232012A1 (en) 2005-10-20
US7632952B2 (en) 2009-12-15
EP1745044A2 (fr) 2007-01-24
KR20070007885A (ko) 2007-01-16
SG151306A1 (en) 2009-04-30

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Legal Events

Date Code Title Description
ST Notification of lapse

Effective date: 20121228