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FR284M - Medicinal product based on 6 alpha-methyl-9 alpha-fluoro-11 beta, 17 alpha-dihydroxy-1,4-pregnadiene-3,20-dione for the treatment of amenorrhea. - Google Patents

Medicinal product based on 6 alpha-methyl-9 alpha-fluoro-11 beta, 17 alpha-dihydroxy-1,4-pregnadiene-3,20-dione for the treatment of amenorrhea.

Info

Publication number
FR284M
FR284M FR836743A FR836743A FR284M FR 284 M FR284 M FR 284M FR 836743 A FR836743 A FR 836743A FR 836743 A FR836743 A FR 836743A FR 284 M FR284 M FR 284M
Authority
FR
France
Prior art keywords
alpha
pregnadiene
amenorrhea
dione
dihydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
FR836743A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR821678A external-priority patent/FR1430856A/en
Application filed by Upjohn Co filed Critical Upjohn Co
Priority to FR836743A priority Critical patent/FR284M/en
Application granted granted Critical
Publication of FR284M publication Critical patent/FR284M/en
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
FR836743A 1959-03-18 1960-08-25 Medicinal product based on 6 alpha-methyl-9 alpha-fluoro-11 beta, 17 alpha-dihydroxy-1,4-pregnadiene-3,20-dione for the treatment of amenorrhea. Active FR284M (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR836743A FR284M (en) 1959-03-18 1960-08-25 Medicinal product based on 6 alpha-methyl-9 alpha-fluoro-11 beta, 17 alpha-dihydroxy-1,4-pregnadiene-3,20-dione for the treatment of amenorrhea.

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US800103A US3038914A (en) 1959-03-18 1959-03-18 17-esters of 6-substituted-11-oxygenatedprogesterones
FR821678A FR1430856A (en) 1960-03-17 1960-03-17 Process for the manufacture of esters of steroids more particularly of 17-esters of unsaturated 17alpha-hydroxy-pregnan-3,20-diones
FR836743A FR284M (en) 1959-03-18 1960-08-25 Medicinal product based on 6 alpha-methyl-9 alpha-fluoro-11 beta, 17 alpha-dihydroxy-1,4-pregnadiene-3,20-dione for the treatment of amenorrhea.

Publications (1)

Publication Number Publication Date
FR284M true FR284M (en) 1961-03-13

Family

ID=25177490

Family Applications (1)

Application Number Title Priority Date Filing Date
FR836743A Active FR284M (en) 1959-03-18 1960-08-25 Medicinal product based on 6 alpha-methyl-9 alpha-fluoro-11 beta, 17 alpha-dihydroxy-1,4-pregnadiene-3,20-dione for the treatment of amenorrhea.

Country Status (4)

Country Link
US (1) US3038914A (en)
CH (1) CH398578A (en)
FR (1) FR284M (en)
NL (1) NL6408818A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3125590A (en) * 1964-03-17 Certificate of correction
WO2009045539A2 (en) * 2007-10-05 2009-04-09 Nektar Therapeutics Al, Corporation Oligomer-corticosteroid conjugates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2837464A (en) * 1955-01-11 1958-06-03 Schering Corp Process for production of dienes by corynebacteria
US2875200A (en) * 1954-12-17 1959-02-24 Upjohn Co 9alpha-halo-11beta, 21-dihydroxy-4, 17(20)-pregnadiene-3-one compounds and process of preparing thereof
US2867637A (en) * 1957-05-17 1959-01-06 Upjohn Co 6alpha methyl, 9alpha f, 17alpha oh 1, 4 pregnadiene compounds
US2867638A (en) * 1957-05-17 1959-01-06 Upjohn Co 6-methyl-9alpha fluoro-11 oxygenated pregnenes
US2838496A (en) * 1957-11-29 1958-06-10 Upjohn Co 6-fluoro steroids and process for preparing same
US2838536A (en) * 1957-11-29 1958-06-10 Upjohn Co 6-fluoro 9 alpha-halo-delta4-pregnenes and process for preparing same
US2838538A (en) * 1957-11-29 1958-06-10 Upjohn Co 6-fluoro steroids and process for preparing same
US2892851A (en) * 1958-05-19 1959-06-30 Searle & Co 11-oxygenated derivatives of 9-fluoro-17-acyloxyprogesterones

Also Published As

Publication number Publication date
CH398578A (en) 1966-03-15
NL6408818A (en) 1965-02-25
US3038914A (en) 1962-06-12

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