[go: up one dir, main page]

FR2699171B1 - 2-amino-N [[[4-aminocarbonyl) pyrimidin-2-yl] amino] alkyl] pyrimidine-4-carboxamide derivatives, their preparation and their therapeutic use. - Google Patents

2-amino-N [[[4-aminocarbonyl) pyrimidin-2-yl] amino] alkyl] pyrimidine-4-carboxamide derivatives, their preparation and their therapeutic use.

Info

Publication number
FR2699171B1
FR2699171B1 FR9215037A FR9215037A FR2699171B1 FR 2699171 B1 FR2699171 B1 FR 2699171B1 FR 9215037 A FR9215037 A FR 9215037A FR 9215037 A FR9215037 A FR 9215037A FR 2699171 B1 FR2699171 B1 FR 2699171B1
Authority
FR
France
Prior art keywords
amino
aminocarbonyl
pyrimidin
pyrimidine
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9215037A
Other languages
French (fr)
Other versions
FR2699171A1 (en
Inventor
Pascal George
Benoit Marabout
Jacques Froissant
Jean-Pierre Merly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR9215037A priority Critical patent/FR2699171B1/en
Priority to DE69300162T priority patent/DE69300162T2/en
Priority to AT93401594T priority patent/ATE123025T1/en
Priority to EP93401594A priority patent/EP0577470B1/en
Priority to DK93401594.2T priority patent/DK0577470T3/en
Priority to ES93401594T priority patent/ES2073951T3/en
Priority to IL106213A priority patent/IL106213A/en
Priority to MX9303976A priority patent/MX9303976A/en
Priority to PL93299541A priority patent/PL172583B1/en
Priority to US08/084,493 priority patent/US5330985A/en
Priority to TW82105287A priority patent/TW243448B/zh
Priority to KR1019930012427A priority patent/KR940005619A/en
Priority to CA002099556A priority patent/CA2099556A1/en
Priority to KR1019930012430A priority patent/KR940002173A/en
Priority to RU93033697A priority patent/RU2111963C1/en
Priority to SK699-93A priority patent/SK69993A3/en
Priority to CN93108413A priority patent/CN1100416A/en
Priority to NZ248051A priority patent/NZ248051A/en
Priority to CZ931351A priority patent/CZ282079B6/en
Priority to HU9301937A priority patent/HUT65533A/en
Priority to JP16454493A priority patent/JP3285421B2/en
Priority to FI933064A priority patent/FI933064A7/en
Priority to AU41712/93A priority patent/AU660815B2/en
Priority to NO932418A priority patent/NO932418L/en
Publication of FR2699171A1 publication Critical patent/FR2699171A1/en
Application granted granted Critical
Publication of FR2699171B1 publication Critical patent/FR2699171B1/en
Priority to HU95P/P00445P priority patent/HU211462A9/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR9215037A 1992-07-02 1992-12-14 2-amino-N [[[4-aminocarbonyl) pyrimidin-2-yl] amino] alkyl] pyrimidine-4-carboxamide derivatives, their preparation and their therapeutic use. Expired - Fee Related FR2699171B1 (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
FR9215037A FR2699171B1 (en) 1992-12-14 1992-12-14 2-amino-N [[[4-aminocarbonyl) pyrimidin-2-yl] amino] alkyl] pyrimidine-4-carboxamide derivatives, their preparation and their therapeutic use.
DE69300162T DE69300162T2 (en) 1992-07-03 1993-06-22 2-Amino-N - [[[4- (aminocarbonyl) pyrimidin-2-yl] amino] alkyl] pyrimidine-4-carboxamide derivatives, their preparation and their use in therapeutics.
AT93401594T ATE123025T1 (en) 1992-07-03 1993-06-22 2-AMINO-N-(((4-(AMINOCARBONYL)PYRIMIDINE-2- YL>AMINO>ALKYL>-PYRIMIDINE-4- CARBOXYLIC AMIDE DERIVATIVES, THEIR PRODUCTION AND THEIR APPLICATION IN THERAPEUTICS.
EP93401594A EP0577470B1 (en) 1992-07-03 1993-06-22 2-Amino-N-[[[4-(aminocarbonyl)pyrimidin-2-yl]amino]alkyl]-pyrimidine-4-carboxamide derivates, their preparation and their use in therapeutics
DK93401594.2T DK0577470T3 (en) 1992-07-03 1993-06-22 2-Amino-N (((4- (aminocarbonyl) pyrimidin-2-yl) amino) alkyl) pyrimidine-4-carboxamide derivatives, their preparation and their use in therapy
ES93401594T ES2073951T3 (en) 1992-07-03 1993-06-22 2-AMINO-N DERIVATIVES - (((4- (AMINO CARBONYL) PIRIMIDIN-2-IL) AMINO) ALKYL) PIRIMIDINE-4-CARBOXAMIDE, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS.
MX9303976A MX9303976A (en) 1992-07-03 1993-07-01 DERIVATIVES OF 2-AMINO-N - {{((4- (AMINO CARBONYL) -PIRIMIDIN-2-IL-AMINO) -ALKYL} -PIRIMIDI N-4-CARBOXAMIDE, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS.
PL93299541A PL172583B1 (en) 1992-07-03 1993-07-01 New derivatives of N - [(4-aminopyrimidyl-2) -aminoalkyl] -2-aminopyrimidinecarbonamide-4 and their preparation
US08/084,493 US5330985A (en) 1992-07-03 1993-07-01 2-amino-N-[[4-(aminocarbonyl)pyrimidin-2-yl]amino]-alkyl]pyrimidine-4-carboxamide derivatives, their preparation and pharmaceutical compositions containing them
IL106213A IL106213A (en) 1992-07-03 1993-07-01 2-amino-n- £££4-(aminocarbonyl) pyrimidin-2-yl| amino| alkyl| pyrimidine- 4-carboxamide derivatives, preparation thereof and pharmaceutical compositions containing them
HU9301937A HUT65533A (en) 1992-07-03 1993-07-02 Process for producing 2-amino-pyrimidine-4-carboxamide derivatives and pharmaceutical preparations containing them
CA002099556A CA2099556A1 (en) 1992-07-03 1993-07-02 2-amino-n-¬¬¬4-(aminocarbonyl)pyrimidin-2-yl|amino|alkyl| pyrimidine-4-carboxamide derivatives, preparation thereof and therapeutical application thereof
TW82105287A TW243448B (en) 1992-12-14 1993-07-02
RU93033697A RU2111963C1 (en) 1992-07-03 1993-07-02 2-amino-n- [4-(aminocarbonyl)pyrimidin-2-yl] amino-alkyl pyrimidine-4-carboxamide derivatives, and pharmaceutical composition
SK699-93A SK69993A3 (en) 1992-07-03 1993-07-02 2-amino-n-[[[4-(aminocarbonyl)pyrimidine-2- -yl]amino]alkyl]pyrimidine-4-carboxamide derivatives, process for their preparation and their pharmaceutical compositions
CN93108413A CN1100416A (en) 1992-07-03 1993-07-02 Pyrimidine amide derivatives, their preparation and their application in medicine
NZ248051A NZ248051A (en) 1992-07-03 1993-07-02 2-(substituted amino)-n-[[4-(aminocarbonyl) pyrimidin-2-yl]alkyl]pyrimidine-4-carboxamide derivatives; medicaments and preparatory processes
CZ931351A CZ282079B6 (en) 1992-07-03 1993-07-02 Derivative of 2 amino-n-{/£4-(aminocarbonyl)pyrimidin-2-yl|amino/alkyl} pyrimidine-4-carboxamide, process of its preparation, and pharmaceutical preparation in which it is comprised
KR1019930012427A KR940005619A (en) 1992-07-03 1993-07-02 2-amino-N-[[[4- (aminocarbonyl) pyrimidin-2-yl] amino] alkyl] pyrimidine-4-carboxyamide derivative, its use in preparation and treatment
JP16454493A JP3285421B2 (en) 1992-07-03 1993-07-02 2-Amino-N-[[[4- (aminocarbonyl) pyrimidin-2-yl] amino] alkyl] pyrimidine-4-carboxamide derivative, its production and application to medicine
FI933064A FI933064A7 (en) 1992-07-03 1993-07-02 2-Amino-N-(((4-(aminocarbonyl)pyrimidin2-yl)amino)alkyl)pyrimidine-4-carboxamide derivatives, their preparation and therapeutic use
AU41712/93A AU660815B2 (en) 1992-07-03 1993-07-02 2-amino-N-(((4-(aminocarbonyl)pyrimidin-2-yl)amino)alkyl) pyrimidine-4-carboxamide derivatives preparation thereof and therapeutical application thereof
NO932418A NO932418L (en) 1992-07-03 1993-07-02 Pyrimidine derivatives, processes for their preparation and therapeutic use thereof
KR1019930012430A KR940002173A (en) 1992-07-02 1993-07-02 New coagulation-flocculation method
HU95P/P00445P HU211462A9 (en) 1992-07-03 1995-06-27 2-amino-n-[[[4-(amino-carbonyl)-pyrimidin-2-yl]-amino]-alkyl]-pyrimidine-4-carboxamide derivatives, process for producing them, and pharmaceutical use of them

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9215037A FR2699171B1 (en) 1992-12-14 1992-12-14 2-amino-N [[[4-aminocarbonyl) pyrimidin-2-yl] amino] alkyl] pyrimidine-4-carboxamide derivatives, their preparation and their therapeutic use.

Publications (2)

Publication Number Publication Date
FR2699171A1 FR2699171A1 (en) 1994-06-17
FR2699171B1 true FR2699171B1 (en) 1995-02-03

Family

ID=9436559

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9215037A Expired - Fee Related FR2699171B1 (en) 1992-07-02 1992-12-14 2-amino-N [[[4-aminocarbonyl) pyrimidin-2-yl] amino] alkyl] pyrimidine-4-carboxamide derivatives, their preparation and their therapeutic use.

Country Status (2)

Country Link
FR (1) FR2699171B1 (en)
TW (1) TW243448B (en)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2656609B1 (en) * 1989-12-28 1992-03-27 Synthelabo 2-AMINOPYRIMIDINE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
FR2667317B1 (en) * 1990-10-02 1992-12-04 Synthelabo 2-AMINOPYRIMIDINE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
FR2675799B1 (en) * 1991-04-24 1993-12-24 Synthelabo 2-AMINOPYRIMIDINE-4-CARBOXAMIDE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.

Also Published As

Publication number Publication date
TW243448B (en) 1995-03-21
FR2699171A1 (en) 1994-06-17

Similar Documents

Publication Publication Date Title
FR2696176B1 (en) Piperidine derivatives, their preparation and their therapeutic application.
DE69804743D1 (en) Pyrazolo [4,3-d] pyrimidine derivatives and pharmaceutical preparations containing them
ATE136542T1 (en) PYRIMIDINES AND THEIR PHARMACEUTICALLY USABLE SALTS AND THEIR USE AS MEDICINAL PRODUCTS
MY105944A (en) Antiviral pyrimidine nucleosides.
IL98110A0 (en) N-(3-fluoro-2-phosphonylmethoxypropyl)derivatives of purine and pyrimidine heterocyclic bases,their preparation and use
FI981709A0 (en) Process for the preparation of 5-substituted 2-amino-4-oxo-pyrrolo [2,3-d] pyrimidines
FR2696744B1 (en) 2-Pyrrolidone derivatives, their preparation process and their therapeutic applications.
NO904901D0 (en) N-SUBSTITUTED DERIVATIVES OF 3R, 4R-ETHYL - ((1-METHYL-1H-IMIDAZOL-5-YL) METHYL) -2-PYRROLIDINON.
DE69126469D1 (en) Pyrimidine nucleoside derivatives and antiviral agents containing these derivatives as an active ingredient
DZ1718A1 (en) Piperidine derivatives, their preparation and their therapeutic application.
BR9605046B1 (en) n- (pyrimidinyl) -benzenesulfonamide compounds and pharmaceutical preparation containing them.
TR27833A (en) "Pour-on" formulation for the application of anthelmintics.
FR2699171B1 (en) 2-amino-N [[[4-aminocarbonyl) pyrimidin-2-yl] amino] alkyl] pyrimidine-4-carboxamide derivatives, their preparation and their therapeutic use.
FR2693195B1 (en) 2-amino-N - [[[(4-aminocarbonyl) pyrimidin-2-yl] amino] alkyl] pyrimidine-4-carboxamide derivatives, their preparation and their therapeutic use.
FR2699920B1 (en) Imidazo [2,1-b] benzothiazole-3-acetamide derivatives, their preparation and their therapeutic use.
FR2697253B1 (en) 2-Aminopyrimidine-4-carboxamide derivatives, their preparation and their therapeutic use.
FR2714291B1 (en) Application of pyridone derivatives as anesthetic drugs.
ZA90830B (en) Pyrimidinetrione derivatives,processes for their preparation,agents containing them and their use as agents for combating pests
FR2716193B1 (en) 1 [2- (1h-inden-3-yl) ethyl] -4- (naphthalen-1-yl) piperazine derivatives, their preparation and their therapeutic use.
FR2700546B1 (en) Imidazo [2,1-b] benzoxazole-3-acetamide derivatives, their preparation and their therapeutic use.
OA08742A (en) Pyrimidine derivatives.
FR2699534B1 (en) Alpha-thienyl-piperidine-1-ethanol derivatives, their preparation and their therapeutic use.
FR2700543B1 (en) Salts of 4-pyrimidinone derivatives, their preparation and their therapeutic use.
FR2699921B1 (en) 2- (Thien-2-yl) imidazo [2,1-b] benzothiazole-3-acetic acid derivatives, their preparation and their therapeutic use.
FR2703355B1 (en) 2-Aminopyrimidine-4-carboxamide derivatives, their preparation and their therapeutic use.

Legal Events

Date Code Title Description
ST Notification of lapse