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FR2642767B1 - VECTORS FOR EXPRESSION OF HETEROLOGOUS PROTEINS IN EUKARYOTIC CELLS, CELL LINES OBTAINED AND PROCESS FOR THEIR PREPARATION - Google Patents

VECTORS FOR EXPRESSION OF HETEROLOGOUS PROTEINS IN EUKARYOTIC CELLS, CELL LINES OBTAINED AND PROCESS FOR THEIR PREPARATION

Info

Publication number
FR2642767B1
FR2642767B1 FR8900599A FR8900599A FR2642767B1 FR 2642767 B1 FR2642767 B1 FR 2642767B1 FR 8900599 A FR8900599 A FR 8900599A FR 8900599 A FR8900599 A FR 8900599A FR 2642767 B1 FR2642767 B1 FR 2642767B1
Authority
FR
France
Prior art keywords
vectors
expression
preparation
cell lines
eukaryotic cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8900599A
Other languages
French (fr)
Other versions
FR2642767A1 (en
Inventor
De La Salle Henri
Faure Therese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Original Assignee
Transgene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene SA filed Critical Transgene SA
Priority to FR8900599A priority Critical patent/FR2642767B1/en
Publication of FR2642767A1 publication Critical patent/FR2642767A1/en
Application granted granted Critical
Publication of FR2642767B1 publication Critical patent/FR2642767B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/644—Coagulation factor IXa (3.4.21.22)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21022—Coagulation factor IXa (3.4.21.22)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FR8900599A 1989-01-19 1989-01-19 VECTORS FOR EXPRESSION OF HETEROLOGOUS PROTEINS IN EUKARYOTIC CELLS, CELL LINES OBTAINED AND PROCESS FOR THEIR PREPARATION Expired - Fee Related FR2642767B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8900599A FR2642767B1 (en) 1989-01-19 1989-01-19 VECTORS FOR EXPRESSION OF HETEROLOGOUS PROTEINS IN EUKARYOTIC CELLS, CELL LINES OBTAINED AND PROCESS FOR THEIR PREPARATION

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8900599A FR2642767B1 (en) 1989-01-19 1989-01-19 VECTORS FOR EXPRESSION OF HETEROLOGOUS PROTEINS IN EUKARYOTIC CELLS, CELL LINES OBTAINED AND PROCESS FOR THEIR PREPARATION

Publications (2)

Publication Number Publication Date
FR2642767A1 FR2642767A1 (en) 1990-08-10
FR2642767B1 true FR2642767B1 (en) 1993-10-01

Family

ID=9377863

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8900599A Expired - Fee Related FR2642767B1 (en) 1989-01-19 1989-01-19 VECTORS FOR EXPRESSION OF HETEROLOGOUS PROTEINS IN EUKARYOTIC CELLS, CELL LINES OBTAINED AND PROCESS FOR THEIR PREPARATION

Country Status (1)

Country Link
FR (1) FR2642767B1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4000596A1 (en) * 1989-10-27 1991-05-02 Rieleit Myung Soon VEHICLE, IN PARTICULAR AIR OR WATER VEHICLE
US5820868A (en) 1993-12-09 1998-10-13 Veterinary Infectious Disease Organization Recombinant protein production in bovine adenovirus expression vector system
CA2294649C (en) 1997-06-23 2007-09-25 University Of Saskatchewan Bovine adenovirus type 3 genome
US6180108B1 (en) * 1998-12-10 2001-01-30 Bayer Corporation Vectors having terminal repeat sequence of Epstein-Barr virus
AU2001263689B2 (en) 2000-05-31 2007-03-22 University Of Saskatchewan Modified bovine adenovirus having altered tropism
CA2415347A1 (en) * 2000-07-14 2002-01-24 University Of Saskatchewan Adenovirus vectors comprising introns

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI86885C (en) * 1984-04-20 1992-10-26 Genentech Inc Method for Preparation of Human Recombinant Factor VIII and Nucleic Acid Sequences and Vectors Used thereto
FR2573436B1 (en) * 1984-11-20 1989-02-17 Pasteur Institut RECOMBINANT DNA COMPRISING A NUCLEOTIDE SEQUENCE ENCODING A DETERMINED POLYPEPTIDE UNDER THE CONTROL OF AN ADENOVIRUS PROMOTER, VECTORS CONTAINING THIS RECOMBINANT DNA, EUKARYOT CELLS TRANSFORMED BY THIS RECOMBINANT DNA, THE CONSTITUTION OF VACCINES
EP0215923B1 (en) * 1985-03-22 1990-12-27 Chiron Corporation Expression of tpa in mammalian cells
FR2600334B1 (en) * 1986-06-23 1989-05-12 Transgene Sa VECTORS FOR INTEGRATION INTO EUKARYOTIC CELLS PROVIDING EXPRESSION OF FACTOR IX, CELULLAR LINES OBTAINED AND PROCESS FOR THEIR PREPARATION

Also Published As

Publication number Publication date
FR2642767A1 (en) 1990-08-10

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Legal Events

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ST Notification of lapse