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FR2506313A1 - Derives de l'acide n-acetylneuraminique et leur preparation - Google Patents

Derives de l'acide n-acetylneuraminique et leur preparation

Info

Publication number
FR2506313A1
FR2506313A1 FR8208946A FR8208946A FR2506313A1 FR 2506313 A1 FR2506313 A1 FR 2506313A1 FR 8208946 A FR8208946 A FR 8208946A FR 8208946 A FR8208946 A FR 8208946A FR 2506313 A1 FR2506313 A1 FR 2506313A1
Authority
FR
France
Prior art keywords
preparation
acetylneuraminic acid
acid derivatives
aralkyl
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8208946A
Other languages
English (en)
Other versions
FR2506313B1 (fr
Inventor
Haruo Ogura
Kimio Furuhata
Toshiaki Osawa
Satoshi Toyoshima
Yoshiyasu Shitori
Masayoshi Ito
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KANTO ISHI PHARMA CO Ltd
Original Assignee
KANTO ISHI PHARMA CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP56077672A external-priority patent/JPS6019917B2/ja
Priority claimed from JP56099364A external-priority patent/JPS6053039B2/ja
Application filed by KANTO ISHI PHARMA CO Ltd filed Critical KANTO ISHI PHARMA CO Ltd
Publication of FR2506313A1 publication Critical patent/FR2506313A1/fr
Application granted granted Critical
Publication of FR2506313B1 publication Critical patent/FR2506313B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NOUVEAUX DERIVES DE L'ACIDE N-ACETYLNEURAMINIQUE DE FORMULE GENERALE I : (CF DESSIN DANS BOPI) DANS LAQUELLE R REPRESENTE UN ATOME D'HYDROGENE, UN ALKYLE INFERIEUR, UN GROUPEMENT ARALKYLE OU ARYLE, OU UN GROUPEMENT ARALKYLE OU ARYLE SUBSTITUE PAR UN ALKYLE INFERIEUR, R REPRESENTE UN RESIDU D'UN NUCLEOSIDE OU D'UN GLUCOSE ET R ET R REPRESENTENT INDEPENDAMMENT UN ATOME D'HYDROGENE OU UN GROUPEMENT ACETYLE, ET LEUR PROCEDE DE PREPARATION. CES COMPOSES SONT UTILISABLES NOTAMMENT COMME IMMUNO-SUPPRESSEURS.
FR8208946A 1981-05-22 1982-05-24 Derives de l'acide n-acetylneuraminique et leur preparation Expired FR2506313B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP56077672A JPS6019917B2 (ja) 1981-05-22 1981-05-22 Ｎ―アセチルノイラミン酸誘導体
JP56099364A JPS6053039B2 (ja) 1981-06-26 1981-06-26 Ｎ−アセチル／イラミン酸誘導体およびその製造方法

Publications (2)

Publication Number Publication Date
FR2506313A1 true FR2506313A1 (fr) 1982-11-26
FR2506313B1 FR2506313B1 (fr) 1985-10-18

Family

ID=26418748

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8208946A Expired FR2506313B1 (fr) 1981-05-22 1982-05-24 Derives de l'acide n-acetylneuraminique et leur preparation

Country Status (5)

Country Link
DE (2) DE3249916C2 (fr)
FR (1) FR2506313B1 (fr)
GB (1) GB2101588B (fr)
HK (1) HK27589A (fr)
SG (1) SG11288G (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2560881A1 (fr) * 1984-03-09 1985-09-13 Kanto Ishi Pharma Co Ltd Derives d'acide sialique, leurs procedes de preparation et leurs applications notamment comme medicament inhibiteur de la metastase des cellules cancereuses
EP0281067A3 (en) * 1987-03-06 1988-12-14 Mect Corporation N-acetyl-3-fluoro-neuraminic acid derivatives and preparation thereof
EP0502827A1 (fr) * 1991-03-06 1992-09-09 Nippon Zoki Pharmaceutical Co., Ltd. Dérivés de l'acide sialique
EP0482584A3 (en) * 1990-10-22 1992-09-09 Mect Corporation Gm3 analogous compound and preparation method thereof

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6287598A (ja) * 1985-10-11 1987-04-22 Mect Corp Ｎ−グリコリルノイラミン酸誘導体
CA1262130A (fr) * 1985-10-11 1989-10-03 Shoji Yoshimura Methode de preparation de derives de l'acide n-glycolylneuraminique
US5034516A (en) * 1987-08-04 1991-07-23 University Of Ottawa Synthetic antigens of sialic acid and derivatives thereof
JPH02145596A (ja) * 1988-11-29 1990-06-05 Mect Corp 活性エステル基を持つシタル酸誘導体
DE4437927C2 (de) * 1994-10-24 1996-09-12 Bosch Gmbh Robert Magnetventilgesteuerte Kraftstoffeinspritzvorrichtung mit einer Einspritzdüse zur Kraftstoffeinspritzung in den Brennraum einer Dieselbrennkraftmaschine

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEMICAL & PHARMACEUTICAL BULLETIN, vol. 30, no. 9, septembre 1982, Pharmaceutical Society of Japan; I. KIJIMA et al.:" Induction of suppressor T cells by neuraminic acid derivatives", pages 3278-3283 *
HOPPE-SEYLER'S Z. PHYSIOL. CHEM., vol. 352, décembre 1971; R. BROSSMER et al.:"On the specificity of neuraminidase", pages 1715-1719 *
NINTH SYMPOSIUM ON NUCLEIC ACIDS CHEMISTRY, no. 10, 28-30 octobre 1981, Tokyo (JP), IRL Press Ltd., Londres (GB); H. OGURA et al.:"Synthetic O-glycosyl nucleoside analogs", pages 23-26 *
THE JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 244, no. 5, 10 mars 1969; R.K. YU et al.:"Configuration of the ketosidic bond of sialic acid", pages 1306-1313 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2560881A1 (fr) * 1984-03-09 1985-09-13 Kanto Ishi Pharma Co Ltd Derives d'acide sialique, leurs procedes de preparation et leurs applications notamment comme medicament inhibiteur de la metastase des cellules cancereuses
EP0281067A3 (en) * 1987-03-06 1988-12-14 Mect Corporation N-acetyl-3-fluoro-neuraminic acid derivatives and preparation thereof
EP0482584A3 (en) * 1990-10-22 1992-09-09 Mect Corporation Gm3 analogous compound and preparation method thereof
EP0502827A1 (fr) * 1991-03-06 1992-09-09 Nippon Zoki Pharmaceutical Co., Ltd. Dérivés de l'acide sialique

Also Published As

Publication number Publication date
GB2101588B (en) 1985-02-13
HK27589A (en) 1989-04-07
SG11288G (en) 1988-07-01
DE3249916C2 (fr) 1992-04-02
DE3219209A1 (de) 1982-12-09
FR2506313B1 (fr) 1985-10-18
GB2101588A (en) 1983-01-19
DE3219209C2 (fr) 1988-03-10

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