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FR2588189B1 - Composition pharmaceutique de type a transition de phase liquide-gel - Google Patents

Composition pharmaceutique de type a transition de phase liquide-gel

Info

Publication number
FR2588189B1
FR2588189B1 FR8514689A FR8514689A FR2588189B1 FR 2588189 B1 FR2588189 B1 FR 2588189B1 FR 8514689 A FR8514689 A FR 8514689A FR 8514689 A FR8514689 A FR 8514689A FR 2588189 B1 FR2588189 B1 FR 2588189B1
Authority
FR
France
Prior art keywords
liquid
pharmaceutical composition
phase transition
gel phase
intended
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8514689A
Other languages
English (en)
Other versions
FR2588189A1 (fr
Inventor
Claude Mazuel
Marie-Claire Friteyre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Merck Sharp and Dohme Chibret SAS
Organon Pharma UK Ltd
Original Assignee
Laboratories Merck Sharp and Dohme Chibret SAS
Merck Sharp and Dohme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratories Merck Sharp and Dohme Chibret SAS, Merck Sharp and Dohme Ltd filed Critical Laboratories Merck Sharp and Dohme Chibret SAS
Priority to FR8514689A priority Critical patent/FR2588189B1/fr
Priority to IE248186A priority patent/IE59464B1/en
Priority to NZ217662A priority patent/NZ217662A/xx
Priority to GR862444A priority patent/GR862444B/el
Priority to US06/911,606 priority patent/US4861760A/en
Priority to IL80156A priority patent/IL80156A/xx
Priority to AU63189/86A priority patent/AU595240B2/en
Priority to CN86106637A priority patent/CN1046094C/zh
Priority to ZA867464A priority patent/ZA867464B/xx
Priority to PT83471A priority patent/PT83471B/pt
Priority to KR1019860008277A priority patent/KR940000229B1/ko
Priority to DE8686402170T priority patent/DE3684121D1/de
Priority to EP86402170A priority patent/EP0227494B1/fr
Priority to JP61233369A priority patent/JPH0667853B2/ja
Priority to DK469886A priority patent/DK170500B1/da
Priority to LU88694C priority patent/LU88694I2/fr
Priority to NO863916A priority patent/NO173212C/no
Priority to DE198686402170T priority patent/DE227494T1/de
Priority to ES8602366A priority patent/ES2002401A6/es
Priority to AT86402170T priority patent/ATE72990T1/de
Priority to FI863990A priority patent/FI91217C/fi
Priority to CA000519753A priority patent/CA1280367C/fr
Publication of FR2588189A1 publication Critical patent/FR2588189A1/fr
Application granted granted Critical
Publication of FR2588189B1 publication Critical patent/FR2588189B1/fr
Priority to HK42594A priority patent/HK42594A/en
Priority to NO1995003C priority patent/NO1995003I1/no
Priority to NL950012C priority patent/NL950012I1/nl
Priority to LV950262A priority patent/LV5725B4/xx
Priority to CY177995A priority patent/CY1779A/xx
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FR8514689A 1985-10-03 1985-10-03 Composition pharmaceutique de type a transition de phase liquide-gel Expired FR2588189B1 (fr)

Priority Applications (27)

Application Number Priority Date Filing Date Title
FR8514689A FR2588189B1 (fr) 1985-10-03 1985-10-03 Composition pharmaceutique de type a transition de phase liquide-gel
IE248186A IE59464B1 (en) 1985-10-03 1986-09-17 Pharmaceutical composition of the type which undergoes liquid-gel phase transition
NZ217662A NZ217662A (en) 1985-10-03 1986-09-23 Liquid aqueous ophthalmic composition containing gellan gum
GR862444A GR862444B (en) 1985-10-03 1986-09-25 Pharmaceutical composition undergoing a liquid-gel phase conversion
US06/911,606 US4861760A (en) 1985-10-03 1986-09-25 Ophthalmological composition of the type which undergoes liquid-gel phase transition
IL80156A IL80156A (en) 1985-10-03 1986-09-25 Pharmaceutical composition of the type which undergoes liquid-gel phase transition
AU63189/86A AU595240B2 (en) 1985-10-03 1986-09-26 Pharmaceutical composition of the type which undergoes liquid-gel phase transition
CN86106637A CN1046094C (zh) 1985-10-03 1986-09-30 多糖体用于制备原位胶凝的眼科组合物的用途
ZA867464A ZA867464B (en) 1985-10-03 1986-09-30 Pharmaceutical composition of the type which undergoes liquid-gel phase transition
PT83471A PT83471B (pt) 1985-10-03 1986-10-01 Processo para a preparacao de uma composicao farmaceutica do tipo que passa por uma fase de transicao liquido-gel, contendo um polissacarideo
LU88694C LU88694I2 (fr) 1985-10-03 1986-10-02 Timolol ou un sel pharmaceutuquement acceptable de celui-ci en particulier le maléate de timolol en combinaison avec une gomme gélifiante
EP86402170A EP0227494B1 (fr) 1985-10-03 1986-10-02 Composition pharmaceutique du type subissant une transition de phase liquide-gel
JP61233369A JPH0667853B2 (ja) 1985-10-03 1986-10-02 液体−ゲル相転移を起すタイプの医薬組成物
DK469886A DK170500B1 (da) 1985-10-03 1986-10-02 Farmaceutisk præparat, der undergår væske-gel faseovergang
KR1019860008277A KR940000229B1 (ko) 1985-10-03 1986-10-02 생리학적 액체와 접촉하여 겔화되는 약제학적 조성물의 제조방법
NO863916A NO173212C (no) 1985-10-03 1986-10-02 Fremgangsmaate for fremstilling av et oftalmologisk preparat
DE198686402170T DE227494T1 (de) 1985-10-03 1986-10-02 Pharmazeutische zusammensetzung vom fluessig/gel-phasenuebergangstyp.
ES8602366A ES2002401A6 (es) 1985-10-03 1986-10-02 Procedimiento para preparar una composicion farmaceutica del tipo de transicion de fase loquido-gel por aumento de la fuerza ionica.
AT86402170T ATE72990T1 (de) 1985-10-03 1986-10-02 Pharmazeutische zusammensetzung vom fluessig/gel- phasenuebergangstyp.
FI863990A FI91217C (fi) 1985-10-03 1986-10-02 Farmaseuttisen tai diagnostisen aineen oftalmologinen kantoainekoostumus
DE8686402170T DE3684121D1 (de) 1985-10-03 1986-10-02 Pharmazeutische zusammensetzung vom fluessig/gel-phasenuebergangstyp.
CA000519753A CA1280367C (fr) 1985-10-03 1986-10-03 Composition pharmaceutique du type subissant une transition de phase liquide-gel
HK42594A HK42594A (en) 1985-10-03 1994-05-05 Pharmaceutical composition of the type which undergoes liquid-gel phase transition
NO1995003C NO1995003I1 (no) 1985-10-03 1995-04-10 Timololmaleat og gellangummi
NL950012C NL950012I1 (nl) 1985-10-03 1995-08-07 Farmaceutische samenstelling van het type dat een vloeistof-gelfase-overgang ondergaat.
LV950262A LV5725B4 (lv) 1985-10-03 1995-08-29 Gelu veidojosa oftalmologiska kompozicija
CY177995A CY1779A (en) 1985-10-03 1995-10-20 Pharmaceutical composition of the type which undergoes liquid-gel phase transition

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8514689A FR2588189B1 (fr) 1985-10-03 1985-10-03 Composition pharmaceutique de type a transition de phase liquide-gel

Publications (2)

Publication Number Publication Date
FR2588189A1 FR2588189A1 (fr) 1987-04-10
FR2588189B1 true FR2588189B1 (fr) 1988-12-02

Family

ID=9323509

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8514689A Expired FR2588189B1 (fr) 1985-10-03 1985-10-03 Composition pharmaceutique de type a transition de phase liquide-gel

Country Status (25)

Country Link
US (1) US4861760A (fr)
EP (1) EP0227494B1 (fr)
JP (1) JPH0667853B2 (fr)
KR (1) KR940000229B1 (fr)
CN (1) CN1046094C (fr)
AT (1) ATE72990T1 (fr)
AU (1) AU595240B2 (fr)
CA (1) CA1280367C (fr)
CY (1) CY1779A (fr)
DE (2) DE3684121D1 (fr)
DK (1) DK170500B1 (fr)
ES (1) ES2002401A6 (fr)
FI (1) FI91217C (fr)
FR (1) FR2588189B1 (fr)
GR (1) GR862444B (fr)
HK (1) HK42594A (fr)
IE (1) IE59464B1 (fr)
IL (1) IL80156A (fr)
LU (1) LU88694I2 (fr)
LV (1) LV5725B4 (fr)
NL (1) NL950012I1 (fr)
NO (2) NO173212C (fr)
NZ (1) NZ217662A (fr)
PT (1) PT83471B (fr)
ZA (1) ZA867464B (fr)

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DK469886A (da) 1987-04-04
PT83471B (pt) 1988-11-30
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IL80156A (en) 1990-09-17
CN1046094C (zh) 1999-11-03
CN86106637A (zh) 1987-04-08
EP0227494B1 (fr) 1992-03-04
CY1779A (en) 1995-10-20
CA1280367C (fr) 1991-02-19
DE227494T1 (de) 1988-03-17
KR870003773A (ko) 1987-05-04
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ATE72990T1 (de) 1992-03-15
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US4861760A (en) 1989-08-29
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FI863990A0 (fi) 1986-10-02
FI863990L (fi) 1987-04-04
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EP0227494A1 (fr) 1987-07-01
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PT83471A (en) 1986-11-01
DK469886D0 (da) 1986-10-02
IE862481L (en) 1987-04-03
AU6318986A (en) 1987-04-09
AU595240B2 (en) 1990-03-29
LV5725B4 (lv) 1996-06-20

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