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FR2434393A1 - DEVICE AND METHOD FOR DETERMINING THE UREA CONTENT OF LIQUIDS - Google Patents

DEVICE AND METHOD FOR DETERMINING THE UREA CONTENT OF LIQUIDS

Info

Publication number
FR2434393A1
FR2434393A1 FR7915281A FR7915281A FR2434393A1 FR 2434393 A1 FR2434393 A1 FR 2434393A1 FR 7915281 A FR7915281 A FR 7915281A FR 7915281 A FR7915281 A FR 7915281A FR 2434393 A1 FR2434393 A1 FR 2434393A1
Authority
FR
France
Prior art keywords
liquids
urea
reagents
determining
serum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7915281A
Other languages
French (fr)
Other versions
FR2434393B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/039,113 external-priority patent/US4215995A/en
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of FR2434393A1 publication Critical patent/FR2434393A1/en
Application granted granted Critical
Publication of FR2434393B1 publication Critical patent/FR2434393B1/fr
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/62—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving urea
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N31/00—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods
    • G01N31/22—Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroup; Apparatus specially adapted for such methods using chemical indicators

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Abstract

L'invention concerne le dosage de l'urée dans des liquides. Le dispositif d'essai utilisé est obtenu par application en trois étapes de réactifs séparés l'un de l'autre sur une matrice de support modifiée par un acide. L'un des réactifs est le ophtalaldéhyde et l'autre est choisi entre la 3-hydroxy-1,2,3,4-tétrahydrobenzo-Øhõ-quinoléine, la 3-acétoxy-1,2,3,4-tétrahydrobenzo-Øhõ-quinoléine et leurs dichlorhydrates. Application au dosage de l'urée dans des liquides tels que le sérum sanguin, le plasma, l'urine et le liquide céphalorachidien, ainsi que dans des liquides industriels. Les réactifs sont stables et la précipitation, par exemple des protéines du sérum, est évitée. En outre, la couleur gênante due à la présence de bilirubine est minimisée lorsqu'on détermine la teneur en urée d'un sérum.The invention relates to the determination of urea in liquids. The test device used is obtained by the application in three steps of reagents separated from each other on an acid-modified support matrix. One of the reagents is ophthalaldehyde and the other is selected from 3-hydroxy-1,2,3,4-tetrahydrobenzo-Øhõ-quinoline, 3-acetoxy-1,2,3,4-tetrahydrobenzo-Øhõ -quinoline and their dihydrochlorides. Application to the determination of urea in liquids such as blood serum, plasma, urine and cerebrospinal fluid, as well as in industrial liquids. The reagents are stable and precipitation, for example of serum proteins, is avoided. In addition, bothersome color due to the presence of bilirubin is minimized when determining the urea content of a serum.

FR7915281A 1978-06-15 1979-06-14 DEVICE AND METHOD FOR DETERMINING THE UREA CONTENT OF LIQUIDS Granted FR2434393A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91558778A 1978-06-15 1978-06-15
US06/039,113 US4215995A (en) 1979-05-15 1979-05-15 Test means and assay for determining the urea content of fluids

Publications (2)

Publication Number Publication Date
FR2434393A1 true FR2434393A1 (en) 1980-03-21
FR2434393B1 FR2434393B1 (en) 1984-03-16

Family

ID=26715824

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7915281A Granted FR2434393A1 (en) 1978-06-15 1979-06-14 DEVICE AND METHOD FOR DETERMINING THE UREA CONTENT OF LIQUIDS

Country Status (9)

Country Link
AU (1) AU521386B2 (en)
CA (1) CA1108514A (en)
DE (1) DE2922748C2 (en)
ES (1) ES481516A1 (en)
FR (1) FR2434393A1 (en)
GB (1) GB2023815B (en)
IT (1) IT1116892B (en)
NL (1) NL187995C (en)
SE (1) SE444085B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1219848B (en) * 1988-03-03 1990-05-24 Miles Italiana COMPOUND INDICATORS, METHOD FOR THEIR PREPARATION AND USE IN A STEEL SYSTEM ASSAY SYSTEM
US8206944B2 (en) * 2006-01-19 2012-06-26 Lattec I/S Dry stick device construction and method for determining an analyte in a sample using said dry stick device
PL1982183T3 (en) * 2006-01-19 2012-11-30 Lattec I/S Dry stick device and method for determining an analyte in a sample

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3212855A (en) * 1962-08-06 1965-10-19 Miles Lab Diagnostic device
US3449080A (en) * 1964-10-29 1969-06-10 Johnson & Johnson Device for determining sodium or chloride concentration in body fluids
US3723064A (en) * 1971-07-26 1973-03-27 L Liotta Method and device for determining the concentration of a material in a liquid
US3890099A (en) * 1974-07-05 1975-06-17 David H Jung Colorimetric assay for urea
US3901657A (en) * 1974-04-29 1975-08-26 Sun Scient Inc Device for testing solutions and body fluids
FR2280897A1 (en) * 1974-07-30 1976-02-27 Boehringer Mannheim Gmbh STABLE TEST TAPES FOR THE DETECTION OF LIQUID CONSTITUENTS
FR2370978A1 (en) * 1976-11-10 1978-06-09 American Monitor Corp UREA DETERMINATION PROCESS

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3212855A (en) * 1962-08-06 1965-10-19 Miles Lab Diagnostic device
US3449080A (en) * 1964-10-29 1969-06-10 Johnson & Johnson Device for determining sodium or chloride concentration in body fluids
US3723064A (en) * 1971-07-26 1973-03-27 L Liotta Method and device for determining the concentration of a material in a liquid
US3901657A (en) * 1974-04-29 1975-08-26 Sun Scient Inc Device for testing solutions and body fluids
US3890099A (en) * 1974-07-05 1975-06-17 David H Jung Colorimetric assay for urea
FR2280897A1 (en) * 1974-07-30 1976-02-27 Boehringer Mannheim Gmbh STABLE TEST TAPES FOR THE DETECTION OF LIQUID CONSTITUENTS
FR2370978A1 (en) * 1976-11-10 1978-06-09 American Monitor Corp UREA DETERMINATION PROCESS

Also Published As

Publication number Publication date
IT1116892B (en) 1986-02-10
DE2922748C2 (en) 1984-03-22
NL187995B (en) 1991-10-01
SE444085B (en) 1986-03-17
GB2023815A (en) 1980-01-03
AU521386B2 (en) 1982-04-01
DE2922748A1 (en) 1979-12-20
CA1108514A (en) 1981-09-08
AU4786579A (en) 1980-11-20
NL7904720A (en) 1979-12-18
FR2434393B1 (en) 1984-03-16
SE7905266L (en) 1979-12-16
GB2023815B (en) 1982-12-15
NL187995C (en) 1992-03-02
IT7949382A0 (en) 1979-06-12
ES481516A1 (en) 1980-01-16

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Legal Events

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