FR2359110A1 - Derives de l'acide salicylique, leur obtention et compositions pharmaceutiques les contenant - Google Patents
Derives de l'acide salicylique, leur obtention et compositions pharmaceutiques les contenantInfo
- Publication number
- FR2359110A1 FR2359110A1 FR7722248A FR7722248A FR2359110A1 FR 2359110 A1 FR2359110 A1 FR 2359110A1 FR 7722248 A FR7722248 A FR 7722248A FR 7722248 A FR7722248 A FR 7722248A FR 2359110 A1 FR2359110 A1 FR 2359110A1
- Authority
- FR
- France
- Prior art keywords
- alkyl
- analgesic
- gastric irritation
- salicylic acid
- antiinflammatory
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 206010053155 Epigastric discomfort Diseases 0.000 title abstract 3
- 230000000202 analgesic effect Effects 0.000 title abstract 2
- 230000003110 anti-inflammatory effect Effects 0.000 title abstract 2
- 230000001754 anti-pyretic effect Effects 0.000 title abstract 2
- YGSDEFSMJLZEOE-UHFFFAOYSA-N Salicylic acid Natural products OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 title 1
- FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 title 1
- 229960004889 salicylic acid Drugs 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 abstract 3
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 abstract 2
- 229960001138 acetylsalicylic acid Drugs 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 2
- OBHAZAYREBSKKS-UHFFFAOYSA-N 2,2-dimethylpropanoyloxymethyl 2-hydroxybenzoate Chemical compound CC(C)(C)C(=O)OCOC(=O)C1=CC=CC=C1O OBHAZAYREBSKKS-UHFFFAOYSA-N 0.000 abstract 1
- JCXJVPUVTGWSNB-UHFFFAOYSA-N Nitrogen dioxide Chemical compound O=[N]=O JCXJVPUVTGWSNB-UHFFFAOYSA-N 0.000 abstract 1
- 125000000738 acetamido group Chemical group [H]C([H])([H])C(=O)N([H])[*] 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- GGRHYQCXXYLUTL-UHFFFAOYSA-N chloromethyl 2,2-dimethylpropanoate Chemical compound CC(C)(C)C(=O)OCCl GGRHYQCXXYLUTL-UHFFFAOYSA-N 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 229960001860 salicylate Drugs 0.000 abstract 1
- YGSDEFSMJLZEOE-UHFFFAOYSA-M salicylate Chemical compound OC1=CC=CC=C1C([O-])=O YGSDEFSMJLZEOE-UHFFFAOYSA-M 0.000 abstract 1
- 150000003902 salicylic acid esters Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
L'invention décrit l'obtention de nouveaux dérivés de l'acide salicylique. Ils ont pour formule :
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70716976A | 1976-07-21 | 1976-07-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2359110A1 true FR2359110A1 (fr) | 1978-02-17 |
Family
ID=24840632
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7722248A Withdrawn FR2359110A1 (fr) | 1976-07-21 | 1977-07-20 | Derives de l'acide salicylique, leur obtention et compositions pharmaceutiques les contenant |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JPS5331640A (fr) |
| DE (1) | DE2732144A1 (fr) |
| FR (1) | FR2359110A1 (fr) |
| IL (1) | IL52494A0 (fr) |
| SE (1) | SE7708340L (fr) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0002872A1 (fr) * | 1977-12-23 | 1979-07-11 | THE PROCTER & GAMBLE COMPANY | Procédé de préparation d'esters acylés d'hydroxy-carboxylates |
| WO2009049961A3 (fr) * | 2007-10-19 | 2009-06-25 | Nicox Sa | Nouveaux dérivés d'aspirine donneurs no |
| WO2010118968A1 (fr) * | 2009-04-16 | 2010-10-21 | Nicox S.A. | Dérivés d'aspirine donneurs de no |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2518922A (en) * | 1946-06-19 | 1950-08-15 | Monsanto Chemicals | Salicylic acid derivatives and method for making same |
-
1977
- 1977-07-08 IL IL52494A patent/IL52494A0/xx unknown
- 1977-07-15 DE DE19772732144 patent/DE2732144A1/de active Pending
- 1977-07-18 JP JP8596277A patent/JPS5331640A/ja active Pending
- 1977-07-19 SE SE7708340A patent/SE7708340L/xx unknown
- 1977-07-20 FR FR7722248A patent/FR2359110A1/fr not_active Withdrawn
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2518922A (en) * | 1946-06-19 | 1950-08-15 | Monsanto Chemicals | Salicylic acid derivatives and method for making same |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0002872A1 (fr) * | 1977-12-23 | 1979-07-11 | THE PROCTER & GAMBLE COMPANY | Procédé de préparation d'esters acylés d'hydroxy-carboxylates |
| WO2009049961A3 (fr) * | 2007-10-19 | 2009-06-25 | Nicox Sa | Nouveaux dérivés d'aspirine donneurs no |
| WO2010118968A1 (fr) * | 2009-04-16 | 2010-10-21 | Nicox S.A. | Dérivés d'aspirine donneurs de no |
Also Published As
| Publication number | Publication date |
|---|---|
| IL52494A0 (en) | 1977-10-31 |
| DE2732144A1 (de) | 1978-02-02 |
| JPS5331640A (en) | 1978-03-25 |
| SE7708340L (sv) | 1978-01-22 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES487957A0 (es) | Equipo para dialisis peritoneales ambulatorias continuas | |
| SE426501B (sv) | Beleggningskomposition baserad pa fluorkolpolymer innehallande alkalimetallsilikat, ett salt av en polyamidsyra och glimmerpartiklar samt anvendning av beleggningskompositionen | |
| ES229946Y (es) | Pieza de union perfeccionada para el acoplamiento de bloquesde construccion de jugueteria. | |
| FR2359110A1 (fr) | Derives de l'acide salicylique, leur obtention et compositions pharmaceutiques les contenant | |
| NL980021I2 (nl) | Organische amine fosfonzuur complexen voor de behandeling van calcifieke tumoren. | |
| KR950700281A (ko) | 퀴놀론카르복실산 유도체 수화물 결정(crystal of quinolonecarboxylic acid derivative hydrate) | |
| GB1290818A (fr) | ||
| BR7901244A (pt) | Escada rolante com dispositivo de arrasto para a conducao conjunta de carros de transporte | |
| SE8206984L (sv) | Terapeutiskt medel | |
| FI911778A7 (fi) | Difluoriglutamiinihappo-konjugaatit folaattien ja antifolaattien kanssa neoplastisten sairauksien hoitoon | |
| AU8655182A (en) | Benzopyran-6-yl ethane-carboxylic acid and derivatives | |
| ES455708A2 (es) | Un procedimiento para elevar la tolerancia intravenosa de globulinas gamma precipitadas de la sangre o de productos sanguineos. | |
| ES8307791A1 (es) | "procedimiento para preparar derivados de nicotinoilbenzoguanamina". | |
| GB1374320A (en) | Triazine derivatives | |
| ES464553A2 (es) | Mejoras introducidas en el objeto de la patente principal por procedimiento para la preparacion de anilidas de acido 5-metil-isoxazol-4-carboxilico. | |
| DK534283A (da) | Fremgangsmaade til fremstilling af acetylsalicylsyrederivater | |
| FR2378783A2 (fr) | Nouveaux acides thieno (2,3-b) thienyl carbonylphenylalcanoiques, leur preparation et les compositions qui les contiennent | |
| IE33045L (en) | Amine salts of cephalosporins | |
| FR2215217A1 (en) | Ortho thymotic acid di alkyl amines - coronary dilators, anti arrhythmic agents, local anaesthetics and antitussives | |
| FR2198735A1 (en) | Substd 3-alkyl 2-nitrobenzofurans - by nitration of corresp 2-acyl derivs, used as parasiticides | |
| FR2372816A1 (fr) | Benzisothiazolones et medicaments contenant ces substances | |
| BE855325A (fr) | Procede de preparation de l'acide 6-(d-2-phenyl-2-(4-pyridylformimidoylaminoacetamido)-acetamido)-penicillanique | |
| DK534383A (da) | Fremgangsmaade til fremstilling af acetylsalicylsyrederivater | |
| JPS5285187A (en) | Antibacterials against pseudomonas aeruginosa | |
| IT1221033B (it) | Indoli sostituiti e loro procedimento di separazione |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |