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FR2238491B1 - - Google Patents

Info

Publication number
FR2238491B1
FR2238491B1 FR7426130A FR7426130A FR2238491B1 FR 2238491 B1 FR2238491 B1 FR 2238491B1 FR 7426130 A FR7426130 A FR 7426130A FR 7426130 A FR7426130 A FR 7426130A FR 2238491 B1 FR2238491 B1 FR 2238491B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7426130A
Other languages
French (fr)
Other versions
FR2238491A1 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ER Squibb and Sons LLC
Original Assignee
ER Squibb and Sons LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ER Squibb and Sons LLC filed Critical ER Squibb and Sons LLC
Publication of FR2238491A1 publication Critical patent/FR2238491A1/fr
Application granted granted Critical
Publication of FR2238491B1 publication Critical patent/FR2238491B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/01Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton
    • C07C323/09Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and halogen atoms, or nitro or nitroso groups bound to the same carbon skeleton having sulfur atoms of thio groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/64Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton
    • C07C323/66Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and sulfur atoms, not being part of thio groups, bound to the same carbon skeleton containing sulfur atoms of sulfo, esterified sulfo or halosulfonyl groups, bound to the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32One oxygen, sulfur or nitrogen atom
    • C07D239/42One nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FR7426130A 1973-07-26 1974-07-26 Expired FR2238491B1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US382802A US3875162A (en) 1973-07-26 1973-07-26 Certain 6H-pyrimido{8 1,2-c{9 {8 1,3,5{9 benzothiadiaza compounds

Publications (2)

Publication Number Publication Date
FR2238491A1 FR2238491A1 (de) 1975-02-21
FR2238491B1 true FR2238491B1 (de) 1978-07-28

Family

ID=23510466

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7426130A Expired FR2238491B1 (de) 1973-07-26 1974-07-26

Country Status (6)

Country Link
US (1) US3875162A (de)
JP (1) JPS5041892A (de)
CA (1) CA1051429A (de)
DE (1) DE2435382A1 (de)
FR (1) FR2238491B1 (de)
GB (1) GB1476684A (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3966733A (en) * 1973-07-26 1976-06-29 E. R. Squibb & Sons, Inc. Intermediates for certain benzothiadiazepine and benzothiadiazocine compounds
CN105175434A (zh) 2009-02-05 2015-12-23 伊缪诺金公司 新型苯并二氮杂*衍生物
WO2012128868A1 (en) 2011-02-15 2012-09-27 Immunogen, Inc. Cytotoxic benzodiazepine derivatives
WO2014031566A1 (en) 2012-08-22 2014-02-27 Immunogen, Inc. Cytotoxic benzodiazepine derivatives
KR102632830B1 (ko) 2014-09-03 2024-02-02 이뮤노젠 아이엔씨 세포독성 벤조다이아제핀 유도체
US9381256B2 (en) 2014-09-03 2016-07-05 Immunogen, Inc. Cytotoxic benzodiazepine derivatives
MA51510A (fr) 2017-04-20 2020-11-11 Immunogen Inc Procédés de préparation de dérivés d'indolinobenzodiazépine
TW201839001A (zh) 2017-04-20 2018-11-01 美商伊繆諾金公司 細胞毒性苯并二氮平衍生物及其綴合物
WO2019133652A1 (en) 2017-12-28 2019-07-04 Immunogen, Inc. Benzodiazepine derivatives
EP3947395A1 (de) 2019-03-29 2022-02-09 ImmunoGen, Inc. Zytotoxische bis-benzodiazepinderivate und konjugate davon mit zellbindenden mitteln zur hemmung von abnormalem zellwachstum oder zur behandlung von proliferativen krankheiten

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH530412A (de) * 1968-07-15 1972-11-15 Ciba Geigy Ag Verfahren zur Herstellung von (1)Benzothieno-(2,3-d)pyrimidinen
GB1275804A (en) * 1969-07-03 1972-05-24 Seperic Improvements in or relating to new sulphur containing derivatives of pyrimidine, their preparation and their applications
US3704303A (en) * 1971-03-17 1972-11-28 American Home Prod 6,7,8,9 - tetrahydropyrimido(2,1-b) - benzothiazole-6-carboxylic acid,alkyl esters

Also Published As

Publication number Publication date
DE2435382A1 (de) 1975-02-13
CA1051429A (en) 1979-03-27
GB1476684A (en) 1977-06-16
FR2238491A1 (de) 1975-02-21
US3875162A (en) 1975-04-01
JPS5041892A (de) 1975-04-16

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Legal Events

Date Code Title Description
ST Notification of lapse