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FI98147B - Menetelmä terapeuttisesti käyttökelpoisten BU-3608-antibioottien seriinianalogien valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisten BU-3608-antibioottien seriinianalogien valmistamiseksi

Info

Publication number
FI98147B
FI98147B FI895281A FI895281A FI98147B FI 98147 B FI98147 B FI 98147B FI 895281 A FI895281 A FI 895281A FI 895281 A FI895281 A FI 895281A FI 98147 B FI98147 B FI 98147B
Authority
FI
Finland
Prior art keywords
antibiotics
preparation
therapeutically useful
serine
analogues
Prior art date
Application number
FI895281A
Other languages
English (en)
Swedish (sv)
Other versions
FI98147C (fi
FI895281A0 (fi
Inventor
Yosuke Sawada
Masatoshi Kakushima
Maki Nishio
Takeo Miyaki
Toshikazu Oki
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of FI895281A0 publication Critical patent/FI895281A0/fi
Application granted granted Critical
Publication of FI98147B publication Critical patent/FI98147B/fi
Publication of FI98147C publication Critical patent/FI98147C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P29/00—Preparation of compounds containing a naphthacene ring system, e.g. tetracycline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/244—Anthraquinone radicals, e.g. sennosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/56—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical directly bound to a condensed ring system having three or more carbocyclic rings, e.g. daunomycin, adriamycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
FI895281A 1988-11-10 1989-11-07 Menetelmä terapeuttisesti käyttökelpoisten BU-3608-antibioottien seriinianalogien valmistamiseksi FI98147C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26982188 1988-11-10
US07/269,821 US4973673A (en) 1988-11-10 1988-11-10 Serine analogs of BU-3608 antibiotics

Publications (3)

Publication Number Publication Date
FI895281A0 FI895281A0 (fi) 1989-11-07
FI98147B true FI98147B (fi) 1997-01-15
FI98147C FI98147C (fi) 1997-04-25

Family

ID=23028793

Family Applications (1)

Application Number Title Priority Date Filing Date
FI895281A FI98147C (fi) 1988-11-10 1989-11-07 Menetelmä terapeuttisesti käyttökelpoisten BU-3608-antibioottien seriinianalogien valmistamiseksi

Country Status (23)

Country Link
US (1) US4973673A (fi)
EP (1) EP0368349B1 (fi)
JP (1) JP2817064B2 (fi)
KR (1) KR930006995B1 (fi)
CN (1) CN1044299A (fi)
AT (1) ATE94556T1 (fi)
AU (1) AU628418B2 (fi)
CA (1) CA2001714C (fi)
CY (1) CY1884A (fi)
DE (1) DE68909170T2 (fi)
DK (1) DK173464B1 (fi)
EG (1) EG19153A (fi)
ES (1) ES2059681T3 (fi)
FI (1) FI98147C (fi)
HK (1) HK151595A (fi)
IE (1) IE63305B1 (fi)
IL (1) IL92240A (fi)
MY (1) MY110238A (fi)
NO (1) NO172393C (fi)
OA (1) OA09246A (fi)
PL (2) PL161784B1 (fi)
PT (1) PT92263B (fi)
ZA (1) ZA898566B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5109122A (en) * 1987-11-02 1992-04-28 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Antibiotics, dexylosylbenanomicin B
US5183808A (en) * 1988-11-10 1993-02-02 Bristol-Myers Squibb Company Method for treating fungal infections with serine analogs of BU-3608 antibiotics
US5061624A (en) * 1988-11-10 1991-10-29 Bristol-Myers Company Serine analogs of BU-3608 antibiotics
US5114857A (en) * 1988-11-10 1992-05-19 Bristol-Myers Company Actinomadura hibisca microorganism useful for preparing serine analogs of BU-3608 antibiotics
JP2643404B2 (ja) * 1989-01-13 1997-08-20 財団法人微生物化学研究会 新抗生物質ｎ―アセチルベナノマイシンｂならびにその製造法
FI92207C (fi) * 1989-11-14 1994-10-10 Squibb Bristol Myers Co Menetelmä terapeuttisesti käyttökelpoisten pradimisiinijohdannaisten valmistamiseksi
US5227370A (en) * 1989-11-14 1993-07-13 Bristol-Myers Squibb Company Pradimicin derivatives
CA2030166C (en) * 1989-11-22 1997-10-07 Shimpei Aburaki Pradimicin derivatives
JP3035313B2 (ja) * 1990-03-14 2000-04-24 財団法人微生物化学研究会 ベナノマイシンａ４▲′′′▼‐ｏ‐硫酸エステルの塩類およびそれらの製造法
US5843908A (en) * 1990-09-28 1998-12-01 Bristol-Myers Squibb Company Pradimicins l and fl, and derivatives thereof
US5696096A (en) * 1990-09-28 1997-12-09 Bristol-Myers Squibb Company Pradimicin derivatives
US5217877A (en) * 1990-09-28 1993-06-08 Bristol-Myers Squibb Company Process for the preparation of α-glucosidase inhibitor, pradimicin Q
CA2068484A1 (en) * 1991-05-29 1992-11-30 Osamu Tenmyo Pradimicin s antibiotics
US5194371A (en) * 1991-07-31 1993-03-16 Bristol-Myers Squibb Company Production of pradimicin antibiotics
JP3134010B2 (ja) * 1991-11-26 2001-02-13 財団法人微生物化学研究会 デスアラニンベナノマイシンａ誘導体およびそれらの製造法
US5837828A (en) * 1992-04-08 1998-11-17 Bristol-Myers Squibb Co. Pradimicin derivatives
US5420261A (en) * 1992-05-29 1995-05-30 Schering Corporation Glycosides of 3'-deoxyaquayamycin antibiotics
US5326867A (en) * 1992-07-16 1994-07-05 Bristol-Myers Squibb Company Pradimic acids, amides, and pradimicin derivatives
US5338728A (en) * 1992-08-14 1994-08-16 Bristol-Myers Squibb Pradimicin compounds
ZA938725B (en) * 1992-11-30 1994-05-23 Bristol Myers Squibb Co C-11 Modified pradimicin derivatives

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58154582A (ja) * 1982-03-10 1983-09-14 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体およびその製造法
US4870165A (en) * 1987-02-02 1989-09-26 Bristol-Myers Company Antifungal antibiotics

Also Published As

Publication number Publication date
AU4461589A (en) 1990-05-17
DK561289D0 (da) 1989-11-09
JP2817064B2 (ja) 1998-10-27
NO894417L (no) 1990-05-11
IE893617L (en) 1990-05-10
PL161784B1 (pl) 1993-07-30
EP0368349A2 (en) 1990-05-16
DE68909170D1 (de) 1993-10-21
JPH02188596A (ja) 1990-07-24
ZA898566B (en) 1990-10-31
FI98147C (fi) 1997-04-25
NO172393B (no) 1993-04-05
AU628418B2 (en) 1992-09-17
NO894417D0 (no) 1989-11-07
KR900008049A (ko) 1990-06-02
PL161779B1 (pl) 1993-07-30
ES2059681T3 (es) 1994-11-16
DK173464B1 (da) 2000-11-27
DK561289A (da) 1990-05-11
MY110238A (en) 1998-03-31
HK151595A (en) 1995-09-29
IE63305B1 (en) 1995-04-05
EG19153A (en) 1994-07-30
PT92263A (pt) 1990-05-31
DE68909170T2 (de) 1994-03-10
IL92240A (en) 1994-02-27
ATE94556T1 (de) 1993-10-15
US4973673A (en) 1990-11-27
CY1884A (en) 1996-04-05
IL92240A0 (en) 1990-07-26
PT92263B (pt) 1995-07-06
FI895281A0 (fi) 1989-11-07
NO172393C (no) 1993-07-14
CA2001714A1 (en) 1990-05-10
OA09246A (fr) 1992-06-30
CA2001714C (en) 1999-01-26
CN1044299A (zh) 1990-08-01
KR930006995B1 (ko) 1993-07-26
EP0368349B1 (en) 1993-09-15
EP0368349A3 (en) 1991-04-24

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Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed

Owner name: BRISTOL-MYERS SQUIBB COMPANY