FI980038L - Tuumorinekroositekijän alfa inhibiittoreita - Google Patents

Tuumorinekroositekijän alfa inhibiittoreita Download PDF

Info

Publication number: FI980038L
Authority: FI; Finland
Prior art keywords: necrosis factor; tumor necrosis; factor alpha; alpha inhibitors; inhibitors
Prior art date: 1995-08-29

Application number

FI980038A

Other languages

English (en)

Swedish (sv)

Other versions

FI980038A7 (fi

FI980038A0 (fi

Inventor

George W Mueller

Mary Shire

Original Assignee

Celgene Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-08-29

Filing date

1996-08-29

Publication date

1998-02-24

1996-08-29 Application filed by Celgene Corp filed Critical Celgene Corp

1998-01-09 Publication of FI980038A0 publication Critical patent/FI980038A0/fi

1998-02-24 Publication of FI980038A7 publication Critical patent/FI980038A7/fi

1998-02-24 Publication of FI980038L publication Critical patent/FI980038L/fi

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/4035—Isoindoles, e.g. phthalimide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Immunology (AREA)
Communicable Diseases (AREA)
Rheumatology (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Virology (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Physical Education & Sports Medicine (AREA)
Transplantation (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Cardiology (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

FI980038A 1995-08-29 1996-08-29 Tuumorinekroositekijän alfa inhibiittoreita FI980038L (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/520,710 US5728845A (en)	1995-08-29	1995-08-29	Immunotherapeutic nitriles
PCT/US1996/014077 WO1997008143A1 (en)	1995-08-29	1996-08-29	Inhibitors of tumor necrosis factor alpha

Publications (3)

Publication Number	Publication Date
FI980038A0 FI980038A0 (fi)	1998-01-09
FI980038A7 FI980038A7 (fi)	1998-02-24
FI980038L true FI980038L (fi)	1998-02-24

Family

ID=24073769

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI980038A FI980038L (fi)	1995-08-29	1996-08-29	Tuumorinekroositekijän alfa inhibiittoreita

Country Status (19)

Country	Link
US (3)	US5728845A (fi)
EP (3)	EP1367051A3 (fi)
JP (2)	JP2000500118A (fi)
KR (2)	KR100440874B1 (fi)
AT (1)	ATE259787T1 (fi)
AU (1)	AU716775B2 (fi)
CA (1)	CA2230487A1 (fi)
CZ (1)	CZ291613B6 (fi)
DE (1)	DE69631592T2 (fi)
DK (1)	DK0851857T3 (fi)
ES (1)	ES2216059T3 (fi)
FI (1)	FI980038L (fi)
HU (1)	HUP9901410A3 (fi)
NZ (1)	NZ318212A (fi)
PL (1)	PL329107A1 (fi)
PT (1)	PT851857E (fi)
RU (1)	RU2196134C2 (fi)
SK (1)	SK284144B6 (fi)
WO (1)	WO1997008143A1 (fi)

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US5463063A (en) *	1993-07-02	1995-10-31	Celgene Corporation	Ring closure of N-phthaloylglutamines
CA2227237C (en)	1995-07-26	2005-12-13	Pfizer Inc.	N-(aroyl)glycine hydroxamic acid derivatives and related compounds

1995
- 1995-08-29 US US08/520,710 patent/US5728845A/en not_active Expired - Fee Related
1996
- 1996-08-29 WO PCT/US1996/014077 patent/WO1997008143A1/en not_active Ceased
- 1996-08-29 KR KR10-1998-0701029A patent/KR100440874B1/ko not_active Expired - Fee Related
- 1996-08-29 SK SK272-98A patent/SK284144B6/sk unknown
- 1996-08-29 FI FI980038A patent/FI980038L/fi unknown
- 1996-08-29 PL PL96329107A patent/PL329107A1/xx unknown
- 1996-08-29 EP EP03077311A patent/EP1367051A3/en not_active Withdrawn
- 1996-08-29 EP EP96930664A patent/EP0851857B1/en not_active Expired - Lifetime
- 1996-08-29 NZ NZ318212A patent/NZ318212A/en unknown
- 1996-08-29 PT PT96930664T patent/PT851857E/pt unknown
- 1996-08-29 DK DK96930664T patent/DK0851857T3/da active
- 1996-08-29 CZ CZ1998609A patent/CZ291613B6/cs not_active IP Right Cessation
- 1996-08-29 HU HU9901410A patent/HUP9901410A3/hu unknown
- 1996-08-29 KR KR10-2003-7015515A patent/KR20030097902A/ko not_active Ceased
- 1996-08-29 JP JP9510629A patent/JP2000500118A/ja not_active Ceased
- 1996-08-29 DE DE69631592T patent/DE69631592T2/de not_active Expired - Fee Related
- 1996-08-29 RU RU98105689/04A patent/RU2196134C2/ru not_active IP Right Cessation
- 1996-08-29 AT AT96930664T patent/ATE259787T1/de not_active IP Right Cessation
- 1996-08-29 ES ES96930664T patent/ES2216059T3/es not_active Expired - Lifetime
- 1996-08-29 AU AU69632/96A patent/AU716775B2/en not_active Ceased
- 1996-08-29 CA CA002230487A patent/CA2230487A1/en not_active Abandoned
- 1996-08-29 EP EP99200946A patent/EP0957091B1/en not_active Expired - Lifetime
1998
- 1998-01-14 US US09/007,135 patent/US5968945A/en not_active Expired - Lifetime
1999
- 1999-06-11 US US09/330,701 patent/US6180644B1/en not_active Expired - Lifetime
2008
- 2008-02-25 JP JP2008043383A patent/JP2008133303A/ja active Pending

Also Published As

Publication number	Publication date
PL329107A1 (en)	1999-03-15
KR20030097902A (ko)	2003-12-31
FI980038A7 (fi)	1998-02-24
RU2196134C2 (ru)	2003-01-10
PT851857E (pt)	2004-07-30
CZ60998A3 (cs)	1998-07-15
EP0957091A1 (en)	1999-11-17
JP2000500118A (ja)	2000-01-11
EP0851857B1 (en)	2004-02-18
DE69631592T2 (de)	2004-12-16
CA2230487A1 (en)	1997-03-06
EP1367051A2 (en)	2003-12-03
AU6963296A (en)	1997-03-19
NZ318212A (en)	2001-05-25
HUP9901410A3 (en)	1999-11-29
ATE259787T1 (de)	2004-03-15
US5728845A (en)	1998-03-17
JP2008133303A (ja)	2008-06-12
US6180644B1 (en)	2001-01-30
WO1997008143A1 (en)	1997-03-06
EP0957091B1 (en)	2003-06-04
US5968945A (en)	1999-10-19
FI980038A0 (fi)	1998-01-09
EP0851857A1 (en)	1998-07-08
ES2216059T3 (es)	2004-10-16
DK0851857T3 (da)	2004-06-21
AU716775B2 (en)	2000-03-09
SK284144B6 (sk)	2004-10-05
CZ291613B6 (cs)	2003-04-16
KR19990036361A (ko)	1999-05-25
KR100440874B1 (ko)	2005-05-17
HK1022692A1 (en)	2000-08-18
HUP9901410A2 (hu)	1999-09-28
EP1367051A3 (en)	2003-12-17
SK27298A3 (en)	1998-07-08
DE69631592D1 (de)	2004-03-25

Publication	Publication Date	Title
FI980038L (fi)	1998-02-24	Tuumorinekroositekijän alfa inhibiittoreita
EP0715619A4 (en)	1997-03-19	Inhibitors of tnf-alpha secretion
NO941142D0 (no)	1994-03-28	Tumor-nekrosefaktormuteiner
DE69600784D1 (de)	1998-11-19	Proteinkinase-C-Inhibitor
FI963597A7 (fi)	1996-11-14	Isoprenyylitransferaasi-inhibiittoreita
NO972930D0 (no)	1997-06-23	Fibronectin-adhesjonsinhibitorer
DE69414482D1 (de)	1998-12-17	Tumorgewebe - Charakterisierungs-Instrument
NO942064D0 (no)	1994-06-03	yminhibitorer
FI945706A7 (fi)	1995-06-08	Proteiinikinaasi C-inhibiittoreita
FI972160A0 (fi)	1997-05-21	Matriisimetalloproteaasi-inhibiittorit
DK1004669T3 (da)	2007-08-27	Hidtil ukendte differentieringsinhibitor
ID19198A (id)	1998-06-28	Inhibitor metaloprotease heterosiklik
FI941767L (fi)	1994-10-17	1H-indoli-3-asetamidi sPLA2 inhibiittoreita
LV12150A (lv)	1998-10-20	Farneziltransferazes inhibitori
ID18416A (id)	1998-04-09	Inhibitor metaloprotease diheterosiklik
NO20002121D0 (no)	2000-04-26	Benzotiazol-protein-tyrosin-kinaseinhibitorer
DE69435267D1 (de)	2010-03-18	Proteinkinase C Inhibitoren
DE59703982D1 (de)	2001-08-16	Zielscheibenanordnung
DK1027332T3 (da)	2004-10-04	Hidtil ukendte lactametalloproteaseinhibitorer
DK0958287T3 (da)	2003-01-20	Sulfamidmetalloprotease-inhibitorer
FI971784L (fi)	1997-04-25	Apolipoproteiini B-synteesin estäjiä
ID18417A (id)	1998-04-09	Inhibitor ditentat metaloprotease
DE69323185D1 (de)	1999-03-04	Proteinkinase c-inhibitor
DE69736109D1 (de)	2006-07-27	Differenzierungsinhibitor
ID17792A (id)	1998-01-29	Penghambat penghambat metaloproreinase matriks