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FI970833L - Dihydro-2,3-bentsodiatsepiinijohdannaiset - Google Patents

Dihydro-2,3-bentsodiatsepiinijohdannaiset Download PDF

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Publication number
FI970833L
FI970833L FI970833A FI970833A FI970833L FI 970833 L FI970833 L FI 970833L FI 970833 A FI970833 A FI 970833A FI 970833 A FI970833 A FI 970833A FI 970833 L FI970833 L FI 970833L
Authority
FI
Finland
Prior art keywords
dihydro
benzodiazepine derivatives
benzodiazepine
derivatives
Prior art date
Application number
FI970833A
Other languages
English (en)
Swedish (sv)
Other versions
FI970833A0 (fi
FI113049B (fi
Inventor
Benjamin Alan Anderson
Marvin Martin Hansen
Nancy Kay Harn
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI970833A0 publication Critical patent/FI970833A0/fi
Publication of FI970833L publication Critical patent/FI970833L/fi
Application granted granted Critical
Publication of FI113049B publication Critical patent/FI113049B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI970833A 1994-08-31 1997-02-27 (R)-7-(aryylisubstituoitu)-8,9-dihydro-8-alkyyli-5-(4-aminofenyyli)-7-H-1,3-dioksolo[4,5-h] [2,3]bentsodiatsepiini- tai (R)-7-(aryylisubstituoitu)-8,9-dihydro-8-alkyyli-5-(4-nitrofenyyli)-7-H-1,3-dioksolo [4,5-h] [2,3] -bentsodiatsepiiniyhdiste FI113049B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US29864594A 1994-08-31 1994-08-31
US29864594 1994-08-31
US41302995A 1995-03-28 1995-03-28
US41302995 1995-03-28
US9510945 1995-08-30
PCT/US1995/010945 WO1996006606A1 (en) 1994-08-31 1995-08-30 Dihydro-2,3-benzodiazepine derivatives

Publications (3)

Publication Number Publication Date
FI970833A0 FI970833A0 (fi) 1997-02-27
FI970833L true FI970833L (fi) 1997-02-27
FI113049B FI113049B (fi) 2004-02-27

Family

ID=26970798

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970833A FI113049B (fi) 1994-08-31 1997-02-27 (R)-7-(aryylisubstituoitu)-8,9-dihydro-8-alkyyli-5-(4-aminofenyyli)-7-H-1,3-dioksolo[4,5-h] [2,3]bentsodiatsepiini- tai (R)-7-(aryylisubstituoitu)-8,9-dihydro-8-alkyyli-5-(4-nitrofenyyli)-7-H-1,3-dioksolo [4,5-h] [2,3] -bentsodiatsepiiniyhdiste

Country Status (12)

Country Link
US (1) US5795886A (fi)
EP (3) EP1593683A3 (fi)
JP (1) JP4131987B2 (fi)
AT (2) ATE212994T1 (fi)
CA (1) CA2198751C (fi)
DE (2) DE69534407T2 (fi)
DK (2) DK0771198T3 (fi)
ES (2) ES2244524T3 (fi)
FI (1) FI113049B (fi)
NZ (1) NZ292417A (fi)
PT (2) PT1157992E (fi)
WO (1) WO1996006606A1 (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA972746B (en) * 1996-04-04 1998-10-09 Egyt Gyogyszervegyeszeti Gyar Novel 2,3-benzodiazepine derivatives
HUP9701325A1 (hu) * 1997-07-31 2000-08-28 Gyógyszerkutató Intézet Kft. Új 2,3-benzodiazepin-származékok
HU9803014D0 (en) * 1998-12-23 1999-02-01 Egyt Gyogyszervegyeszeti Gyar Novel phtalazine derivatives, process for their production and pharmaceutical compositions containing the same
HU227128B1 (en) * 1999-07-07 2010-07-28 Egyt Gyogyszervegyeszeti Gyar New 2,3-benzodiazepine derivatives
US6649607B2 (en) * 2001-05-18 2003-11-18 Vela Pharmaceuticals, Inc. Compositions and methods for treating or preventing convulsions or seizures
US6858605B2 (en) * 2003-02-04 2005-02-22 Ivax Drug Research Institute, Ltd. Substituted 2,3-benzodiazepine derivatives
TW200902024A (en) * 2007-04-02 2009-01-16 Teva Pharma Novel 2,3-benzodiazepine derivatives and their use as antipsychotic agents
CU20090172A7 (es) 2009-10-09 2011-10-05 Ct De Investigación Y Desarrollo De Medicamentos Sistemas tricíclicos y tetracíclicos con actividad sobre el sistema nervioso central y vascular

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU206719B (en) * 1990-12-21 1992-12-28 Gyogyszerkutato Intezet Process for producing 1-/4-acylamino-phenyl/-7,8-methylenedioxy-5h-2,3-benzodiazepine derivatives, acid addicional salts and pharmaceutical compositions containing them
HU219778B (hu) * 1990-12-21 2001-07-30 Gyógyszerkutató Intézet Közös Vállalat Eljárás N-acil-2,3-benzodiazepin-származékok, savaddíciós sóik és az ezeket tartalmazó gyógyászati készítmények előállítására, valamint a vegyületek egy csoportja, és az ezeket tartalmazó gyógyászati készítmények
HU219777B (hu) * 1993-07-02 2001-07-30 Gyógyszerkutató Intézet Kft. Optikailag aktív 1-(4-nitro-fenil)-4-metil-7,8-metiléndioxi-3,4-dihidro-5H-2,3-benzodiazepin és eljárás előállítására

Also Published As

Publication number Publication date
DE69534407D1 (de) 2005-09-29
EP1157992B1 (en) 2005-08-24
ATE302779T1 (de) 2005-09-15
FI970833A0 (fi) 1997-02-27
CA2198751A1 (en) 1996-03-07
DK1157992T3 (da) 2005-10-24
EP0771198A4 (fi) 1997-05-28
EP1157992A1 (en) 2001-11-28
PT1157992E (pt) 2005-10-31
HK1013794A1 (en) 1999-09-10
US5795886A (en) 1998-08-18
DK0771198T3 (da) 2002-04-22
WO1996006606A1 (en) 1996-03-07
FI113049B (fi) 2004-02-27
EP0771198B1 (en) 2002-02-06
PT771198E (pt) 2002-06-28
AU3418695A (en) 1996-03-22
EP1593683A3 (en) 2006-10-25
AU689639B2 (en) 1998-04-02
DE69534407T2 (de) 2006-03-16
JP4131987B2 (ja) 2008-08-13
DE69525342D1 (de) 2002-03-21
JPH10505066A (ja) 1998-05-19
ATE212994T1 (de) 2002-02-15
DE69525342T2 (de) 2002-11-07
CA2198751C (en) 2006-07-11
ES2244524T3 (es) 2005-12-16
EP0771198A1 (en) 1997-05-07
EP1593683A2 (en) 2005-11-09
ES2170804T3 (es) 2002-08-16
NZ292417A (en) 1998-09-24

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