[go: up one dir, main page]

FI970696L - Oligonucleotide conjugates, compositions and methods for degrading ribonucleic acids - Google Patents

Oligonucleotide conjugates, compositions and methods for degrading ribonucleic acids Download PDF

Info

Publication number
FI970696L
FI970696L FI970696A FI970696A FI970696L FI 970696 L FI970696 L FI 970696L FI 970696 A FI970696 A FI 970696A FI 970696 A FI970696 A FI 970696A FI 970696 L FI970696 L FI 970696L
Authority
FI
Finland
Prior art keywords
compositions
methods
ribonucleic acids
oligonucleotide conjugates
degrading
Prior art date
Application number
FI970696A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI970696A0 (en
FI970696A7 (en
Inventor
Dieter Huesken
Heinz Moser
Robert Haener
Jonathan Hall
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI970696L publication Critical patent/FI970696L/en
Publication of FI970696A0 publication Critical patent/FI970696A0/en
Publication of FI970696A7 publication Critical patent/FI970696A7/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0042Photocleavage of drugs in vivo, e.g. cleavage of photolabile linkers in vivo by UV radiation for releasing the pharmacologically-active agent from the administered agent; photothrombosis or photoocclusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FI970696A 1994-09-02 1995-08-30 Oligonucleotide conjugates, compositions and methods for degrading ribonucleic acids FI970696A7 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH269494 1994-09-02
PCT/EP1995/003408 WO1996007667A1 (en) 1994-09-02 1995-08-30 Oligonucleotide conjugates, compositions and methods for splitting ribonucleic acids

Publications (3)

Publication Number Publication Date
FI970696L true FI970696L (en) 1997-02-19
FI970696A0 FI970696A0 (en) 1997-02-19
FI970696A7 FI970696A7 (en) 1997-02-19

Family

ID=4239485

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970696A FI970696A7 (en) 1994-09-02 1995-08-30 Oligonucleotide conjugates, compositions and methods for degrading ribonucleic acids

Country Status (8)

Country Link
EP (1) EP0778845A1 (en)
JP (1) JPH10505353A (en)
AU (1) AU3519095A (en)
CA (1) CA2197785A1 (en)
FI (1) FI970696A7 (en)
HU (1) HUT77034A (en)
NO (1) NO970885L (en)
WO (1) WO1996007667A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5798491A (en) * 1993-06-09 1998-08-25 Board Of Regents, The University Of Texas System Multi-mechanistic chemical cleavage using certain metal complexes
US5714328A (en) * 1995-06-07 1998-02-03 Board Of Regents, The University Of Texas System RNA photocleavage using texaphyrins
DE69720469T2 (en) * 1996-08-20 2004-05-06 Pharmacyclics, Inc., Sunnyvale NUCLEIC ACIDS DERIVATIVELY DERIVATIZED WITH A TEXAPHYRINE METAL COMPLEX AND THEIR USE
US6022959A (en) * 1996-08-20 2000-02-08 Pharmacyclics, Inc. Nucleic acids internally-derivatized with a texaphyrin metal complex and uses thereof
US6255476B1 (en) * 1999-02-22 2001-07-03 Pe Corporation (Ny) Methods and compositions for synthesis of labelled oligonucleotides and analogs on solid-supports
KR101040700B1 (en) * 2006-11-16 2011-06-10 주식회사 엘지화학 Purification method of terephthalaldehyde
PA8775701A1 (en) 2007-04-06 2009-04-23 Neurocrine Biosciences Inc ANTAGONIST OF THE RECEIVERS OF THE GONADOTROPINE LIBERATING HORMONE AND PROCEDURES RELATED TO THEM
CA2683431C (en) 2007-04-06 2015-06-09 Neurocrine Biosciences Inc. Gonadotropin-releasing hormone receptor antagonists and methods relating thereto

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5559207A (en) * 1989-03-06 1996-09-24 Board Of Regents, University Of Texas Texaphyrin metal complex mediated ester hydrolysis

Also Published As

Publication number Publication date
NO970885D0 (en) 1997-02-27
AU3519095A (en) 1996-03-27
NO970885L (en) 1997-04-25
JPH10505353A (en) 1998-05-26
HUT77034A (en) 1998-03-02
FI970696A0 (en) 1997-02-19
CA2197785A1 (en) 1996-03-14
WO1996007667A1 (en) 1996-03-14
EP0778845A1 (en) 1997-06-18
FI970696A7 (en) 1997-02-19

Similar Documents

Publication Publication Date Title
FI962799A7 (en) Preparation containing nucleic acids, its manufacture and use
FI973363A7 (en) Composition containing nucleic acids, its preparation and use
FI971176L (en) DNA photocleavage using texapyrins
AU2206800A (en) Targeted molecular bar codes and methods for using the same
AU2215995A (en) Freeze-dried compositions comprising rna
EE9500064A (en) Substituted 1H-imidazoles, methods for their preparation, and pharmaceutical compositions
NL300150I1 (en) 4 "-substituted 9-deoxo-9A-AZA-9A-homoerythromycin-A derivatives.
NO995925D0 (en) Pharmaceutical compositions comprising cyclodextrins
FI963183A0 (en) Aqueous dispersion composition, and a composition using it
NO20000231D0 (en) Dolastatin-15 derivatives
ATE268758T1 (en) HYPOLIPIDEMIC PROPANOLAMINE DERIVATIVES
IL137162A0 (en) 2,3,4,5-tetrahydro -1h- [1,4]-benzodiazepine -3- hydroxamic acids as matrix metalloproteinase inhibitors
FI972264L (en) Betaine product, method for its preparation, and use thereof
FI970740A7 (en) Functional terpyridine-metal complexes, methods for their preparation and oligonucleotide conjugates with terpyridine-metal complexes
FI953578L (en) Xylanase, microorganism producing it, DNA molecule, method for producing xylanase and its use
FI970696A7 (en) Oligonucleotide conjugates, compositions and methods for degrading ribonucleic acids
FI972988A0 (en) Methods and pharmaceutical compositions using desmethylselegiline
EE200000129A (en) Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-10-ol, process for their preparation and use as pharmaceuticals
FI972186L (en) Method for producing isomaltulose and other products
EP0799050A4 (en) ANNEXINE-GALACTOSE RADIOMARK GROUP CONJUGATES
EE03996B1 (en) Pharmaceutical compositions, process for their preparation and use
ZA967817B (en) Phenylacetic acids, their preparation, and compositions comprising them.
FI955399L (en) Polyol composition, method for its preparation and uses thereof
FI982412L (en) Feed and method for its preparation
FI933507A7 (en) Bicyclopolyazamacrocyclophosphonic acids, their complexes and conjugates for use as contrast agents and method for their preparation