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FI970114A7 - Adenovirus containing the gene encoding NO synthase - Google Patents

Adenovirus containing the gene encoding NO synthase Download PDF

Info

Publication number
FI970114A7
FI970114A7 FI970114A FI970114A FI970114A7 FI 970114 A7 FI970114 A7 FI 970114A7 FI 970114 A FI970114 A FI 970114A FI 970114 A FI970114 A FI 970114A FI 970114 A7 FI970114 A7 FI 970114A7
Authority
FI
Finland
Prior art keywords
synthase
gene encoding
adenovirus containing
adenovirus
gene
Prior art date
Application number
FI970114A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI970114A0 (en
FI970114L (en
Inventor
Didier Branellec
Patrice Denefle
Andrees Bohme
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI970114A0 publication Critical patent/FI970114A0/en
Publication of FI970114A7 publication Critical patent/FI970114A7/en
Publication of FI970114L publication Critical patent/FI970114L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0071Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0073Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen 1.14.13
    • C12N9/0075Nitric-oxide synthase (1.14.13.39)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y114/00Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/13Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with NADH or NADPH as one donor, and incorporation of one atom of oxygen (1.14.13)
    • C12Y114/13039Nitric-oxide synthase (NADPH dependent) (1.14.13.39)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
FI970114A 1994-07-12 1995-07-07 Adenovirus containing the gene encoding NO synthase FI970114L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9408657A FR2722507B1 (en) 1994-07-12 1994-07-12 ADENOVIRUS COMPRISING A GENE ENCODING NO SYNTHASE
PCT/FR1995/000913 WO1996001902A1 (en) 1994-07-12 1995-07-07 Adenovirus comprising a gene coding for an no synthase

Publications (3)

Publication Number Publication Date
FI970114A0 FI970114A0 (en) 1997-01-10
FI970114A7 true FI970114A7 (en) 1997-01-10
FI970114L FI970114L (en) 1997-01-10

Family

ID=9465319

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970114A FI970114L (en) 1994-07-12 1995-07-07 Adenovirus containing the gene encoding NO synthase

Country Status (11)

Country Link
EP (1) EP0770133A1 (en)
JP (1) JPH10502533A (en)
AU (1) AU691008B2 (en)
CA (1) CA2193263A1 (en)
FI (1) FI970114L (en)
FR (1) FR2722507B1 (en)
IL (1) IL114565A0 (en)
MX (1) MX9700298A (en)
NO (1) NO970048L (en)
WO (1) WO1996001902A1 (en)
ZA (1) ZA955797B (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5833651A (en) * 1996-11-08 1998-11-10 Medtronic, Inc. Therapeutic intraluminal stents
EP1054991A1 (en) 1998-02-11 2000-11-29 Genvec, Inc. Vectors, cells and methods for the production of deleterious viral eukaryotic gene transfer vectors
US6206914B1 (en) 1998-04-30 2001-03-27 Medtronic, Inc. Implantable system with drug-eluting cells for on-demand local drug delivery
EP1020520A1 (en) * 1999-01-15 2000-07-19 Introgene B.V. Prevention of immune related removal of cells from the mammalian body, mutant PML molecules useful therefor
HRP20010797A2 (en) 1999-04-16 2003-02-28 Univ Yale eNOS MUTATIONS USEFUL FOR GENE THERAPY AND THERAPEUTIC SCREENING
FR2793142A1 (en) * 1999-05-04 2000-11-10 Aventis Pharma Sa Antisense oligonucleotides of an inductible isoform of nitrogen monoxide synthase, used to treat cerebral ischemia
AU5081200A (en) * 1999-05-04 2000-11-17 Aventis Pharma S.A. Use of inducible no-synthase antisense oligonucleotides for preventing and treating cerebral ischemia
EP1067190A1 (en) * 1999-07-09 2001-01-10 Introgene B.V. Gene therapy for enhancing and/or inducing angiogenesis
EP1076091A1 (en) * 1999-08-09 2001-02-14 Universite Catholique De Louvain Medicament for the prevention and/or the treatment of ischemic heart and peripheral vascular diseases, tumour and wounds

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5281627A (en) * 1992-05-28 1994-01-25 Cornell Research Foundation, Inc. Substituted arginines and substituted homoarginines and use thereof
WO1994011506A1 (en) * 1992-11-18 1994-05-26 Arch Development Corporation Adenovirus-mediated gene transfer to cardiac and vascular smooth muscle
FR2704556B1 (en) * 1993-04-30 1995-07-13 Rhone Poulenc Rorer Sa Recombinant viruses and their use in gene therapy.
FR2705361B1 (en) * 1993-05-18 1995-08-04 Centre Nat Rech Scient Viral vectors and use in gene therapy.
DE69432413T2 (en) * 1993-06-11 2004-05-13 The Board Of Trustees Of The Leland Stanford Junior University, Stanford TREATMENT OF DEGENERATIVE VESSEL DISEASES BY MODULATING THE ENDOGENIC NITROGEN PRODUCTION OR ACTIVITY
FR2707494B1 (en) * 1993-07-02 1995-08-25 Roussel Uclaf New use of beta-naphthoquinone derivatives and their salts.
US6682728B1 (en) * 1993-10-13 2004-01-27 The United States Of America As Represented By The Department Of Health And Human Services Efficient and selective adenoviral-mediated gene transfer into vascular neointima

Also Published As

Publication number Publication date
MX9700298A (en) 1997-05-31
JPH10502533A (en) 1998-03-10
WO1996001902A1 (en) 1996-01-25
NO970048D0 (en) 1997-01-07
FI970114A0 (en) 1997-01-10
IL114565A0 (en) 1995-11-27
ZA955797B (en) 1996-02-26
AU691008B2 (en) 1998-05-07
EP0770133A1 (en) 1997-05-02
FR2722507B1 (en) 1996-08-14
FR2722507A1 (en) 1996-01-19
CA2193263A1 (en) 1996-01-25
NO970048L (en) 1997-01-07
AU2930695A (en) 1996-02-09
FI970114L (en) 1997-01-10

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