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FI974640L - 1,6-disubstituted isochromans for the treatment of migraine - Google Patents

1,6-disubstituted isochromans for the treatment of migraine Download PDF

Info

Publication number
FI974640L
FI974640L FI974640A FI974640A FI974640L FI 974640 L FI974640 L FI 974640L FI 974640 A FI974640 A FI 974640A FI 974640 A FI974640 A FI 974640A FI 974640 L FI974640 L FI 974640L
Authority
FI
Finland
Prior art keywords
isochromans
migraine
disubstituted
treatment
disubstituted isochromans
Prior art date
Application number
FI974640A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI974640A7 (en
FI974640A0 (en
Inventor
Michael D Ennis
Ruth E Tenbrink
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of FI974640A7 publication Critical patent/FI974640A7/en
Publication of FI974640A0 publication Critical patent/FI974640A0/en
Publication of FI974640L publication Critical patent/FI974640L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/06Antimigraine agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76Benzo[c]pyrans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI974640A 1995-06-30 1996-06-07 1,6-disubstituted isochromans for the treatment of migraine FI974640L (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US74195P 1995-06-30 1995-06-30
US1123496P 1996-02-06 1996-02-06
PCT/US1996/008681 WO1997002259A1 (en) 1995-06-30 1996-06-07 1,6-disubstituted isochromans for treatment of migraine headaches

Publications (3)

Publication Number Publication Date
FI974640A7 FI974640A7 (en) 1997-12-30
FI974640A0 FI974640A0 (en) 1997-12-30
FI974640L true FI974640L (en) 1997-12-30

Family

ID=26668092

Family Applications (1)

Application Number Title Priority Date Filing Date
FI974640A FI974640L (en) 1995-06-30 1996-06-07 1,6-disubstituted isochromans for the treatment of migraine

Country Status (12)

Country Link
EP (1) EP0836599A1 (en)
JP (1) JPH11509532A (en)
AU (1) AU6252296A (en)
BR (1) BR9609631A (en)
CA (1) CA2225282A1 (en)
CZ (1) CZ418597A3 (en)
FI (1) FI974640L (en)
MX (1) MX9710260A (en)
NO (1) NO976112L (en)
PL (1) PL324319A1 (en)
SK (1) SK164297A3 (en)
WO (1) WO1997002259A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2370270A (en) * 2000-12-20 2002-06-26 Lilly Co Eli Pharmaceutical compounds
US7335660B2 (en) 2001-12-19 2008-02-26 Eli Lilly And Company Isochroman compounds for treatment of CNS disorders
GB0130339D0 (en) * 2001-12-19 2002-02-06 Lilly Co Eli Isochroman compounds
US7110576B2 (en) 2002-12-30 2006-09-19 Pitney Bowes Inc. System and method for authenticating a mailpiece sender
BRPI0510642A (en) 2004-05-05 2007-11-20 Hoffmann La Roche arylsulfonyl benzodioxanes useful for modulating 5-ht6 receptor, 5ht2a receptor or both
JP4738418B2 (en) 2004-12-21 2011-08-03 エフ.ホフマン−ラ ロシュ アーゲー Chroman derivatives and their use in the treatment of CNS disorders
ATE455755T1 (en) 2004-12-21 2010-02-15 Hoffmann La Roche TETRALIN AND INDANDE DERIVATIVES AND THEIR APPLICATIONS
RU2396264C2 (en) 2004-12-21 2010-08-10 Ф. Хоффманн-Ля Рош Аг Chromane derivatives and use thereof as 5-ht receptor ligands
ES2314749T3 (en) 2004-12-21 2009-03-16 F. Hoffmann-La Roche Ag DERIVATIVES OF TETRALINA AND INDANO AND USES OF THE SAME AS 5-HT ANTAGONISTS.
MX2007007481A (en) 2004-12-21 2007-07-20 Hoffmann La Roche Tetralin and indane derivatives and uses thereof.
ES2359735T3 (en) 2005-11-03 2011-05-26 F. Hoffmann-La Roche Ag ARYLSULPHONYL CHROMANES AS 5-HT6 INHIBITORS.
WO2007147763A1 (en) 2006-06-20 2007-12-27 F. Hoffmann-La Roche Ag Arylsulfonyl naphthalene derivatives and uses thereof
KR101064001B1 (en) 2006-06-20 2011-09-08 에프. 호프만-라 로슈 아게 Arylsulfonamidyl tetralin derivatives and uses thereof
EP2035370A2 (en) 2006-06-20 2009-03-18 F. Hoffmann-Roche AG Tetralin and indane derivatives and uses thereof
WO2010101299A1 (en) * 2009-03-05 2010-09-10 住友化学株式会社 Method for producing halogen-substituted benzene dimethanol

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1552004A (en) * 1976-05-26 1979-09-05 Takeda Chemical Industries Ltd Isochroman derivatives
JP3773255B2 (en) * 1993-12-28 2006-05-10 ファルマシア・アンド・アップジョン・カンパニー Heterocyclic compounds for treating CNS and cardiovascular diseases

Also Published As

Publication number Publication date
FI974640A7 (en) 1997-12-30
EP0836599A1 (en) 1998-04-22
NO976112L (en) 1998-03-02
FI974640A0 (en) 1997-12-30
BR9609631A (en) 1999-03-02
PL324319A1 (en) 1998-05-25
NO976112D0 (en) 1997-12-29
CA2225282A1 (en) 1997-01-23
SK164297A3 (en) 1998-09-09
CZ418597A3 (en) 1998-06-17
MX9710260A (en) 1998-03-29
JPH11509532A (en) 1999-08-24
WO1997002259A1 (en) 1997-01-23
AU6252296A (en) 1997-02-05

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