FI963424L - Menetelmä terapeuttisesti aktiivisten tiofeenisulfonamidien valmistamiseksi - Google Patents

Menetelmä terapeuttisesti aktiivisten tiofeenisulfonamidien valmistamiseksi Download PDF

Info

Publication number: FI963424L
Authority: FI; Finland
Prior art keywords: therapeutically active; preparing therapeutically; active thiophene; thiophene sulfonamides; sulfonamides
Prior art date: 1990-04-09

Application number

FI963424A

Other languages

English (en)

Swedish (sv)

Other versions

FI963424A7 (fi

FI963424A0 (fi

Inventor

Thomas R Dean

Hwang-Hsing Chen

Jesse A May

Anura Pathmasiri Dantanarayana

Daniel Kuzmich

Paul W Zinke

Raymond Eugene Conrow

Michael E Deason

Mark Thomas Dupriest

Original Assignee

Alcon Lab Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-04-09

Filing date

1991-04-03

Publication date

1996-09-02

1991-04-03 Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc

1991-04-03 Priority to FI963424A priority Critical patent/FI963424A0/fi

1996-09-02 Publication of FI963424A7 publication Critical patent/FI963424A7/fi

1996-09-02 Publication of FI963424L publication Critical patent/FI963424L/fi

1996-09-02 Publication of FI963424A0 publication Critical patent/FI963424A0/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/30—Hetero atoms other than halogen
- C07D333/34—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Ophthalmology & Optometry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Lubricants (AREA)

FI963424A 1990-04-09 1991-04-03 Menetelmä terapeuttisesti aktiivisten tiofeenisulfonamidien valmistamiseksi FI963424A0 (fi)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
FI963424A FI963424A0 (fi)	1990-04-09	1991-04-03	Menetelmä terapeuttisesti aktiivisten tiofeenisulfonamidien valmistamiseksi

Applications Claiming Priority (5)

Application Number	Priority Date	Filing Date	Title
US50673090A	1990-04-09	1990-04-09
US07/618,765 US5153192A (en)	1990-04-09	1990-11-27	Thiophene sulfonamides useful as carbonic anhydrase inhibitors
FI924553A FI924553A7 (fi)	1990-04-09	1991-04-03	Tiofeenisulfoniamideja käyttökelpoisia hiilianhydraasi-inhibiittoreina
PCT/US1991/002262 WO1991015486A1 (en)	1990-04-09	1991-04-03	Thiophene sulfonamides useful as carbonic anydrase inhibitors
FI963424A FI963424A0 (fi)	1990-04-09	1991-04-03	Menetelmä terapeuttisesti aktiivisten tiofeenisulfonamidien valmistamiseksi

Publications (3)

Publication Number	Publication Date
FI963424A7 FI963424A7 (fi)	1996-09-02
FI963424L true FI963424L (fi)	1996-09-02
FI963424A0 FI963424A0 (fi)	1996-09-02

Family

ID=27055558

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
FI924553A FI924553A7 (fi)	1990-04-09	1991-04-03	Tiofeenisulfoniamideja käyttökelpoisia hiilianhydraasi-inhibiittoreina
FI963424A FI963424A0 (fi)	1990-04-09	1991-04-03	Menetelmä terapeuttisesti aktiivisten tiofeenisulfonamidien valmistamiseksi

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
FI924553A FI924553A7 (fi)	1990-04-09	1991-04-03	Tiofeenisulfoniamideja käyttökelpoisia hiilianhydraasi-inhibiittoreina

Country Status (19)

Country	Link
US (2)	US5153192A (fi)
EP (1)	EP0527801B1 (fi)
JP (1)	JP2562394B2 (fi)
KR (1)	KR100196414B1 (fi)
AT (1)	ATE221527T1 (fi)
AU (1)	AU655924B2 (fi)
BR (1)	BR9106330A (fi)
CA (1)	CA2080223C (fi)
DE (3)	DE10299054I1 (fi)
DK (1)	DK0527801T3 (fi)
ES (1)	ES2180530T3 (fi)
FI (2)	FI924553A7 (fi)
IL (1)	IL97800A (fi)
LU (2)	LU90935I2 (fi)
NL (2)	NL300098I2 (fi)
NO (1)	NO923948L (fi)
NZ (1)	NZ237754A (fi)
WO (1)	WO1991015486A1 (fi)
ZA (1)	ZA912580B (fi)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
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US5932572A (en) *	1992-02-21	1999-08-03	Alcon Laboratories, Inc.	Topical anti-glaucoma compositions
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US5276025A (en) *	1992-09-09	1994-01-04	Merck & Co., Inc.	Heterobicyclic sulfonamides
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US6242441B1 (en)	1997-12-23	2001-06-05	Alcon Laboratories, Inc.	Use of brinzolamide to prevent visual field loss
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EP1058546A4 (en) *	1998-03-06	2004-07-28	Univ Texas	COMPILATIONS AND METHODS FOR THE TREATMENT OF MACULA DISEASES
US5948801A (en) *	1998-03-09	1999-09-07	Alcon Laboratories, Inc.	Treatment of retinal edema with brinzolamide
US6960579B1 (en) *	1998-05-19	2005-11-01	Alcon Manufacturing, Ltd.	Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
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US9730638B2 (en)	2013-03-13	2017-08-15	Glaukos Corporation	Intraocular physiological sensor
UA116273C2 (uk)	2013-10-17	2018-02-26	Сентісс Фарма Прайвет Лімітед	Офтальмологічний фармацевтичний склад, що не містить консерванта
US10463674B2 (en)	2013-11-08	2019-11-05	Sentiss Pharma Private Limited	Process for manufacturing sterile ophthalmic pharmaceutical suspensions
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1990
- 1990-11-27 US US07/618,765 patent/US5153192A/en not_active Expired - Lifetime
1991
- 1991-04-03 JP JP3508001A patent/JP2562394B2/ja not_active Expired - Lifetime
- 1991-04-03 DK DK91908317T patent/DK0527801T3/da active
- 1991-04-03 CA CA002080223A patent/CA2080223C/en not_active Expired - Lifetime
- 1991-04-03 WO PCT/US1991/002262 patent/WO1991015486A1/en not_active Ceased
- 1991-04-03 DE DE1991633080 patent/DE10299054I1/de active Pending
- 1991-04-03 ES ES91908317T patent/ES2180530T3/es not_active Expired - Lifetime
- 1991-04-03 BR BR919106330A patent/BR9106330A/pt not_active Application Discontinuation
- 1991-04-03 AT AT91908317T patent/ATE221527T1/de active
- 1991-04-03 KR KR1019920702476A patent/KR100196414B1/ko not_active Expired - Lifetime
- 1991-04-03 EP EP91908317A patent/EP0527801B1/en not_active Expired - Lifetime
- 1991-04-03 FI FI924553A patent/FI924553A7/fi not_active Application Discontinuation
- 1991-04-03 FI FI963424A patent/FI963424A0/fi not_active Application Discontinuation
- 1991-04-03 AU AU77467/91A patent/AU655924B2/en not_active Expired
- 1991-04-03 DE DE69133080T patent/DE69133080T2/de not_active Expired - Lifetime
- 1991-04-03 DE DE122009000026C patent/DE122009000026I1/de active Pending
- 1991-04-08 ZA ZA912580A patent/ZA912580B/xx unknown
- 1991-04-09 NZ NZ237754A patent/NZ237754A/en unknown
- 1991-04-09 IL IL9780091A patent/IL97800A/xx not_active IP Right Cessation
- 1991-10-09 US US07/775,313 patent/US5240923A/en not_active Expired - Lifetime
1992
- 1992-10-09 NO NO92923948A patent/NO923948L/no unknown
2002
- 2002-07-05 LU LU90935C patent/LU90935I2/fr unknown
- 2002-09-04 NL NL300098C patent/NL300098I2/nl unknown
2009
- 2009-04-22 LU LU91555C patent/LU91555I2/fr unknown
- 2009-05-11 NL NL300389C patent/NL300389I1/nl unknown

Also Published As

Publication number	Publication date
NL300098I2 (nl)	2003-01-06
KR100196414B1 (ko)	1999-06-15
US5153192A (en)	1992-10-06
NL300389I1 (nl)	2009-07-01
FI924553L (fi)	1992-10-08
IL97800A (en)	1997-08-14
EP0527801A4 (en)	1993-03-10
US5240923A (en)	1993-08-31
AU655924B2 (en)	1995-01-19
FI963424A7 (fi)	1996-09-02
KR930700490A (ko)	1993-03-15
WO1991015486A1 (en)	1991-10-17
EP0527801B1 (en)	2002-07-31
NL300098I1 (nl)	2002-11-01
HK1014186A1 (en)	1999-09-24
EP0527801A1 (en)	1993-02-24
DK0527801T3 (da)	2002-11-25
CA2080223C (en)	2000-11-07
DE69133080D1 (de)	2002-09-05
ES2180530T3 (es)	2003-02-16
AU7746791A (en)	1991-10-30
JP2562394B2 (ja)	1996-12-11
LU90935I2 (en)	2002-09-05
BR9106330A (pt)	1993-04-20
FI924553A0 (fi)	1992-10-08
CA2080223A1 (en)	1991-10-10
JPH05508832A (ja)	1993-12-09
ATE221527T1 (de)	2002-08-15
FI963424A0 (fi)	1996-09-02
LU91555I2 (fr)	2009-06-22
NO923948L (no)	1992-12-08
DE69133080T2 (de)	2003-03-27
DE122009000026I1 (de)	2010-01-28
NO923948D0 (no)	1992-10-09
DE10299054I1 (de)	2006-06-08
NZ237754A (en)	1992-08-26
FI924553A7 (fi)	1992-10-08
ZA912580B (en)	1992-01-29
IL97800A0 (en)	1992-06-21

Publication	Publication Date	Title
FI963424L (fi)	1996-09-02	Menetelmä terapeuttisesti aktiivisten tiofeenisulfonamidien valmistamiseksi
FI906204L (fi)	1991-06-23	Menetelmä farmaseuttisesti vaikuttavien peptidiyhdisteiden valmistamiseksi
FI890652A7 (fi)	1989-08-11	Menetelmä terapeuttisesti aktiivisten substituoitujen indolyylipyrrolijohdannaisten valmistamiseksi
FI915656A7 (fi)	1991-11-29	Terapeuttiset hyödylliset 2-aminotetraliinijohdannaiset
FI870903L (fi)	1987-09-08	Menetelmä terapeuttisesti aktiivisten alfa-heterosykleillä substituoitujen tolunitriilien valmistamiseksi
FI895531A0 (fi)	1989-11-21	Menetelmä valmistaa farmakologisesti vaikuttavia kinuklidiineja
FI883050L (fi)	1988-12-25	Menetelmä terapeuttisesti aktiivisten pyranoindolitsinokinoliinijohdannaisten valmistamiseksi
NO176759C (no)	1995-05-24	Analogifremgangsmåte for fremstilling av terapeutisk aktive 3-substituerte-2-oksindol-derivater
FI955939A0 (fi)	1995-12-11	Farmaseuttisesti aktiivisia CNS-yhdisteitä
FI893448L (fi)	1990-01-19	Menetelmä valmistaa terapeuttisesti aktiivinen ranitidiinisuola
FI892497L (fi)	1989-11-25	Menetelmä terapeuttisesti aktiivisten bentsamidijohdannaisten valmistamiseksi
IS1667B (is)	1997-11-14	Hliðstæð aðferð við framleiðslu á meðferðarvirkumbis-aza-bísýklískum efnasamböndum
DK1199307T3 (da)	2004-06-14	Farmaceutisk aktive benzoquinazolinforbindelser
IT1217573B (it)	1990-03-30	Benzammidi sostituite farmacologicamente attive
FI883300L (fi)	1989-01-15	Menetelmä uusien terapeuttisesti aktiivisten bentsotiofeenien valmistamiseksi
FI890123L (fi)	1989-07-15	Menetelmä valmistaa terapeuttisesti vaikuttavia indolyylipiperidiiniyhdisteitä
FI924642L (fi)	1992-10-14	Menetelmä terapeuttisesti aktiivisten 3-indolyylitioasetaattijohdannaisten valmistamiseksi
NO173784C (no)	1994-02-02	Anaslogifremgangsmaate for fremstilling av terapeutisk aktive tieno-tri-azolo-diazepinderivater
FI916058A7 (fi)	1992-06-28	Menetelmä terapeuttisesti aktiivisten dihydrobentsofuraanikarboksamidien valmistamiseksi
FI884660L (fi)	1989-04-13	Menetelmä terapeuttisesti aktiivisten 2,2-dimetyylikromeenijohdannaisten valmistamiseksi
FI911747L (fi)	1991-10-13	Menetelmä terapeuttisesti aktiivisten substituoitujen aromaattisten sulfonamidijohdannaisten valmistamiseksi
FI930626L (fi)	1993-02-12	Proteinstruktur hos vaexttoxingelonin
FI874789L (fi)	1988-05-05	Menetelmä valmistaa farmakologisesti aktiivisia substituoituja 1H-imidatsoleja
FI880103L (fi)	1988-01-11	Menetelmä terapeuttisesti aktiivisen sialosyylikolesterolin valmistamiseksi
FI880190L (fi)	1988-07-28	Menetelmä valmistaa terapeuttisesti vaikuttavia tetrahydrofuraanijohdoksia

Legal Events

Date	Code	Title	Description
1998-07-17	FD	Application lapsed