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FI962948L - Menetelmä vaikealiukoisten farmaseuttisesti aktiivisten aineiden liuottamiseksi - Google Patents

Menetelmä vaikealiukoisten farmaseuttisesti aktiivisten aineiden liuottamiseksi Download PDF

Info

Publication number
FI962948L
FI962948L FI962948A FI962948A FI962948L FI 962948 L FI962948 L FI 962948L FI 962948 A FI962948 A FI 962948A FI 962948 A FI962948 A FI 962948A FI 962948 L FI962948 L FI 962948L
Authority
FI
Finland
Prior art keywords
active substances
pharmaceutically active
poorly soluble
soluble pharmaceutically
dissolving poorly
Prior art date
Application number
FI962948A
Other languages
English (en)
Swedish (sv)
Other versions
FI962948A7 (fi
FI962948A0 (fi
Inventor
Dadi Jamshed Dhabhar
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of FI962948A7 publication Critical patent/FI962948A7/fi
Publication of FI962948L publication Critical patent/FI962948L/fi
Publication of FI962948A0 publication Critical patent/FI962948A0/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI962948A 1994-01-24 1995-01-24 Menetelmä vaikealiukoisten farmaseuttisesti aktiivisten aineiden liuottamiseksi FI962948A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18557694A 1994-01-24 1994-01-24
PCT/US1995/001018 WO1995019759A1 (en) 1994-01-24 1995-01-24 Process for solubilizing difficultly soluble pharmaceutical actives

Publications (3)

Publication Number Publication Date
FI962948A7 FI962948A7 (fi) 1996-07-23
FI962948L true FI962948L (fi) 1996-07-23
FI962948A0 FI962948A0 (fi) 1996-07-23

Family

ID=22681571

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962948A FI962948A0 (fi) 1994-01-24 1995-01-24 Menetelmä vaikealiukoisten farmaseuttisesti aktiivisten aineiden liuottamiseksi

Country Status (14)

Country Link
EP (1) EP0741560A1 (fi)
JP (1) JPH09508128A (fi)
CN (1) CN1138827A (fi)
AU (1) AU706890B2 (fi)
BR (1) BR9506564A (fi)
CA (1) CA2181241C (fi)
CZ (1) CZ210496A3 (fi)
FI (1) FI962948A0 (fi)
MX (1) MX9602955A (fi)
NO (1) NO963052L (fi)
NZ (1) NZ279443A (fi)
PL (1) PL315635A1 (fi)
SK (1) SK96196A3 (fi)
WO (1) WO1995019759A1 (fi)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998058637A1 (en) * 1996-06-20 1998-12-30 Mcneil-Ppc Acetaminophen and diphenhydramine analgesics
ZA975444B (en) * 1996-06-20 1998-12-21 Mcneil Ppc Inc Acetaminophen and meclizine hydrochloride analgesics
FR2751875B1 (fr) * 1996-08-05 1998-12-24 Scr Newpharm Nouvelles formulations liquides stables a base de paracetamol et leur mode de preparation
US5763449A (en) * 1996-08-07 1998-06-09 Ascent Pediatrics, Inc. Pleasant-tasting aqueous liquid composition of a bitter-tasting drug
US6365180B1 (en) * 1998-01-20 2002-04-02 Glenn A. Meyer Oral liquid compositions
DE69940769D1 (de) 1998-01-20 2009-06-04 Applied Analytical Ind Inc Orale flüssige zusammensetzungen
US20020086878A1 (en) * 1999-01-11 2002-07-04 Douglas Joseph Dobrozsi Compositions having improved stability
US20020082307A1 (en) * 1999-01-11 2002-06-27 Dobrozsi Douglas Joseph Compositions having improved stability
US6846495B2 (en) 1999-01-11 2005-01-25 The Procter & Gamble Company Compositions having improved delivery of actives
US6211246B1 (en) * 1999-06-10 2001-04-03 Mcneil-Ppc, Inc. Rapidly absorbed liquid compositions
FR2796843B1 (fr) * 1999-07-29 2003-05-09 So Ge Val Sa Composition antipyretique concentree et stabilisee a usage veterinaire destine a etre incorporee a l'alimentation des animaux ainsi que procede d'incorporation de cette composition a l'eau de boisson d'animaux
US6251426B1 (en) * 1999-09-02 2001-06-26 Banner Pharmacaps, Inc. Ibuprofen-containing softgels
DE10011032A1 (de) * 2000-03-07 2001-09-13 Bayer Ag Acetylsalicylsäure-Lösungen
KR20020069387A (ko) * 2001-02-26 2002-09-04 진양제약주식회사 호박산독실아민 조성물 및 이 조성물을 함유한 연질캅셀제제
BR0211794A (pt) * 2001-07-31 2004-11-03 Wyeth Corp Composição farmacêutica e método para mascarar o sabor de pelo menos um composto farmaceuticamente ativo de sabor desagradável
US7101572B2 (en) * 2001-12-07 2006-09-05 Unilab Pharmatech, Ltd. Taste masked aqueous liquid pharmaceutical composition
CN100379406C (zh) * 2003-09-22 2008-04-09 北京德众万全药物技术开发有限公司 一种难溶性药物微丸的制备方法及包含该微丸的制剂
EP1959935A2 (en) * 2005-10-26 2008-08-27 Banner Pharmacaps Inc. Hydrophilic vehicle-based dual controlled release matrix system as capsule fill
DE102005053066A1 (de) 2005-11-04 2007-05-10 Basf Ag Verwendung von Copolymeren als Solubilisatoren für in Wasser schwerlöslichen Verbindungen
US20080300320A1 (en) * 2005-12-09 2008-12-04 Basf Se Use of Polyvinyl Lactam-Polyalkylene Block Copolymers as Solubilisers for Poorly Water-Soluble Compounds
US8637076B2 (en) 2006-06-01 2014-01-28 Cima Labs Inc. Prednisolone salt formulations
JP2008184430A (ja) * 2007-01-30 2008-08-14 Ss Pharmaceut Co Ltd ソフトカプセル
CA2690490C (en) * 2010-01-19 2012-06-26 Accucaps Industries Limited Pharmaceutical formulations of loratadine for encapsulation and combinations thereof
CA2690488C (en) * 2010-01-19 2013-06-11 Accucaps Industries Limited Pharmaceutical formulations of naproxen for soft gel encapsulation and combinations thereof
PT2528602T (pt) 2010-01-28 2017-01-12 Eagle Pharmaceuticals Inc Formulações de bendamustina
ES2943668T3 (es) 2012-03-20 2023-06-15 Eagle Pharmaceuticals Inc Composiciones líquidas de bendamustina para su uso en un método para tratar afecciones que responden a la bendamustina en pacientes que requieren volúmenes reducidos para administración
EP4360621A3 (en) 2012-03-20 2024-05-22 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
CN105007891B (zh) 2013-02-28 2018-01-16 辉瑞公司 新液体组合物的增强的稳定性
GB201506755D0 (en) * 2015-04-21 2015-06-03 Reckitt Benckiser Llc Novel pharmaceutical formulation
TWI586379B (zh) 2015-06-29 2017-06-11 永信藥品工業股份有限公司 一種製作難溶藥物固體劑型的方法
WO2017062997A1 (en) 2015-10-09 2017-04-13 Reckitt Benckiser Llc Pharmaceutical formulation
CN115957194B (zh) * 2021-10-08 2025-05-16 人福普克药业（武汉）有限公司 一种用于感冒软胶囊中内容物的溶剂体系及感冒软胶囊

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5141961A (en) * 1991-06-27 1992-08-25 Richrdson-Vicks Inc. Process for solubilizing difficulty soluble pharmaceutical actives

Also Published As

Publication number Publication date
FI962948A7 (fi) 1996-07-23
CA2181241A1 (en) 1995-07-27
NO963052L (no) 1996-09-24
WO1995019759A1 (en) 1995-07-27
BR9506564A (pt) 1997-09-02
NO963052D0 (no) 1996-07-22
NZ279443A (en) 1998-04-27
AU1607595A (en) 1995-08-08
PL315635A1 (en) 1996-11-25
FI962948A0 (fi) 1996-07-23
SK96196A3 (en) 1997-03-05
CN1138827A (zh) 1996-12-25
CA2181241C (en) 2000-04-25
AU706890B2 (en) 1999-07-01
MX9602955A (es) 1997-06-28
CZ210496A3 (en) 1996-12-11
JPH09508128A (ja) 1997-08-19
EP0741560A1 (en) 1996-11-13

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