FI961996L - Pitkitetysti vapauttavat valmisteet metoprololin 24 tunnin pituiseksi vapauttamiseksi - Google Patents
Pitkitetysti vapauttavat valmisteet metoprololin 24 tunnin pituiseksi vapauttamiseksi Download PDFInfo
- Publication number
- FI961996L FI961996L FI961996A FI961996A FI961996L FI 961996 L FI961996 L FI 961996L FI 961996 A FI961996 A FI 961996A FI 961996 A FI961996 A FI 961996A FI 961996 L FI961996 L FI 961996L
- Authority
- FI
- Finland
- Prior art keywords
- release
- metoprolol
- sustained
- hour
- preparations
- Prior art date
Links
- 239000003405 delayed action preparation Substances 0.000 title 1
- IUBSYMUCCVWXPE-UHFFFAOYSA-N metoprolol Chemical compound COCCC1=CC=C(OCC(O)CNC(C)C)C=C1 IUBSYMUCCVWXPE-UHFFFAOYSA-N 0.000 title 1
- 229960002237 metoprolol Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/151,272 US5399358A (en) | 1993-11-12 | 1993-11-12 | Sustained release formulations for 24 hour release of metroprolol |
| US15127293 | 1993-11-12 | ||
| PCT/US1994/012139 WO1995013055A1 (en) | 1993-11-12 | 1994-10-19 | Sustained release formulations for 24 hour release of metoprolol |
| US9412139 | 1994-10-19 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI961996A0 FI961996A0 (fi) | 1996-05-10 |
| FI961996L true FI961996L (fi) | 1996-05-29 |
| FI116450B FI116450B (fi) | 2005-11-30 |
Family
ID=22538025
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI961996A FI116450B (fi) | 1993-11-12 | 1996-05-10 | Menetelmä valmistaa metoprololin 24 tunnin valmistetta |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5399358A (fi) |
| EP (1) | EP0730444B1 (fi) |
| JP (1) | JP2832248B2 (fi) |
| KR (1) | KR100197841B1 (fi) |
| CN (1) | CN1198596C (fi) |
| AT (1) | ATE230980T1 (fi) |
| AU (1) | AU675370B2 (fi) |
| CA (1) | CA2171844C (fi) |
| DE (1) | DE69432025T2 (fi) |
| DK (1) | DK0730444T3 (fi) |
| ES (1) | ES2191034T3 (fi) |
| FI (1) | FI116450B (fi) |
| HU (1) | HU223612B1 (fi) |
| IL (1) | IL111400A (fi) |
| TW (1) | TW314469B (fi) |
| WO (1) | WO1995013055A1 (fi) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5773025A (en) * | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
| IS1736B (is) * | 1993-10-01 | 1999-12-30 | Astra Ab | Aðferð og tæki sem stuðla að aukinni samloðun agna |
| US5399362A (en) * | 1994-04-25 | 1995-03-21 | Edward Mendell Co., Inc. | Once-a-day metoprolol oral dosage form |
| ES2246961T3 (es) * | 1994-04-25 | 2006-03-01 | Penwest Pharmaceuticals Co. | Excipiente de liberacion sostenida. |
| WO1997026865A1 (en) * | 1996-01-29 | 1997-07-31 | Edward Mendell Co., Inc. | Sustained release excipient |
| TW486370B (en) * | 1996-12-25 | 2002-05-11 | Yamanouchi Pharma Co Ltd | Rapidly disintegrable pharmaceutical composition |
| IN186245B (fi) | 1997-09-19 | 2001-07-14 | Ranbaxy Lab Ltd | |
| JP4234803B2 (ja) | 1997-10-27 | 2009-03-04 | 久光製薬株式会社 | 薬物放出速度が制御された医薬組成物 |
| ATE391495T1 (de) * | 1999-09-30 | 2008-04-15 | Penwest Pharmaceuticals Co | Matrixsystem mit verzögerter freisetzung für hochlösliche wirkstoffe |
| IL157634A0 (en) * | 2001-03-13 | 2004-03-28 | Penwest Pharmaceuticals Co | Chronotherapeutic dosage forms containing glucocorticosteroid |
| US20030129234A1 (en) * | 2001-07-06 | 2003-07-10 | Penwest Pharmaceuticals Company | Methods of making sustained release formulations of oxymorphone |
| DE60219478T2 (de) * | 2001-07-06 | 2008-01-03 | Endo Pharmaceuticals Inc. | Orale gabe von 6-hydroxy-oxymorphon als analgetikum |
| EP1429730A4 (en) * | 2001-09-26 | 2010-06-16 | Penwest Pharmaceuticals Compan | OPIOID FORMULATIONS WITH REDUCED ABUSE POTENTIAL |
| US6635675B2 (en) | 2001-11-05 | 2003-10-21 | Cypress Bioscience, Inc. | Method of treating chronic fatigue syndrome |
| US20060018962A1 (en) * | 2002-03-22 | 2006-01-26 | Reza Eivaskhani | Sustained release formulation of tramadol |
| AU2003230805A1 (en) * | 2002-04-05 | 2003-10-27 | Penwest Pharmaceuticals Co. | Sustained release metoprolol formulations |
| US7214387B2 (en) * | 2002-08-02 | 2007-05-08 | Penwest Pharmaceuticals Company | Sustained release formulations of metformin |
| US6936574B2 (en) * | 2002-08-30 | 2005-08-30 | Halliburton Energy Services, Inc. | Process for controlling gas migration during well cementing |
| US7314640B2 (en) * | 2003-07-11 | 2008-01-01 | Mongkol Sriwongjanya | Formulation and process for drug loaded cores |
| US20050032879A1 (en) * | 2003-08-07 | 2005-02-10 | Temple Okarter | Formulations and use of a beta-blocker and an ACE-inhibitor for the treatment of cardiovascular diseases |
| WO2005027878A1 (en) * | 2003-09-19 | 2005-03-31 | Penwest Pharmaceuticals Co. | Delayed released dosage forms |
| AU2004273958A1 (en) * | 2003-09-19 | 2005-03-31 | Penwest Pharmaceuticals Co. | Chronotherapeutic dosage forms |
| US20060003001A1 (en) * | 2004-02-11 | 2006-01-05 | John Devane | Chronotherapeutic compositions and methods of their use |
| US20060105044A1 (en) * | 2004-05-20 | 2006-05-18 | Singh Bramah N | Sustained release formulations of sotalol |
| US8394812B2 (en) | 2005-08-24 | 2013-03-12 | Penwest Pharmaceuticals Co. | Sustained release formulations of nalbuphine |
| CA2881739C (en) * | 2005-08-24 | 2018-01-02 | Endo Pharmaceuticals Inc. | Sustained release formulations of nalbuphine |
| US20070053983A1 (en) * | 2005-09-06 | 2007-03-08 | Girish Jain | Extended release compositions of metoprolol succinate |
| US20070092573A1 (en) * | 2005-10-24 | 2007-04-26 | Laxminarayan Joshi | Stabilized extended release pharmaceutical compositions comprising a beta-adrenoreceptor antagonist |
| WO2007059372A2 (en) * | 2005-11-09 | 2007-05-24 | St. Jude Children's Research Hospital | Use of chloroquine to treat metabolic syndrome |
| US8691272B2 (en) * | 2005-12-30 | 2014-04-08 | Intelgenx Corp. | Multilayer tablet |
| US20070212414A1 (en) * | 2006-03-08 | 2007-09-13 | Penwest Pharmaceuticals Co. | Ethanol-resistant sustained release formulations |
| US8124598B2 (en) * | 2006-09-14 | 2012-02-28 | Sharon Sageman | 7-keto DHEA for psychiatric use |
| US20080181947A1 (en) * | 2006-09-26 | 2008-07-31 | Astellas Pharma Inc. | Controlled release dosage form of tacrolimus |
| US20080085303A1 (en) * | 2006-10-10 | 2008-04-10 | Penwest Pharmaceuticals Co. | Robust sustained release formulations of oxymorphone and methods of use thereof |
| US20080085304A1 (en) * | 2006-10-10 | 2008-04-10 | Penwest Pharmaceuticals Co. | Robust sustained release formulations |
| US20080085305A1 (en) * | 2006-10-10 | 2008-04-10 | Penwest Pharmaceuticals Co. | Robust sustained release formulations of oxymorphone |
| CA2674039A1 (en) * | 2006-12-28 | 2008-07-17 | Astellas Pharma Inc. | Sustained release formulation for tacrolimus |
| US20100160274A1 (en) * | 2007-09-07 | 2010-06-24 | Sharon Sageman | 7-KETO DHEA for Psychiatric Use |
| WO2010015029A1 (en) | 2008-08-06 | 2010-02-11 | Gosforth Centre (Holdings) Pty Ltd | Compositions and methods for treating psychiatric disorders |
| DK3045043T3 (da) | 2009-02-26 | 2020-08-03 | Relmada Therapeutics Inc | Orale farmaceutiske sammensætninger af 3-hydroxy-n-methylmorphinan med forlænget frigivelse og fremgangsmåde til anvendelse |
| PL2255791T3 (pl) * | 2009-04-03 | 2012-05-31 | Zakl Farmaceutyczne Polpharma Sa | Kompozycja farmaceutyczna o przedłużonym uwalnianiu zawierająca bursztynian metoprololu |
| US20110136815A1 (en) * | 2009-12-08 | 2011-06-09 | Horst Zerbe | Solid oral film dosage forms and methods for making same |
| US10610528B2 (en) | 2009-12-08 | 2020-04-07 | Intelgenx Corp. | Solid oral film dosage forms and methods for making same |
| JP5849947B2 (ja) | 2010-03-29 | 2016-02-03 | アステラス製薬株式会社 | 放出制御医薬組成物 |
| GB201111712D0 (en) | 2011-07-08 | 2011-08-24 | Gosforth Ct Holdings Pty Ltd | Pharmaceutical compositions |
| US20150133516A1 (en) | 2013-11-13 | 2015-05-14 | Brian K. Adams | Methods and Compositions for Treating ADHD |
| AU2016288643A1 (en) | 2015-07-02 | 2018-02-22 | University Of Louisville Research Foundation, Inc. | Edible plant-derived microvesicle compositions for delivery of miRNA and methods for treatment of cancer |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4303691A (en) * | 1977-11-09 | 1981-12-01 | Anderson, Clayton & Co. | Proteinaceous food product |
| US4309405A (en) | 1979-08-09 | 1982-01-05 | American Home Products Corporation | Sustained release pharmaceutical compositions |
| US4764380A (en) * | 1982-03-22 | 1988-08-16 | Alza Corporation | Drug delivery system comprising a volume increasing matrix containing a plurality of tiny pills |
| US5081154A (en) * | 1984-01-10 | 1992-01-14 | Aktiebolaget Hassle | Metoprolol succinate |
| GB8518301D0 (en) * | 1985-07-19 | 1985-08-29 | Fujisawa Pharmaceutical Co | Hydrodynamically explosive systems |
| SE455836B (sv) * | 1985-10-11 | 1988-08-15 | Haessle Ab | Beredning med kontrollerad frisettning innehallande ett salt av metoprolol samt metod for framstellning av denna beredning |
| US4795642A (en) * | 1986-05-01 | 1989-01-03 | Pharmacaps, Inc. | Gelatin-encapsulated controlled-release composition |
| IT1198449B (it) * | 1986-10-13 | 1988-12-21 | F I D I Farmaceutici Italiani | Esteri di alcoli polivalenti di acido ialuronico |
| GB8628359D0 (en) * | 1986-11-27 | 1986-12-31 | Zyma Sa | Galenical formulation |
| US4968508A (en) * | 1987-02-27 | 1990-11-06 | Eli Lilly And Company | Sustained release matrix |
| US4792452A (en) * | 1987-07-28 | 1988-12-20 | E. R. Squibb & Sons, Inc. | Controlled release formulation |
| US4994276A (en) * | 1988-09-19 | 1991-02-19 | Edward Mendell Co., Inc. | Directly compressible sustained release excipient |
| SE8703881D0 (sv) * | 1987-10-08 | 1987-10-08 | Haessle Ab | New pharmaceutical preparation |
| US4857331A (en) * | 1988-03-31 | 1989-08-15 | Warner-Lambert Company | Sugarless pectin delivery system |
| US5047244A (en) * | 1988-06-03 | 1991-09-10 | Watson Laboratories, Inc. | Mucoadhesive carrier for delivery of therapeutical agent |
| US5169639A (en) * | 1988-09-19 | 1992-12-08 | Edward Mendell Co., Inc. | Controlled release verapamil tablets |
| US5128143A (en) * | 1988-09-19 | 1992-07-07 | Edward Mendell Co., Inc. | Sustained release excipient and tablet formulation |
| US5135757A (en) * | 1988-09-19 | 1992-08-04 | Edward Mendell Co., Inc. | Compressible sustained release solid dosage forms |
| US5032406A (en) * | 1989-02-21 | 1991-07-16 | Norwich Eaton Pharmaceuticals, Inc. | Dual-action tablet |
| US5271943A (en) * | 1989-10-27 | 1993-12-21 | Scott Health Care | Wound gel compositions containing sodium chloride and method of using them |
| US5215756A (en) * | 1989-12-22 | 1993-06-01 | Gole Dilip J | Preparation of pharmaceutical and other matrix systems by solid-state dissolution |
| US5169638A (en) * | 1991-10-23 | 1992-12-08 | E. R. Squibb & Sons, Inc. | Buoyant controlled release powder formulation |
| HU209251B (en) * | 1992-03-13 | 1994-04-28 | Synepos Ag | Process for producing stable, peroral solution drug forms with controlled release of active ingredient and comprising beta-blocking pharmacons |
| US5330761A (en) * | 1993-01-29 | 1994-07-19 | Edward Mendell Co. Inc. | Bioadhesive tablet for non-systemic use products |
| US5455046A (en) * | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
-
1993
- 1993-11-12 US US08/151,272 patent/US5399358A/en not_active Expired - Lifetime
-
1994
- 1994-10-19 DK DK94931991T patent/DK0730444T3/da active
- 1994-10-19 WO PCT/US1994/012139 patent/WO1995013055A1/en not_active Ceased
- 1994-10-19 JP JP7513847A patent/JP2832248B2/ja not_active Expired - Fee Related
- 1994-10-19 DE DE69432025T patent/DE69432025T2/de not_active Expired - Lifetime
- 1994-10-19 EP EP94931991A patent/EP0730444B1/en not_active Expired - Lifetime
- 1994-10-19 ES ES94931991T patent/ES2191034T3/es not_active Expired - Lifetime
- 1994-10-19 AT AT94931991T patent/ATE230980T1/de not_active IP Right Cessation
- 1994-10-19 HU HU9601008A patent/HU223612B1/hu not_active IP Right Cessation
- 1994-10-19 KR KR1019960702479A patent/KR100197841B1/ko not_active Expired - Fee Related
- 1994-10-19 CA CA002171844A patent/CA2171844C/en not_active Expired - Fee Related
- 1994-10-19 AU AU80875/94A patent/AU675370B2/en not_active Ceased
- 1994-10-25 IL IL11140094A patent/IL111400A/en not_active IP Right Cessation
- 1994-11-12 CN CNB941200892A patent/CN1198596C/zh not_active Expired - Fee Related
- 1994-11-15 TW TW083110556A patent/TW314469B/zh active
-
1996
- 1996-05-10 FI FI961996A patent/FI116450B/fi active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| ES2191034T3 (es) | 2003-09-01 |
| HU9601008D0 (en) | 1996-06-28 |
| JP2832248B2 (ja) | 1998-12-09 |
| TW314469B (fi) | 1997-09-01 |
| WO1995013055A1 (en) | 1995-05-18 |
| CA2171844A1 (en) | 1995-05-18 |
| EP0730444A1 (en) | 1996-09-11 |
| IL111400A (en) | 1999-03-12 |
| JPH08511807A (ja) | 1996-12-10 |
| FI116450B (fi) | 2005-11-30 |
| EP0730444A4 (en) | 1996-11-06 |
| FI961996A0 (fi) | 1996-05-10 |
| KR100197841B1 (ko) | 1999-06-15 |
| HU223612B1 (hu) | 2004-10-28 |
| HUT75881A (en) | 1997-05-28 |
| AU8087594A (en) | 1995-05-29 |
| AU675370B2 (en) | 1997-01-30 |
| CN1198596C (zh) | 2005-04-27 |
| DE69432025T2 (de) | 2003-10-16 |
| DK0730444T3 (da) | 2003-04-14 |
| CA2171844C (en) | 2000-05-30 |
| ATE230980T1 (de) | 2003-02-15 |
| DE69432025D1 (de) | 2003-02-20 |
| EP0730444B1 (en) | 2003-01-15 |
| CN1109328A (zh) | 1995-10-04 |
| IL111400A0 (en) | 1994-12-29 |
| US5399358A (en) | 1995-03-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Patent granted |
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