FI960850L - Use of quinoxalines in combination with protease inhibitors as a drug for the treatment of AIDS and/or HIV infections - Google Patents

Use of quinoxalines in combination with protease inhibitors as a drug for the treatment of AIDS and/or HIV infections Download PDF

Info

Publication number: FI960850L
Authority: FI; Finland
Prior art keywords: quinoxalines; aids; drug; treatment; combination
Prior art date: 1995-02-27

Application number

FI960850A

Other languages

Finnish (fi)

Swedish (sv)

Other versions

FI960850A7 (en

FI960850A0 (en

Inventor

Arnold Paessens

Martin Blunck

Guenther Riess

Joerg-Peter Kleim

Manfred Roesner

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-02-27

Filing date

1996-02-23

Publication date

1996-08-28

1996-02-23 Application filed by Bayer Ag filed Critical Bayer Ag

1996-02-23 Publication of FI960850A0 publication Critical patent/FI960850A0/en

1996-08-28 Publication of FI960850A7 publication Critical patent/FI960850A7/en

1996-08-28 Publication of FI960850L publication Critical patent/FI960850L/en

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Plural Heterocyclic Compounds (AREA)

FI960850A 1995-02-27 1996-02-23 Use of quinoxalines in combination with protease inhibitors as a drug for the treatment of AIDS and/or HIV infections FI960850L (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19506742A DE19506742A1 (en)	1995-02-27	1995-02-27	Use of quinoxalines in combination with protease inhibitors as medicaments for the treatment of AIDS and / or HIV infections

Publications (3)

Publication Number	Publication Date
FI960850A0 FI960850A0 (en)	1996-02-23
FI960850A7 FI960850A7 (en)	1996-08-28
FI960850L true FI960850L (en)	1996-08-28

Family

ID=7755115

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI960850A FI960850L (en)	1995-02-27	1996-02-23	Use of quinoxalines in combination with protease inhibitors as a drug for the treatment of AIDS and/or HIV infections

Country Status (19)

Country	Link
EP (1)	EP0728481A3 (en)
JP (1)	JPH08245392A (en)
KR (1)	KR960030951A (en)
CN (1)	CN1141196A (en)
AR (1)	AR003923A1 (en)
AU (1)	AU710158B2 (en)
BR (1)	BR9600809A (en)
CA (1)	CA2170222A1 (en)
CZ (1)	CZ57896A3 (en)
DE (1)	DE19506742A1 (en)
FI (1)	FI960850L (en)
HR (1)	HRP960070A2 (en)
HU (1)	HUP9600455A3 (en)
IL (1)	IL117247A (en)
NO (1)	NO960775L (en)
NZ (1)	NZ286058A (en)
PL (1)	PL312908A1 (en)
SK (1)	SK25196A3 (en)
ZA (1)	ZA961516B (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2270546A1 (en) *	1996-11-08	1998-05-22	Japan Energy Corporation	Aids remedy
DE19703131A1 (en) *	1997-01-29	1998-07-30	Bayer Ag	Use of quinoxaline in a combination of three with protease inhibitors and reverse transcriptase inhibitors as medicaments for the treatment of AIDS and / or HIV infections
US6635626B1 (en)	1997-08-25	2003-10-21	Bristol-Myers Squibb Co.	Imidazoquinoxaline protein tyrosine kinase inhibitors
US6235740B1 (en)	1997-08-25	2001-05-22	Bristol-Myers Squibb Co.	Imidazoquinoxaline protein tyrosine kinase inhibitors
US6436989B1 (en)	1997-12-24	2002-08-20	Vertex Pharmaceuticals, Incorporated	Prodrugs of aspartyl protease inhibitors
AU756838B2 (en) *	1998-03-04	2003-01-23	Bristol-Myers Squibb Company	Heterocyclo-substituted imidazopyrazine protein tyrosine kinase inhibitors
AU6329599A (en) *	1998-09-28	2000-04-17	Glaxo Group Limited	Antiviral combinations comprising (s)-2-ethyl -7-fluoro -3-oxo-3, 4-dihydro -2h-quinoxaline -1-carboxylic acid isopropyl ester
GB9911887D0 (en) *	1999-05-21	1999-07-21	Glaxo Group Ltd	Methods and medicaments for post exposure prophylaxis of an hiv infection
DE10013318A1 (en) *	2000-03-17	2001-09-20	Merck Patent Gmbh	Quinoxaline derivatives are used as photo-stable UV filters in cosmetic or pharmaceutical sunscreens for the hair or skin
EA200500846A1 (en)	2002-11-19	2005-12-29	Ачиллион Фармасьютикалз, Инк.	SUBSTITUTED ARYLTIOMOCHAMINES AND RELATED COMPOUNDS; VIRAL REPLICATION INHIBITORS
TW200600492A (en)	2004-05-18	2006-01-01	Achillion Pharmaceuticals Inc	Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
US7351709B2 (en)	2004-06-09	2008-04-01	Wyeth	Estrogen receptor ligands
CA2895404A1 (en) *	2012-12-20	2014-06-26	Bayer Pharma Aktiengesellschaft	Bet-protein-inhibiting dihydropyridopyrazinones
DE102017005091A1 (en)	2016-05-30	2017-11-30	Bayer Pharma Aktiengesellschaft	Substituted 3,4-dihydropyrido [2,3-b] pyrazine-2 (1H) -one
DE102017005089A1 (en)	2016-05-30	2017-11-30	Bayer Pharma Aktiengesellschaft	Substituted 3,4-dihydroquinoxaline-2 (1H) -one

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0509398B1 (en) *	1991-04-15	2001-09-19	Aventis Pharma Deutschland GmbH	Quinoxalines, process for their preparation and their use

1995
- 1995-02-27 DE DE19506742A patent/DE19506742A1/en not_active Withdrawn
1996
- 1996-02-13 HR HR19506742.8A patent/HRP960070A2/en not_active Application Discontinuation
- 1996-02-14 EP EP96102129A patent/EP0728481A3/en not_active Withdrawn
- 1996-02-14 AR ARP960101379A patent/AR003923A1/en unknown
- 1996-02-20 AU AU45615/96A patent/AU710158B2/en not_active Ceased
- 1996-02-23 PL PL96312908A patent/PL312908A1/en unknown
- 1996-02-23 CA CA002170222A patent/CA2170222A1/en not_active Abandoned
- 1996-02-23 JP JP8060286A patent/JPH08245392A/en active Pending
- 1996-02-23 FI FI960850A patent/FI960850L/en unknown
- 1996-02-23 NZ NZ286058A patent/NZ286058A/en unknown
- 1996-02-23 IL IL11724796A patent/IL117247A/en active IP Right Grant
- 1996-02-26 CZ CZ96578A patent/CZ57896A3/en unknown
- 1996-02-26 NO NO960775A patent/NO960775L/en not_active Application Discontinuation
- 1996-02-26 KR KR1019960004623A patent/KR960030951A/en not_active Withdrawn
- 1996-02-26 ZA ZA961516A patent/ZA961516B/en unknown
- 1996-02-26 BR BR9600809A patent/BR9600809A/en active Search and Examination
- 1996-02-26 HU HU9600455A patent/HUP9600455A3/en unknown
- 1996-02-26 SK SK251-96A patent/SK25196A3/en unknown
- 1996-02-27 CN CN96102709A patent/CN1141196A/en active Pending

Also Published As

Publication number	Publication date
AU4561596A (en)	1996-09-05
AR003923A1 (en)	1998-09-30
NO960775L (en)	1996-08-28
HU9600455D0 (en)	1996-04-29
NO960775D0 (en)	1996-02-26
BR9600809A (en)	1997-12-23
HUP9600455A3 (en)	1998-04-28
FI960850A7 (en)	1996-08-28
KR960030951A (en)	1996-09-17
CA2170222A1 (en)	1996-08-28
FI960850A0 (en)	1996-02-23
ZA961516B (en)	1996-09-03
CN1141196A (en)	1997-01-29
CZ57896A3 (en)	1996-09-11
EP0728481A2 (en)	1996-08-28
IL117247A (en)	2000-10-31
IL117247A0 (en)	1996-06-18
PL312908A1 (en)	1996-09-02
NZ286058A (en)	1998-09-24
HUP9600455A2 (en)	1996-12-30
DE19506742A1 (en)	1996-08-29
AU710158B2 (en)	1999-09-16
HRP960070A2 (en)	1997-10-31
SK25196A3 (en)	1997-05-07
EP0728481A3 (en)	1998-07-08
JPH08245392A (en)	1996-09-24

Publication	Publication Date	Title
FI954580A7 (en)	1995-09-27	HIV protease inhibitors in pharmaceutical combinations for use in the treatment of AIDS
FI955315L (en)	1995-11-06	HIV protease inhibitors useful in the treatment of AIDS
FI981591A7 (en)	1998-07-10	HIV protease inhibitors useful in the treatment of AIDS
FI960850L (en)	1996-08-28	Use of quinoxalines in combination with protease inhibitors as a drug for the treatment of AIDS and/or HIV infections
FI906212A7 (en)	1991-06-19	HIV protease inhibitors, which are useful in the treatment of AIDS
FI893962A7 (en)	1990-02-25	HIV protease inhibitors, which are useful in the treatment of AIDS
CY2006007I2 (en)	2009-11-04	USE OF CGMP-PHOSPHODIESTERASE INHIBITORS IN THE TREATMENT OF IMPOTENCE
FI891716A7 (en)	1989-10-13	HIV protease inhibitors, which are useful in the treatment of AIDS
BR9406209A (en)	1996-02-06	Heterocyclic derivatives in the treatment of ischemia and related diseases
NO954635L (en)	1996-01-09	Ribozyme therapy for HIV infections and AIDS
FI923158A7 (en)	1993-01-11	HIV protease inhibitors, which are useful in the treatment of AIDS
FI935777L (en)	1994-06-23	HIV protease inhibitors useful in the treatment of AIDS
ZA98679B (en)	1998-08-05	Use of quinoxalines in a triple combination with protease inhibitors and reverse transcriptase inhibitors as medicaments for the treatment of aids and/or hiv infections
AU2002346594A1 (en)	2003-06-30	Use of hiv-1 protease inhibitors and their derivatives in the treatment of inflammation
EE03514B1 (en)	2001-10-15	A combination of compounds for the treatment of HIV infection or AIDS, its use and a pharmaceutical composition
GB9515802D0 (en)	1995-10-04	Hiv protease inhibitors useful for the treatment of aids
BR9914722A (en)	2001-07-10	Anticonvulsant derivatives useful in the treatment of alcohol dependence, addiction and abuse
PT1052991E (en)	2003-08-29	USING LOPERAMID FOR THE TREATMENT OF MICROBIAL INFECTIONS
IL143795A0 (en)	2002-04-21	Use of 3-isoxazolidinones and hydroxylamic acids for the treatment of infections
AU2001231137A1 (en)	2001-08-07	Treatment of neuropsychiatric disease with protease and neuraminidase inhibitors
GB9613488D0 (en)	1996-08-28	HIV protease inhibitors useful in the treatment of aids
YU40098A (en)	1999-09-27	The use of olanzapine in preparation of medicine
ID15808A (en)	1997-08-07	USE OF PROTEASE IN THE MEDICINE
EE9800260A (en)	2000-06-15	A drug for the treatment and prophylaxis of HIV and AIDS
FI20001454A0 (en)	2000-06-19	Procedure for improving the robotic telephone and reminder features of the telephone set