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FI960516L - Substituerade bifenylsulfonamidendotelinantagonister - Google Patents

Substituerade bifenylsulfonamidendotelinantagonister Download PDF

Info

Publication number
FI960516L
FI960516L FI960516A FI960516A FI960516L FI 960516 L FI960516 L FI 960516L FI 960516 A FI960516 A FI 960516A FI 960516 A FI960516 A FI 960516A FI 960516 L FI960516 L FI 960516L
Authority
FI
Finland
Prior art keywords
dientothelin
biphenylsulfonamide
antagonists
substituted
substituted biphenylsulfonamide
Prior art date
Application number
FI960516A
Other languages
English (en)
Finnish (fi)
Other versions
FI960516A0 (sv
FI960516A7 (sv
Inventor
Natesan Murugesan
Joel C Barrish
Philip D Stein
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/384,066 external-priority patent/US5760038A/en
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of FI960516A0 publication Critical patent/FI960516A0/sv
Publication of FI960516L publication Critical patent/FI960516L/sv
Publication of FI960516A7 publication Critical patent/FI960516A7/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI960516A 1995-02-06 1996-02-05 Substituerade bifenylsulfonamidendotelinantagonister FI960516A7 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/384,066 US5760038A (en) 1995-02-06 1995-02-06 Substituted biphenyl sulfonamide endothelin antagonists
SG1996000999A SG46218A1 (en) 1995-02-06 1996-02-06 Substituted biphenyl sulfonamide endothelin antagonists

Publications (3)

Publication Number Publication Date
FI960516A0 FI960516A0 (sv) 1996-02-05
FI960516L true FI960516L (sv) 1996-08-07
FI960516A7 FI960516A7 (sv) 1996-08-07

Family

ID=26665074

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960516A FI960516A7 (sv) 1995-02-06 1996-02-05 Substituerade bifenylsulfonamidendotelinantagonister

Country Status (11)

Country Link
EP (1) EP0725067A1 (sv)
JP (1) JPH08245600A (sv)
CN (1) CN1060172C (sv)
CA (1) CA2168154A1 (sv)
CZ (1) CZ29296A3 (sv)
FI (1) FI960516A7 (sv)
HU (1) HUP9600256A3 (sv)
IL (1) IL116916A (sv)
NO (1) NO305559B1 (sv)
PL (1) PL183283B1 (sv)
SG (1) SG46218A1 (sv)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962490A (en) 1987-09-25 1999-10-05 Texas Biotechnology Corporation Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
US6030991A (en) * 1993-05-20 2000-02-29 Texas Biotechnology Corp. Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US6376523B1 (en) 1994-05-20 2002-04-23 Texas Biotechnology Corporation Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US6613804B2 (en) 1993-05-20 2003-09-02 Encysive Pharmaceuticals, Inc. Biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin
US6342610B2 (en) 1993-05-20 2002-01-29 Texas Biotechnology Corp. N-aryl thienyl-, furyl-, and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
US6541498B2 (en) 1993-05-20 2003-04-01 Texas Biotechnology Benzenesulfonamides and the use thereof to modulate the activity of endothelin
US5612359A (en) * 1994-08-26 1997-03-18 Bristol-Myers Squibb Company Substituted biphenyl isoxazole sulfonamides
NZ306734A (sv) * 1995-04-04 2000-01-28 Texas Biotechnology Corp
US5846990A (en) * 1995-07-24 1998-12-08 Bristol-Myers Squibb Co. Substituted biphenyl isoxazole sulfonamides
JPH09124620A (ja) * 1995-10-11 1997-05-13 Bristol Myers Squibb Co 置換ビフェニルスルホンアミドエンドセリン拮抗剤
WO1997029747A1 (en) * 1996-02-20 1997-08-21 Bristol-Myers Squibb Company Methods for the preparation of biphenyl isoxazole sulfonamides
US5856507A (en) * 1997-01-21 1999-01-05 Bristol-Myers Squibb Co. Methods for the preparation of biphenyl isoxazole sulfonamides
US5939446A (en) * 1996-04-09 1999-08-17 Bristol-Myers Squibb Co. Heteroaryl substituted phenyl isoxazole sulfonamide endothelin antagonists
US5804585A (en) * 1996-04-15 1998-09-08 Texas Biotechnology Corporation Thieno-pyridine sulfonamides derivatives thereof and related compounds that modulate the activity of endothelin
AU6187898A (en) * 1997-01-30 1998-08-25 Bristol-Myers Squibb Company Method for preventing or treating low renin hypertension by administering an endothelin antagonist
TW536540B (en) * 1997-01-30 2003-06-11 Bristol Myers Squibb Co Endothelin antagonists: N-[[2'-[[(4,5-dimethyl-3-isoxazolyl)amino]sulfonyl]-4-(2-oxazolyl)[1,1'-biphenyl]-2-yl]methyl]-N,3,3-trimethylbutanamide and N-(4,5-dimethyl-3-isoxazolyl)-2'-[(3,3-dimethyl-2-oxo-1-pyrrolidinyl)methyl]-4'-(2-oxazolyl)[1,1'-biphe
US6030975A (en) * 1997-03-14 2000-02-29 Basf Aktiengesellschaft Carboxylic acid derivatives, their preparation and use in treating cancer
US5783705A (en) 1997-04-28 1998-07-21 Texas Biotechnology Corporation Process of preparing alkali metal salys of hydrophobic sulfonamides
NZ336898A (en) 1997-04-28 2001-10-26 Texas Biotechnology Corp Sulfonamides for treatment of endothelin-mediated disorders
CN1295477A (zh) * 1998-03-31 2001-05-16 田边制药株式会社 排尿困难的预防或治疗剂
CN1149196C (zh) * 1998-07-06 2004-05-12 布里斯托尔-迈尔斯斯奎布公司 作为血管紧张肽和内皮肽受体双重拮抗剂的联苯基磺酰胺
HUP0201320A2 (en) 1999-03-19 2002-08-28 Bristol Myers Squibb Co Methods for the preparation of biphenyl isoxazole sulfonamides and intermediates thereof
US6455554B1 (en) 1999-06-07 2002-09-24 Targacept, Inc. Oxopyridinyl pharmaceutical compositions and methods for use
US6639082B2 (en) 2000-10-17 2003-10-28 Bristol-Myers Squibb Company Methods for the preparation of biphenyl isoxazole sulfonamides
US9196844B2 (en) * 2012-06-01 2015-11-24 Semiconductor Energy Laboratory Co., Ltd. Method of synthesizing pyrazine derivative, and light-emitting element, light-emitting device, electronic device, and lighting device

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591761A (en) * 1993-05-20 1997-01-07 Texas Biotechnology Corporation Thiophenyl-, furyl-and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
NZ247440A (en) * 1992-05-06 1995-04-27 Squibb & Sons Inc Phenyl sulphonamide derivatives, preparation and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
CA2168154A1 (en) 1996-08-07
EP0725067A1 (en) 1996-08-07
HU9600256D0 (en) 1996-03-28
CN1138581A (zh) 1996-12-25
CZ29296A3 (en) 1996-09-11
JPH08245600A (ja) 1996-09-24
NO960473D0 (no) 1996-02-05
SG46218A1 (en) 1998-02-20
PL183283B1 (pl) 2002-06-28
FI960516A0 (sv) 1996-02-05
IL116916A0 (en) 1996-05-14
NO305559B1 (no) 1999-06-21
PL312650A1 (en) 1996-08-19
HUP9600256A2 (en) 1997-10-28
HUP9600256A3 (en) 1998-08-28
FI960516A7 (sv) 1996-08-07
CN1060172C (zh) 2001-01-03
IL116916A (en) 2000-09-28
NO960473L (no) 1996-08-07

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