[go: up one dir, main page]

FI953827L - Trisyklisiä pyratsolijohdannaisia - Google Patents

Trisyklisiä pyratsolijohdannaisia Download PDF

Info

Publication number
FI953827L
FI953827L FI953827A FI953827A FI953827L FI 953827 L FI953827 L FI 953827L FI 953827 A FI953827 A FI 953827A FI 953827 A FI953827 A FI 953827A FI 953827 L FI953827 L FI 953827L
Authority
FI
Finland
Prior art keywords
pyrazole derivatives
tricyclic pyrazole
tricyclic
derivatives
pyrazole
Prior art date
Application number
FI953827A
Other languages
English (en)
Swedish (sv)
Other versions
FI113264B (fi
FI953827A0 (fi
Inventor
Juergen Wichmann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI953827A0 publication Critical patent/FI953827A0/fi
Publication of FI953827L publication Critical patent/FI953827L/fi
Application granted granted Critical
Publication of FI113264B publication Critical patent/FI113264B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56Benzopyrazoles; Hydrogenated benzopyrazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Addiction (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
FI953827A 1994-08-12 1995-08-11 Trisyklisiä pyratsolijohdannaisia FI113264B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH249094 1994-08-12
CH249094 1994-08-12

Publications (3)

Publication Number Publication Date
FI953827A0 FI953827A0 (fi) 1995-08-11
FI953827L true FI953827L (fi) 1996-02-13
FI113264B FI113264B (fi) 2004-03-31

Family

ID=4234975

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953827A FI113264B (fi) 1994-08-12 1995-08-11 Trisyklisiä pyratsolijohdannaisia

Country Status (30)

Country Link
US (1) US5561150A (fi)
EP (1) EP0700905B1 (fi)
JP (1) JP2755560B2 (fi)
KR (1) KR100385384B1 (fi)
CN (1) CN1056607C (fi)
AT (1) ATE207905T1 (fi)
AU (1) AU691310B2 (fi)
BR (1) BR9503630A (fi)
CA (1) CA2153937C (fi)
CO (1) CO4410331A1 (fi)
CZ (1) CZ289027B6 (fi)
DE (1) DE59509777D1 (fi)
DK (1) DK0700905T3 (fi)
ES (1) ES2164730T3 (fi)
FI (1) FI113264B (fi)
HU (1) HUT72066A (fi)
IL (1) IL114849A (fi)
MA (1) MA23643A1 (fi)
MY (1) MY133619A (fi)
NO (1) NO305026B1 (fi)
NZ (1) NZ272731A (fi)
PE (1) PE34096A1 (fi)
PH (1) PH31424A (fi)
PL (1) PL182480B1 (fi)
PT (1) PT700905E (fi)
RU (1) RU2152388C1 (fi)
TR (1) TR199500977A2 (fi)
TW (1) TW403738B (fi)
UY (1) UY24016A1 (fi)
ZA (1) ZA956553B (fi)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU727654B2 (en) * 1997-06-13 2000-12-21 Yamanouchi Pharmaceutical Co., Ltd. Tricyclic pyrazole derivative
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
US6960579B1 (en) 1998-05-19 2005-11-01 Alcon Manufacturing, Ltd. Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
GB9819019D0 (en) 1998-09-01 1998-10-28 Cerebrus Ltd Chemical compounds II
GB9820767D0 (en) * 1998-09-23 1998-11-18 Cerebrus Ltd Chemical compounds VIII
GB9918965D0 (en) * 1999-08-11 1999-10-13 Cerebrus Ltd Chemical compounds xxi
GB9918962D0 (en) 1999-08-11 1999-10-13 Cerebrus Ltd Chemical compounds xxii
US20040048844A1 (en) * 1999-10-20 2004-03-11 Bristol-Myers Squibb Pharma Company Acylsemicarbazides as cyclin dependent kinase inhibitors useful as anti-cancer and anti-proliferative agents
US6291504B1 (en) * 1999-10-20 2001-09-18 Dupont Pharmaceuticals Company Acylsemicarbazides and their uses
EP1132389A1 (en) 2000-03-06 2001-09-12 Vernalis Research Limited New aza-indolyl derivatives for the treatment of obesity
JP2004538240A (ja) * 2000-03-31 2004-12-24 パーデュー・リサーチ・ファウンデーション ホスホラミデートおよびそのための方法
WO2004098807A1 (en) * 2000-11-21 2004-11-18 Barsplice Products, Inc. Method of making steel couplers for joining concrete reinforcing bars
HUP0303316A2 (hu) 2000-12-20 2004-01-28 Bristol-Myers Squibb Pharma Company Aril- és amino-aril-szubsztituált szerotoninreceptor agonista és antagonista ligandumok és ezeket tartalmazó gyógyszerkészítmények
EP1392658A4 (en) * 2001-06-01 2004-10-13 Alcon Inc NOVEL FUSED INDAZOLES AND INDOLES AND THEIR USE IN THE TREATMENT OF GLAUCOMES
ATE318821T1 (de) * 2001-06-01 2006-03-15 Alcon Inc Pyranoindazole und ihre verwendung in der glaukombehandlung
US6884816B2 (en) * 2001-08-31 2005-04-26 Alcon, Inc. Hydroxy substituted fused naphthyl-azoles and fused indeno-azoles and their use for the treatment of glaucoma
US20050080143A1 (en) * 2001-11-29 2005-04-14 Steiner Mitchell S. Treatment of androgen-deprivation induced osteoporosis
US20060269611A1 (en) * 2001-11-29 2006-11-30 Steiner Mitchell S Prevention and treatment of androgen-deprivation induced osteoporosis
US20070197664A1 (en) * 2001-11-29 2007-08-23 Steiner Mitchell S Prevention and treatment of androgen-deprivation induced osteoporosis
US20040214898A1 (en) * 2001-11-29 2004-10-28 Steiner Mitchell S. Methods for treating hot flashes
US20080249183A1 (en) * 2001-11-29 2008-10-09 Steiner Mitchell S Treatment of androgen-deprivation induced osteoporosis
TW593302B (en) * 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
US20050119489A1 (en) * 2001-12-28 2005-06-02 Ladouceur Gaetan H. 4-Sulfide/sulfoxide/sulfonyl-1h-pyrazolyl derivative compounds, for use in diseases associated with the 5-ht2c receptor
WO2003057161A2 (en) * 2001-12-28 2003-07-17 Bayer Pharmaceuticals Corporation BENZOTHIENO [3,2-c]PYRAZOLYL AND BENZOFURANO [3,2-c] PYRAZOLYL COMPOUNDS, THEIR USE IN DISEASES ASSOCIATED WITH THE 5-HT2C RECEPTOR AND INTERMEDIATE COMPOUNDS THEREOF
EP1465871A1 (en) * 2001-12-28 2004-10-13 Bayer Corporation Pyrazole derivatives for use in diseases associated with the 5-ht2c receptor
PL375564A1 (en) * 2002-08-30 2005-11-28 Alcon, Inc. Substituted 5-chroman-5-yl-ethylamine compounds and their use for the treatment of glaucoma
WO2004054572A2 (en) * 2002-12-13 2004-07-01 Alcon, Inc. Novel benzopyran analogs and their use for the treatment of glaucoma
WO2005053688A1 (en) * 2003-11-26 2005-06-16 Alcon, Inc. Substituted furo[2,3-g] indazoles for the treatment of glaucoma
US7129257B1 (en) 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
WO2005058911A2 (en) * 2003-12-15 2005-06-30 Alcon, Inc. Substituted [1,4]oxazino[2,3-g]indazoles for the treatment of glaucoma
FR2870239B1 (fr) * 2004-05-11 2006-06-16 Sanofi Synthelabo Derives de carbamate de 2h- ou 3h-benzo[e]indazol-1-yle, leur preparation et leur application en therapeutique.
WO2006062839A1 (en) * 2004-12-08 2006-06-15 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
TW200744567A (en) * 2005-09-23 2007-12-16 Alcon Inc Phenylethylamine analogs and their use for treating glaucoma
US20070293475A1 (en) * 2006-06-20 2007-12-20 Alcon Manufacturing Ltd. Aryl and heteroaryl tetrahydrobenzazepine derivatives and their use for treating glaucoma

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US392430A (en) * 1888-11-06 Tubular lantern
GB1228792A (fi) * 1967-07-20 1971-04-21
BE789948A (fr) * 1971-10-13 1973-04-11 Sandoz Sa Nouveaux derives du pyrazole, leur preparation et leur application comme medicaments
US3957816A (en) * 1973-01-31 1976-05-18 Sandoz, Inc. Substituted naphtho pyrazoles
SU1676453A3 (ru) * 1987-09-18 1991-09-07 Фармиталиа Карло Эрба С.Р.Л.(Фирма) Способ получени конденсированных производных пиразола или их фармацевтически приемлемых солей

Also Published As

Publication number Publication date
TW403738B (en) 2000-09-01
TR199500977A2 (tr) 1996-06-21
IL114849A (en) 1999-11-30
PH31424A (en) 1998-10-29
BR9503630A (pt) 1996-05-28
KR960007568A (ko) 1996-03-22
CO4410331A1 (es) 1997-01-09
MA23643A1 (fr) 1996-04-01
IL114849A0 (en) 1995-12-08
AU691310B2 (en) 1998-05-14
DK0700905T3 (da) 2002-02-18
DE59509777D1 (de) 2001-12-06
KR100385384B1 (ko) 2003-09-19
JPH0859623A (ja) 1996-03-05
EP0700905A1 (de) 1996-03-13
NO305026B1 (no) 1999-03-22
PE34096A1 (es) 1996-10-04
NO953162D0 (no) 1995-08-11
HK1012342A1 (zh) 1999-07-30
CN1056607C (zh) 2000-09-20
PT700905E (pt) 2002-04-29
ATE207905T1 (de) 2001-11-15
UY24016A1 (es) 2000-12-29
CZ289027B6 (cs) 2001-10-17
PL309974A1 (en) 1996-02-19
US5561150A (en) 1996-10-01
RU2152388C1 (ru) 2000-07-10
NO953162L (no) 1996-02-13
PL182480B1 (pl) 2002-01-31
JP2755560B2 (ja) 1998-05-20
CA2153937C (en) 2007-04-10
MY133619A (en) 2007-11-30
CZ9502013A3 (en) 1996-03-13
CA2153937A1 (en) 1996-02-13
NZ272731A (en) 1996-09-25
HUT72066A (en) 1996-03-28
EP0700905B1 (de) 2001-10-31
ZA956553B (en) 1996-02-12
AU2838295A (en) 1996-02-22
ES2164730T3 (es) 2002-03-01
FI113264B (fi) 2004-03-31
CN1131666A (zh) 1996-09-25
FI953827A0 (fi) 1995-08-11

Similar Documents

Publication Publication Date Title
FI953827L (fi) Trisyklisiä pyratsolijohdannaisia
EE9900211A (et) Asendatud pürasooliderivaadid
NO20012219D0 (no) Tricykliske pyrazolderivater
ATE302192T1 (de) Trizyklische pyrol- oder pyrazolderivate
ATE360618T1 (de) Pyrazolderivate
FI954829L (fi) Aroyylipiperidiinijohdannaiset
NO952854D0 (no) 1-arylpyrimidin-derivater
FI971234A7 (fi) Imidatsolijohdannainen
DE59508427D1 (de) 3-aryl-4-hydroxy-delta 3 -dihydrothiophenon-derivate
DE122009000076I1 (de) Chinazolin-derivate
DE69719547D1 (de) Parasitizide pyrazolderivate
FI955783L (fi) Pyrrolijohdannaisia
ATE199150T1 (de) Diphenylmethylenpiperidin-derivate
EP0708091A3 (en) Indoloyl-guanidines derivatives
FI962892A7 (fi) Pyrrolopyridatsiinin johdannaiset
DE69430587D1 (de) Pyrimidin-acyclonukleosid-derivate
FI971227L (fi) Pyramidinyylipyratsolijohdannaisia
ATA100695A (de) Prothrombin-derivate
FI932928A7 (fi) Uudet bentsodiatsepiinijohdokset
FI945989A0 (fi) Uusi bentsodiatsepiinijohdannainen
FI960367L (fi) Uusia dialkoksipyridinyylibentsimidatsolijohdannaisia
ATE239018T1 (de) Pyrazol-derivate
ATE240307T1 (de) Diarylalkenylamin-derivate
DE69527786D1 (de) Diaminomethyliden-derivate
FI964853A7 (fi) Deasetoksitaksolijohdannaiset

Legal Events

Date Code Title Description
MA Patent expired