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FI953106A7 - Difuoripentapeptidijohdannaiset anti-inflammatorisina aineina - Google Patents

Difuoripentapeptidijohdannaiset anti-inflammatorisina aineina Download PDF

Info

Publication number
FI953106A7
FI953106A7 FI953106A FI953106A FI953106A7 FI 953106 A7 FI953106 A7 FI 953106A7 FI 953106 A FI953106 A FI 953106A FI 953106 A FI953106 A FI 953106A FI 953106 A7 FI953106 A7 FI 953106A7
Authority
FI
Finland
Prior art keywords
difluoropentapeptide
derivatives
inflammatory agents
inflammatory
agents
Prior art date
Application number
FI953106A
Other languages
English (en)
Swedish (sv)
Other versions
FI953106A0 (fi
Inventor
John Mcmillan Mciver
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of FI953106A0 publication Critical patent/FI953106A0/fi
Publication of FI953106A7 publication Critical patent/FI953106A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI953106A 1992-12-22 1995-06-21 Difuoripentapeptidijohdannaiset anti-inflammatorisina aineina FI953106A7 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99521792A 1992-12-22 1992-12-22
PCT/US1993/012349 WO1994014842A1 (en) 1992-12-22 1993-12-16 Difluoro-pentapeptide derivative anti-inflammatory agents

Publications (2)

Publication Number Publication Date
FI953106A0 FI953106A0 (fi) 1995-06-21
FI953106A7 true FI953106A7 (fi) 1995-07-13

Family

ID=25541529

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953106A FI953106A7 (fi) 1992-12-22 1995-06-21 Difuoripentapeptidijohdannaiset anti-inflammatorisina aineina

Country Status (22)

Country Link
US (1) US5760002A (fi)
EP (1) EP0675901A1 (fi)
JP (1) JPH08505143A (fi)
KR (1) KR950704350A (fi)
CN (1) CN1056615C (fi)
AU (1) AU697299B2 (fi)
BR (1) BR9307728A (fi)
CA (1) CA2152267C (fi)
CZ (1) CZ286126B6 (fi)
FI (1) FI953106A7 (fi)
HU (1) HUT72977A (fi)
IL (1) IL108031A0 (fi)
MX (1) MX9400072A (fi)
NO (1) NO952485L (fi)
NZ (1) NZ259274A (fi)
PE (1) PE5195A1 (fi)
PL (1) PL177914B1 (fi)
RU (1) RU2141971C1 (fi)
SG (1) SG54306A1 (fi)
SK (1) SK82795A3 (fi)
TW (1) TW402607B (fi)
WO (1) WO1994014842A1 (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003002845A (ja) * 2001-04-03 2003-01-08 Univ Nihon 哺乳類の硬組織治療用組成物及びその治療方法
EP1554572B1 (en) 2001-07-25 2009-10-14 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
JP2008539047A (ja) 2005-04-28 2008-11-13 プロテウス バイオメディカル インコーポレイテッド ファーマインフォーマティックスシステム
KR20090071598A (ko) 2006-09-18 2009-07-01 랩터 파마슈티컬 인코포레이티드 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료
PT2398500T (pt) 2009-02-20 2019-06-14 2 Bbb Medicines B V Sistema de entrega de medicamentos à base de glutationas
CN102458374A (zh) 2009-05-06 2012-05-16 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1980000252A1 (en) * 1978-07-18 1980-02-21 Kabi Ab Bradykinin-inhibiting tripeptide derivatives
HU177098B (en) * 1979-01-04 1981-07-28 Gyogyszerkutato Intezet Process for producing new peptidyl-n-carboxy-l-arginin-a
JPS5754157A (en) * 1980-09-19 1982-03-31 Nippon Kayaku Co Ltd L-argininal derivative and its preparation
HU184368B (en) * 1981-01-13 1984-08-28 Gyogyszerkutato Intezet Process for preparing d-phenyl-alanyl-l-propyl-l-arginine-ald ehyde-shulphate
JPS5830300B2 (ja) * 1981-11-02 1983-06-28 三菱化学株式会社 トリペプチドおよびその誘導体の製造法
JPS58164563A (ja) * 1982-03-25 1983-09-29 Dai Ichi Pure Chem Co Ltd 新規ペプチドアルデヒド類及びその製造法
WO1984000365A1 (en) * 1982-07-19 1984-02-02 Nat Res Dev Synthetic peptides and their preparation
CS231228B1 (en) * 1982-10-01 1984-10-15 Evzen Kasafirek Biologically effective tri and tetrapeptide alkylamide derivatives and their processing method
EP0124317B1 (en) * 1983-04-27 1990-04-11 Ici Americas Inc. Proline derivatives
CA1267499A (en) * 1983-07-12 1990-04-03 Cedric H. Hassall Peptide amides and aldehydes
US4816449A (en) * 1984-08-09 1989-03-28 Immunetech Pharmaceuticals Immunotherapeutic anti-inflammatory peptide agents
US4845242A (en) * 1987-04-28 1989-07-04 Georgia Tech Research Corporation Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents
HU192646B (en) * 1984-12-21 1987-06-29 Gyogyszerkutato Intezet Process for preparing new n-alkyl-peptide aldehydes
CA1341029C (en) * 1985-02-04 2000-06-20 Michael Kolb Peptidase inhibitors
US5066643A (en) * 1985-02-19 1991-11-19 Sandoz Ltd. Fluorine and chlorine statine or statone containing peptides and method of use
CH672792A5 (fi) * 1985-02-19 1989-12-29 Sandoz Ag
DE3674131D1 (de) * 1985-04-19 1990-10-18 Upjohn Co Substituierte dihalo-statin-reninhemmungsmittel.
ATE71934T1 (de) * 1985-06-07 1992-02-15 Ici America Inc Selektionierte difluorverbindungen.
WO1987002675A1 (en) * 1985-11-01 1987-05-07 Pfizer Inc. Difluorocyclostatine containing polypeptides
GB8613704D0 (en) * 1986-06-05 1986-07-09 Ici America Inc Difluoro keto compounds
GB8613703D0 (en) * 1986-06-05 1986-07-09 Ici America Inc Difluoro peptide compounds
NZ223148A (en) * 1987-01-16 1989-10-27 Merrell Dow Pharma Peptide derivatives having peptidase inhibition activity
US5187157A (en) * 1987-06-05 1993-02-16 Du Pont Merck Pharmaceutical Company Peptide boronic acid inhibitors of trypsin-like proteases
JPH075634B2 (ja) * 1987-10-30 1995-01-25 日東紡績株式会社 トリペプチド類及びこれを含有する抗プラスミン剤
US4902781A (en) * 1987-11-24 1990-02-20 Taisho Pharmaceutical Co., Ltd. Novel tripetide derivatives
US5036054A (en) * 1988-02-11 1991-07-30 Warner-Lambert Company Renin inhibitors containing alpha-heteroatom amino acids
IL90872A0 (en) * 1988-07-08 1990-02-09 Smithkline Beckman Corp Retroviral protease binding peptides
YU30589A (en) * 1989-02-09 1991-10-31 Imunoloski Z Zagreb New adamantyl containing tripeptides and it's hydrochloride and process for preparing and use
GB8910547D0 (en) * 1989-05-08 1989-06-21 Ici America Inc Substituted ketones
US5177060A (en) * 1990-01-09 1993-01-05 Regents Of The University Of California Anti-inflammatory peptides and treatment to inhibit vascular leakage in injured tissues

Also Published As

Publication number Publication date
FI953106A0 (fi) 1995-06-21
MX9400072A (es) 1994-08-31
PE5195A1 (es) 1995-03-08
EP0675901A1 (en) 1995-10-11
US5760002A (en) 1998-06-02
HU9501844D0 (en) 1995-08-28
HUT72977A (en) 1996-06-28
WO1994014842A1 (en) 1994-07-07
TW402607B (en) 2000-08-21
NO952485D0 (no) 1995-06-21
PL309638A1 (en) 1995-10-30
KR950704350A (ko) 1995-11-20
SK82795A3 (en) 1995-12-06
RU2141971C1 (ru) 1999-11-27
NO952485L (no) 1995-08-22
BR9307728A (pt) 1999-08-31
IL108031A0 (en) 1994-04-12
CA2152267C (en) 2001-04-17
CA2152267A1 (en) 1994-07-07
SG54306A1 (en) 1998-11-16
RU95113497A (ru) 1997-06-10
AU5803994A (en) 1994-07-19
CN1056615C (zh) 2000-09-20
CZ286126B6 (cs) 2000-01-12
CZ164595A3 (en) 1995-12-13
PL177914B1 (pl) 2000-01-31
CN1095072A (zh) 1994-11-16
NZ259274A (en) 1997-10-24
AU697299B2 (en) 1998-10-01
JPH08505143A (ja) 1996-06-04

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