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FI952578L - Lämpörakeistusmenetelmä - Google Patents

Lämpörakeistusmenetelmä Download PDF

Info

Publication number
FI952578L
FI952578L FI952578A FI952578A FI952578L FI 952578 L FI952578 L FI 952578L FI 952578 A FI952578 A FI 952578A FI 952578 A FI952578 A FI 952578A FI 952578 L FI952578 L FI 952578L
Authority
FI
Finland
Prior art keywords
granulation method
thermal granulation
thermal
granulation
Prior art date
Application number
FI952578A
Other languages
English (en)
Swedish (sv)
Other versions
FI952578A7 (fi
FI952578A0 (fi
Inventor
Ingrid Huerner
Peter Danz
Reinhard Walter
Joachim Maasz
Georg Frank
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of FI952578A0 publication Critical patent/FI952578A0/fi
Publication of FI952578L publication Critical patent/FI952578L/fi
Publication of FI952578A7 publication Critical patent/FI952578A7/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/06Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of pills, lozenges or dragees
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J2200/00General characteristics or adaptations
    • A61J2200/20Extrusion means, e.g. for producing pharmaceutical forms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Glanulating (AREA)
  • Seasonings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Container Filling Or Packaging Operations (AREA)
  • Circuit Arrangement For Electric Light Sources In General (AREA)
  • Amplifiers (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Processing And Handling Of Plastics And Other Materials For Molding In General (AREA)
FI952578A 1994-05-30 1995-05-26 Lämpörakeistusmenetelmä FI952578A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4418837A DE4418837A1 (de) 1994-05-30 1994-05-30 Thermisches Granulierverfahren

Publications (3)

Publication Number Publication Date
FI952578A0 FI952578A0 (fi) 1995-05-26
FI952578L true FI952578L (fi) 1995-12-01
FI952578A7 FI952578A7 (fi) 1995-12-01

Family

ID=6519322

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952578A FI952578A7 (fi) 1994-05-30 1995-05-26 Lämpörakeistusmenetelmä

Country Status (16)

Country Link
US (1) US5667807A (fi)
EP (1) EP0686392B1 (fi)
JP (1) JPH0847521A (fi)
KR (1) KR950031043A (fi)
AT (1) ATE173919T1 (fi)
AU (1) AU693877B2 (fi)
CA (1) CA2150304A1 (fi)
CO (1) CO4290345A1 (fi)
DE (2) DE4418837A1 (fi)
DK (1) DK0686392T3 (fi)
ES (1) ES2124460T3 (fi)
FI (1) FI952578A7 (fi)
MX (1) MX193007B (fi)
NO (1) NO952110L (fi)
SI (1) SI0686392T1 (fi)
SV (1) SV1995000023A (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE19509805A1 (de) * 1995-03-21 1996-09-26 Basf Ag Transparente, schnell freisetzende Zubereitungen von nichtsteroidalen Analgetica
DE19602206A1 (de) 1996-01-23 1997-07-24 Basf Ag Zubereitungen nichtsteroidaler Analgetika
DE19721467A1 (de) 1997-05-22 1998-11-26 Basf Ag Verfahren zur Herstellung kleinteiliger Zubereitungen biologisch aktiver Stoffe
CA2214895C (en) * 1997-09-19 1999-04-20 Bernard Charles Sherman Improved pharmaceutical composition comprising fenofibrate
US6547997B1 (en) * 1997-11-28 2003-04-15 Abbot Laboratories Method for producing solvent-free noncrystalline biologically active substances
US6197347B1 (en) 1998-06-29 2001-03-06 Andrx Pharmaceuticals, Inc. Oral dosage for the controlled release of analgesic
DE19918325A1 (de) * 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
NZ519485A (en) * 1999-12-09 2004-02-27 Boots Co Plc Compressed tablet composition comprising a solidified melt granule of NSAID and silicon dioxide as an extra granular component
NZ535261A (en) * 2000-08-08 2004-12-24 Smithkline Beecham P A tablet comprising the hydrochloride salt of N-(1-nbutyl-4-piperidinyl)methyl]-3,4-[1,3]oxazino[3,2-a] indole-10-carboxamide
EP1252886A1 (en) * 2001-04-27 2002-10-30 Universiteit Gent Controlled release pharmaceutical pellet compositions
US6761905B2 (en) * 2001-05-01 2004-07-13 Wei Ming Pharmaceutical Mfg. Co., Ltd. Process for the preparation of direct tabletting formulations and aids
GB0113839D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
GB0113841D0 (en) * 2001-06-07 2001-08-01 Boots Co Plc Therapeutic agents
MXPA04007857A (es) * 2002-02-14 2004-10-15 Glaxo Group Ltd Composicion farmaceutica que comprende n-((1-butil -4-piperidinil) metil)-3, 4-dihidro-2h -(1, 3)oxazino (3, 2-a)indol -10-carboxamida o sal de la misma, y procedimiento para la misma que comprende granulacion en seco.
BRPI0407181A (pt) * 2003-02-03 2006-02-07 Novartis Ag Formulação farmacêutica
US20040265378A1 (en) * 2003-06-25 2004-12-30 Yingxu Peng Method and compositions for producing granules containing high concentrations of biologically active substances
GB0519350D0 (en) * 2005-09-22 2005-11-02 Boots Healthcare Int Ltd Therapeutic agents
US20140163109A1 (en) 2012-03-26 2014-06-12 Glatt Ag Taste-masked ibupropen granules
RU2706727C2 (ru) 2014-09-17 2019-11-20 Стирлайф Индия Прайвит Лимитед Шипучие композиции и способы их получения и применения
US11219594B2 (en) * 2015-12-12 2022-01-11 Steerlife India Private Limited Effervescent compositions of metformin and processes for preparation thereof
GB201801415D0 (en) * 2018-01-29 2018-03-14 Univ Limerick Method and apparatus

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE463541B (sv) * 1987-08-31 1990-12-10 Lejus Medical Ab Granulaer produkt oeverdragen av en smaelta av sig sjaelv samt foerfarande foer dess framstaellning
DE3833448A1 (de) 1988-10-01 1990-04-12 Hoechst Ag Verfahren zur gewinnung von ibuprofen fuer die direkttablettierung
US5169645A (en) * 1989-10-31 1992-12-08 Duquesne University Of The Holy Ghost Directly compressible granules having improved flow properties
DE4031881C2 (de) * 1990-10-08 1994-02-24 Sanol Arznei Schwarz Gmbh Lösungsmittelfreie, oral zu verabreichende pharmazeutische Zubereitung mit verzögerter Wirkstoffreisetzung und Verfahren zu deren Herstellung
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
US5403593A (en) * 1991-03-04 1995-04-04 Sandoz Ltd. Melt granulated compositions for preparing sustained release dosage forms

Also Published As

Publication number Publication date
JPH0847521A (ja) 1996-02-20
NO952110L (no) 1995-12-01
MX193007B (en) 1999-08-13
CA2150304A1 (en) 1995-12-01
EP0686392A1 (de) 1995-12-13
ES2124460T3 (es) 1999-02-01
ATE173919T1 (de) 1998-12-15
SV1995000023A (es) 1996-04-11
DK0686392T3 (da) 1999-08-16
DE4418837A1 (de) 1995-12-07
KR950031043A (ko) 1995-12-18
SI0686392T1 (en) 1999-04-30
US5667807A (en) 1997-09-16
NO952110D0 (no) 1995-05-29
FI952578A7 (fi) 1995-12-01
AU2027795A (en) 1995-12-07
CO4290345A1 (es) 1996-04-17
FI952578A0 (fi) 1995-05-26
EP0686392B1 (de) 1998-12-02
AU693877B2 (en) 1998-07-09
DE59504386D1 (de) 1999-01-14

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