FI952022L - Biologiset tekijät ja neuraaliset kantasolut - Google Patents

Biologiset tekijät ja neuraaliset kantasolut Download PDF

Info

Publication number: FI952022L
Authority: FI; Finland
Prior art keywords: stem cells; neural stem; biological factors; biological; factors
Prior art date: 1992-10-28

Application number

FI952022A

Other languages

English (en)

Swedish (sv)

Other versions

FI952022A7 (fi

FI952022A0 (fi

Inventor

Samuel Weiss

Brent A Reynolds

Joseph P Hammang

Edward E Baetge

Original Assignee

Neurospheres Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-10-28

Filing date

1993-10-27

Publication date

1995-04-27

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25513066&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI952022(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1993-10-27 Application filed by Neurospheres Ltd filed Critical Neurospheres Ltd

1995-04-27 Publication of FI952022L publication Critical patent/FI952022L/fi

1995-04-27 Publication of FI952022A7 publication Critical patent/FI952022A7/fi

1995-04-27 Publication of FI952022A0 publication Critical patent/FI952022A0/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0623—Stem cells
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y402/00—Carbon-oxygen lyases (4.2)
- C12Y402/01—Hydro-lyases (4.2.1)
- C12Y402/01011—Phosphopyruvate hydratase (4.2.1.11), i.e. enolase
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/20—Transition metals
- C12N2500/24—Iron; Fe chelators; Transferrin
- C12N2500/25—Insulin-transferrin; Insulin-transferrin-selenium
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/30—Organic components
- C12N2500/46—Amines, e.g. putrescine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/11—Epidermal growth factor [EGF]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/148—Transforming growth factor alpha [TGF-a]
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/30—Hormones
- C12N2501/38—Hormones with nuclear receptors
- C12N2501/39—Steroid hormones
- C12N2501/392—Sexual steroids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
General Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Microbiology (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Developmental Biology & Embryology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Cell Biology (AREA)
Oncology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

FI952022A 1992-10-28 1993-10-27 Biologiset tekijät ja neuraaliset kantasolut FI952022A0 (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US96762292A	1992-10-28	1992-10-28
PCT/CA1993/000456 WO1994010292A1 (en)	1992-10-28	1993-10-27	Biological factors and neural stem cells

Publications (3)

Publication Number	Publication Date
FI952022L true FI952022L (fi)	1995-04-27
FI952022A7 FI952022A7 (fi)	1995-04-27
FI952022A0 FI952022A0 (fi)	1995-04-27

Family

ID=25513066

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI952022A FI952022A0 (fi)	1992-10-28	1993-10-27	Biologiset tekijät ja neuraaliset kantasolut

Country Status (14)

Country	Link
EP (2)	EP1298202B1 (fi)
JP (2)	JPH08502652A (fi)
KR (1)	KR950704476A (fi)
AT (2)	ATE234353T1 (fi)
AU (2)	AU5367694A (fi)
CA (1)	CA2148138C (fi)
DE (2)	DE69332759T3 (fi)
DK (1)	DK0669973T4 (fi)
ES (1)	ES2194016T5 (fi)
FI (1)	FI952022A0 (fi)
NO (1)	NO324412B1 (fi)
PT (1)	PT669973E (fi)
RU (1)	RU95115822A (fi)
WO (1)	WO1994010292A1 (fi)

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US5849553A (en) *	1992-07-27	1998-12-15	California Institute Of Technology	Mammalian multipotent neural stem cells
US6872699B2 (en)	1992-11-13	2005-03-29	Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften, E.V.	Truncated Flk-1 receptor protein, methods of use and a recombinant vector containing a nucleotide encoding the truncated Flk-1 protein
US6001654A (en) *	1994-01-28	1999-12-14	California Institute Of Technology	Methods for differentiating neural stem cells to neurons or smooth muscle cells using TGT-β super family growth factors
AU3338595A (en) *	1994-07-29	1996-03-04	Dalhousie University	Propagation and inducible differentiation of human fetal central nervous system progenitor cells
JPH10505754A (ja) *	1994-09-23	1998-06-09	ニューロスフィアーズホウルディングスリミテッド	Ｃｎｓ機能及び機能障害インビトロモデル
AU716811B2 (en) *	1994-11-14	2000-03-09	Neurospheres Holdings Ltd	Regulation of neural stem cell proliferation
HUP9900243A2 (hu) *	1995-05-24	1999-05-28	Cellfactors Plc	Sejtdifferenciálódást befolyásoló hatóanyagok
FR2746109B1 (fr)	1996-03-12	1998-04-17	Rhone Poulenc Rorer Sa	Milieu pour la conservation de materiel biologique
US5753506A (en) *	1996-05-23	1998-05-19	Cns Stem Cell Technology, Inc.	Isolation propagation and directed differentiation of stem cells from embryonic and adult central nervous system of mammals
US7544511B2 (en)	1996-09-25	2009-06-09	Neuralstem Biopharmaceuticals Ltd.	Stable neural stem cell line methods
US6969608B1 (en)	1996-08-26	2005-11-29	Mcgill University	Pharmaceuticals containing multipotential precursor cells from tissues containing sensory receptors
US6787355B1 (en)	1996-08-26	2004-09-07	Mcgill University	Multipotent neural stem cells from peripheral tissues and uses thereof
US6713247B1 (en)	1996-09-03	2004-03-30	Signal Pharmaceuticials, Inc.	Human CNS cell lines and methods of use therefor
CA2216439A1 (en) *	1996-09-25	1998-03-25	Derek Van Der Kooy	Pharmaceuticals containing retinal stem cells
KR20060002033A (ko) *	1997-07-04	2006-01-06	유니버시티 오브 유타 리서치 파운데이션	계통이 예정된 신경세포 전구체
US20020123143A1 (en)	1997-08-22	2002-09-05	Jean Toma	Multipotent stem cells from peripheral tissues and uses thereof
US5968829A (en)	1997-09-05	1999-10-19	Cytotherapeutics, Inc.	Human CNS neural stem cells
US6165783A (en) *	1997-10-24	2000-12-26	Neuro Spheres Holdings Ltd.	Erythropoietin-mediated neurogenesis
US6787356B1 (en)	1998-07-24	2004-09-07	The United States Of America As Represented By The Department Of Health And Human Services	Cell expansion system for use in neural transplantation
JP3291698B2 (ja) *	1998-07-24	2002-06-10	スティーブン・カーティン	可変眼鏡用レンズ
EP1109887A4 (en) *	1998-07-29	2003-05-21	Layton Bioscience Inc	PRODUCTION AND USE OF DOPAMINERGIC CELLS TO TREAT DOPAMINERGIC DEFICIENCIES
SE9804064D0 (sv) *	1998-11-25	1998-11-25	A & Science Invest Ab	Medicinal product and method for treatment of conditions affecting neural stem cells or progenitor cells
US6291516B1 (en)	1999-01-13	2001-09-18	Curis, Inc.	Regulators of the hedgehog pathway, compositions and uses related thereto
AU7263300A (en) *	1999-09-16	2001-04-17	Neurotrophic Bioscience, Inc.	Opaminergic neuronal survival-promoting factors and uses thereof
WO2001029206A1 (en)	1999-10-15	2001-04-26	Advanced Cell Technology, Inc.	Methods of producing differentiated progenitor cells and lineage-defective embryonic stem cells
US7544509B2 (en)	2000-01-24	2009-06-09	Mcgill University	Method for preparing stem cell preparations
EP1261357B1 (en)	2000-02-11	2010-07-14	The Schepens Eye Research Institute, Inc.	Isolation and transplantation of retinal stem cells
US6613798B1 (en)	2000-03-30	2003-09-02	Curis, Inc.	Small organic molecule regulators of cell proliferation
US8852937B2 (en)	2000-03-30	2014-10-07	Curis, Inc.	Small organic molecule regulators of cell proliferation
US7115653B2 (en)	2000-03-30	2006-10-03	Curis, Inc.	Small organic molecule regulators of cell proliferation
US6683108B1 (en)	2000-03-30	2004-01-27	Curis, Inc.	Agonists of hedgehog signaling pathways and uses related thereto
US20020114788A1 (en) *	2000-07-27	2002-08-22	Ole Isacson	Cell implantation therapy for neurological diseases or disorders
US6908732B2 (en)	2000-10-13	2005-06-21	President & Fellows Of Harvard College	Compounds and methods for regulating cell differentiation
US7048934B2 (en)	2001-08-30	2006-05-23	Stem Cell Therapeutics Inc.	Combined regulation of neural cell production
AR036401A1 (es)	2001-09-14	2004-09-08	Stem Cell Therapeutics Inc	Incremento de la cantidad de celulas madre neuronales inducido por prolactina.
EP2266396A3 (en)	2001-09-24	2011-06-15	Sangamo BioSciences, Inc.	Modulation of stem cells using zinc finger proteins
EP1464698A4 (en) *	2001-12-13	2006-04-12	Japan Science & Tech Agency	HUMAN CELL CULTURE MEDIUM AND CULTIVATION PROCESS
AU2003216058A1 (en)	2002-01-14	2003-07-30	The Board Of Trustees Of The University Of Illinois	Mammalian neural stem cells, compositions and uses thereof
KR20040084911A (ko)	2002-02-15	2004-10-06	코넬 리서치 파운데이션 인코포레이티드	희소돌기아교세포 선조 세포를 이용한 선천적으로미엘린화되지 않은 전뇌의 미엘린화
US7655674B2 (en)	2002-04-22	2010-02-02	The Johns Hopkins University	Modulators of hedgehog signaling pathways, compositions and uses related thereto
AU2003250697B2 (en) *	2002-07-30	2008-05-01	Stem Cell Therapeutics Inc.	Oligodendrocyte production from multipotent neural stem cells
US7368115B2 (en)	2002-07-31	2008-05-06	Stem Cell Therapeutics Inc.	Method of enhancing neural stem cell proliferation, differentiation, and survival using pituitary adenylate cyclase activating polypeptide (PACAP)
AU2003296316A1 (en)	2002-12-09	2004-06-30	The Mclean Hospital Corporation	Dopaminergic neurons differentiated from embryonic cells for treating neurodegenerative diseases
US8293488B2 (en)	2002-12-09	2012-10-23	Neuralstem, Inc.	Method for screening neurogenic agents
EP1576134B1 (en)	2002-12-09	2013-03-06	Judith Kelleher-Andersson	Method for discovering neurogenic agents
US7459152B2 (en)	2003-04-23	2008-12-02	Rush University Medical Center	Erythropoietin administration to improve graft survival
CN1867678B (zh)	2003-09-12	2012-10-03	干细胞技术公司	神经集落形成分析
CA2547827C (en) *	2003-12-02	2015-02-03	Catholic Healthcare West	Compositions and methods for propagation of neural progenitor cells
US20070269412A1 (en)	2003-12-02	2007-11-22	Celavie Biosciences, Llc	Pluripotent cells
CA2556266A1 (en)	2004-02-13	2005-08-25	Stem Cell Therapeutics Corp.	Use of luteinizing hormone (lh), and chorionic gonadotropin (hcg) for proliferation of neural stem cells and neurogenesis
CN101084303A (zh)	2004-11-17	2007-12-05	神经干公司	用于治疗神经变性症状的人类神经细胞的移植
EP1928488A4 (en)	2005-09-27	2009-07-22	Stem Cell Therapeutics Corp	REGULATION OF OLIGODENDROCYTE PRECURSOR CELL PROLIFERATION WITH PROLACTIN
EP2004211A4 (en)	2006-03-17	2010-07-07	Stem Cell Therapeutics Corp	DOSEERSCHEMATA FOR LH OR HCG AND EPO FOR THE TREATMENT OF NEUROLOGICAL DISEASES
US20110218176A1 (en)	2006-11-01	2011-09-08	Barbara Brooke Jennings-Spring	Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
JP2008220205A (ja) *	2007-03-09	2008-09-25	Sumitomo Bakelite Co Ltd	神経幹細胞凝集塊形成用容器、その製造方法、及び神経幹細胞凝集塊の作成方法。
US8945919B2 (en) *	2007-08-15	2015-02-03	San Bio, Inc.	Methods and composition for treating neural degeneration
EP2283116B1 (en)	2008-05-08	2016-09-28	University Of Rochester	Treating myelin diseases with optimized cell preparations
EP3187581A1 (en)	2008-12-23	2017-07-05	BOCO Silicon Valley, Inc.	Target populations of oligodendrocyte precursor cells and methods of making and using same
EP2380972B1 (en)	2010-04-19	2012-09-19	Technische Universität Dresden	Methods and compositions for the expansion of somatic stem cells and progenitor cells
WO2012016049A1 (en)	2010-07-28	2012-02-02	Neuralstem, Inc.	Methods for treating and/or reversing neurodegenerative diseases and/or disorders
JP5867797B2 (ja) *	2011-05-27	2016-02-24	国立大学法人京都大学	ドーパミン産生神経の分化誘導用の細胞培養基材
US10865383B2 (en)	2011-07-12	2020-12-15	Lineage Cell Therapeutics, Inc.	Methods and formulations for orthopedic cell therapy
EP2814947B1 (en)	2012-02-17	2018-11-21	Schepens Eye Research Institute	Phenotype profile of human retinal progenitor cells
WO2014124087A1 (en)	2013-02-06	2014-08-14	University Of Rochester	Induced pluripotent cell-derived oligodendrocyte progenitor cells for the treatment of myelin disorders
CA2964927C (en)	2014-10-20	2019-07-30	Neuralstem, Inc.	Stable neural stem cells comprising an exogenous polynucleotide coding for a growth factor and methods of use thereof
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WO2017075271A1 (en) *	2015-10-29	2017-05-04	The Regents Of The University Of Claifornia	Astrocyte differentiation protocol
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NZ226750A (en) *	1987-10-29	1990-09-26	Amrad Corp Ltd	Immortalisation of neural precursor cells by introducing a retrovirus vector containing a myc-oncogene
AU6174490A (en) *	1989-08-04	1991-03-11	Board Of Regents, The University Of Texas System	Methods and compositions; purified preparation of neural progenitor regulatory factor
ATE240389T1 (de) *	1991-07-08	2003-05-15	Neurospheres Holdings Ltd	Auf wachstumsfaktoren reagierende neurale vorläuferzellen, die in vitro vermehrt werden können.

1993
- 1993-10-27 FI FI952022A patent/FI952022A0/fi unknown
- 1993-10-27 PT PT93923994T patent/PT669973E/pt unknown
- 1993-10-27 AT AT93923994T patent/ATE234353T1/de active
- 1993-10-27 DE DE69332759T patent/DE69332759T3/de not_active Expired - Lifetime
- 1993-10-27 EP EP02018736A patent/EP1298202B1/en not_active Expired - Lifetime
- 1993-10-27 EP EP93923994A patent/EP0669973B9/en not_active Expired - Lifetime
- 1993-10-27 DK DK93923994T patent/DK0669973T4/da active
- 1993-10-27 ES ES93923994T patent/ES2194016T5/es not_active Expired - Lifetime
- 1993-10-27 WO PCT/CA1993/000456 patent/WO1994010292A1/en not_active Ceased
- 1993-10-27 AT AT02018736T patent/ATE483795T1/de not_active IP Right Cessation
- 1993-10-27 JP JP6510503A patent/JPH08502652A/ja not_active Withdrawn
- 1993-10-27 AU AU53676/94A patent/AU5367694A/en not_active Abandoned
- 1993-10-27 DE DE69334344T patent/DE69334344D1/de not_active Expired - Lifetime
- 1993-10-27 CA CA002148138A patent/CA2148138C/en not_active Expired - Fee Related
- 1993-10-27 KR KR1019950701608A patent/KR950704476A/ko not_active Ceased
1995
- 1995-04-27 NO NO19951617A patent/NO324412B1/no unknown
- 1995-05-26 RU RU95115822/13A patent/RU95115822A/ru unknown
1997
- 1997-12-24 AU AU49241/97A patent/AU703729B2/en not_active Ceased
2006
- 2006-10-10 JP JP2006276639A patent/JP2007014352A/ja active Pending

Also Published As

Publication number	Publication date
ATE234353T1 (de)	2003-03-15
AU703729B2 (en)	1999-04-01
DK0669973T3 (da)	2003-07-14
WO1994010292A1 (en)	1994-05-11
EP0669973A1 (en)	1995-09-06
NO951617D0 (no)	1995-04-27
DK0669973T4 (da)	2007-08-27
JPH08502652A (ja)	1996-03-26
EP1298202B1 (en)	2010-10-06
RU95115822A (ru)	1997-03-20
EP0669973B1 (en)	2003-03-12
PT669973E (pt)	2003-06-30
ATE483795T1 (de)	2010-10-15
ES2194016T5 (es)	2007-11-16
EP0669973B2 (en)	2007-04-18
EP0669973B9 (en)	2007-10-10
FI952022A7 (fi)	1995-04-27
NO324412B1 (no)	2007-10-08
CA2148138A1 (en)	1994-05-11
DE69332759T3 (de)	2008-01-24
ES2194016T3 (es)	2003-11-16
EP1298202A3 (en)	2003-12-03
FI952022A0 (fi)	1995-04-27
CA2148138C (en)	2002-01-08
JP2007014352A (ja)	2007-01-25
DE69334344D1 (de)	2010-11-18
NO951617L (no)	1995-04-27
AU5367694A (en)	1994-05-24
DE69332759D1 (de)	2003-04-17
DE69332759T2 (de)	2003-10-16
KR950704476A (ko)	1995-11-20
EP1298202A2 (en)	2003-04-02
AU4924197A (en)	1998-03-12

Publication	Publication Date	Title
FI952022L (fi)	1995-04-27	Biologiset tekijät ja neuraaliset kantasolut
FI951677L (fi)	1995-04-07	Remyelinaatio käyttäen neuraalisia kantasoluja
FI953569L (fi)	1995-09-25	Neuraalisten kantasolujen geneettinen modifikaatio
FI961855L (fi)	1996-06-04	Hermostojärjestelmään kuuluvien kantasolujen manipulointi ja modifiointi
DE3685762D1 (de)	1992-07-30	3-aryluracile und deren verwendung zur unkrautbekaempfung.
DE68921469D1 (de)	1995-04-06	Peptidderivate und deren verwendung.
DE69322573D1 (de)	1999-01-28	Zellkultureinsatz
DE69319983D1 (de)	1998-09-03	Zellkultureinsatz
DK0474748T3 (da)	1995-05-01	Biologisk klapprotese
DE68928978D1 (de)	1999-06-02	Neuronarchitektur
DE59309352D1 (de)	1999-03-11	Multicistronische expressionseinheiten und deren verwendung
FI945625A7 (fi)	1994-11-29	Indolokarbatsoli-imidit ja niiden käyttö
EP0690871A4 (en)	1999-10-20	GROWTH DIFFERENTIATION FACTOR-5
FI960635L (fi)	1996-02-12	Elektrodi ja sen valmistus
FI894980A7 (fi)	1990-05-19	Säiliö ja säiliön kansi
NO982350D0 (no)	1998-05-22	Stamcellefaktor
DE69620270D1 (de)	2002-05-02	Backfett und dessen Verwendung
KR880700194A (ko)	1988-02-20	콘테이너 밸브 및 콘테이너
DE69007952D1 (de)	1994-05-11	Biologische insektenbekaempfungsmittel und dessen verwendung.
DE59010528D1 (de)	1996-11-14	Pigmentzubereitungen und deren Verwendung
DE68910113D1 (de)	1993-11-25	Wachstuminhibierendes mittel und dessen verwendung.
DE69314293D1 (de)	1997-11-06	Neuronalanlage und -Bauverfahren
DE3688864D1 (de)	1993-09-16	L-phenylalanindehydrogenase und deren verwendung.
ATA213188A (de)	1989-12-15	Wasserverduennbare lufttrocknende beschichtungsmittel und deren verwendung
DE3688369D1 (de)	1993-06-03	Nodulationsfoerdernde bakterien und ihre verwendung.