FI951966A7 - Novel polyene compounds, pharmaceutical and cosmetic compositions containing them and their use - Google Patents

Novel polyene compounds, pharmaceutical and cosmetic compositions containing them and their use Download PDF

Info

Publication number: FI951966A7
Authority: FI; Finland
Prior art keywords: pharmaceutical; compositions containing; cosmetic compositions; polyene compounds; novel polyene
Prior art date: 1994-04-26

Application number

FI951966A

Other languages

Finnish (fi)

Swedish (sv)

Other versions

FI951966A0 (en

FI951966L (en

Inventor

Jean-Michel Bernardon

Philippe Nedoncelle

Original Assignee

Centre International De Rech Dermatologiques Galderma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-26

Filing date

1995-04-25

Publication date

1995-10-27

1995-04-25 Application filed by Centre International De Rech Dermatologiques Galderma filed Critical Centre International De Rech Dermatologiques Galderma

1995-04-25 Publication of FI951966A0 publication Critical patent/FI951966A0/en

1995-10-27 Publication of FI951966A7 publication Critical patent/FI951966A7/en

1995-10-27 Publication of FI951966L publication Critical patent/FI951966L/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/42—Amides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/54—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings and other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/62—Unsaturated compounds containing ether groups, groups, groups, or groups containing rings other than six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/72—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings and other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/734—Ethers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/92—Oral administration
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Epidemiology (AREA)
Birds (AREA)
Emergency Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Physical Education & Sports Medicine (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Dermatology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Orthopedic Medicine & Surgery (AREA)
Rheumatology (AREA)
Cosmetics (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Peptides Or Proteins (AREA)
Medicinal Preparation (AREA)

FI951966A 1994-04-26 1995-04-25 Novel polyene compounds, pharmaceutical and cosmetic compositions containing them and their use FI951966L (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9405017A FR2719041B1 (en)	1994-04-26	1994-04-26	New polyene compounds, pharmaceutical and cosmetic compositions containing them and uses.

Publications (3)

Publication Number	Publication Date
FI951966A0 FI951966A0 (en)	1995-04-25
FI951966A7 true FI951966A7 (en)	1995-10-27
FI951966L FI951966L (en)	1995-10-27

Family

ID=9462510

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI951966A FI951966L (en)	1994-04-26	1995-04-25	Novel polyene compounds, pharmaceutical and cosmetic compositions containing them and their use

Country Status (21)

Country	Link
US (2)	US5705167A (en)
EP (1)	EP0679628B1 (en)
JP (1)	JP2653992B2 (en)
KR (1)	KR100191818B1 (en)
AT (1)	ATE165332T1 (en)
AU (1)	AU674269B2 (en)
BR (1)	BR9501614A (en)
CA (1)	CA2147806C (en)
DE (1)	DE69502130T2 (en)
ES (1)	ES2119325T3 (en)
FI (1)	FI951966L (en)
FR (1)	FR2719041B1 (en)
GR (1)	GR3026700T3 (en)
HU (1)	HU218612B (en)
IL (1)	IL113473A0 (en)
MX (1)	MX9501848A (en)
NO (1)	NO303493B1 (en)
NZ (1)	NZ270865A (en)
PL (1)	PL180746B1 (en)
RU (1)	RU2121995C1 (en)
ZA (1)	ZA952973B (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7655699B1 (en)	1992-04-22	2010-02-02	Eisai Inc.	Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors
US6083977A (en) *	1994-12-30	2000-07-04	Ligand Pharmaceuticals Incorporated	Trienoic retinoid compounds and methods
AU712187B2 (en) *	1994-12-30	1999-10-28	Ligand Pharmaceuticals Incorporated	Novel trienoic retinoid compounds and methods
US7115728B1 (en)	1995-01-30	2006-10-03	Ligand Pharmaceutical Incorporated	Human peroxisome proliferator activated receptor γ
BR9610875A (en) *	1995-10-06	1999-07-13	Ligand Pharm Inc	Selective rxr modules - dimers and processes for your use
FR2755011B1 (en) *	1996-10-31	1998-11-20	Cird Galderma	USE OF INHIBITORS OF RETINOIC ACID ACTIVITY TO TREAT SENSITIVE SKIN AND / OR ACUTE DAMAGE INDUCED BY U.V. RADIATION
US5998654A (en) *	1997-07-25	1999-12-07	Ligand Pharmaceuticals Incorporated	Retinoic acid receptor antagonist compounds and methods
WO1999005161A1 (en) *	1997-07-25	1999-02-04	Ligand Pharmaceuticals Incorporated	HUMAN PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA (PPARη) GENE REGULATORY SEQUENCES AND USES THEREFOR
EP1030662B1 (en) *	1997-11-12	2006-08-02	F. Hoffmann-La Roche Ag	Treatment of t-helper cell type 2 mediated immune diseases with retinoid antagonists
US6326397B1 (en)	1998-11-10	2001-12-04	Hoffman-La Roche Inc.	Retinoid antagonists and use thereof
DE69915128D1 (en)	1998-12-17	2004-04-01	Hoffmann La Roche	7-ARYL-6 (Z) HEPTATRIC ACID RETINAMIDE AS APOPTOSIS INDUCING COMPOUNDS AND THEIR USE AS ANTICROBIAL AGENTS
KR20010113037A (en) *	1999-03-08	2001-12-24	추후기재	Retinoid antagonists and use thereof
US6566372B1 (en) *	1999-08-27	2003-05-20	Ligand Pharmaceuticals Incorporated	Bicyclic androgen and progesterone receptor modulator compounds and methods
JP2003508397A (en)	1999-08-27	2003-03-04	リガンド・ファーマシューティカルズ・インコーポレイテッド	8-Substituted-6-trifluoromethyl-9-pyrido [3,2-G] quinoline compounds as androgen receptor modulators
CN1391576A (en)	1999-08-27	2003-01-15	利甘德药品公司	Androgen receptor modulator compounds and methods
PE20010647A1 (en) *	1999-09-14	2001-06-23	Lilly Co Eli	RETINOID X RECEPTOR MODULATORS (RXR) WITH IMPROVED PHARMACOLOGICAL PROFILE
US7842727B2 (en) *	2001-03-27	2010-11-30	Errant Gene Therapeutics, Llc	Histone deacetylase inhibitors
US8026280B2 (en)	2001-03-27	2011-09-27	Errant Gene Therapeutics, Llc	Histone deacetylase inhibitors
US7312247B2 (en)	2001-03-27	2007-12-25	Errant Gene Therapeutics, Llc	Histone deacetylase inhibitors
US6495719B2 (en) *	2001-03-27	2002-12-17	Circagen Pharmaceutical	Histone deacetylase inhibitors
US20030124174A1 (en) *	2001-10-25	2003-07-03	Endo Pharmaceuticals, Inc	Method for treating non-neuropathic pain
WO2003099272A1 (en) *	2002-05-22	2003-12-04	Errant Gene Therapeutics, Llc	Histone deacetylase inhibitors based on alpha-ketoepoxide compounds
RU2248202C2 (en) *	2002-09-26	2005-03-20	Субоч Георгий Анатольевич	Antifungal preparation
CA2506504A1 (en) *	2002-11-20	2004-06-03	Errant Gene Therapeutics, Llc	Treatment of lung cells with histone deacetylase inhibitors
US20060160902A1 (en) *	2004-11-08	2006-07-20	Wiech Norbert L	Histone deacetylase inhibitors
FR2910320B1 (en)	2006-12-21	2009-02-13	Galderma Res & Dev S N C Snc	EMULSION COMPRISING AT LEAST ONE RETINOID AND BENZOLE PEROXIDE
FR2910321B1 (en)	2006-12-21	2009-07-10	Galderma Res & Dev S N C Snc	CREAM GEL COMPRISING AT LEAST ONE RETINOID AND BENZOLE PEROXIDE
FR2931661B1 (en)	2008-05-30	2010-07-30	Galderma Res & Dev	NOVEL DEPIGMENTING COMPOSITIONS IN THE FORM OF AN ANHYDROUS VASELIN - FREE AND ELASTOMER - FREE COMPOSITION COMPRISING A SOLUBILIZED PHENOLIC DERIVATIVE AND A RETINOID.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3882157A (en) *	1972-07-27	1975-05-06	Zoecon Corp	Thiolesters of phenylheptadienoic acids
US4201727A (en) *	1976-11-14	1980-05-06	Hoffmann-La Roche Inc.	Fluorinated aromatic polyenes
LU77254A1 (en) *	1977-05-04	1979-01-18
DE4036779A1 (en) *	1990-11-17	1992-05-21	Basf Ag	USE OF ARYLPOLYCAN CARBONIC ACIDS AND THEIR DERIVATIVES AS LIGHT PROTECTION AGENTS IN COSMETIC PREPARATIONS
CA2129773C (en) *	1993-09-02	2007-05-01	Michael Klaus	Aromatic carboxylic acid derivatives

1994
- 1994-04-26 FR FR9405017A patent/FR2719041B1/en not_active Expired - Fee Related
1995
- 1995-03-29 EP EP95400700A patent/EP0679628B1/en not_active Expired - Lifetime
- 1995-03-29 DE DE69502130T patent/DE69502130T2/en not_active Expired - Fee Related
- 1995-03-29 AT AT95400700T patent/ATE165332T1/en not_active IP Right Cessation
- 1995-03-29 ES ES95400700T patent/ES2119325T3/en not_active Expired - Lifetime
- 1995-04-04 NZ NZ270865A patent/NZ270865A/en unknown
- 1995-04-11 ZA ZA952973A patent/ZA952973B/en unknown
- 1995-04-18 AU AU16511/95A patent/AU674269B2/en not_active Ceased
- 1995-04-19 MX MX9501848A patent/MX9501848A/en unknown
- 1995-04-24 NO NO951543A patent/NO303493B1/en not_active IP Right Cessation
- 1995-04-24 IL IL11347395A patent/IL113473A0/en unknown
- 1995-04-25 RU RU95106674A patent/RU2121995C1/en not_active IP Right Cessation
- 1995-04-25 CA CA002147806A patent/CA2147806C/en not_active Expired - Fee Related
- 1995-04-25 BR BR9501614A patent/BR9501614A/en not_active IP Right Cessation
- 1995-04-25 PL PL95308342A patent/PL180746B1/en not_active IP Right Cessation
- 1995-04-25 HU HU9501169A patent/HU218612B/en not_active IP Right Cessation
- 1995-04-25 JP JP7101511A patent/JP2653992B2/en not_active Expired - Fee Related
- 1995-04-25 FI FI951966A patent/FI951966L/en not_active IP Right Cessation
- 1995-04-26 US US08/429,492 patent/US5705167A/en not_active Ceased
- 1995-04-26 KR KR1019950009987A patent/KR100191818B1/en not_active Expired - Fee Related
1998
- 1998-04-23 GR GR980400763T patent/GR3026700T3/en unknown
2000
- 2000-01-05 US US09/477,662 patent/USRE37947E1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR950029244A (en)	1995-11-22
JPH08104653A (en)	1996-04-23
RU95106674A (en)	1996-12-27
FR2719041B1 (en)	1996-05-31
HU218612B (en)	2000-10-28
CA2147806A1 (en)	1995-10-27
US5705167A (en)	1998-01-06
FI951966A0 (en)	1995-04-25
EP0679628A1 (en)	1995-11-02
FR2719041A1 (en)	1995-10-27
MX9501848A (en)	1997-02-28
DE69502130T2 (en)	1998-08-13
NO951543D0 (en)	1995-04-24
DE69502130D1 (en)	1998-05-28
JP2653992B2 (en)	1997-09-17
ES2119325T3 (en)	1998-10-01
KR100191818B1 (en)	1999-06-15
NZ270865A (en)	1996-11-26
FI951966L (en)	1995-10-27
GR3026700T3 (en)	1998-07-31
RU2121995C1 (en)	1998-11-20
HU9501169D0 (en)	1995-06-28
USRE37947E1 (en)	2002-12-31
NO951543L (en)	1995-10-27
IL113473A0 (en)	1995-07-31
PL308342A1 (en)	1995-10-30
AU1651195A (en)	1995-11-16
HUT74013A (en)	1996-10-28
AU674269B2 (en)	1996-12-12
CA2147806C (en)	2001-02-13
NO303493B1 (en)	1998-07-20
ZA952973B (en)	1995-12-19
BR9501614A (en)	1996-04-23
ATE165332T1 (en)	1998-05-15
PL180746B1 (en)	2001-04-30
EP0679628B1 (en)	1998-04-22

Publication	Publication Date	Title
FI951966A7 (en)	1995-10-27	Novel polyene compounds, pharmaceutical and cosmetic compositions containing them and their use
FI945882L (en)	1995-06-16	Novel biaromatic propynyl compounds, pharmaceutical and cosmetic compositions containing them and their use
FI973039A0 (en)	1997-07-17	Novel farnesyltransferase inhibitors, their preparation and pharmaceutical compositions containing them
FI973279A0 (en)	1997-08-08	Novel farnesyltransferase inhibitors, their preparation and pharmaceutical compositions containing them
FI964920A7 (en)	1996-12-09	Novel farnesyltransferase inhibitors, their preparation and pharmaceutical preparations containing them
FI934274A7 (en)	1993-09-29	N-sulfonyl-2-oxyindole derivatives, their preparation and pharmaceutical compositions containing them
NO954201L (en)	1996-04-26	Cosmetic composition
EE9500064A (en)	1996-06-17	Substituted 1H-imidazoles, methods for their preparation, and pharmaceutical compositions
FI953898L (en)	1996-02-20	Glycinamide derivatives, methods for their preparation and pharmaceutical compositions containing them
FI952550A7 (en)	1995-11-28	Novel N-pyridylcarboxamides and derivatives, processes for their preparation and pharmaceutical compositions containing them
FI951967A7 (en)	1995-10-27	Novel bicyclic aromatic compounds, pharmaceutical and cosmetic compositions containing them and their use
FI943688L (en)	1995-03-21	New 11-benzaldoxime-17beta-methoxy-27alpha-methoxy-methyl-estradiene derivatives, processes for their preparation and pharmaceutical compositions containing them
FI941836A7 (en)	1994-10-23	3-Deoxyoligosaccharides, methods for their preparation and pharmaceutical compositions containing them
FI951983L (en)	1995-10-27	New biaromatic acetylene compounds containing an adamantyl group, pharmaceutical and cosmetic compositions containing them and their use
FI972434A7 (en)	1997-06-09	Pharmaceutical composition containing lamotrigine
FI943645L (en)	1994-08-05	Novel baccatin-III and 10-deacetylbaccatin-III derivatives, their preparation and pharmaceutical compositions containing them
FI960316L (en)	1996-03-22	Oxathiolanes, process for their preparation and pharmaceutical compositions containing them
FI972757L (en)	1997-08-18	Hydroxyproline-rich proteins and pharmaceutical and cosmetic compositions containing them
BR9507768A (en)	1997-09-02	Pharmaceutical composition
FI964900A7 (en)	1996-12-05	New taxoids, their manufacture and pharmaceutical preparations containing them
FI971427L (en)	1997-05-26	Peptides and pharmaceutical compositions containing them
PT986537E (en)	2002-12-31	NEW HETERONETHYLENE COMPOUNDS AND PHARMACEUTICAL AND COSMETIC COMPOSITIONS CONTAINING THEM
FI964899A7 (en)	1996-12-05	New taxoids, their preparation and compositions containing them
FI951091A7 (en)	1995-09-12	Novel alkylaminoindan compounds, methods for their preparation and pharmaceutical compositions containing them
FI944751L (en)	1995-04-12	Heteroarylpiperidines, process for their preparation and pharmaceutical compositions containing them

Legal Events

Date	Code	Title	Description
2005-10-31	MA	Patent expired