FI950960L - Solid-phase synthesis of peptide alcohols - Google Patents
Solid-phase synthesis of peptide alcohols Download PDFInfo
- Publication number
- FI950960L FI950960L FI950960A FI950960A FI950960L FI 950960 L FI950960 L FI 950960L FI 950960 A FI950960 A FI 950960A FI 950960 A FI950960 A FI 950960A FI 950960 L FI950960 L FI 950960L
- Authority
- FI
- Finland
- Prior art keywords
- peptide
- alcohol
- solid
- phase synthesis
- peptide alcohols
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 150000001298 alcohols Chemical class 0.000 title 1
- 238000010532 solid phase synthesis reaction Methods 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 3
- 125000003158 alcohol group Chemical group 0.000 abstract 2
- DHKHKXVYLBGOIT-UHFFFAOYSA-N acetaldehyde Diethyl Acetal Natural products CCOC(C)OCC DHKHKXVYLBGOIT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002777 acetyl group Chemical class [H]C([H])([H])C(*)=O 0.000 abstract 1
- 238000005903 acid hydrolysis reaction Methods 0.000 abstract 1
- 210000004899 c-terminal region Anatomy 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000011347 resin Substances 0.000 abstract 1
- 229920005989 resin Polymers 0.000 abstract 1
- 125000003396 thiol group Chemical group [H]S* 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The invention relates to a process for preparing a peptide alcohol in which there are two alcohol groups, or an alcohol group and a thiol group, at the C-terminal end of the peptide chain, with the peptide alcohol being prepared, according to the invention, by performing an acid hydrolysis between the peptide alcohol and a resin acetal containing formylphenyl radicals.
Applications Claiming Priority (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3634825 | 1986-10-13 | ||
| DE3634797 | 1986-10-13 | ||
| DE3634826 | 1986-10-13 | ||
| DE3634826 | 1986-10-13 | ||
| DE3634797 | 1986-10-13 | ||
| DE3634825 | 1986-10-13 | ||
| DE3712626 | 1987-04-14 | ||
| DE3712626 | 1987-04-14 | ||
| CH315387 | 1987-08-17 | ||
| CH315387 | 1987-08-17 | ||
| FI874495 | 1987-10-12 | ||
| FI874495A FI874495L (en) | 1986-10-13 | 1987-10-12 | PEPTIDE DERIVATIVES. |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI950960L true FI950960L (en) | 1995-03-01 |
| FI950960A0 FI950960A0 (en) | 1995-03-01 |
| FI99113B FI99113B (en) | 1997-06-30 |
| FI99113C FI99113C (en) | 1997-10-10 |
Family
ID=27543710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI950960A FI99113C (en) | 1986-10-13 | 1995-03-01 | Synthesis of the solid phase of peptide alcohols |
Country Status (1)
| Country | Link |
|---|---|
| FI (1) | FI99113C (en) |
-
1995
- 1995-03-01 FI FI950960A patent/FI99113C/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI99113C (en) | 1997-10-10 |
| FI99113B (en) | 1997-06-30 |
| FI950960A0 (en) | 1995-03-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or assigment of application |
Owner name: NOVARTIS AG |
|
| BB | Publication of examined application | ||
| MA | Patent expired |