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FI950044L - Menetelmä proteiini C:n hajoamisen estämiseksi - Google Patents

Menetelmä proteiini C:n hajoamisen estämiseksi Download PDF

Info

Publication number
FI950044L
FI950044L FI950044A FI950044A FI950044L FI 950044 L FI950044 L FI 950044L FI 950044 A FI950044 A FI 950044A FI 950044 A FI950044 A FI 950044A FI 950044 L FI950044 L FI 950044L
Authority
FI
Finland
Prior art keywords
degradation
inhibiting protein
inhibiting
protein
Prior art date
Application number
FI950044A
Other languages
English (en)
Swedish (sv)
Other versions
FI115635B (fi
FI950044A0 (fi
Inventor
Jr Walter Francis Prouty
Josephine Secnik
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22650141&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI950044(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI950044A0 publication Critical patent/FI950044A0/fi
Publication of FI950044L publication Critical patent/FI950044L/fi
Application granted granted Critical
Publication of FI115635B publication Critical patent/FI115635B/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46Hydrolases (3)
    • A61K38/48Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482Serine endopeptidases (3.4.21)
    • A61K38/4866Protein C (3.4.21.69)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6464Protein C (3.4.21.69)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21069Protein C activated (3.4.21.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Diabetes (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
FI950044A 1994-01-05 1995-01-04 Menetelmiä proteiini C:n hajoamisen estämiseksi FI115635B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17783294A 1994-01-05 1994-01-05
US17783294 1994-01-05

Publications (3)

Publication Number Publication Date
FI950044A0 FI950044A0 (fi) 1995-01-04
FI950044L true FI950044L (fi) 1995-07-06
FI115635B FI115635B (fi) 2005-06-15

Family

ID=22650141

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950044A FI115635B (fi) 1994-01-05 1995-01-04 Menetelmiä proteiini C:n hajoamisen estämiseksi

Country Status (29)

Country Link
EP (2) EP0662513B1 (fi)
JP (1) JP3778588B2 (fi)
KR (1) KR950032287A (fi)
CN (1) CN1109891A (fi)
AT (1) ATE201045T1 (fi)
AU (1) AU1003195A (fi)
BR (1) BR9500017A (fi)
CA (1) CA2139468C (fi)
CO (1) CO4600680A1 (fi)
CZ (1) CZ1395A3 (fi)
DE (2) DE10299053I2 (fi)
DK (1) DK0662513T3 (fi)
ES (1) ES2156190T3 (fi)
FI (1) FI115635B (fi)
GR (1) GR3036277T3 (fi)
HU (1) HUT70465A (fi)
IL (1) IL112236A (fi)
LU (2) LU90992I2 (fi)
NL (1) NL300108I2 (fi)
NO (2) NO320157B1 (fi)
NZ (1) NZ270271A (fi)
PE (1) PE43995A1 (fi)
PL (1) PL180703B1 (fi)
PT (1) PT662513E (fi)
RU (1) RU2167936C2 (fi)
SI (1) SI0662513T1 (fi)
UA (1) UA39178C2 (fi)
YU (1) YU295A (fi)
ZA (1) ZA9514B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630137B1 (en) 1997-04-28 2003-10-07 Eli Lilly And Company Activated protein C formulations
US6162629A (en) * 1997-04-28 2000-12-19 Eli Lilly And Company Methods for processing activated protein C
EP1557463A1 (en) * 1997-04-28 2005-07-27 Eli Lilly & Company Improved methods for processing activated protein C
US7204981B2 (en) 2000-03-28 2007-04-17 Eli Lilly And Company Methods of treating diseases with activated protein C
JP2004511428A (ja) 2000-05-24 2004-04-15 イーライ・リリー・アンド・カンパニー 凝固亢進状態を処置するための製剤および方法
SG162834A1 (en) * 2006-07-14 2010-07-29 Genentech Inc Refolding of recombinant proteins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950513A (en) * 1965-12-03 1976-04-13 Novo Terapeutisk Laboratorium A/S Process of stabilizing therapeutically useful plasmin solutions
US3557002A (en) * 1967-11-15 1971-01-19 Procter & Gamble Stabilized aqueous enzyme preparation
GB2105521A (en) * 1981-08-12 1983-03-23 Univ Surrey Antenna
AT402262B (de) * 1991-06-20 1997-03-25 Immuno Ag Arzneimittel enthaltend aktiviertes protein c

Also Published As

Publication number Publication date
NO950018D0 (no) 1995-01-03
UA39178C2 (uk) 2001-06-15
CO4600680A1 (es) 1998-05-08
NO320157B1 (no) 2005-11-07
RU2167936C2 (ru) 2001-05-27
IL112236A0 (en) 1995-03-30
CA2139468C (en) 2007-08-21
DE69520844T2 (de) 2001-11-08
DE10299053I1 (de) 2003-05-22
KR950032287A (ko) 1995-12-20
JPH07206704A (ja) 1995-08-08
ZA9514B (en) 1996-07-03
LU90993I2 (fr) 2003-02-18
YU295A (sh) 1997-09-30
DE10299053I2 (de) 2004-04-01
HU9500021D0 (en) 1995-03-28
BR9500017A (pt) 1995-10-03
DE69520844D1 (de) 2001-06-13
RU95100178A (ru) 1997-03-27
PL180703B1 (pl) 2001-03-30
PE43995A1 (es) 1995-12-15
GR3036277T3 (en) 2001-10-31
ATE201045T1 (de) 2001-05-15
CA2139468A1 (en) 1995-07-06
AU1003195A (en) 1995-07-13
EP0662513B1 (en) 2001-05-09
IL112236A (en) 1999-12-31
SI0662513T1 (en) 2001-10-31
ES2156190T3 (es) 2001-06-16
LU90992I2 (fr) 2003-02-18
PT662513E (pt) 2001-08-30
NZ270271A (en) 1996-07-26
HUT70465A (en) 1995-10-30
CZ1395A3 (en) 1995-07-12
NO2006006I1 (no) 2006-05-15
NO950018L (no) 1995-07-06
EP1087011A3 (en) 2002-02-06
EP1087011A2 (en) 2001-03-28
NL300108I2 (nl) 2003-06-02
CN1109891A (zh) 1995-10-11
EP0662513A1 (en) 1995-07-12
FI115635B (fi) 2005-06-15
JP3778588B2 (ja) 2006-05-24
DK0662513T3 (da) 2001-05-28
NL300108I1 (nl) 2003-02-03
FI950044A0 (fi) 1995-01-04
PL306671A1 (en) 1995-07-10

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