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FI956273L - Optisesti aktiivinen bentsotiepiinijohdannainen, sen valmistus ja käyttö - Google Patents

Optisesti aktiivinen bentsotiepiinijohdannainen, sen valmistus ja käyttö Download PDF

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Publication number
FI956273L
FI956273L FI956273A FI956273A FI956273L FI 956273 L FI956273 L FI 956273L FI 956273 A FI956273 A FI 956273A FI 956273 A FI956273 A FI 956273A FI 956273 L FI956273 L FI 956273L
Authority
FI
Finland
Prior art keywords
preparation
optically active
active benzothiepine
benzothiepine derivative
derivative
Prior art date
Application number
FI956273A
Other languages
English (en)
Swedish (sv)
Other versions
FI956273A7 (fi
FI956273A0 (fi
Inventor
Takashi Sohda
Shigehisa Taketomi
Tsuneo Oda
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI956273A0 publication Critical patent/FI956273A0/fi
Publication of FI956273A7 publication Critical patent/FI956273A7/fi
Publication of FI956273L publication Critical patent/FI956273L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655363Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring
    • C07F9/655372Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/67Phosphorus compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657181Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
FI956273A 1994-12-28 1995-12-27 Optisesti aktiivinen bentsotiepiinijohdannainen, sen valmistus ja käyttö FI956273L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP32727594 1994-12-28

Publications (3)

Publication Number Publication Date
FI956273A0 FI956273A0 (fi) 1995-12-27
FI956273A7 FI956273A7 (fi) 1996-06-29
FI956273L true FI956273L (fi) 1996-06-29

Family

ID=18197308

Family Applications (1)

Application Number Title Priority Date Filing Date
FI956273A FI956273L (fi) 1994-12-28 1995-12-27 Optisesti aktiivinen bentsotiepiinijohdannainen, sen valmistus ja käyttö

Country Status (20)

Country Link
US (2) US6346521B1 (fi)
EP (1) EP0719782B1 (fi)
KR (1) KR960022542A (fi)
CN (1) CN1058718C (fi)
AR (1) AR002018A1 (fi)
AT (1) ATE202782T1 (fi)
AU (1) AU689004B2 (fi)
BR (1) BR9506098A (fi)
CA (1) CA2166152A1 (fi)
DE (1) DE69521595T2 (fi)
DK (1) DK0719782T3 (fi)
ES (1) ES2158034T3 (fi)
FI (1) FI956273L (fi)
GR (1) GR3036757T3 (fi)
HU (1) HUT74562A (fi)
NO (1) NO303641B1 (fi)
NZ (1) NZ280745A (fi)
PT (1) PT719782E (fi)
RU (1) RU2162083C2 (fi)
TW (1) TW403757B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2221784A1 (en) * 1995-06-05 1996-12-12 Takeda Chemical Industries, Ltd. Osteogenetic promoting pharmaceutical composition
US5910492A (en) * 1995-06-05 1999-06-08 Takeda Chemical Industries, Ltd. Osteogenic promoting pharmaceutical composition
WO1997003989A1 (en) * 1995-07-24 1997-02-06 Takeda Chemical Industries, Ltd. Production of optically active benzothiepin salts
ATE226078T1 (de) * 1996-08-26 2002-11-15 Takeda Chemical Industries Ltd Pharmazeutische zusammensetzung enthaltend ein osteogenese foerderndes mittel und ein polyethylen-glycol
AU4571097A (en) * 1996-10-09 1998-05-05 Takeda Chemical Industries Ltd. A method for producing a microparticle
AU4165699A (en) * 1998-06-15 2000-01-05 Takeda Chemical Industries Ltd. Composition for treating cartilage disease
CA2339662A1 (en) 1998-08-07 2000-02-17 Takeda Chemical Industries, Ltd. Benzothiepin derivatives, their production and use
CA2340165A1 (en) * 1998-08-12 2000-02-24 Haruhiko Makino Enhancer of cell differentiation induction factor
WO2000018444A1 (fr) * 1998-09-30 2000-04-06 Takeda Chemical Industries, Ltd. Compositions de materiaux de reparation des os/os artificiels
US6586434B2 (en) * 2000-03-10 2003-07-01 G.D. Searle, Llc Method for the preparation of tetrahydrobenzothiepines
IL159853A0 (en) * 2001-07-17 2004-06-20 Teva Pharma Dosage forms for immediate gastric release of a calcium transport stimulator coupled with delayed gastric release of a bis-phosphonate
US20050026871A1 (en) * 2002-07-17 2005-02-03 Moshe Flashner-Barak Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin D derivative
WO2005002590A1 (ja) * 2003-07-01 2005-01-13 Astellas Pharma Inc. 骨量増加誘導剤
US8152783B2 (en) * 2007-06-29 2012-04-10 Kci Licensing, Inc. Activation of bone and cartilage formation
RU2011134637A (ru) 2009-01-19 2013-02-27 Дайити Санкио Компани, Лимитед Циклическое соединение, содержащее гетероатом
SG175091A1 (en) 2009-04-06 2011-11-28 Daiichi Sankyo Co Ltd Cyclic compound having substituted phenyl group
BR112012026948A2 (pt) 2010-04-28 2019-09-24 Daiichi Sankyo Co Ltd composto, composição farmacêutica, e, métodos para melhorar o metabolismo ósseo, para previnir ou tratar uma doença associada com metabolismo ósseo e para previnir ou tratar osteoporose.
PL3040329T3 (pl) 2013-08-29 2019-04-30 Kyoto Pharma Ind Związek aromatyczny i jego zastosowanie w leczeniu chorób związanych z metabolizmem kości

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0138535A3 (en) * 1983-10-13 1987-01-28 British Telecommunications Plc Visual display logic simulation system
US5158943A (en) * 1988-11-21 1992-10-27 Takeda Chemical Industries, Ltd. Sulfur-containing heterocyclic compounds
DK656789A (da) 1988-12-28 1990-06-29 Takeda Chemical Industries Ltd Benzoheterocykliske forbindelser
EP0460488B1 (en) * 1990-05-30 2001-07-11 Takeda Chemical Industries, Ltd. Sulfur-containing heterocyclic compounds
JP3165866B2 (ja) * 1990-06-06 2001-05-14 武田薬品工業株式会社 含硫黄複素環化合物

Also Published As

Publication number Publication date
EP0719782A1 (en) 1996-07-03
FI956273A7 (fi) 1996-06-29
DE69521595D1 (de) 2001-08-09
NO955305D0 (no) 1995-12-27
CN1131669A (zh) 1996-09-25
US6346521B1 (en) 2002-02-12
AU4069395A (en) 1996-07-04
EP0719782B1 (en) 2001-07-04
AR002018A1 (es) 1998-01-07
DK0719782T3 (da) 2001-09-24
PT719782E (pt) 2001-10-31
US6632807B1 (en) 2003-10-14
GR3036757T3 (en) 2001-12-31
BR9506098A (pt) 1997-12-23
RU2162083C2 (ru) 2001-01-20
NZ280745A (en) 1997-09-22
KR960022542A (ko) 1996-07-18
HU9503802D0 (en) 1996-02-28
TW403757B (en) 2000-09-01
AU689004B2 (en) 1998-03-19
ATE202782T1 (de) 2001-07-15
FI956273A0 (fi) 1995-12-27
HUT74562A (en) 1997-01-28
ES2158034T3 (es) 2001-09-01
NO303641B1 (no) 1998-08-10
CA2166152A1 (en) 1996-06-29
DE69521595T2 (de) 2002-05-23
NO955305L (no) 1996-07-01
CN1058718C (zh) 2000-11-22

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