FI956273L - Optisesti aktiivinen bentsotiepiinijohdannainen, sen valmistus ja käyttö - Google Patents
Optisesti aktiivinen bentsotiepiinijohdannainen, sen valmistus ja käyttö Download PDFInfo
- Publication number
- FI956273L FI956273L FI956273A FI956273A FI956273L FI 956273 L FI956273 L FI 956273L FI 956273 A FI956273 A FI 956273A FI 956273 A FI956273 A FI 956273A FI 956273 L FI956273 L FI 956273L
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- optically active
- active benzothiepine
- benzothiepine derivative
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
- C07F9/655363—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring
- C07F9/655372—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/67—Phosphorus compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Rheumatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP32727594 | 1994-12-28 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI956273A0 FI956273A0 (fi) | 1995-12-27 |
| FI956273A7 FI956273A7 (fi) | 1996-06-29 |
| FI956273L true FI956273L (fi) | 1996-06-29 |
Family
ID=18197308
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI956273A FI956273L (fi) | 1994-12-28 | 1995-12-27 | Optisesti aktiivinen bentsotiepiinijohdannainen, sen valmistus ja käyttö |
Country Status (20)
| Country | Link |
|---|---|
| US (2) | US6346521B1 (fi) |
| EP (1) | EP0719782B1 (fi) |
| KR (1) | KR960022542A (fi) |
| CN (1) | CN1058718C (fi) |
| AR (1) | AR002018A1 (fi) |
| AT (1) | ATE202782T1 (fi) |
| AU (1) | AU689004B2 (fi) |
| BR (1) | BR9506098A (fi) |
| CA (1) | CA2166152A1 (fi) |
| DE (1) | DE69521595T2 (fi) |
| DK (1) | DK0719782T3 (fi) |
| ES (1) | ES2158034T3 (fi) |
| FI (1) | FI956273L (fi) |
| GR (1) | GR3036757T3 (fi) |
| HU (1) | HUT74562A (fi) |
| NO (1) | NO303641B1 (fi) |
| NZ (1) | NZ280745A (fi) |
| PT (1) | PT719782E (fi) |
| RU (1) | RU2162083C2 (fi) |
| TW (1) | TW403757B (fi) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2221784A1 (en) * | 1995-06-05 | 1996-12-12 | Takeda Chemical Industries, Ltd. | Osteogenetic promoting pharmaceutical composition |
| US5910492A (en) * | 1995-06-05 | 1999-06-08 | Takeda Chemical Industries, Ltd. | Osteogenic promoting pharmaceutical composition |
| WO1997003989A1 (en) * | 1995-07-24 | 1997-02-06 | Takeda Chemical Industries, Ltd. | Production of optically active benzothiepin salts |
| ATE226078T1 (de) * | 1996-08-26 | 2002-11-15 | Takeda Chemical Industries Ltd | Pharmazeutische zusammensetzung enthaltend ein osteogenese foerderndes mittel und ein polyethylen-glycol |
| AU4571097A (en) * | 1996-10-09 | 1998-05-05 | Takeda Chemical Industries Ltd. | A method for producing a microparticle |
| AU4165699A (en) * | 1998-06-15 | 2000-01-05 | Takeda Chemical Industries Ltd. | Composition for treating cartilage disease |
| CA2339662A1 (en) | 1998-08-07 | 2000-02-17 | Takeda Chemical Industries, Ltd. | Benzothiepin derivatives, their production and use |
| CA2340165A1 (en) * | 1998-08-12 | 2000-02-24 | Haruhiko Makino | Enhancer of cell differentiation induction factor |
| WO2000018444A1 (fr) * | 1998-09-30 | 2000-04-06 | Takeda Chemical Industries, Ltd. | Compositions de materiaux de reparation des os/os artificiels |
| US6586434B2 (en) * | 2000-03-10 | 2003-07-01 | G.D. Searle, Llc | Method for the preparation of tetrahydrobenzothiepines |
| IL159853A0 (en) * | 2001-07-17 | 2004-06-20 | Teva Pharma | Dosage forms for immediate gastric release of a calcium transport stimulator coupled with delayed gastric release of a bis-phosphonate |
| US20050026871A1 (en) * | 2002-07-17 | 2005-02-03 | Moshe Flashner-Barak | Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin D derivative |
| WO2005002590A1 (ja) * | 2003-07-01 | 2005-01-13 | Astellas Pharma Inc. | 骨量増加誘導剤 |
| US8152783B2 (en) * | 2007-06-29 | 2012-04-10 | Kci Licensing, Inc. | Activation of bone and cartilage formation |
| RU2011134637A (ru) | 2009-01-19 | 2013-02-27 | Дайити Санкио Компани, Лимитед | Циклическое соединение, содержащее гетероатом |
| SG175091A1 (en) | 2009-04-06 | 2011-11-28 | Daiichi Sankyo Co Ltd | Cyclic compound having substituted phenyl group |
| BR112012026948A2 (pt) | 2010-04-28 | 2019-09-24 | Daiichi Sankyo Co Ltd | composto, composição farmacêutica, e, métodos para melhorar o metabolismo ósseo, para previnir ou tratar uma doença associada com metabolismo ósseo e para previnir ou tratar osteoporose. |
| PL3040329T3 (pl) | 2013-08-29 | 2019-04-30 | Kyoto Pharma Ind | Związek aromatyczny i jego zastosowanie w leczeniu chorób związanych z metabolizmem kości |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0138535A3 (en) * | 1983-10-13 | 1987-01-28 | British Telecommunications Plc | Visual display logic simulation system |
| US5158943A (en) * | 1988-11-21 | 1992-10-27 | Takeda Chemical Industries, Ltd. | Sulfur-containing heterocyclic compounds |
| DK656789A (da) | 1988-12-28 | 1990-06-29 | Takeda Chemical Industries Ltd | Benzoheterocykliske forbindelser |
| EP0460488B1 (en) * | 1990-05-30 | 2001-07-11 | Takeda Chemical Industries, Ltd. | Sulfur-containing heterocyclic compounds |
| JP3165866B2 (ja) * | 1990-06-06 | 2001-05-14 | 武田薬品工業株式会社 | 含硫黄複素環化合物 |
-
1995
- 1995-12-20 TW TW084113629A patent/TW403757B/zh not_active IP Right Cessation
- 1995-12-21 NZ NZ280745A patent/NZ280745A/en unknown
- 1995-12-22 ES ES95120444T patent/ES2158034T3/es not_active Expired - Lifetime
- 1995-12-22 AU AU40693/95A patent/AU689004B2/en not_active Ceased
- 1995-12-22 DE DE69521595T patent/DE69521595T2/de not_active Expired - Fee Related
- 1995-12-22 PT PT95120444T patent/PT719782E/pt unknown
- 1995-12-22 EP EP95120444A patent/EP0719782B1/en not_active Expired - Lifetime
- 1995-12-22 AT AT95120444T patent/ATE202782T1/de not_active IP Right Cessation
- 1995-12-22 DK DK95120444T patent/DK0719782T3/da active
- 1995-12-27 FI FI956273A patent/FI956273L/fi unknown
- 1995-12-27 NO NO955305A patent/NO303641B1/no not_active IP Right Cessation
- 1995-12-27 RU RU95122478/04A patent/RU2162083C2/ru active
- 1995-12-27 CA CA002166152A patent/CA2166152A1/en not_active Abandoned
- 1995-12-27 HU HU9503802A patent/HUT74562A/hu unknown
- 1995-12-27 BR BR9506098A patent/BR9506098A/pt unknown
- 1995-12-28 KR KR1019950061545A patent/KR960022542A/ko not_active Ceased
- 1995-12-28 CN CN95121715A patent/CN1058718C/zh not_active Expired - Fee Related
- 1995-12-28 AR ARP950100805A patent/AR002018A1/es unknown
- 1995-12-28 US US08/579,731 patent/US6346521B1/en not_active Expired - Fee Related
-
2000
- 2000-08-09 US US09/635,067 patent/US6632807B1/en not_active Expired - Fee Related
-
2001
- 2001-09-28 GR GR20010401614T patent/GR3036757T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0719782A1 (en) | 1996-07-03 |
| FI956273A7 (fi) | 1996-06-29 |
| DE69521595D1 (de) | 2001-08-09 |
| NO955305D0 (no) | 1995-12-27 |
| CN1131669A (zh) | 1996-09-25 |
| US6346521B1 (en) | 2002-02-12 |
| AU4069395A (en) | 1996-07-04 |
| EP0719782B1 (en) | 2001-07-04 |
| AR002018A1 (es) | 1998-01-07 |
| DK0719782T3 (da) | 2001-09-24 |
| PT719782E (pt) | 2001-10-31 |
| US6632807B1 (en) | 2003-10-14 |
| GR3036757T3 (en) | 2001-12-31 |
| BR9506098A (pt) | 1997-12-23 |
| RU2162083C2 (ru) | 2001-01-20 |
| NZ280745A (en) | 1997-09-22 |
| KR960022542A (ko) | 1996-07-18 |
| HU9503802D0 (en) | 1996-02-28 |
| TW403757B (en) | 2000-09-01 |
| AU689004B2 (en) | 1998-03-19 |
| ATE202782T1 (de) | 2001-07-15 |
| FI956273A0 (fi) | 1995-12-27 |
| HUT74562A (en) | 1997-01-28 |
| ES2158034T3 (es) | 2001-09-01 |
| NO303641B1 (no) | 1998-08-10 |
| CA2166152A1 (en) | 1996-06-29 |
| DE69521595T2 (de) | 2002-05-23 |
| NO955305L (no) | 1996-07-01 |
| CN1058718C (zh) | 2000-11-22 |
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