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FI955316A7 - Vitamiini D:n amidijohdannaisia - Google Patents

Vitamiini D:n amidijohdannaisia

Info

Publication number
FI955316A7
FI955316A7 FI955316A FI955316A FI955316A7 FI 955316 A7 FI955316 A7 FI 955316A7 FI 955316 A FI955316 A FI 955316A FI 955316 A FI955316 A FI 955316A FI 955316 A7 FI955316 A7 FI 955316A7
Authority
FI
Finland
Prior art keywords
vitamin
amide derivatives
amide
derivatives
Prior art date
Application number
FI955316A
Other languages
English (en)
Swedish (sv)
Other versions
FI955316A0 (fi
FI112361B (fi
Inventor
Robert Henry Hesse
Sundara Katugam Srinivas Setty
Malathi Ramgopal
Original Assignee
Res Inst Medicine Chem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Res Inst Medicine Chem filed Critical Res Inst Medicine Chem
Publication of FI955316A0 publication Critical patent/FI955316A0/fi
Publication of FI955316A7 publication Critical patent/FI955316A7/fi
Application granted granted Critical
Publication of FI112361B publication Critical patent/FI112361B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215Radicals derived from nitrogen analogues of carbonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI955316A 1993-05-07 1995-11-06 Menetelmä terapeuttisesti käyttökelpoisten D-vitamiinin johdannaisten valmistamiseksi FI112361B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB939309422A GB9309422D0 (en) 1993-05-07 1993-05-07 Chemical compounds
GB9309422 1993-05-07
PCT/GB1994/000975 WO1994026707A1 (en) 1993-05-07 1994-05-06 Vitamin d amide derivatives
GB9400975 1994-05-06

Publications (3)

Publication Number Publication Date
FI955316A0 FI955316A0 (fi) 1995-11-06
FI955316A7 true FI955316A7 (fi) 1995-12-22
FI112361B FI112361B (fi) 2003-11-28

Family

ID=10735089

Family Applications (1)

Application Number Title Priority Date Filing Date
FI955316A FI112361B (fi) 1993-05-07 1995-11-06 Menetelmä terapeuttisesti käyttökelpoisten D-vitamiinin johdannaisten valmistamiseksi

Country Status (20)

Country Link
US (1) US5756733A (fi)
EP (1) EP0696275B1 (fi)
JP (1) JP3703099B2 (fi)
KR (1) KR100321414B1 (fi)
CN (1) CN1093852C (fi)
AT (1) ATE169617T1 (fi)
AU (1) AU678246B2 (fi)
CA (1) CA2162272A1 (fi)
CZ (1) CZ291238B6 (fi)
DE (1) DE69412476T2 (fi)
DK (1) DK0696275T3 (fi)
ES (1) ES2122275T3 (fi)
FI (1) FI112361B (fi)
GB (1) GB9309422D0 (fi)
HU (1) HUT74165A (fi)
IL (1) IL109595A (fi)
NO (1) NO309187B1 (fi)
NZ (1) NZ265665A (fi)
WO (1) WO1994026707A1 (fi)
ZA (1) ZA943162B (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9405715D0 (en) * 1994-03-23 1994-05-11 Res Inst Medicine Chem Chemical compounds
CA2342471C (en) * 1995-06-06 2002-10-29 Judith L. Treadway Heterocyclecarbonylmethyl amine intermediates
DE19619036A1 (de) * 1996-04-30 1997-11-13 Schering Ag Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
GB9623569D0 (en) * 1996-11-13 1997-01-08 Immunodiagnostic Systems Ltd Vitamin D immumoassay systems
US6043385A (en) * 1997-12-16 2000-03-28 Hoffman-La Roche Inc. Vitamin D derivatives
GB9804861D0 (en) * 1998-03-06 1998-04-29 Res Inst Medicine Chem Chemical compounds
EP1123921A4 (en) * 1998-10-23 2003-08-20 Teijin Ltd VITAMIN D 3 DERIVATIVES? AND MEDICINES FOR INFLAMMATORY RESPIRATORY DISEASES CONTAINING THEM
AU775904B2 (en) * 1999-02-08 2004-08-19 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
DE19935771A1 (de) * 1999-07-23 2001-02-01 Schering Ag Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
US6703380B2 (en) 1999-09-29 2004-03-09 Colotech A/S Prevention of cancer
PT1220676E (pt) 1999-09-29 2005-08-31 Coloctech As Prevencao do cancro colorrectal
US6989377B2 (en) 1999-12-21 2006-01-24 Wisconsin Alumni Research Foundation Treating vitamin D responsive diseases
US6358939B1 (en) 1999-12-21 2002-03-19 Northern Lights Pharmaceuticals, Llc Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
CN101462994B (zh) * 2000-06-15 2012-11-28 中外制药株式会社 维生素d衍生物
ATE509910T1 (de) * 2000-06-15 2011-06-15 Chugai Pharmaceutical Co Ltd Vitamin d derivate mit einem 22-oxa- oder 22-thia-atom, einer sauer-, ester- oder amid- substitutierten c17-seitenkette und einer 16(17)- doppelbindung
US6277877B1 (en) 2000-08-15 2001-08-21 Pfizer, Inc. Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors
RU2323926C2 (ru) * 2000-12-08 2008-05-10 Чугаи Сейяку Кабусики Кайся Способ карбонилирования
ATE413388T1 (de) * 2002-04-26 2008-11-15 Schering Corp Muskarin antagonisten
CA2653772C (en) 2006-06-02 2014-04-08 Nippon Shinyaku Co., Ltd. 9,10-secopregnane derivative and pharmaceutical
WO2009117831A1 (en) * 2008-03-27 2009-10-01 The Royal Institution For The Advancement Of Learning/Mcgill University Hybrid molecules having mixed vitamin d receptor agonism and histone deacetylase inhibitory properties
CA2981549A1 (en) 2009-01-27 2010-08-05 Berg Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
KR101880032B1 (ko) 2009-08-14 2018-07-20 베르그 엘엘씨 탈모증 치료용 비타민 d3 및 이의 유사체들
WO2012151058A1 (en) 2011-05-03 2012-11-08 Wisconsin Alumni Research Foundation (20s)-24-(p-toluenesulfonyloxy)-25,26,27-trinorvitamin d3 analogs and their uses
WO2012158794A1 (en) 2011-05-17 2012-11-22 Wisconsin Alumni Research Foundation N-cyclopropyl-(20r)-2-methylene-19,26,27-trinor-25-aza-vitamin d analogs and their uses
CN105492081A (zh) 2013-05-29 2016-04-13 博格有限责任公司 使用维生素d预防或减轻化疗诱发的脱发
US9338493B2 (en) 2014-06-30 2016-05-10 Apple Inc. Intelligent automated assistant for TV user interactions
US10548908B2 (en) 2016-09-15 2020-02-04 Nostopharma, LLC Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8929059D0 (en) * 1989-12-22 1990-02-28 Leo Pharm Prod Ltd Chemical compounds
CZ288031B6 (cs) * 1991-11-07 2001-04-11 Research Institute For Medicine And Chemistry Amidové deriváty vitaminu D, způsob výroby a farmaceutické prostředky s jejich obsahem

Also Published As

Publication number Publication date
DE69412476D1 (de) 1998-09-17
HU9503190D0 (en) 1996-01-29
IL109595A (en) 1999-04-11
CZ291238B6 (cs) 2003-01-15
HUT74165A (en) 1996-11-28
ES2122275T3 (es) 1998-12-16
FI955316A0 (fi) 1995-11-06
NO954426D0 (no) 1995-11-06
CN1125436A (zh) 1996-06-26
KR100321414B1 (ko) 2002-12-05
NZ265665A (en) 1997-05-26
WO1994026707A1 (en) 1994-11-24
CA2162272A1 (en) 1994-11-24
CZ290395A3 (en) 1996-06-12
US5756733A (en) 1998-05-26
ZA943162B (en) 1995-04-13
CN1093852C (zh) 2002-11-06
EP0696275A1 (en) 1996-02-14
JP3703099B2 (ja) 2005-10-05
DE69412476T2 (de) 1999-03-11
DK0696275T3 (da) 1998-11-09
IL109595A0 (en) 1994-08-26
NO309187B1 (no) 2000-12-27
AU6683294A (en) 1994-12-12
AU678246B2 (en) 1997-05-22
FI112361B (fi) 2003-11-28
ATE169617T1 (de) 1998-08-15
NO954426L (no) 1996-01-08
JPH08509971A (ja) 1996-10-22
EP0696275B1 (en) 1998-08-12
GB9309422D0 (en) 1993-06-23

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Legal Events

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MA Patent expired