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FI955261L - P-selectin antibodies and their use - Google Patents

P-selectin antibodies and their use Download PDF

Info

Publication number
FI955261L
FI955261L FI955261A FI955261A FI955261L FI 955261 L FI955261 L FI 955261L FI 955261 A FI955261 A FI 955261A FI 955261 A FI955261 A FI 955261A FI 955261 L FI955261 L FI 955261L
Authority
FI
Finland
Prior art keywords
selectin antibodies
selectin
antibodies
Prior art date
Application number
FI955261A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI955261A7 (en
FI955261A0 (en
Inventor
Robert W Chesnut
Margaret J Polley
James C Paulson
S Tarran Jones
Jose W Saldanha
Mary M Bendig
Michael Kriegler
Carl Perez
Robert Bayer
Michael Nunn
Original Assignee
Cytel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1993/004274 external-priority patent/WO1993021956A1/en
Priority claimed from US08/202,047 external-priority patent/US5800815A/en
Application filed by Cytel Corp filed Critical Cytel Corp
Publication of FI955261A0 publication Critical patent/FI955261A0/en
Publication of FI955261A7 publication Critical patent/FI955261A7/en
Publication of FI955261L publication Critical patent/FI955261L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056Lectin superfamily, e.g. CD23, CD72
    • C07K14/70564Selectins, e.g. CD62
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • C07K16/2854Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72 against selectins, e.g. CD62
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
FI955261A 1993-05-04 1994-05-04 P-selectin antibodies and their use FI955261L (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/US1993/004274 WO1993021956A1 (en) 1992-05-05 1993-05-04 Antibodies to p-selectin and their uses
US5729293A 1993-05-05 1993-05-05
US08/202,047 US5800815A (en) 1903-05-05 1994-02-25 Antibodies to P-selectin and their uses
PCT/US1994/004935 WO1994025067A1 (en) 1993-05-04 1994-05-04 Antibodies to p-selectin and their uses

Publications (3)

Publication Number Publication Date
FI955261A0 FI955261A0 (en) 1995-11-02
FI955261A7 FI955261A7 (en) 1996-01-03
FI955261L true FI955261L (en) 1996-01-03

Family

ID=27369213

Family Applications (1)

Application Number Title Priority Date Filing Date
FI955261A FI955261L (en) 1993-05-04 1994-05-04 P-selectin antibodies and their use

Country Status (3)

Country Link
EP (1) EP0804235A4 (en)
FI (1) FI955261L (en)
WO (1) WO1994025067A1 (en)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6155896A (en) * 1995-06-07 1996-12-30 Cytel Corporation Humanized antibodies to e-selectin
AU6390696A (en) * 1995-06-20 1997-01-22 Trustees Of Boston University Hypoxia-responsive adhesion molecules, specific antibodies, nd their uses
AU9603398A (en) * 1997-10-07 1999-04-27 Centocor Inc. Diagnosis of thrombotic events by detecting p-selectin
EP2374817B1 (en) * 2004-04-13 2017-09-06 F. Hoffmann-La Roche AG Anti-P-selectin antibodies
AU2012200852B2 (en) * 2004-04-13 2012-10-18 F. Hoffmann-La Roche Ag Anti-P-selectin antibodies
US20110212096A1 (en) 2006-12-01 2011-09-01 Scott Rollins Anti-p-selectin antibodies and methods of their use and identification
HUE041957T2 (en) 2006-12-01 2019-06-28 Novartis Ag Anti-P-selectin antibodies and methods of using the same to treat inflammatory diseases
US8945565B2 (en) 2006-12-01 2015-02-03 Selexys Pharmaceuticals Corporation Methods of treating inflammatory or thrombotic conditions with anti-P-selectin antibodies
PL2592148T3 (en) * 2007-10-12 2019-01-31 F. Hoffmann-La Roche Ag Protein expression from multiple nucleic acids
WO2019025847A1 (en) 2017-08-04 2019-02-07 Novartis Ag Treatment regimens
CN118161607A (en) 2018-03-08 2024-06-11 诺华股份有限公司 Uses of anti-P-selectin antibodies
WO2020247698A1 (en) 2019-06-07 2020-12-10 Novartis Ag Use of an anti-p-selectin antibody
EP4010019A1 (en) 2019-08-08 2022-06-15 Novartis AG Use of the anti-p-selectin antibody crizanlizumab for treating sickle cell nephropathy and chronic kidney disease associated with sickle cell disease
EP4213878A4 (en) * 2020-09-16 2024-07-03 Ramot at Tel-Aviv University Ltd. METHODS OF TREATMENT OF GLIOBLASTOMA

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL162181A (en) * 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
ES2097765T3 (en) * 1989-10-20 1997-04-16 New England Medical Center Inc A PADGEM INTERMEDIATED CELL LINKING INHIBITION SYSTEM.
DE69233254T2 (en) * 1991-06-14 2004-09-16 Genentech, Inc., South San Francisco Humanized Heregulin antibody
NZ286804A (en) * 1992-05-05 2000-08-25 Cytel Corp Treating inflammatory or thrombotic disease with a blocking P-selectin antibody

Also Published As

Publication number Publication date
WO1994025067A1 (en) 1994-11-10
FI955261A7 (en) 1996-01-03
EP0804235A4 (en) 2001-09-19
EP0804235A1 (en) 1997-11-05
FI955261A0 (en) 1995-11-02

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Legal Events

Date Code Title Description
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