FI955023L - Uudet trisykliset amidiyhdisteet, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset - Google Patents

Uudet trisykliset amidiyhdisteet, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset Download PDF

Info

Publication number: FI955023L
Authority: FI; Finland
Prior art keywords: preparation; methods; pharmaceutical compositions; compositions containing; amide compounds
Prior art date: 1994-10-21

Application number

FI955023A

Other languages

English (en)

Swedish (sv)

Other versions

FI955023A0 (fi

FI118565B (fi

Inventor

Daniel Lesieur

Patrick Depreux

Veronique Leclerc

Mansour Hamit Ait

Philippe Delagrange

Pierre Renard

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-21

Filing date

1995-10-20

Publication date

1996-04-22

1995-10-20 Application filed by Adir filed Critical Adir

1995-10-20 Publication of FI955023A0 publication Critical patent/FI955023A0/fi

1996-04-22 Publication of FI955023L publication Critical patent/FI955023L/fi

2007-12-31 Application granted granted Critical

2007-12-31 Publication of FI118565B publication Critical patent/FI118565B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/12—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups
- C07C233/13—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/17—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/20—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/60—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/92—Naphthopyrans; Hydrogenated naphthopyrans
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Diabetes (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Immunology (AREA)
Hematology (AREA)
Obesity (AREA)
Emergency Medicine (AREA)
Child & Adolescent Psychology (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Transplantation (AREA)
Endocrinology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Furan Compounds (AREA)
Pyrane Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Indole Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

FI955023A 1994-10-21 1995-10-20 Uudet trisykliset amidiyhdisteet, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset FI118565B (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9412581A FR2725985B1 (fr)	1994-10-21	1994-10-21	Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR9412581		1994-10-21

Publications (3)

Publication Number	Publication Date
FI955023A0 FI955023A0 (fi)	1995-10-20
FI955023L true FI955023L (fi)	1996-04-22
FI118565B FI118565B (fi)	2007-12-31

Family

ID=9468074

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI955023A FI118565B (fi)	1994-10-21	1995-10-20	Uudet trisykliset amidiyhdisteet, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset

Country Status (16)

Country	Link
US (1)	US5843986A (fi)
EP (1)	EP0708099B1 (fi)
JP (1)	JP2999143B2 (fi)
CN (2)	CN1053662C (fi)
AT (1)	ATE209641T1 (fi)
AU (1)	AU688586B2 (fi)
CA (1)	CA2160961C (fi)
DE (1)	DE69524186T2 (fi)
DK (1)	DK0708099T3 (fi)
ES (1)	ES2169113T3 (fi)
FI (1)	FI118565B (fi)
FR (1)	FR2725985B1 (fi)
NO (1)	NO314262B1 (fi)
NZ (1)	NZ280298A (fi)
PT (1)	PT708099E (fi)
ZA (1)	ZA958894B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6071946A (en) *	1994-10-21	2000-06-06	Adir Et Compagnie	Tricyclic urea compounds
US5998461A (en) *	1994-10-21	1999-12-07	Adir Et Compagnie	Tricyclic amide compounds
FR2739379B1 (fr) *	1995-09-29	1997-10-24	Adir	Nouveaux composes amines de 5,6,7,8-tetrahydronaphto(2,3-b) furane et d'indano(5,6-b)furane, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
US6034239A (en) *	1996-03-08	2000-03-07	Takeda Chemical Industries, Ltd.	Tricyclic compounds, their production and use
EP1199304A1 (en) *	1997-03-05	2002-04-24	Takeda Chemical Industries, Ltd.	Bicyclic compounds and pharmaceutical composition containing tricyclic compound for treating or preventing sleep disorders
EP0885210B2 (en) *	1996-03-08	2008-06-18	Takeda Pharmaceutical Company Limited	Tricylic compounds having binding affinity for melatonin receptors, their production and use
CA2274183C (en) *	1996-12-10	2006-10-24	Bristol-Myers Squibb Company	Benzodioxole, benzofuran, dihydrobenzofuran, and benzodioxane melatonergic agents
FR2763335B1 (fr) *	1997-05-16	2000-11-24	Adir	Nouveaux composes heterocycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2772766B1 (fr) *	1997-12-24	2000-06-30	Adir	Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2773798B1 (fr)	1998-01-16	2001-02-02	Adir	Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO1999062515A1 (en)	1998-06-05	1999-12-09	Bristol-Myers Squibb Company	Heterocyclic cis cyclopropane derivatives as melatonergic agents
WO2001002392A1 (en)	1999-06-30	2001-01-11	Bristol-Myers Squibb Company	Heterocyclic aminopyrrolidine derivatives as melatonergic agents
AU6595000A (en)	1999-08-20	2001-03-19	Takeda Chemical Industries Ltd.	Dihydrobenzofuran derivatives, process for the preparation thereof and agents
FR2805993B1 (fr) *	2000-03-08	2004-01-16	Adir	Utilisation de ligands melatoninergiques pour l'obtention de compositions pharmaceutiques destinees a la prevention ou au traitement du developpement de la tolerance aux composes nitres
US7012090B1 (en)	2000-03-17	2006-03-14	Alcon, Inc.	Pyranoindoles for treating glaucoma
AR061478A1 (es) *	2006-06-19	2008-08-27	Takeda Pharmaceutical	Compuesto triciclico y composicion farmaceutica
CN101605795A (zh)	2006-12-08	2009-12-16	武田药品工业株式会社	三环化合物及其药物用途
GB201002372D0 (en)	2010-02-12	2010-03-31	Element Six Production Pty Ltd	A superhard multiphase material and method of using same
CN107325011A (zh) *	2016-04-30	2017-11-07	陕西合成药业股份有限公司	一种褪黑激素类化合物及其制备方法和用途
IL309232A (en)	2021-06-14	2024-02-01	Scorpion Therapeutics Inc	Urea derivatives which can be used to treat cancer

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2613365B1 (fr) *	1987-04-01	1989-07-28	Adir	Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2613364B1 (fr) *	1987-04-01	1989-06-09	Adir	Nouvelles amines tricycliques derivees du tetrahydro-5, 6, 7, 8 naphto (2, 3b) dihydro-2, 3 furanne, et du tetrahydro-6, 7, 8, 9 5h-benzocyclohepta (2, 3b) dihydro-2, 3 furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2658818B1 (fr) *	1990-02-27	1993-12-31	Adir Cie	Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2680507B1 (fr) *	1991-08-23	1993-10-08	Adir Cie	Nouvelles naphtylethylurees et naphtylethylthiourees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2689124A1 (fr) *	1992-03-27	1993-10-01	Adir	Nouvelles naphtylalkylamines, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
GB9407919D0 (en) *	1994-04-21	1994-06-15	Glaxo Group Ltd	Chemical compounds

1994
- 1994-10-21 FR FR9412581A patent/FR2725985B1/fr not_active Expired - Fee Related
1995
- 1995-10-18 NO NO19954149A patent/NO314262B1/no not_active IP Right Cessation
- 1995-10-19 US US08/545,395 patent/US5843986A/en not_active Expired - Fee Related
- 1995-10-19 EP EP95402331A patent/EP0708099B1/fr not_active Expired - Lifetime
- 1995-10-19 ES ES95402331T patent/ES2169113T3/es not_active Expired - Lifetime
- 1995-10-19 CA CA002160961A patent/CA2160961C/fr not_active Expired - Fee Related
- 1995-10-19 AT AT95402331T patent/ATE209641T1/de not_active IP Right Cessation
- 1995-10-19 DK DK95402331T patent/DK0708099T3/da active
- 1995-10-19 DE DE69524186T patent/DE69524186T2/de not_active Expired - Fee Related
- 1995-10-19 PT PT95402331T patent/PT708099E/pt unknown
- 1995-10-20 CN CN95115980A patent/CN1053662C/zh not_active Expired - Fee Related
- 1995-10-20 ZA ZA958894A patent/ZA958894B/xx unknown
- 1995-10-20 JP JP7272750A patent/JP2999143B2/ja not_active Expired - Fee Related
- 1995-10-20 NZ NZ280298A patent/NZ280298A/en not_active IP Right Cessation
- 1995-10-20 AU AU34377/95A patent/AU688586B2/en not_active Ceased
- 1995-10-20 FI FI955023A patent/FI118565B/fi active IP Right Grant
1999
- 1999-12-15 CN CNB991261585A patent/CN1137889C/zh not_active Expired - Fee Related

Also Published As

Publication number	Publication date
CN1263095A (zh)	2000-08-16
CN1130184A (zh)	1996-09-04
PT708099E (pt)	2002-05-31
ZA958894B (en)	1996-05-14
NZ280298A (en)	1996-10-28
AU688586B2 (en)	1998-03-12
CA2160961C (fr)	2001-07-17
CN1053662C (zh)	2000-06-21
CN1137889C (zh)	2004-02-11
NO954149L (no)	1996-04-22
DK0708099T3 (da)	2002-02-11
FR2725985A1 (fr)	1996-04-26
AU3437795A (en)	1996-05-02
JPH08239377A (ja)	1996-09-17
FI955023A0 (fi)	1995-10-20
FI118565B (fi)	2007-12-31
JP2999143B2 (ja)	2000-01-17
US5843986A (en)	1998-12-01
EP0708099A1 (fr)	1996-04-24
CA2160961A1 (fr)	1996-04-22
EP0708099B1 (fr)	2001-11-28
FR2725985B1 (fr)	1996-11-15
HK1029116A1 (en)	2001-03-23
ES2169113T3 (es)	2002-07-01
NO314262B1 (no)	2003-02-24
NO954149D0 (no)	1995-10-18
DE69524186T2 (de)	2002-07-04
DE69524186D1 (de)	2002-01-10
ATE209641T1 (de)	2001-12-15

Publication	Publication Date	Title
EE9500064A (et)	1996-06-17	Asendatud 1H-imidasoolid, nende valmistamismeetodid ja farmatseutilised kompositsioonid
FI955024A7 (fi)	1996-04-22	Uudet piperidiiniyhdisteet, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
FI973148A7 (fi)	1997-09-29	Substituoituja heterosyklisiä yhdisteitä, menetelmä niiden valmistamis eksi ja niitä sisältäviä farmaseuttisia koostumuksia
FI955023L (fi)	1996-04-22	Uudet trisykliset amidiyhdisteet, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
EE03177B1 (et)	1999-04-15	Heterobitsüklilised ühendid, nende saamismeetod ja nimetatud ühendeid sisaldavad farmatseutilised kompositsioonid
FI953898L (fi)	1996-02-20	Glysiiniamidijohdannaisia, menetelmiä niiden valmistamiseksi ja niitä sisältäviä lääkeaineita
FI952550A7 (fi)	1995-11-28	Uudet N-pyridyylikarboksamidit ja johdannaiset, menetelmät niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
FI954304A7 (fi)	1996-03-16	Uudet bentsopyraanijohdannaiset, menetelmä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
FI943688L (fi)	1995-03-21	Uudet 11-bentsaldoksiimi-17beta-metoksi-27alfa-metoksi-metyyli-estradieenijohdannaiset, menetelmät niiden valmistamiseksi ja näitä sisältävät lääkeaineet
FI941836A7 (fi)	1994-10-23	3-deoksioligosakkaridit, menetelmiä niiden valmistamiseksi ja niitä sisältävät farmaseuttiset koostumukset
EE03825B1 (et)	2002-08-15	2-tsüanoiminoimidasooli derivaadid, nende valmistamismeetod, kasutamine ja farmatseutilised kompositsioonid
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