FI942167A0 - Optisesti aktiivinen 1-fenyylipyrrolidonijohdannainen, välituote sen valmistamiseksi ja menetelmä molempien valmistamiseksi - Google Patents
Optisesti aktiivinen 1-fenyylipyrrolidonijohdannainen, välituote sen valmistamiseksi ja menetelmä molempien valmistamiseksiInfo
- Publication number
- FI942167A0 FI942167A0 FI942167A FI942167A FI942167A0 FI 942167 A0 FI942167 A0 FI 942167A0 FI 942167 A FI942167 A FI 942167A FI 942167 A FI942167 A FI 942167A FI 942167 A0 FI942167 A0 FI 942167A0
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- optically active
- synthesis
- inhibit
- activity
- Prior art date
Links
- JMVIVASFFKKFQK-UHFFFAOYSA-N 1-phenylpyrrolidin-2-one Chemical class O=C1CCCN1C1=CC=CC=C1 JMVIVASFFKKFQK-UHFFFAOYSA-N 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 238000003786 synthesis reaction Methods 0.000 abstract 2
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000001308 synthesis method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24288792 | 1992-09-11 | ||
| JP24288792 | 1992-09-11 | ||
| JP9301274 | 1993-09-08 | ||
| PCT/JP1993/001274 WO1994006767A1 (fr) | 1992-09-11 | 1993-09-08 | Derive de 1-phenylpyrrolidone a activite optique, intermediaire permettant de le produire, et leurs procedes de production |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI942167A0 true FI942167A0 (fi) | 1994-05-10 |
| FI942167L FI942167L (fi) | 1994-07-08 |
| FI107605B FI107605B (fi) | 2001-09-14 |
Family
ID=17095708
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI942167A FI107605B (fi) | 1992-09-11 | 1994-05-10 | Optisesti aktiivinen 2-[1-(4-t-butyylifenyyli)-2-pyrrolidoni-4-yyli]metoksikarbonyylibentsoehapon alfa-fenyylietyyliamidi, välituote ja menetelmä sen valmistamiseksi |
| FI20001893A FI108130B (fi) | 1992-09-11 | 2000-08-28 | Menetelmä farmaseuttisesti aktiivisen (S)-(+)-4-[1-(4-t-butyylifenyyli)-2-pyrrolidon-4-yyli]metoksibentsoehapon tai sen esterin valmistamiseksi |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20001893A FI108130B (fi) | 1992-09-11 | 2000-08-28 | Menetelmä farmaseuttisesti aktiivisen (S)-(+)-4-[1-(4-t-butyylifenyyli)-2-pyrrolidon-4-yyli]metoksibentsoehapon tai sen esterin valmistamiseksi |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5475118A (fi) |
| EP (2) | EP0916657B9 (fi) |
| JP (1) | JP2724634B2 (fi) |
| KR (1) | KR0141657B1 (fi) |
| AT (2) | ATE186907T1 (fi) |
| AU (1) | AU663233B2 (fi) |
| CA (1) | CA2122705C (fi) |
| DE (2) | DE69333903T2 (fi) |
| DK (1) | DK0627419T3 (fi) |
| ES (2) | ES2139670T3 (fi) |
| FI (2) | FI107605B (fi) |
| HU (1) | HU215598B (fi) |
| NO (1) | NO300130B1 (fi) |
| WO (1) | WO1994006767A1 (fi) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2255245T3 (es) * | 1998-02-24 | 2006-06-16 | Taiho Pharmaceutical Company, Limited | Agentes de reduccion del porcentaje de lp (a) e inhibidores de la produccion de apoproteina (a). |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2657324B2 (ja) * | 1989-04-19 | 1997-09-24 | 大塚製薬株式会社 | ヘテロ環を有するフェニルカルボン酸誘導体 |
| JPH06192221A (ja) * | 1992-12-25 | 1994-07-12 | Taiho Yakuhin Kogyo Kk | 光学活性な１−（４−ｔ−ブチルフェニル）−５−オキソ−３−ピロリジンカルボン酸の製造方法 |
-
1993
- 1993-09-08 HU HU9401470A patent/HU215598B/hu not_active IP Right Cessation
- 1993-09-08 AT AT93919628T patent/ATE186907T1/de not_active IP Right Cessation
- 1993-09-08 KR KR1019940701558A patent/KR0141657B1/ko not_active Expired - Fee Related
- 1993-09-08 DE DE69333903T patent/DE69333903T2/de not_active Expired - Fee Related
- 1993-09-08 AU AU49832/93A patent/AU663233B2/en not_active Ceased
- 1993-09-08 ES ES93919628T patent/ES2139670T3/es not_active Expired - Lifetime
- 1993-09-08 CA CA002122705A patent/CA2122705C/en not_active Expired - Fee Related
- 1993-09-08 EP EP98203959A patent/EP0916657B9/en not_active Expired - Lifetime
- 1993-09-08 ES ES98203959T patent/ES2247657T3/es not_active Expired - Lifetime
- 1993-09-08 WO PCT/JP1993/001274 patent/WO1994006767A1/ja not_active Ceased
- 1993-09-08 US US08/211,950 patent/US5475118A/en not_active Expired - Fee Related
- 1993-09-08 JP JP6507962A patent/JP2724634B2/ja not_active Expired - Lifetime
- 1993-09-08 AT AT98203959T patent/ATE309212T1/de not_active IP Right Cessation
- 1993-09-08 EP EP93919628A patent/EP0627419B1/en not_active Expired - Lifetime
- 1993-09-08 DE DE69327092T patent/DE69327092T2/de not_active Expired - Fee Related
- 1993-09-08 DK DK93919628T patent/DK0627419T3/da active
-
1994
- 1994-05-10 FI FI942167A patent/FI107605B/fi active
- 1994-05-10 NO NO941757A patent/NO300130B1/no unknown
-
2000
- 2000-08-28 FI FI20001893A patent/FI108130B/fi active
Also Published As
| Publication number | Publication date |
|---|---|
| FI20001893L (fi) | 2000-08-28 |
| NO300130B1 (no) | 1997-04-14 |
| HU9401470D0 (en) | 1994-08-29 |
| DE69327092T2 (de) | 2000-05-25 |
| FI108130B (fi) | 2001-11-30 |
| CA2122705C (en) | 1997-11-18 |
| EP0627419A1 (en) | 1994-12-07 |
| EP0916657B9 (en) | 2006-05-17 |
| ES2139670T3 (es) | 2000-02-16 |
| EP0916657A1 (en) | 1999-05-19 |
| EP0627419B1 (en) | 1999-11-24 |
| FI942167L (fi) | 1994-07-08 |
| ATE309212T1 (de) | 2005-11-15 |
| NO941757D0 (no) | 1994-05-10 |
| AU663233B2 (en) | 1995-09-28 |
| DE69333903T2 (de) | 2006-07-27 |
| KR0141657B1 (ko) | 1998-06-01 |
| AU4983293A (en) | 1994-04-12 |
| JP2724634B2 (ja) | 1998-03-09 |
| ES2247657T3 (es) | 2006-03-01 |
| DE69333903D1 (de) | 2005-12-15 |
| HUT70219A (en) | 1995-09-28 |
| FI107605B (fi) | 2001-09-14 |
| HU215598B (hu) | 1999-01-28 |
| NO941757L (no) | 1994-05-10 |
| US5475118A (en) | 1995-12-12 |
| WO1994006767A1 (fr) | 1994-03-31 |
| ATE186907T1 (de) | 1999-12-15 |
| EP0916657B1 (en) | 2005-11-09 |
| DK0627419T3 (da) | 2000-04-25 |
| EP0627419A4 (en) | 1995-02-08 |
| CA2122705A1 (en) | 1994-03-31 |
| DE69327092D1 (de) | 1999-12-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| HU913396D0 (en) | Process for the production of azasteroide compounds and medical preparations containing them as active agents | |
| NO944370L (no) | Gamma-aminosyre- og L-glutaminsyreanaloger for behandling av anfall | |
| HUT65593A (en) | Process for producing ester derivatives of hexahidro naphthaline and pharmaceutical compositions containing them | |
| AU3381389A (en) | Derivative of caffeic acid and pharmaceutical composition containing the same | |
| DE3884555D1 (de) | Octahydronaphthalenoxim-derivate fuer cholesterolsynthese-inhibierung, verfahren fuer deren herstellung und diese enthaltende zusammenstellungen. | |
| FI913067A0 (fi) | Bisfosfonsyraderivat, deras framstaellning och anvaendning. | |
| HUT50337A (en) | Process for producing benzoxazine derivatives and pharmaceutical compositions comprising the compounds | |
| NO940265D0 (no) | Fremgangsmaate ved fremstilling av svovelholdige karboksylsyreamider | |
| FI942167A0 (fi) | Optisesti aktiivinen 1-fenyylipyrrolidonijohdannainen, välituote sen valmistamiseksi ja menetelmä molempien valmistamiseksi | |
| AU4953997A (en) | New histidine derivatives, preparation process, and their use as free antiradical agents | |
| PT99043A (pt) | Processo para a preparacao de composicoes biocidas contendo derivados de 4,5-polimetileno-4-isotiazolin-3-onas | |
| BR8603787A (pt) | Compostos heterociclicos,e,processo de sua preparacao e aplicacao | |
| ES2144327T3 (es) | Procedimiento para preparar un compuesto de 2-cianobifenilo. | |
| HU910108D0 (en) | Process for the production of macrolide compounds | |
| HUT54688A (en) | Process for producing compounds utilizable for treating ulcus and pharmaceutical compositions containing them as active components | |
| MX9804264A (es) | Proceso para la preparacion de derivados de acido metoximino-fenilglioxilico. | |
| ATE86629T1 (de) | 4-piperidincarboxamid-derivate. | |
| ES8404989A1 (es) | Un procedimiento para preparar 4-(2-hidroxietil)-2-azetidinona opticamente activa. |