FI940889A7 - Nya isazinoximderivat, deras preparation och användning - Google Patents

Nya isazinoximderivat, deras preparation och användning

Info

Publication number: FI940889A7
Authority: FI; Finland
Prior art keywords: isazine; preparation; new; oxime derivatives; oxime
Prior art date: 1991-08-28

Application number

FI940889A

Other languages

English (en)

Finnish (fi)

Other versions

FI107156B (sv

FI940889A0 (sv

Inventor

Frank Watjen

Bjarne Hugo Dahl

Jorgen Drejer

Leif Helth Jensen

Original Assignee

Neurosearch As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-08-28

Filing date

1994-02-25

Publication date

1994-02-25

1994-02-25 Application filed by Neurosearch As filed Critical Neurosearch As

1994-02-25 Publication of FI940889A7 publication Critical patent/FI940889A7/sv

1994-02-25 Publication of FI940889A0 publication Critical patent/FI940889A0/sv

2001-06-15 Application granted granted Critical

2001-06-15 Publication of FI107156B publication Critical patent/FI107156B/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

FI940889A 1991-08-28 1994-02-25 Förfarande för framställning av farmakologiskt aktiva indol-2,3-dion-3-oximderivat FI107156B (sv)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US75116591A	1991-08-28	1991-08-28
US75116591		1991-08-28
US83185192A	1992-02-05	1992-02-05
US83185192		1992-02-05
EP9201999		1992-08-27
PCT/EP1992/001999 WO1993005043A1 (en)	1991-08-28	1992-08-27	Novel isatinoxime derivatives, their preparation and use

Publications (3)

Publication Number	Publication Date
FI940889A7 true FI940889A7 (sv)	1994-02-25
FI940889A0 FI940889A0 (sv)	1994-02-25
FI107156B FI107156B (sv)	2001-06-15

Family

ID=27115380

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI940889A FI107156B (sv)	1991-08-28	1994-02-25	Förfarande för framställning av farmakologiskt aktiva indol-2,3-dion-3-oximderivat

Country Status (18)

Country	Link
EP (1)	EP0529636B1 (sv)
JP (1)	JP3170584B2 (sv)
KR (1)	KR100277481B1 (sv)
AT (1)	ATE181552T1 (sv)
AU (1)	AU655672B2 (sv)
CA (1)	CA2076948C (sv)
CZ (1)	CZ282759B6 (sv)
DE (1)	DE69229461T2 (sv)
DK (1)	DK0529636T3 (sv)
FI (1)	FI107156B (sv)
GE (1)	GEP20002329B (sv)
HU (2)	HUT70753A (sv)
MX (1)	MX9204914A (sv)
NO (1)	NO301117B1 (sv)
PL (1)	PL170920B1 (sv)
RU (1)	RU2114827C1 (sv)
SK (1)	SK280578B6 (sv)
WO (1)	WO1993005043A1 (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH08502483A (ja)	1992-10-13	1996-03-19	ワーナー−ランバート・コンパニー	新規なキノキサリンジオン誘導体、それらの製造および使用
US5843945A (en) *	1993-05-13	1998-12-01	Neurosearch A/S	AMPA antagonists and a method of treatment
FI954965L (sv) *	1993-05-13	1995-11-10	Neurosearch As	AMPA-antagonister och behandlingsmetod där dessa används
DK81593D0 (da) *	1993-07-07	1993-07-07	Neurosearch As	Nye isatinoximderivater, deres fremstilling og anvendelse
DE69514533T2 (de) *	1994-09-14	2000-07-06	Neurosearch A/S, Ballerup	Kondensierte indole und chinoxalinderivate, ihre herstellung und verwendung als glutamatantagonisten
WO1996008494A1 (en) *	1994-09-14	1996-03-21	Neurosearch A/S	Indole-2,3-dione-3-oxime derivatives, their preparation and use
UA54403C2 (uk) *	1996-10-01	2003-03-17	Н'Юросерч А/С	Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму
FR2768624B1 (fr) *	1997-09-25	1999-11-12	Oreal	Utilisation d'un inhibiteur d'acides amines excitateurs dans une composition cosmetique ou dermatologique pour peaux sensibles et composition obtenue
DK1183025T3 (da)	1999-05-19	2009-05-04	Painceptor Pharma Corp	Hæmmere af proton-styrede kationskanaler og deres anvendelse til behandling af iskæmiske lidelser
AU781067B2 (en)	2000-01-24	2005-05-05	Neurosearch A/S	Isatine derivatives with neurotrophic activity
AU2003273114A1 (en)	2002-10-29	2004-05-25	Sungkyunkwan University	Medicament component of berberine for the use of prevention and treatment of psycological dependence on and analgesic tolerance to morphine
BRPI0618863A2 (pt)	2005-11-23	2016-09-13	Painceptor Pharma Corp	métodos de modular a atividade de um canal iônico dependente e de tratar dor, uma transtorno associado aos sistemas genitourinário ou gastrointestinal em um indivíduo e, composto
EA027009B1 (ru) *	2012-12-19	2017-06-30	Байер Кропсайенс Акциенгезельшафт	Дифторметилникотиновые инданилкарбоксамиды
US9815768B2 (en) *	2014-02-28	2017-11-14	Sumitomo Chemical Company, Limited	Method for producing 2-(halogenomethyl)-3-methylnitrobenzene
CA3017751A1 (en) *	2016-03-17	2017-09-21	Fmc Corporation	Process for converting s-enantiomer to its racemic form
CN112266368B (zh) *	2017-11-15	2024-03-19	中山光禾医疗科技有限公司	光交联水凝胶材料的制备、原料、产品及应用
CN108912127B (zh) *	2018-08-27	2019-12-10	青岛农业大学	一种基于靛红骨架的苯并[b,e]氮杂卓化合物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE69677B1 (en) *	1989-12-11	1996-10-02	Neurosearch As	Isatine derivatives their preparation and use

1992
- 1992-08-26 CA CA002076948A patent/CA2076948C/en not_active Expired - Fee Related
- 1992-08-26 MX MX9204914A patent/MX9204914A/es not_active IP Right Cessation
- 1992-08-27 HU HU9400595A patent/HUT70753A/hu unknown
- 1992-08-27 JP JP50493393A patent/JP3170584B2/ja not_active Expired - Fee Related
- 1992-08-27 EP EP92114654A patent/EP0529636B1/en not_active Expired - Lifetime
- 1992-08-27 CZ CZ94395A patent/CZ282759B6/cs not_active IP Right Cessation
- 1992-08-27 WO PCT/EP1992/001999 patent/WO1993005043A1/en not_active Ceased
- 1992-08-27 SK SK238-94A patent/SK280578B6/sk unknown
- 1992-08-27 RU RU94019425/04A patent/RU2114827C1/ru not_active IP Right Cessation
- 1992-08-27 AT AT92114654T patent/ATE181552T1/de not_active IP Right Cessation
- 1992-08-27 PL PL92302584A patent/PL170920B1/pl unknown
- 1992-08-27 GE GEAP19922683A patent/GEP20002329B/en unknown
- 1992-08-27 DK DK92114654T patent/DK0529636T3/da active
- 1992-08-27 DE DE69229461T patent/DE69229461T2/de not_active Expired - Lifetime
- 1992-08-27 KR KR1019940700676A patent/KR100277481B1/ko not_active Expired - Fee Related
- 1992-08-27 AU AU24820/92A patent/AU655672B2/en not_active Ceased
1994
- 1994-02-25 NO NO940676A patent/NO301117B1/no unknown
- 1994-02-25 FI FI940889A patent/FI107156B/sv active
1995
- 1995-06-21 HU HU95P/P00323P patent/HU211632A9/hu unknown

Also Published As

Publication number	Publication date
CZ282759B6 (cs)	1997-09-17
HUT70753A (en)	1995-10-30
NO301117B1 (no)	1997-09-15
KR100277481B1 (ko)	2001-02-01
CA2076948A1 (en)	1993-03-01
DE69229461T2 (de)	1999-10-21
ATE181552T1 (de)	1999-07-15
FI107156B (sv)	2001-06-15
GEP20002329B (en)	2000-12-25
HU211632A9 (en)	1995-12-28
NO940676D0 (no)	1994-02-25
RU2114827C1 (ru)	1998-07-10
SK280578B6 (sk)	2000-04-10
WO1993005043A1 (en)	1993-03-18
CZ39594A3 (en)	1994-11-16
CA2076948C (en)	2002-04-16
AU2482092A (en)	1993-04-05
JP3170584B2 (ja)	2001-05-28
HU9400595D0 (en)	1994-05-30
DK0529636T3 (da)	1999-12-13
PL170920B1 (pl)	1997-02-28
AU655672B2 (en)	1995-01-05
MX9204914A (es)	1993-07-01
DE69229461D1 (de)	1999-07-29
EP0529636A1 (en)	1993-03-03
SK23894A3 (en)	1994-12-07
JPH06510056A (ja)	1994-11-10
NO940676L (sv)	1994-04-27
FI940889A0 (sv)	1994-02-25
EP0529636B1 (en)	1999-06-23

Publication	Publication Date	Title
FI955248A7 (sv)	1995-11-02	1-Bifenylmetylimidazolderivat, framställning och terapeutisk användning av dessa
FI934426A7 (sv)	1993-10-08	Tiazolidindionderivat, framställning och användning därav
FI935074A7 (sv)	1993-11-16	Nya tiopyranopyrrolderivat och framställning av dem
FI952179A7 (sv)	1995-05-05	Nya 3,3-difenylpropylaminer, användning och framställning därav
FI955235L (sv)	1996-05-03	Oxazolidindionderivat, deras framställning och användning
FI935072A7 (sv)	1993-11-16	Nya perhydroisoindoler och deras framställning
FI935897L (sv)	1994-06-30	Pyridopyrimidinderivat deras framstaellning och anvaendning
FI935887L (sv)	1994-06-29	Tiazolidindionderivat, deras framstaellning och anvaendning
FI921459A7 (sv)	1992-10-04	Piperidinderivat, framställning av dessa samt terapeutisk användning av dessa
FI940696A7 (sv)	1994-02-15	Nya pyrazinderivat, deras framställning och användning
FI915099A7 (sv)	1992-08-11	Tienoimidazolderivat, deras framställning och användning
FI940889A7 (sv)	1994-02-25	Nya isazinoximderivat, deras preparation och användning
FI914611A7 (sv)	1992-04-03	2-aminopyrimidin-4-karboxamidderivat, framställning och terapeutisk användning av dem
FI931011A7 (sv)	1993-09-10	Kondenserade heterocykliska ketonderivat, deras framställning och användning
FI941287L (sv)	1994-03-18	Triazolokinoxalin-1,4-dioner och framställning och användning av dem
FI922982A7 (sv)	1992-12-28	2-aminopyrimidin-4-karboxamidderivat, framställning av dessa och terapeutisk användning av dessa
FI934680A7 (sv)	1993-10-22	Arylmorfolin, framställning och använding
FI930716A7 (sv)	1993-08-21	Nya arylkarbonylaminoalkyldihydrooxopyridiner, framställning och användning av dessa
FI955679A0 (sv)	1995-11-24	Piperidinderivater, framställning och användning därav
FI944040A7 (sv)	1995-03-04	Laktolderivat, deras framställning och användning
FI923458A7 (sv)	1992-07-31	4,5-cykloalkano-3-benzazepin-7-olderivat och deras användning
FI921814A7 (sv)	1992-10-25	2-aminopyrimidin-4-karboxiamidderivat, deras framställning och terapeutisk användning av dem
FI920663A7 (sv)	1992-08-16	Polyhydroxicyklopentanderivat, deras framställning och terapeutiska användning
FI941963L (sv)	1994-10-29	Pyridinderivat, deras framställning och användning
FI924053A7 (sv)	1993-03-15	Substituerade aminopropaner, förfarande för deras framställning och deras användning