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FI940519L - Användning av interleukin-10-analoger eller -antagonister för skötsel av endotoxin eller superantingen inducerad toxicitet - Google Patents

Användning av interleukin-10-analoger eller -antagonister för skötsel av endotoxin eller superantingen inducerad toxicitet Download PDF

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Publication number
FI940519L
FI940519L FI940519A FI940519A FI940519L FI 940519 L FI940519 L FI 940519L FI 940519 A FI940519 A FI 940519A FI 940519 A FI940519 A FI 940519A FI 940519 L FI940519 L FI 940519L
Authority
FI
Finland
Prior art keywords
superantigen
endotoxin
interleukin
analogues
antagonists
Prior art date
Application number
FI940519A
Other languages
English (en)
Finnish (fi)
Other versions
FI940519A0 (sv
FI940519A7 (sv
Inventor
Waal Malefyt Rene De
Maureen Howard
Di-Hwei Hsu
Hiroshi Ishida
Anne O'garra
Hergen Spits
Albert Zlotnik
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of FI940519L publication Critical patent/FI940519L/sv
Publication of FI940519A0 publication Critical patent/FI940519A0/sv
Publication of FI940519A7 publication Critical patent/FI940519A7/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5428—IL-10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Vascular Medicine (AREA)
  • Oncology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Virology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
FI940519A 1991-08-06 1992-08-06 Användning av interleukin-10-analoger eller -antagonister för skötsel av endotoxin eller superantingen inducerad toxicitet FI940519A7 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US74212991A 1991-08-06 1991-08-06
PCT/US1992/006378 WO1993002693A2 (en) 1991-08-06 1992-08-06 Use of interleukin-10 analogs or antagonists to treat endotoxin- or superantigen induced toxicity

Publications (3)

Publication Number Publication Date
FI940519L true FI940519L (sv) 1994-02-04
FI940519A0 FI940519A0 (sv) 1994-02-04
FI940519A7 FI940519A7 (sv) 1994-02-04

Family

ID=24983602

Family Applications (1)

Application Number Title Priority Date Filing Date
FI940519A FI940519A7 (sv) 1991-08-06 1992-08-06 Användning av interleukin-10-analoger eller -antagonister för skötsel av endotoxin eller superantingen inducerad toxicitet

Country Status (17)

Country Link
EP (2) EP0541214A3 (sv)
JP (3) JPH07502019A (sv)
KR (1) KR100271197B1 (sv)
AT (1) ATE187336T1 (sv)
AU (1) AU678137B2 (sv)
CA (1) CA2115060C (sv)
CZ (1) CZ281796B6 (sv)
DE (1) DE69230403T2 (sv)
DK (1) DK0600970T3 (sv)
ES (1) ES2138976T3 (sv)
FI (1) FI940519A7 (sv)
GR (1) GR3032167T3 (sv)
HU (1) HU224437B1 (sv)
NO (1) NO315409B1 (sv)
PT (1) PT600970E (sv)
SK (1) SK282947B6 (sv)
WO (1) WO1993002693A2 (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3801193A (en) * 1992-03-20 1993-10-21 Schering Corporation Use of interleukin-10 to induce the production of interleukin-1 receptor antagonist
JPH08501549A (ja) * 1992-09-18 1996-02-20 スケアリング コーポレイション Ｈｉｖ感染された患者におけるｔヘルパー細胞の免疫担当能力の回復
EP0681589A1 (en) * 1993-02-01 1995-11-15 Université Libre de Bruxelles Use of a pharmaceutical composition comprising an effective amount of interleukin-10, an analog and/or an agonist of interleukin-10
CA2168110A1 (en) * 1993-07-26 1995-02-02 Chuan-Chu Chou Agonists and antagonists of human interleukin-10
EP1013764A1 (en) 1994-07-05 2000-06-28 Steeno Research Group A/S Immunomodulators
US5753218A (en) * 1996-05-03 1998-05-19 Schering Corporation Method for treating inflammation
JPWO2002066069A1 (ja) * 2001-02-20 2004-09-24 関西ティー・エル・オー株式会社 炎症・腫瘍性疾患治療剤
PE20090047A1 (es) * 2003-11-10 2009-01-26 Schering Corp Anticuerpo recombinante humanizado anti-interleuquina 10
CN102811736B (zh) 2009-11-30 2016-01-20 生物测试股份公司 治疗系统性红斑狼疮(sle)的人源化抗il-10抗体
CA2899835A1 (en) 2013-03-20 2014-09-25 F. Hoffmann-La Roche Ag Specific detection of rat antibodies in mouse serum

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL94878A (en) * 1989-06-28 2003-01-12 Schering Corp Cytokine synthesis inhibitory factor, antagonists thereof and methods of using same
CZ283049B6 (cs) * 1989-12-20 1997-12-17 Schering Corporation Protein BCRF1 viru Epstein-Barr schopný inhibovat syntézu gama-interferonu, expresní vekter pro jeho syntézu a farmaceutický přípravek jej obsahující

Also Published As

Publication number Publication date
GR3032167T3 (en) 2000-04-27
ATE187336T1 (de) 1999-12-15
DE69230403D1 (de) 2000-01-13
WO1993002693A3 (en) 1993-07-22
CZ281796B6 (cs) 1997-02-12
PT600970E (pt) 2000-05-31
EP0600970B1 (en) 1999-12-08
NO940370L (no) 1994-02-04
JPH07502019A (ja) 1995-03-02
SK282947B6 (sk) 2003-01-09
EP0600970A1 (en) 1994-06-15
CA2115060A1 (en) 1993-02-18
AU2441192A (en) 1993-03-02
AU678137B2 (en) 1997-05-22
HU9400314D0 (en) 1994-05-30
SK12994A3 (en) 1994-12-07
EP0541214A3 (en) 1993-09-08
FI940519A0 (sv) 1994-02-04
JP2008013573A (ja) 2008-01-24
JP2004250454A (ja) 2004-09-09
ES2138976T3 (es) 2000-02-01
NO315409B1 (no) 2003-09-01
CA2115060C (en) 2003-05-06
CZ24394A3 (en) 1995-01-18
DE69230403T2 (de) 2000-05-11
NO940370D0 (no) 1994-02-04
EP0541214A2 (en) 1993-05-12
FI940519A7 (sv) 1994-02-04
DK0600970T3 (da) 2000-05-29
HU224437B1 (hu) 2005-09-28
WO1993002693A2 (en) 1993-02-18
KR100271197B1 (ko) 2000-11-01
HUT66865A (en) 1995-01-30

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