FI946085L - Uusia nikotiinihappoestereitä - Google Patents
Uusia nikotiinihappoestereitä Download PDFInfo
- Publication number
- FI946085L FI946085L FI946085A FI946085A FI946085L FI 946085 L FI946085 L FI 946085L FI 946085 A FI946085 A FI 946085A FI 946085 A FI946085 A FI 946085A FI 946085 L FI946085 L FI 946085L
- Authority
- FI
- Finland
- Prior art keywords
- acid esters
- nicotinic acid
- new nicotinic
- new
- esters
- Prior art date
Links
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical class OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9201956A SE9201956D0 (sv) | 1992-06-25 | 1992-06-25 | Novel nicotinicacid esters |
| SE9201956 | 1992-06-25 | ||
| SE9300565 | 1993-02-22 | ||
| PCT/SE1993/000565 WO1994000434A1 (en) | 1992-06-25 | 1993-06-23 | Novel nicotinic acid esters |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI946085A0 FI946085A0 (fi) | 1994-12-23 |
| FI946085L true FI946085L (fi) | 1994-12-23 |
| FI107151B FI107151B (fi) | 2001-06-15 |
Family
ID=20386602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI946085A FI107151B (fi) | 1992-06-25 | 1994-12-23 | Menetelmä uusien terapeuttisesti käyttökelpoisten 2-[4-(4,4-bis(4-fluorifenyyli)butyyli)piperatsin-1-yyli]pyridin-3-yyli-karboksyyliestrereiden valmistamiseksi |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5658910A (fi) |
| EP (2) | EP0673368B1 (fi) |
| JP (1) | JP3306827B2 (fi) |
| KR (1) | KR100302216B1 (fi) |
| CN (1) | CN1085981C (fi) |
| AT (2) | ATE209634T1 (fi) |
| AU (1) | AU681346B2 (fi) |
| BG (1) | BG62000B1 (fi) |
| CA (1) | CA2139112C (fi) |
| CZ (1) | CZ281975B6 (fi) |
| DE (2) | DE69331234T2 (fi) |
| DK (1) | DK0673368T3 (fi) |
| EE (1) | EE03122B1 (fi) |
| ES (1) | ES2169044T3 (fi) |
| FI (1) | FI107151B (fi) |
| HU (2) | HU220613B1 (fi) |
| IL (1) | IL106135A (fi) |
| NO (1) | NO302945B1 (fi) |
| NZ (1) | NZ253823A (fi) |
| PH (1) | PH31417A (fi) |
| PT (1) | PT673368E (fi) |
| RO (1) | RO115725B1 (fi) |
| RU (1) | RU2127732C1 (fi) |
| SE (1) | SE9201956D0 (fi) |
| SK (1) | SK279393B6 (fi) |
| WO (1) | WO1994000434A1 (fi) |
| ZA (1) | ZA934596B (fi) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6632823B1 (en) * | 1997-12-22 | 2003-10-14 | Merck & Co., Inc. | Substituted pyridine compounds useful as modulators of acetylcholine receptors |
| KR100581199B1 (ko) | 1998-06-19 | 2006-05-17 | 카이론 코포레이션 | 글리코겐 신타제 키나제 3의 억제제 |
| US7045519B2 (en) * | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| WO2000066558A1 (en) * | 1999-05-04 | 2000-11-09 | Schering Corporation | Piperazine derivatives useful as ccr5 antagonists |
| SE9904673D0 (sv) * | 1999-12-20 | 1999-12-20 | Astra Pharma Inc | Novel compounds |
| AR035974A1 (es) * | 2001-05-18 | 2004-07-28 | Astrazeneca Ab | Derivados de diarilmetil piperazina, procesos para su preparacion, uso de estos derivados para la elaboracion de medicamentos y composicion farmaceutica |
| GB0224917D0 (en) * | 2002-10-25 | 2002-12-04 | Novartis Ag | Organic compounds |
| FR2902426B1 (fr) * | 2006-06-19 | 2008-09-05 | Pierre Fabre Medicament Sa | Derives de cinnamoyl-piperazine |
| CN112105604B (zh) | 2018-05-09 | 2024-01-09 | 株式会社Lg化学 | 表现出肠肽酶抑制活性的新型化合物 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4457931A (en) * | 1982-09-27 | 1984-07-03 | Selvi & C. S.P.A. | Piperazine derivatives with anticholinergic and/or antihistaminic activity |
| EP0264883A3 (en) * | 1986-10-21 | 1990-04-04 | Banyu Pharmaceutical Co., Ltd. | Substituted pyridine derivatives |
| SE8701375D0 (sv) * | 1987-04-02 | 1987-04-02 | Leo Ab | Novel pyridyl- and pyrimidyl derivatives |
| SE8803429D0 (sv) * | 1988-09-28 | 1988-09-28 | Pharmacia Ab | Novel pyridyl- and pyrimidyl derivatives |
| JP2664238B2 (ja) * | 1989-03-01 | 1997-10-15 | 日清製粉株式会社 | ニコチン酸またはそのエステル誘導体 |
| US4956368A (en) * | 1989-07-24 | 1990-09-11 | Bristol-Myers Company | Metabolites and prodrug formulations of 8-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione |
| EP0441226A1 (en) * | 1990-01-29 | 1991-08-14 | J. URIACH & CIA. S.A. | (cyanomethyl)pyridines useful as PAF antagonists |
| IE911774A1 (en) * | 1990-06-11 | 1991-12-18 | Akzo Nv | Pyridinylpiperazine derivatives |
| SE9201239D0 (sv) * | 1992-04-21 | 1992-04-21 | Kabi Pharmacia Ab | Agents for treating substance abuse disorders |
| SE9202265D0 (sv) * | 1992-07-31 | 1992-07-31 | Kabi Pharmacia Ab | Novel- pyridyl and pyrimidylpiperazine derivatives |
-
1992
- 1992-06-25 SE SE9201956A patent/SE9201956D0/xx unknown
-
1993
- 1993-06-23 CZ CZ943274A patent/CZ281975B6/cs not_active IP Right Cessation
- 1993-06-23 JP JP50226894A patent/JP3306827B2/ja not_active Expired - Fee Related
- 1993-06-23 CA CA002139112A patent/CA2139112C/en not_active Expired - Fee Related
- 1993-06-23 DK DK93915075T patent/DK0673368T3/da active
- 1993-06-23 AU AU45193/93A patent/AU681346B2/en not_active Ceased
- 1993-06-23 RU RU94046310A patent/RU2127732C1/ru not_active IP Right Cessation
- 1993-06-23 KR KR1019940704643A patent/KR100302216B1/ko not_active Expired - Fee Related
- 1993-06-23 PT PT93915075T patent/PT673368E/pt unknown
- 1993-06-23 WO PCT/SE1993/000565 patent/WO1994000434A1/en not_active Ceased
- 1993-06-23 SK SK1585-94A patent/SK279393B6/sk not_active IP Right Cessation
- 1993-06-23 AT AT93915075T patent/ATE209634T1/de not_active IP Right Cessation
- 1993-06-23 EP EP93915075A patent/EP0673368B1/en not_active Expired - Lifetime
- 1993-06-23 RO RO94-02087A patent/RO115725B1/ro unknown
- 1993-06-23 HU HU9403786A patent/HU220613B1/hu not_active IP Right Cessation
- 1993-06-23 EP EP01108668A patent/EP1120410B1/en not_active Expired - Lifetime
- 1993-06-23 DE DE69331234T patent/DE69331234T2/de not_active Expired - Fee Related
- 1993-06-23 NZ NZ253823A patent/NZ253823A/en not_active IP Right Cessation
- 1993-06-23 DE DE69333655T patent/DE69333655D1/de not_active Expired - Lifetime
- 1993-06-23 ES ES93915075T patent/ES2169044T3/es not_active Expired - Lifetime
- 1993-06-23 AT AT01108668T patent/ATE278671T1/de not_active IP Right Cessation
- 1993-06-23 US US08/362,475 patent/US5658910A/en not_active Expired - Lifetime
- 1993-06-24 IL IL10613593A patent/IL106135A/en not_active IP Right Cessation
- 1993-06-25 CN CN93116250A patent/CN1085981C/zh not_active Expired - Fee Related
- 1993-06-25 ZA ZA934596A patent/ZA934596B/xx unknown
-
1994
- 1994-11-17 EE EE9400400A patent/EE03122B1/xx not_active IP Right Cessation
- 1994-12-22 BG BG99289A patent/BG62000B1/bg unknown
- 1994-12-23 NO NO945022A patent/NO302945B1/no not_active IP Right Cessation
- 1994-12-23 FI FI946085A patent/FI107151B/fi active
-
1995
- 1995-05-23 HU HU95P/P00139P patent/HU210875A9/hu unknown
-
1998
- 1998-06-24 PH PH4640898A patent/PH31417A/en unknown
Also Published As
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