FI945811A7 - Des-Tyr-dynorphin analogs - Google Patents
Des-Tyr-dynorphin analogs Download PDFInfo
- Publication number
- FI945811A7 FI945811A7 FI945811A FI945811A FI945811A7 FI 945811 A7 FI945811 A7 FI 945811A7 FI 945811 A FI945811 A FI 945811A FI 945811 A FI945811 A FI 945811A FI 945811 A7 FI945811 A7 FI 945811A7
- Authority
- FI
- Finland
- Prior art keywords
- tyr
- des
- dynorphin analogs
- dynorphin
- analogs
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Addiction (AREA)
- Toxicology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89792092A | 1992-06-12 | 1992-06-12 | |
| PCT/US1993/005161 WO1993025217A1 (en) | 1992-06-12 | 1993-06-01 | Des-tyr dynorphin analogues |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI945811A0 FI945811A0 (en) | 1994-12-09 |
| FI945811A7 true FI945811A7 (en) | 1995-02-06 |
| FI945811L FI945811L (en) | 1995-02-06 |
Family
ID=25408662
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI945811A FI945811L (en) | 1992-06-12 | 1993-06-01 | Des-Tyr dynorphin analogs |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0652765A4 (en) |
| JP (1) | JPH08501075A (en) |
| KR (1) | KR950701818A (en) |
| AU (1) | AU4399093A (en) |
| CA (1) | CA2137916A1 (en) |
| CZ (1) | CZ281630B6 (en) |
| FI (1) | FI945811L (en) |
| HU (1) | HUT70160A (en) |
| NO (1) | NO944778L (en) |
| RU (1) | RU95106651A (en) |
| WO (1) | WO1993025217A1 (en) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5482930A (en) * | 1993-06-09 | 1996-01-09 | The Regents Of The University Of California | Anti-inflammatory composition and method with des-Tyr dynorphin and analogues |
| IL134796A0 (en) | 1997-09-04 | 2001-04-30 | Novoneuron Inc | Noribogaine in the treatment of pain and drug addiction |
| US7220737B1 (en) | 1997-09-04 | 2007-05-22 | Novoneuron, Inc | Noribogaine in the treatment of pain and drug addiction |
| US6437092B1 (en) | 1998-11-06 | 2002-08-20 | Conjuchem, Inc. | Conjugates of opioids and endogenous carriers |
| EP1598365A1 (en) | 1999-05-17 | 2005-11-23 | ConjuChem Inc. | Protection of endogenous therapeutic peptides |
| US7601691B2 (en) | 1999-05-17 | 2009-10-13 | Conjuchem Biotechnologies Inc. | Anti-obesity agents |
| US6887470B1 (en) | 1999-09-10 | 2005-05-03 | Conjuchem, Inc. | Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components |
| US6849714B1 (en) | 1999-05-17 | 2005-02-01 | Conjuchem, Inc. | Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components |
| US6706892B1 (en) | 1999-09-07 | 2004-03-16 | Conjuchem, Inc. | Pulmonary delivery for bioconjugation |
| WO2002062844A2 (en) | 2001-02-02 | 2002-08-15 | Conjuchem Inc. | Long lasting growth hormone releasing factor derivatives |
| EP1360202B1 (en) | 2001-02-16 | 2008-05-21 | ConjuChem Biotechnologies Inc. | Long lasting glucagon-like peptide 2 (glp-2) for the treatment of gastrointestinal diseases and disorders |
| US8765737B1 (en) | 2010-05-11 | 2014-07-01 | Demerx, Inc. | Methods and compositions for preparing and purifying noribogaine |
| US9394294B2 (en) | 2010-05-11 | 2016-07-19 | Demerx, Inc. | Methods and compositions for preparing and purifying noribogaine |
| US8362007B1 (en) | 2010-05-11 | 2013-01-29 | Demerx, Inc. | Substituted noribogaine |
| US8637648B1 (en) | 2010-06-22 | 2014-01-28 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
| US8741891B1 (en) | 2010-06-22 | 2014-06-03 | Demerx, Inc. | N-substituted noribogaine prodrugs |
| US9586954B2 (en) | 2010-06-22 | 2017-03-07 | Demerx, Inc. | N-substituted noribogaine prodrugs |
| US8802832B2 (en) | 2010-06-22 | 2014-08-12 | Demerx, Inc. | Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier |
| US9358237B2 (en) | 2010-07-23 | 2016-06-07 | Demerx, Inc. | Noribogaine compositions |
| EP2481740B1 (en) | 2011-01-26 | 2015-11-04 | DemeRx, Inc. | Methods and compositions for preparing noribogaine from voacangine |
| US9617274B1 (en) | 2011-08-26 | 2017-04-11 | Demerx, Inc. | Synthetic noribogaine |
| EP2788003A4 (en) | 2011-12-09 | 2015-05-27 | Demerx Inc | Phosphate esters of noribogaine |
| WO2013112673A1 (en) | 2012-01-25 | 2013-08-01 | Demerx, Inc. | Synthetic voacangine |
| US9150584B2 (en) | 2012-01-25 | 2015-10-06 | Demerx, Inc. | Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them |
| WO2014098877A1 (en) | 2012-12-20 | 2014-06-26 | Demerx, Inc. | Substituted noribogaine |
| US9045481B2 (en) | 2012-12-20 | 2015-06-02 | Demerx, Inc. | Substituted noribogaine |
| US8940728B2 (en) | 2012-12-20 | 2015-01-27 | Demerx, Inc. | Substituted noribogaine |
| US10428115B2 (en) | 2013-05-24 | 2019-10-01 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Dynorphin A analogs with bradykinin receptors specificity for modulation of neuropathic pain |
| WO2015195673A2 (en) | 2014-06-18 | 2015-12-23 | Demerx, Inc. | Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996006626A1 (en) * | 1994-08-26 | 1996-03-07 | Lee Nancy M | Analgesic method with dynorphin analogues truncated at the n-terminus |
-
1993
- 1993-06-01 CA CA002137916A patent/CA2137916A1/en not_active Abandoned
- 1993-06-01 JP JP6501537A patent/JPH08501075A/en active Pending
- 1993-06-01 HU HU9403563A patent/HUT70160A/en unknown
- 1993-06-01 RU RU95106651/14A patent/RU95106651A/en unknown
- 1993-06-01 EP EP93914274A patent/EP0652765A4/en not_active Withdrawn
- 1993-06-01 CZ CZ943131A patent/CZ281630B6/en unknown
- 1993-06-01 KR KR1019940704525A patent/KR950701818A/en not_active Withdrawn
- 1993-06-01 WO PCT/US1993/005161 patent/WO1993025217A1/en not_active Ceased
- 1993-06-01 AU AU43990/93A patent/AU4399093A/en not_active Abandoned
- 1993-06-01 FI FI945811A patent/FI945811L/en not_active Application Discontinuation
-
1994
- 1994-12-09 NO NO944778A patent/NO944778L/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO944778L (en) | 1995-02-10 |
| EP0652765A4 (en) | 1997-04-09 |
| CZ313194A3 (en) | 1995-08-16 |
| JPH08501075A (en) | 1996-02-06 |
| EP0652765A1 (en) | 1995-05-17 |
| NO944778D0 (en) | 1994-12-09 |
| HUT70160A (en) | 1995-09-28 |
| FI945811L (en) | 1995-02-06 |
| RU95106651A (en) | 1996-12-27 |
| CA2137916A1 (en) | 1993-12-23 |
| WO1993025217A1 (en) | 1993-12-23 |
| KR950701818A (en) | 1995-05-17 |
| FI945811A0 (en) | 1994-12-09 |
| AU4399093A (en) | 1994-01-04 |
| CZ281630B6 (en) | 1996-11-13 |
| HU9403563D0 (en) | 1995-02-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD | Application lapsed |