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FI945811A7 - Des-Tyr-dynorphin analogs - Google Patents

Des-Tyr-dynorphin analogs Download PDF

Info

Publication number
FI945811A7
FI945811A7 FI945811A FI945811A FI945811A7 FI 945811 A7 FI945811 A7 FI 945811A7 FI 945811 A FI945811 A FI 945811A FI 945811 A FI945811 A FI 945811A FI 945811 A7 FI945811 A7 FI 945811A7
Authority
FI
Finland
Prior art keywords
tyr
des
dynorphin analogs
dynorphin
analogs
Prior art date
Application number
FI945811A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI945811L (en
FI945811A0 (en
Inventor
Nancy M Lee
Horace H Loh
Akira E Takemori
Original Assignee
Des Tyr Dynorphin Partnership
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Des Tyr Dynorphin Partnership filed Critical Des Tyr Dynorphin Partnership
Publication of FI945811A0 publication Critical patent/FI945811A0/en
Publication of FI945811A7 publication Critical patent/FI945811A7/en
Publication of FI945811L publication Critical patent/FI945811L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Addiction (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI945811A 1992-06-12 1993-06-01 Des-Tyr dynorphin analogs FI945811L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89792092A 1992-06-12 1992-06-12
PCT/US1993/005161 WO1993025217A1 (en) 1992-06-12 1993-06-01 Des-tyr dynorphin analogues

Publications (3)

Publication Number Publication Date
FI945811A0 FI945811A0 (en) 1994-12-09
FI945811A7 true FI945811A7 (en) 1995-02-06
FI945811L FI945811L (en) 1995-02-06

Family

ID=25408662

Family Applications (1)

Application Number Title Priority Date Filing Date
FI945811A FI945811L (en) 1992-06-12 1993-06-01 Des-Tyr dynorphin analogs

Country Status (11)

Country Link
EP (1) EP0652765A4 (en)
JP (1) JPH08501075A (en)
KR (1) KR950701818A (en)
AU (1) AU4399093A (en)
CA (1) CA2137916A1 (en)
CZ (1) CZ281630B6 (en)
FI (1) FI945811L (en)
HU (1) HUT70160A (en)
NO (1) NO944778L (en)
RU (1) RU95106651A (en)
WO (1) WO1993025217A1 (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5482930A (en) * 1993-06-09 1996-01-09 The Regents Of The University Of California Anti-inflammatory composition and method with des-Tyr dynorphin and analogues
IL134796A0 (en) 1997-09-04 2001-04-30 Novoneuron Inc Noribogaine in the treatment of pain and drug addiction
US7220737B1 (en) 1997-09-04 2007-05-22 Novoneuron, Inc Noribogaine in the treatment of pain and drug addiction
US6437092B1 (en) 1998-11-06 2002-08-20 Conjuchem, Inc. Conjugates of opioids and endogenous carriers
EP1598365A1 (en) 1999-05-17 2005-11-23 ConjuChem Inc. Protection of endogenous therapeutic peptides
US7601691B2 (en) 1999-05-17 2009-10-13 Conjuchem Biotechnologies Inc. Anti-obesity agents
US6887470B1 (en) 1999-09-10 2005-05-03 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
US6849714B1 (en) 1999-05-17 2005-02-01 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
US6706892B1 (en) 1999-09-07 2004-03-16 Conjuchem, Inc. Pulmonary delivery for bioconjugation
WO2002062844A2 (en) 2001-02-02 2002-08-15 Conjuchem Inc. Long lasting growth hormone releasing factor derivatives
EP1360202B1 (en) 2001-02-16 2008-05-21 ConjuChem Biotechnologies Inc. Long lasting glucagon-like peptide 2 (glp-2) for the treatment of gastrointestinal diseases and disorders
US8765737B1 (en) 2010-05-11 2014-07-01 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US9394294B2 (en) 2010-05-11 2016-07-19 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US8362007B1 (en) 2010-05-11 2013-01-29 Demerx, Inc. Substituted noribogaine
US8637648B1 (en) 2010-06-22 2014-01-28 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US8741891B1 (en) 2010-06-22 2014-06-03 Demerx, Inc. N-substituted noribogaine prodrugs
US9586954B2 (en) 2010-06-22 2017-03-07 Demerx, Inc. N-substituted noribogaine prodrugs
US8802832B2 (en) 2010-06-22 2014-08-12 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US9358237B2 (en) 2010-07-23 2016-06-07 Demerx, Inc. Noribogaine compositions
EP2481740B1 (en) 2011-01-26 2015-11-04 DemeRx, Inc. Methods and compositions for preparing noribogaine from voacangine
US9617274B1 (en) 2011-08-26 2017-04-11 Demerx, Inc. Synthetic noribogaine
EP2788003A4 (en) 2011-12-09 2015-05-27 Demerx Inc Phosphate esters of noribogaine
WO2013112673A1 (en) 2012-01-25 2013-08-01 Demerx, Inc. Synthetic voacangine
US9150584B2 (en) 2012-01-25 2015-10-06 Demerx, Inc. Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them
WO2014098877A1 (en) 2012-12-20 2014-06-26 Demerx, Inc. Substituted noribogaine
US9045481B2 (en) 2012-12-20 2015-06-02 Demerx, Inc. Substituted noribogaine
US8940728B2 (en) 2012-12-20 2015-01-27 Demerx, Inc. Substituted noribogaine
US10428115B2 (en) 2013-05-24 2019-10-01 Arizona Board Of Regents On Behalf Of The University Of Arizona Dynorphin A analogs with bradykinin receptors specificity for modulation of neuropathic pain
WO2015195673A2 (en) 2014-06-18 2015-12-23 Demerx, Inc. Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996006626A1 (en) * 1994-08-26 1996-03-07 Lee Nancy M Analgesic method with dynorphin analogues truncated at the n-terminus

Also Published As

Publication number Publication date
NO944778L (en) 1995-02-10
EP0652765A4 (en) 1997-04-09
CZ313194A3 (en) 1995-08-16
JPH08501075A (en) 1996-02-06
EP0652765A1 (en) 1995-05-17
NO944778D0 (en) 1994-12-09
HUT70160A (en) 1995-09-28
FI945811L (en) 1995-02-06
RU95106651A (en) 1996-12-27
CA2137916A1 (en) 1993-12-23
WO1993025217A1 (en) 1993-12-23
KR950701818A (en) 1995-05-17
FI945811A0 (en) 1994-12-09
AU4399093A (en) 1994-01-04
CZ281630B6 (en) 1996-11-13
HU9403563D0 (en) 1995-02-28

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