FI944727L - Indolijohdannaisia 5-HT1:n kaltaisina agonisteina - Google Patents

Indolijohdannaisia 5-HT1:n kaltaisina agonisteina Download PDF

Info

Publication number: FI944727L
Authority: FI; Finland
Prior art keywords: agonists; indole derivatives; indole; derivatives
Prior art date: 1992-04-10

Application number

FI944727A

Other languages

English (en)

Swedish (sv)

Other versions

FI111255B (fi

FI944727A0 (fi

Inventor

John Eugene Macor

Martin James Wythes

Original Assignee

Pfizer Res & Dev

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-04-10

Filing date

1994-10-07

Publication date

1994-10-07

1994-10-07 Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev

1994-10-07 Publication of FI944727L publication Critical patent/FI944727L/fi

1994-10-07 Publication of FI944727A0 publication Critical patent/FI944727A0/fi

2003-06-30 Application granted granted Critical

2003-06-30 Publication of FI111255B publication Critical patent/FI111255B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Obesity (AREA)
Child & Adolescent Psychology (AREA)
Diabetes (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Addiction (AREA)
Psychiatry (AREA)
Anesthesiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Compositions Of Macromolecular Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

FI944727A 1992-04-10 1994-10-07 Menetelmä terapeuttisesti käyttökelpoisten 3,5-disubstituoitujen indolijohdannaisten valmistamiseksi FI111255B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB929207930A GB9207930D0 (en)	1992-04-10	1992-04-10	Indoles
GB9207930		1992-04-10
PCT/EP1993/000738 WO1993021177A1 (en)	1992-04-10	1993-03-25	Indole derivatives as 5-ht1-like agonists
EP9300738		1993-03-25

Publications (3)

Publication Number	Publication Date
FI944727L true FI944727L (fi)	1994-10-07
FI944727A0 FI944727A0 (fi)	1994-10-07
FI111255B FI111255B (fi)	2003-06-30

Family

ID=10713831

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI944727A FI111255B (fi)	1992-04-10	1994-10-07	Menetelmä terapeuttisesti käyttökelpoisten 3,5-disubstituoitujen indolijohdannaisten valmistamiseksi

Country Status (16)

Country	Link
US (1)	US5639779A (fi)
EP (1)	EP0635014B1 (fi)
JP (1)	JP2784265B2 (fi)
CN (1)	CN1082039A (fi)
AT (1)	ATE133169T1 (fi)
AU (1)	AU3752593A (fi)
CA (1)	CA2131000C (fi)
DE (1)	DE69301357T2 (fi)
DK (1)	DK0635014T3 (fi)
ES (1)	ES2082639T3 (fi)
FI (1)	FI111255B (fi)
GB (1)	GB9207930D0 (fi)
GR (1)	GR3019132T3 (fi)
IL (1)	IL105311A0 (fi)
WO (1)	WO1993021177A1 (fi)
ZA (1)	ZA932534B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5559246A (en) *	1990-10-15	1996-09-24	Pfizer Inc.	Indole derivatives
US5607951A (en) *	1990-10-15	1997-03-04	Pfizer Inc	Indole derivatives
US5559129A (en) *	1990-10-15	1996-09-24	Pfizer Inc	Indole derivatives
US5545644A (en) *	1990-10-15	1996-08-13	Pfizer Inc.	Indole derivatives
US5578612A (en) *	1990-10-15	1996-11-26	Pfizer Inc.	Indole derivatives
DK0716649T3 (da) *	1993-08-31	1999-02-08	Pfizer	5-Arylindolderivater
GB9417310D0 (en)	1994-08-27	1994-10-19	Pfizer Ltd	Therapeutic agents
GB9420503D0 (en) *	1994-10-11	1994-11-23	Pfizer Ltd	Therapeutic agents
GB9420529D0 (en)	1994-10-12	1994-11-30	Pfizer Ltd	Indoles
US5994352A (en) *	1998-11-13	1999-11-30	Pfizer Inc.	5-arylindole derivatives
GB9923314D0 (en) *	1999-10-01	1999-12-08	Pfizer Ltd	Acylation process
EP1132389A1 (en) *	2000-03-06	2001-09-12	Vernalis Research Limited	New aza-indolyl derivatives for the treatment of obesity
US8754239B2 (en)	2010-01-19	2014-06-17	Sms Pharmaceuticals Limited	Process for preparing eletriptan hydrobromide having α-form

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA795239B (en) *	1978-10-12	1980-11-26	Glaxo Group Ltd	Heterocyclic compounds
ZA815541B (en) *	1980-08-12	1983-03-30	Glaxo Group Ltd	Heterocyclic compounds
GB2083463B (en) *	1980-08-12	1984-05-10	Glaxo Group Ltd	Heterocyclic compounds
GB8600397D0 (en) *	1986-01-08	1986-02-12	Glaxo Group Ltd	Chemical compounds
GB8719167D0 (en) *	1987-08-13	1987-09-23	Glaxo Group Ltd	Chemical compounds
GB8724912D0 (en) *	1987-10-23	1987-11-25	Wellcome Found	Indole derivatives
GB8819024D0 (en) *	1988-08-10	1988-09-14	Glaxo Group Ltd	Chemical compounds
IL96891A0 (en) *	1990-01-17	1992-03-29	Merck Sharp & Dohme	Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them
MC2210A1 (fr) *	1990-06-07	1992-11-26	Wellcome Found	Composes heterocycliques therapeutiques,leur utilisation et procede pour les preparer
ES2104733T3 (es) *	1990-10-15	1997-10-16	Pfizer	Derivados de indol.
US5208248A (en) *	1991-01-11	1993-05-04	Merck Sharpe & Dohme, Ltd.	Indazole-substituted five-membered heteroaromatic compounds
SK278998B6 (sk) *	1991-02-01	1998-05-06	Merck Sharp & Dohme Limited	Deriváty imidazolu, triazolu a tetrazolu, spôsob i
US5409941A (en) *	1992-02-03	1995-04-25	Pfizer Inc.	5-heteroyl indole derivatives

1992
- 1992-04-10 GB GB929207930A patent/GB9207930D0/en active Pending
1993
- 1993-03-25 DE DE69301357T patent/DE69301357T2/de not_active Expired - Fee Related
- 1993-03-25 CA CA002131000A patent/CA2131000C/en not_active Expired - Fee Related
- 1993-03-25 AT AT93906620T patent/ATE133169T1/de not_active IP Right Cessation
- 1993-03-25 ES ES93906620T patent/ES2082639T3/es not_active Expired - Lifetime
- 1993-03-25 US US08/313,106 patent/US5639779A/en not_active Expired - Fee Related
- 1993-03-25 DK DK93906620.5T patent/DK0635014T3/da active
- 1993-03-25 EP EP93906620A patent/EP0635014B1/en not_active Expired - Lifetime
- 1993-03-25 AU AU37525/93A patent/AU3752593A/en not_active Abandoned
- 1993-03-25 WO PCT/EP1993/000738 patent/WO1993021177A1/en not_active Ceased
- 1993-03-25 JP JP5517929A patent/JP2784265B2/ja not_active Expired - Fee Related
- 1993-04-05 IL IL105311A patent/IL105311A0/xx unknown
- 1993-04-08 ZA ZA932534A patent/ZA932534B/xx unknown
- 1993-04-10 CN CN93105712A patent/CN1082039A/zh active Pending
1994
- 1994-10-07 FI FI944727A patent/FI111255B/fi not_active IP Right Cessation
1996
- 1996-02-28 GR GR960400556T patent/GR3019132T3/el unknown

Also Published As

Publication number	Publication date
GB9207930D0 (en)	1992-05-27
JP2784265B2 (ja)	1998-08-06
US5639779A (en)	1997-06-17
ES2082639T3 (es)	1996-03-16
EP0635014A1 (en)	1995-01-25
AU3752593A (en)	1993-11-18
CN1082039A (zh)	1994-02-16
JPH07505402A (ja)	1995-06-15
IL105311A0 (en)	1993-08-18
GR3019132T3 (en)	1996-05-31
DE69301357T2 (de)	1996-06-13
FI111255B (fi)	2003-06-30
ATE133169T1 (de)	1996-02-15
WO1993021177A1 (en)	1993-10-28
CA2131000C (en)	1998-09-22
CA2131000A1 (en)	1993-10-28
ZA932534B (en)	1994-10-08
FI944727A0 (fi)	1994-10-07
DK0635014T3 (da)	1996-02-12
EP0635014B1 (en)	1996-01-17
DE69301357D1 (de)	1996-02-29

Publication	Publication Date	Title
KR950700906A (ko)	1995-02-20	5-ht1 작동약으로서의 인돌 유도체(indole derivatives as 5-ht1 agonists)
FI944805A7 (fi)	1994-10-12	Indolijohdannaisia 5-HT1-kaltaisina agonisteina
FI942395A7 (fi)	1994-05-24	Indolijohdannaiset
FI933551A7 (fi)	1993-08-11	5-heteroyyli-indolijohdannaisia
DK0393936T3 (da)	1995-06-26	3-substituerede 2-oxindolderivater som antiinflammatoriske midler
DK0516349T3 (da)	1995-11-06	2-hydroxy-2-phenylethylamin-derivater som beta-3-adrenoceptoragonister
NO301879B1 (no)	1997-12-22	Indol-derivater
FI944969A7 (fi)	1995-04-23	Indolijohdannaisia
FI970310L (fi)	1997-01-24	4-indolijohdannaiset serotoniinin vaikuttaja- ja vastavaikuttaja-aineina
FI962969L (fi)	1996-07-25	Indolijohdannaisia 5-HT1:n agonisteina
FI961628A0 (fi)	1996-04-12	Indolijohdannaisia NMDA-antagonisteina
NO893078D0 (no)	1989-07-28	Indolderivater.
DK0411150T3 (da)	1996-12-16	Indolderivater
DE69212058D1 (de)	1996-08-14	Indol-Derivate
FI944727L (fi)	1994-10-07	Indolijohdannaisia 5-HT1:n kaltaisina agonisteina
NO954287L (no)	1995-10-26	Anvendelse av indolderivater som 5-HT1 agonister
DE59005241D1 (de)	1994-05-11	Indolderivate.
FI950568A7 (fi)	1995-08-11	5-heteroaryyli-indolijohdannaiset
FI925774A7 (fi)	1993-06-21	Indolijohdannaiset
DE69320653D1 (de)	1998-10-01	Tetrahydrocarbazolderivate als 5-ht1-ähnliche agonisten
FI900641A7 (fi)	1990-08-11	Indolijohdokset
FI971492L (fi)	1997-04-10	Indolijohdannaiset 5-HT1-tyyppisinä agonisteina
DK647289D0 (da)	1989-12-19	Annellerede indol-derivater
FI960730L (fi)	1996-02-16	Indolijohdannaiset 5alfa-reduktaasi-1-inhibiittoreina
DK0725061T3 (da)	2000-10-02	Substituerede indolderivater

Legal Events

Date	Code	Title	Description
2006-09-30	MA	Patent expired