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FI944606A7 - Process for the preparation of 4-pyridyl and 4-piperidinyl imidazoles useful as intermediates in the synthesis of histamine receptor antagonists - Google Patents

Process for the preparation of 4-pyridyl and 4-piperidinyl imidazoles useful as intermediates in the synthesis of histamine receptor antagonists Download PDF

Info

Publication number
FI944606A7
FI944606A7 FI944606A FI944606A FI944606A7 FI 944606 A7 FI944606 A7 FI 944606A7 FI 944606 A FI944606 A FI 944606A FI 944606 A FI944606 A FI 944606A FI 944606 A7 FI944606 A7 FI 944606A7
Authority
FI
Finland
Prior art keywords
piperidinyl
pyridyl
intermediates
synthesis
preparation
Prior art date
Application number
FI944606A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI944606L (en
FI944606A0 (en
Inventor
Graham J Durant
Amin M Khan
Original Assignee
Univ Toledo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Toledo filed Critical Univ Toledo
Publication of FI944606A0 publication Critical patent/FI944606A0/en
Publication of FI944606L publication Critical patent/FI944606L/en
Publication of FI944606A7 publication Critical patent/FI944606A7/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI944606A 1992-04-01 1993-03-31 Process for the preparation of 4-pyridyl and 4-piperidinyl imidazoles useful as intermediates in the synthesis of histamine receptor antagonists FI944606A7 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/862,658 US5380858A (en) 1992-04-01 1992-04-01 Process for the preparation of intermediates useful for the synthesis of histamine receptor antagonists
PCT/US1993/003105 WO1993020062A1 (en) 1992-04-01 1993-03-31 Process for the preparation of 4-pyridyl- and 4-piperidinylimidazoles useful as intermediates for the synthesis of histamine receptor antagonists

Publications (3)

Publication Number Publication Date
FI944606A0 FI944606A0 (en) 1994-10-03
FI944606L FI944606L (en) 1994-11-30
FI944606A7 true FI944606A7 (en) 1994-11-30

Family

ID=25338980

Family Applications (1)

Application Number Title Priority Date Filing Date
FI944606A FI944606A7 (en) 1992-04-01 1993-03-31 Process for the preparation of 4-pyridyl and 4-piperidinyl imidazoles useful as intermediates in the synthesis of histamine receptor antagonists

Country Status (13)

Country Link
US (2) US5380858A (en)
EP (1) EP0633883A1 (en)
JP (1) JPH07509220A (en)
KR (1) KR950700899A (en)
AU (1) AU3944693A (en)
BR (1) BR9306191A (en)
CA (1) CA2133460A1 (en)
FI (1) FI944606A7 (en)
HU (1) HU9402826D0 (en)
NO (1) NO943688L (en)
RU (1) RU94045838A (en)
SK (1) SK118894A3 (en)
WO (1) WO1993020062A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5817823A (en) * 1997-04-17 1998-10-06 Sepracor Inc. Method for synthesizing 2-substituted imidazoles
US6887870B1 (en) * 1999-10-12 2005-05-03 Bristol-Myers Squibb Company Heterocyclic sodium/proton exchange inhibitors and method
EP1707203A1 (en) 2005-04-01 2006-10-04 Bioprojet Treatment of parkinson's disease obstructive sleep apnea, dementia with lewy bodies, vascular dementia with non-imidazole alkylamines histamine H3- receptor ligands
EP1717233A1 (en) * 2005-04-29 2006-11-02 Bioprojet Histamine H3-receptor ligands and their therapeutic application
EP1717235A3 (en) 2005-04-29 2007-02-28 Bioprojet Phenoxypropylpiperidines and -pyrrolidines and their use as histamine H3-receptor ligands
WO2013151982A1 (en) 2012-04-03 2013-10-10 Arena Pharmaceuticals, Inc. Methods and compounds useful in treating pruritus, and methods for identifying such compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2579596B1 (en) * 1985-03-26 1987-11-20 Inst Nat Sante Rech Med (IMIDAZOLYL-4) PIPERIDINES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2671083B1 (en) * 1990-12-31 1994-12-23 Inst Nat Sante Rech Med NEWS 4- (4-IMIDAZOLYL) PIPERIDINES SUBSTITUTED IN 1, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATIONS.
FR2674855B1 (en) * 1991-04-03 1994-01-14 Synthelabo PIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.

Also Published As

Publication number Publication date
BR9306191A (en) 1998-06-30
US5663350A (en) 1997-09-02
FI944606L (en) 1994-11-30
RU94045838A (en) 1996-08-10
HU9402826D0 (en) 1994-12-28
AU3944693A (en) 1993-11-08
WO1993020062A1 (en) 1993-10-14
NO943688L (en) 1994-11-25
SK118894A3 (en) 1995-07-11
US5380858A (en) 1995-01-10
FI944606A0 (en) 1994-10-03
KR950700899A (en) 1995-02-20
JPH07509220A (en) 1995-10-12
CA2133460A1 (en) 1993-10-14
NO943688D0 (en) 1994-10-03
EP0633883A1 (en) 1995-01-18

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Legal Events

Date Code Title Description
FD Application lapsed