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FI944575L - Decorin fragments and methods for inhibiting cellular regulatory factors - Google Patents

Decorin fragments and methods for inhibiting cellular regulatory factors Download PDF

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Publication number
FI944575L
FI944575L FI944575A FI944575A FI944575L FI 944575 L FI944575 L FI 944575L FI 944575 A FI944575 A FI 944575A FI 944575 A FI944575 A FI 944575A FI 944575 L FI944575 L FI 944575L
Authority
FI
Finland
Prior art keywords
methods
regulatory factors
inhibiting cellular
cellular regulatory
decorin
Prior art date
Application number
FI944575A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI944575A7 (en
FI944575A0 (en
Inventor
Erkki I Ruoslahti
Michael D Pierschbacher
Jose Cardenas
William Craig
Daniel G Mullen
Original Assignee
Jolla Cancer Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jolla Cancer Res Found filed Critical Jolla Cancer Res Found
Publication of FI944575A0 publication Critical patent/FI944575A0/en
Publication of FI944575A7 publication Critical patent/FI944575A7/en
Publication of FI944575L publication Critical patent/FI944575L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725Proteoglycans, e.g. aggreccan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/20Fusion polypeptide containing a tag with affinity for a non-protein ligand
    • C07K2319/24Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a MBP (maltose binding protein)-tag
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/73Fusion polypeptide containing domain for protein-protein interaction containing coiled-coiled motif (leucine zippers)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
FI944575A 1992-04-03 1993-04-02 Decorin fragments and methods for inhibiting cellular regulatory factors FI944575L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86565292A 1992-04-03 1992-04-03
PCT/US1993/003171 WO1993020202A1 (en) 1992-04-03 1993-04-02 Decorin fragments and methods of inhibiting cell regulatory factors

Publications (3)

Publication Number Publication Date
FI944575A0 FI944575A0 (en) 1994-09-30
FI944575A7 FI944575A7 (en) 1994-11-29
FI944575L true FI944575L (en) 1994-11-29

Family

ID=25345963

Family Applications (1)

Application Number Title Priority Date Filing Date
FI944575A FI944575L (en) 1992-04-03 1993-04-02 Decorin fragments and methods for inhibiting cellular regulatory factors

Country Status (7)

Country Link
EP (1) EP0636175A1 (en)
JP (1) JPH07508403A (en)
AU (1) AU679178B2 (en)
CA (1) CA2132859A1 (en)
FI (1) FI944575L (en)
NO (1) NO943654L (en)
WO (1) WO1993020202A1 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0900804A2 (en) * 1993-03-01 1999-03-10 Glycan Pharmaceuticals, Inc. Analogs for specific oligosaccharide-protein interactions and uses therefor
US5567807A (en) * 1994-07-08 1996-10-22 La Jolla Cancer Research Foundation Processes for the purification of human recombinant decorin and the detection of guanidinium ions
JP2008503205A (en) * 2004-05-31 2008-02-07 ナショナル ユニヴァーシティ オブ シンガポール Peptide derived from decorin leucine rich repeat and use thereof
ATE461214T1 (en) * 2005-09-05 2010-04-15 Immatics Biotechnologies Gmbh TUMOR-ASSOCIATED PEPTIDES THAT BIND TO DIFFERENT CLASS II HUMAN LEUCOCYTE ANTIGENS
ES2283212B1 (en) * 2006-03-31 2008-08-16 Lipotec S.A. USEFUL SYNTHETIC PEPTIDES IN THE TREATMENT OF SKIN AND ITS USE IN COSMETIC OR DERMOPHARMACEUTICAL COMPOSITIONS.
HU0700024D0 (en) * 2007-01-11 2007-03-28 Mta Szegedi Biolog Koezpont Use of enhancers in biglycan activuty in the preparation of pharmaceutical compositions having utility in cardiac diseases
US9359633B2 (en) * 2007-11-05 2016-06-07 Nordic Bioscience A/S Biochemical markers for CVD risk assessment
US20120238727A1 (en) * 2011-03-14 2012-09-20 Catalent Pharma Solutions Llc Decorin compositions and use thereof
BR112021023913A2 (en) * 2019-06-06 2022-01-25 Aroa Biosurgery Ltd Bioactive agents and methods related to them
WO2024218311A1 (en) 2023-04-21 2024-10-24 Pulsesight Therapeutics Decorin-based compositions for repair and regeneration of retinal pigment epithelium

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991010727A1 (en) * 1990-01-22 1991-07-25 La Jolla Cancer Research Foundation Inhibitors of cell regulatory factors

Also Published As

Publication number Publication date
EP0636175A1 (en) 1995-02-01
FI944575A7 (en) 1994-11-29
CA2132859A1 (en) 1993-10-14
NO943654D0 (en) 1994-09-30
AU4025793A (en) 1993-11-08
JPH07508403A (en) 1995-09-21
AU679178B2 (en) 1997-06-26
NO943654L (en) 1994-12-05
WO1993020202A1 (en) 1993-10-14
FI944575A0 (en) 1994-09-30

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