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FI944412L - Proteiinin puhdistus - Google Patents

Proteiinin puhdistus Download PDF

Info

Publication number
FI944412L
FI944412L FI944412A FI944412A FI944412L FI 944412 L FI944412 L FI 944412L FI 944412 A FI944412 A FI 944412A FI 944412 A FI944412 A FI 944412A FI 944412 L FI944412 L FI 944412L
Authority
FI
Finland
Prior art keywords
protein purification
purification
protein
Prior art date
Application number
FI944412A
Other languages
English (en)
Swedish (sv)
Other versions
FI109202B (fi
FI944412A0 (fi
Inventor
Gail Folena-Wasserman
John H O'grady
Thomas M Smith
John Lifter
Original Assignee
Smithkline Beecham Corp
T Cell Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp, T Cell Sciences Inc filed Critical Smithkline Beecham Corp
Publication of FI944412L publication Critical patent/FI944412L/fi
Publication of FI944412A0 publication Critical patent/FI944412A0/fi
Application granted granted Critical
Publication of FI109202B publication Critical patent/FI109202B/fi

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596Molecules with a "CD"-designation not provided for elsewhere
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/32Bonded phase chromatography
    • B01D15/325Reversed phase
    • B01D15/327Reversed phase with hydrophobic interaction
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/34Size-selective separation, e.g. size-exclusion chromatography; Gel filtration; Permeation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361Ion-exchange
    • B01D15/362Cation-exchange
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/36Selective adsorption, e.g. chromatography characterised by the separation mechanism involving ionic interaction, e.g. ion-exchange, ion-pair, ion-suppression or ion-exclusion
    • B01D15/361Ion-exchange
    • B01D15/363Anion-exchange

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI944412A 1992-03-24 1994-09-23 Proteiinin puhdistus FI109202B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/857,022 US5252216A (en) 1992-03-24 1992-03-24 Protein purification
US85702292 1992-03-24
US9302732 1993-03-24
PCT/US1993/002732 WO1993018835A1 (en) 1992-03-24 1993-03-24 Protein purification

Publications (3)

Publication Number Publication Date
FI944412L true FI944412L (fi) 1994-09-23
FI944412A0 FI944412A0 (fi) 1994-09-23
FI109202B FI109202B (fi) 2002-06-14

Family

ID=25324998

Family Applications (1)

Application Number Title Priority Date Filing Date
FI944412A FI109202B (fi) 1992-03-24 1994-09-23 Proteiinin puhdistus

Country Status (19)

Country Link
US (1) US5252216A (fi)
EP (1) EP0643608B1 (fi)
JP (1) JP3335629B2 (fi)
KR (1) KR100241172B1 (fi)
AT (1) ATE193839T1 (fi)
AU (1) AU659936B2 (fi)
CA (1) CA2132533C (fi)
DE (1) DE69328864T2 (fi)
DK (1) DK0643608T3 (fi)
ES (1) ES2149206T3 (fi)
FI (1) FI109202B (fi)
GR (1) GR3034332T3 (fi)
MX (1) MX9301655A (fi)
NO (1) NO310855B1 (fi)
NZ (1) NZ251601A (fi)
PT (1) PT643608E (fi)
TW (1) TW321651B (fi)
WO (1) WO1993018835A1 (fi)
ZA (1) ZA932015B (fi)

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US6395888B1 (en) * 1996-02-01 2002-05-28 Gilead Sciences, Inc. High affinity nucleic acid ligands of complement system proteins
DE4331358A1 (de) * 1992-10-12 1994-04-14 Braun Melsungen Ag Verfahren zur quantitativen selektiven Entfernung oder präparativen Gewinnung von Tumor-Nekrose-Faktor (TNF) oder/und Lipopolysacchariden (LPS) aus wäßrigen Flüssigkeiten
ATE213639T1 (de) * 1993-07-09 2002-03-15 Avant Immunotherapeutics Inc Proteinreinigung
US5679546A (en) * 1993-09-24 1997-10-21 Cytomed, Inc. Chimeric proteins which block complement activation
US5429746A (en) * 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
DE19549420A1 (de) * 1995-04-27 1997-09-18 Braun Melsungen Ag Verfahren zur simultanen extrakorporalen Elimination von Tumor-Nekrose Faktor alpha (TNF alpha) und bakteriellen Lipopolysacchariden (LPS) aus Vollblut oder/und Blutplasma
EP1300679A3 (en) * 1995-06-26 2004-04-14 Perseptive Biosystems, Inc. Molecular selection and analysis
JP3737516B2 (ja) * 1995-06-26 2006-01-18 パーセプティブ バイオシステムズ,インコーポレーテッド 高速自動化連続流、多次元分子選別および分析
GB9515196D0 (en) * 1995-07-25 1995-09-20 Matthey Rustenburg Refines Interseparation of platignum group metals
CA2294749C (en) * 1997-06-27 2007-01-02 Life Technologies, Inc. One step device and process for concentration and purification of biological molecules
US5993653C1 (en) * 1997-08-11 2001-11-06 Phenomenex Composition and column used in hplc
US6869796B2 (en) * 1997-08-26 2005-03-22 Avaris Ab Method of introducing organic molecules into target cells
US20070122904A1 (en) * 2000-09-29 2007-05-31 Unisearch Limited Method and apparatus for culturing cells
US6855263B2 (en) * 2002-07-23 2005-02-15 Nuvue Technologies, Inc. Rapid process for purification and concentration of plasmin
DE10255508A1 (de) * 2002-11-27 2004-06-17 Forschungszentrum Jülich GmbH Verfahren zur Kultivierung von Zellen zur Produktion von Substanzen
US6913695B2 (en) * 2003-07-08 2005-07-05 Bayer Healthcare Llc Sanitization of chromatographic media
WO2005012349A2 (en) * 2003-08-01 2005-02-10 Lorantis Limited Chromatographic process for the purification of notch ligands
US7329353B2 (en) * 2004-01-23 2008-02-12 Amgen Inc. LC/MS method of analyzing high molecular weight proteins
US7803931B2 (en) 2004-02-12 2010-09-28 Archemix Corp. Aptamer therapeutics useful in the treatment of complement-related disorders
ATE443870T1 (de) * 2004-07-20 2009-10-15 Symphogen As Verfahren zur charakterisierung einer polyklonalen zellinie
US20090042274A1 (en) * 2004-07-27 2009-02-12 Genomidea Inc. Method of Purifying Virus Envelope
CN101039964B (zh) * 2004-08-12 2012-11-14 利普生技术有限公司 带电多糖的分级
EP1738763A1 (en) 2005-06-30 2007-01-03 AVANT Immunotherapeutics, Inc. Use of complement inhibitory proteins to treat spinal cord injury
WO2007053235A1 (en) * 2005-11-04 2007-05-10 Sachem, Inc. Cation-exchange displacement chromatography process and cationic organic compounds for use as displacer compounds in cation-exchange displacement chromatography process
DK1991275T3 (en) * 2006-03-08 2014-12-08 Archemix Llc Complement aptamers AND ANTI-C5 AGENTS FOR USE IN THE TREATMENT OF EYE DISEASES
US20100222560A1 (en) 2009-03-02 2010-09-02 Zymo Research Corporation Universal column
EP2493922B1 (en) 2009-10-26 2017-02-15 F. Hoffmann-La Roche AG Method for the production of a glycosylated immunoglobulin
EP2616092B1 (en) 2010-09-15 2018-01-24 Celldex Therapeutics, Inc. Treatment of chronic nephropathies using soluble complement receptor type i (scr1)
EP2625263B1 (en) 2010-10-08 2020-03-11 Terumo BCT, Inc. Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system
BR112013010098A2 (pt) 2010-10-27 2017-06-13 Celldex Therapeutics Inc método para melhorar a função de transplante usando um receptor do complemento solúvel tipo i (scr1)
CN106715676A (zh) 2014-09-26 2017-05-24 泰尔茂比司特公司 按计划供养
JP7034949B2 (ja) 2016-05-25 2022-03-14 テルモ ビーシーティー、インコーポレーテッド 細胞の増殖
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
EP3656841A1 (en) 2017-03-31 2020-05-27 Terumo BCT, Inc. Cell expansion
WO2023240322A1 (en) * 2022-06-17 2023-12-21 CSL Innovation Pty Ltd Purification of soluble complement receptor and variants thereof

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2319495C2 (de) * 1973-04-17 1985-01-10 Yeda Research And Development Co., Ltd., Rehovot Verfahren zum selektiven, reversiblen Binden von Biomolekülen an ein Adsorbens in einer chromatographischen Säule
US4000098A (en) * 1974-08-16 1976-12-28 Palo Alto Medical Research Foundation Separation of proteins by hydrophobic adsorption
DE3149360A1 (de) * 1981-12-12 1983-06-16 Biotest-Serum-Institut Gmbh, 6000 Frankfurt "verfahren zur reinigung und/oder phytohaemagglutinin-abtrennung von human-interleukin-2"
US4920196A (en) * 1982-07-30 1990-04-24 Genentech, Inc. Human lymphotoxin
US4908434A (en) * 1984-04-25 1990-03-13 Sloan-Kettering Institute For Cancer Research Process for preparing purified interleukin-2
US4743680A (en) * 1985-02-01 1988-05-10 New York University Method for purifying antihemophilic factor
US4894439A (en) * 1986-05-22 1990-01-16 Cetus Corporation N-terminal derivatives of tumor necrosis factor purified by microporous PTFE membranes
AU597924B2 (en) * 1985-12-11 1990-06-14 Natinco Nv Solubilization of protein aggregates
US4770781A (en) * 1986-03-03 1988-09-13 Merck & Co., Inc. Purification of human interleukin-1 species
US4771128A (en) * 1986-10-10 1988-09-13 Cetus Corporation Method of purifying toxin conjugates using hydrophobic interaction chromatography
AU609824B2 (en) * 1987-06-15 1991-05-09 Southern Cross Biotech Pty Ltd. Production of proteins in active forms
US4981799A (en) * 1987-08-21 1991-01-01 Takeda Chemical Industries, Ltd. Acylamino acid racemase, production and use thereof
US4765903A (en) * 1987-10-06 1988-08-23 Interferon Sciences, Inc. Purification of monomeric interferon
US5159063A (en) * 1989-02-02 1992-10-27 The United States Of America As Represented By The Department Of Health And Human Services Isolation and characterization of a 120 kda glycoprotein plasma
US5030352A (en) * 1990-01-25 1991-07-09 Purdue Research Foundation Coated media for chromatography

Also Published As

Publication number Publication date
ATE193839T1 (de) 2000-06-15
KR950700779A (ko) 1995-02-20
EP0643608A1 (en) 1995-03-22
EP0643608B1 (en) 2000-06-14
KR100241172B1 (ko) 2000-02-01
JP3335629B2 (ja) 2002-10-21
NO310855B1 (no) 2001-09-10
ES2149206T3 (es) 2000-11-01
FI109202B (fi) 2002-06-14
MX9301655A (es) 1994-03-31
DE69328864T2 (de) 2000-12-14
PT643608E (pt) 2000-11-30
US5252216A (en) 1993-10-12
TW321651B (fi) 1997-12-01
CA2132533A1 (en) 1993-09-30
AU3932493A (en) 1993-10-21
FI944412A0 (fi) 1994-09-23
DE69328864D1 (de) 2000-07-20
JPH07505469A (ja) 1995-06-15
NO943546L (no) 1994-11-23
EP0643608A4 (en) 1997-11-26
AU659936B2 (en) 1995-06-01
DK0643608T3 (da) 2000-10-02
NO943546D0 (no) 1994-09-23
ZA932015B (en) 1994-09-21
WO1993018835A1 (en) 1993-09-30
GR3034332T3 (en) 2000-12-29
NZ251601A (en) 1997-03-24
CA2132533C (en) 2004-01-13

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Legal Events

Date Code Title Description
HC Name/ company changed in application

Owner name: SMITHKLINE BEECHAM CORPORATION

MA Patent expired