FI933165A7 - NEW PHOSPHOLIC PYDRIDE DERIVATIVES - Google Patents

NEW PHOSPHOLIC PYDRIDE DERIVATIVES

Info

Publication number: FI933165A7
Authority: FI; Finland
Prior art keywords: pydride; phospholic; derivatives; new; pydride derivatives
Prior art date: 1992-07-11

Application number

FI933165A

Other languages

Finnish (fi)

Other versions

FI933165A0 (en

FI111262B (en

Inventor

Gerhard Noessner

Bernhard Kutscher

Juergen Engel

Wolfgang Schumacher

Jurij Stekar

Peter Hilgard

Original Assignee

Asta Medica Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-07-11

Filing date

1993-07-09

Publication date

1994-01-12

1993-07-09 Application filed by Asta Medica Ag filed Critical Asta Medica Ag

1993-07-09 Publication of FI933165A0 publication Critical patent/FI933165A0/en

1994-01-12 Publication of FI933165A7 publication Critical patent/FI933165A7/en

2003-06-30 Application granted granted Critical

2003-06-30 Publication of FI111262B publication Critical patent/FI111262B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/06—Phosphorus compounds without P—C bonds
- C07F9/08—Esters of oxyacids of phosphorus
- C07F9/09—Esters of phosphoric acids
- C07F9/10—Phosphatides, e.g. lecithin
- C07F9/106—Adducts, complexes, salts of phosphatides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/5532—Seven-(or more) membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/576—Six-membered rings
- C07F9/59—Hydrogenated pyridine rings

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Tropical Medicine & Parasitology (AREA)
Physical Education & Sports Medicine (AREA)
Immunology (AREA)
Dermatology (AREA)
Orthopedic Medicine & Surgery (AREA)
AIDS & HIV (AREA)
Rheumatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Inorganic Compounds Of Heavy Metals (AREA)

FI933165A 1992-07-11 1993-07-09 Process for the preparation of therapeutically useful phospholipid derivatives FI111262B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE4222910A DE4222910A1 (en)	1992-07-11	1992-07-11	New phospholipid derivatives
DE4222910		1992-07-11

Publications (3)

Publication Number	Publication Date
FI933165A0 FI933165A0 (en)	1993-07-09
FI933165A7 true FI933165A7 (en)	1994-01-12
FI111262B FI111262B (en)	2003-06-30

Family

ID=6463031

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI933165A FI111262B (en)	1992-07-11	1993-07-09	Process for the preparation of therapeutically useful phospholipid derivatives

Country Status (31)

Country	Link
EP (1)	EP0579939B1 (en)
JP (1)	JP3311431B2 (en)
KR (1)	KR100297180B1 (en)
CN (1)	CN1039012C (en)
AT (1)	ATE176477T1 (en)
AU (1)	AU664101B2 (en)
BR (1)	BR9302809A (en)
CA (2)	CA2511753C (en)
CZ (1)	CZ290863B6 (en)
DE (2)	DE4222910A1 (en)
DK (1)	DK0579939T3 (en)
EE (1)	EE03140B1 (en)
ES (1)	ES2129053T3 (en)
FI (1)	FI111262B (en)
GR (1)	GR3029602T3 (en)
HR (1)	HRP931046B1 (en)
HU (1)	HU218783B (en)
IL (1)	IL106289A (en)
LT (1)	LT3113B (en)
LV (1)	LV10870B (en)
MX (1)	MX9304133A (en)
NO (1)	NO306468B1 (en)
PL (3)	PL173388B1 (en)
RU (1)	RU2108336C1 (en)
SG (1)	SG46249A1 (en)
SI (1)	SI9300365B (en)
SK (1)	SK283827B6 (en)
TW (1)	TW304956B (en)
UA (1)	UA40567C2 (en)
YU (1)	YU49079B (en)
ZA (1)	ZA934971B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP5475234B2 (en)	2005-01-21	2014-04-16	アステックス・セラピューティクス・リミテッド	Pharmaceutical compounds
AR058397A1 (en)	2005-12-19	2008-01-30	Zentaris Gmbh	DERIVATIVES OF ALQUILFOSFOLIPIDOS WITH REDUCED CYTOTOXICITY AND USES OF THE SAME
EP1800684A1 (en) *	2005-12-20	2007-06-27	Zentaris GmbH	Novel alkyl phospholipid derivatives and uses thereof
EP1869981A1 (en) *	2006-06-21	2007-12-26	Staatliches Weinbauinstitut Freiburg	Alkylphospholipids and lysophospholipids for controlling plant pathogens
WO2008044045A1 (en)	2006-10-12	2008-04-17	Astex Therapeutics Limited	Pharmaceutical combinations
EP2073803B1 (en)	2006-10-12	2018-09-19	Astex Therapeutics Limited	Pharmaceutical combinations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0050327B1 (en) *	1980-10-21	1984-06-20	Roche Diagnostics GmbH	Phospholipids that contain sulphur, process for their preparation and medicines containing these compounds
JPS5984824A (en) *	1982-11-08	1984-05-16	Takeda Chem Ind Ltd	Antitumor agent
DE3530767A1 (en) *	1985-08-28	1987-03-12	Max Planck Gesellschaft	AGENT AGAINST MULTIPLE Sclerosis
CA1338627C (en) *	1985-12-04	1996-10-01	Hansjorg Eibl	Pharmaceuticals based on phosphoric acid esters for use in tumor therapy, and process for their preparation
ES2036210T3 (en) *	1986-07-14	1993-05-16	Nippon Chemiphar Co., Ltd.	A PROCEDURE FOR THE PREPARATION OF A GLYCEROL DERIVATIVE.
DE3881925T2 (en) *	1987-03-24	1994-01-27	Nippon Chemiphar Co	Glycerol derivatives and anti-hypertensive agent.
DE3906952A1 (en) *	1989-03-04	1990-09-06	Boehringer Mannheim Gmbh	(3- (C (DOWN ARROW)) (DOWN ARROW) (DOWN ARROW) 6 (DOWN ARROW) -C (DOWN ARROW) 1 (DOWN ARROW) (DOWN ARROW) 8 (DOWN ARROW)) ALKANSULFINYL AND 2 SULPHONE -METHOXYMETHYL-PROPYL) - (2-TRIMETHYLAMMONIO-ETHYL) PHOSPHATES, METHOD FOR PRODUCING THE MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS
DE3942933A1 (en) *	1989-12-23	1991-06-27	Boehringer Mannheim Gmbh	USE OF ALKYLPHOSPHOLIPIDES AS ANTIVIRAL MEDICINAL PRODUCTS AND NEW PHOSPHOLIPID DERIVATIVES
DE4114586A1 (en) *	1991-05-04	1992-11-05	Boehringer Mannheim Gmbh	MEDICINAL PRODUCTS CONTAINING AZACYCLODIPHOSPHONIC ACID DERIVATIVES, NEW AZACYCLODIPHOSPHONIC ACID DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF

1992
- 1992-07-11 DE DE4222910A patent/DE4222910A1/en not_active Ceased
1993
- 1993-06-01 TW TW082104345A patent/TW304956B/zh not_active IP Right Cessation
- 1993-06-03 ES ES93108904T patent/ES2129053T3/en not_active Expired - Lifetime
- 1993-06-03 AT AT93108904T patent/ATE176477T1/en active
- 1993-06-03 SG SG1996001626A patent/SG46249A1/en unknown
- 1993-06-03 DE DE59309355T patent/DE59309355D1/en not_active Expired - Lifetime
- 1993-06-03 EP EP93108904A patent/EP0579939B1/en not_active Expired - Lifetime
- 1993-06-03 DK DK93108904T patent/DK0579939T3/en active
- 1993-06-04 LT LTIP620A patent/LT3113B/en not_active IP Right Cessation
- 1993-06-23 CZ CZ19931249A patent/CZ290863B6/en not_active IP Right Cessation
- 1993-06-28 SK SK670-93A patent/SK283827B6/en not_active IP Right Cessation
- 1993-07-06 YU YU47393A patent/YU49079B/en unknown
- 1993-07-08 PL PL93299624A patent/PL173388B1/en unknown
- 1993-07-08 PL PL93318680A patent/PL175607B1/en unknown
- 1993-07-08 NO NO932502A patent/NO306468B1/en not_active IP Right Cessation
- 1993-07-08 PL PL93318679A patent/PL177811B1/en unknown
- 1993-07-08 JP JP16911493A patent/JP3311431B2/en not_active Expired - Lifetime
- 1993-07-09 MX MX9304133A patent/MX9304133A/en active IP Right Grant
- 1993-07-09 AU AU41864/93A patent/AU664101B2/en not_active Expired
- 1993-07-09 ZA ZA934971A patent/ZA934971B/en unknown
- 1993-07-09 CA CA002511753A patent/CA2511753C/en not_active Expired - Lifetime
- 1993-07-09 CA CA002100228A patent/CA2100228C/en not_active Expired - Lifetime
- 1993-07-09 HU HU9301992A patent/HU218783B/en unknown
- 1993-07-09 RU RU93047049A patent/RU2108336C1/en active
- 1993-07-09 HR HR931046A patent/HRP931046B1/en not_active IP Right Cessation
- 1993-07-09 BR BR9302809A patent/BR9302809A/en not_active Application Discontinuation
- 1993-07-09 SI SI9300365A patent/SI9300365B/en unknown
- 1993-07-09 IL IL10628993A patent/IL106289A/en not_active IP Right Cessation
- 1993-07-09 UA UA93002052A patent/UA40567C2/en unknown
- 1993-07-09 FI FI933165A patent/FI111262B/en not_active IP Right Cessation
- 1993-07-10 CN CN93108564A patent/CN1039012C/en not_active Expired - Lifetime
- 1993-07-10 KR KR1019930012980A patent/KR100297180B1/en not_active Expired - Lifetime
- 1993-07-12 LV LVP-93-988A patent/LV10870B/en unknown
1994
- 1994-10-25 EE EE9400199A patent/EE03140B1/en unknown
1999
- 1999-03-08 GR GR990400689T patent/GR3029602T3/en unknown

Also Published As

Publication number	Publication date
ATE176477T1 (en)	1999-02-15
MX9304133A (en)	1994-04-29
EP0579939B1 (en)	1999-02-03
LT3113B (en)	1994-12-27
GR3029602T3 (en)	1999-06-30
JPH0733791A (en)	1995-02-03
SI9300365A (en)	1994-03-31
CN1084175A (en)	1994-03-23
EE03140B1 (en)	1998-12-15
ES2129053T3 (en)	1999-06-01
YU49079B (en)	2003-08-29
HU218783B (en)	2000-12-28
KR940002265A (en)	1994-02-17
PL177811B1 (en)	2000-01-31
NO932502L (en)	1994-01-12
HU9301992D0 (en)	1993-09-28
PL299624A1 (en)	1994-02-21
EP0579939A1 (en)	1994-01-26
CN1039012C (en)	1998-07-08
HRP931046A2 (en)	1997-04-30
CA2100228C (en)	2006-01-24
LTIP620A (en)	1994-07-15
HUT64548A (en)	1994-01-28
LV10870A (en)	1995-10-20
SI9300365B (en)	2002-02-28
DK0579939T3 (en)	1999-09-20
LV10870B (en)	1996-06-20
PL173388B1 (en)	1998-02-27
KR100297180B1 (en)	2001-11-30
NO306468B1 (en)	1999-11-08
IL106289A0 (en)	1994-04-12
AU664101B2 (en)	1995-11-02
BR9302809A (en)	1994-03-15
FI933165A0 (en)	1993-07-09
UA40567C2 (en)	2001-08-15
CA2100228A1 (en)	1994-01-12
RU2108336C1 (en)	1998-04-10
IL106289A (en)	2000-06-01
TW304956B (en)	1997-05-11
AU4186493A (en)	1994-01-13
CA2511753A1 (en)	1994-01-12
FI111262B (en)	2003-06-30
DE59309355D1 (en)	1999-03-18
YU47393A (en)	1997-08-22
ZA934971B (en)	1994-02-01
SG46249A1 (en)	1998-02-20
HRP931046B1 (en)	2000-06-30
DE4222910A1 (en)	1994-01-13
NO932502D0 (en)	1993-07-08
CZ124993A3 (en)	1995-03-15
PL175607B1 (en)	1999-01-29
CA2511753C (en)	2007-09-25
SK67093A3 (en)	1995-03-08
CZ290863B6 (en)	2002-11-13
SK283827B6 (en)	2004-02-03
JP3311431B2 (en)	2002-08-05

Publication	Publication Date	Title
FI942645A0 (en)	1994-06-03	New peptide derivatives
FI934332L (en)	1993-10-01	NEW PROTEASTER
FI923515L (en)	1993-02-06	NEW HERBICIDER
FI925549L (en)	1993-06-10	New azaheterocyclylmethyl-chromaner
FI923264L (en)	1993-01-18	NEW HERBICIDER
FI923575A7 (en)	1993-02-13	FOERFARANDE FOER FRAMSTAELLNING AV NYA 1-ACYLPIPERIDINFOERENINGAR
FI924453L (en)	1993-04-05	NYA 9-AMINO-7-(SUBSTITUERAD)-6-DEMETHYL-6-DEOXITETRACYCLINER
FI924557A0 (en)	1992-10-08	NYA PHENYLPYRAZOLFUNGICIDER
FI934575A7 (en)	1993-10-15	NYA CENTRALT VERKANDE SUBSTITUERADE FENYLAZACYCLOALKANER
FI933451A0 (en)	1993-08-03	NYA STEROIDESTRAR
FI933450A0 (en)	1993-08-03	NYA STEROIDER
FI933285L (en)	1994-01-23	NEW HERBICIDER
FI925086A0 (en)	1992-11-09	NYA HYBRID-VAEXTFAKTORER
FI921614A7 (en)	1992-10-12	NEW HERBICIDER
FI932028L (en)	1993-11-09	FOERFARANDE FOER FRAMSTAELLNING AV NYA N-ARALKYL- OCH N-HETERORALKYLAMINOALKANFOSFINSYROR
FI960367A0 (en)	1996-01-26	New dialkoxypyridinylbenzimidazole derivatives
FI932640L (en)	1993-12-12	NYA RODIUMINNEHAOLLANDE SELECTIVA KATALYTER FOER EN SYNTES AV EPOXISILOXAN/EPOXISILICON MONOMERER OCH -POLYMERER
FI930495A7 (en)	1993-09-13	NEW HERBICIDER
FI931585L (en)	1993-10-09	NEW FUNGICIDA TRIAZOL- OCH IMIDAZOLDERIVAT
FI934331L (en)	1993-10-01	NEW PROTEASTER
FI934333L (en)	1993-10-01	NEW PROTEASTER
FI933165A7 (en)	1994-01-12	NEW PHOSPHOLIC PYDRIDE DERIVATIVES
FI932511A7 (en)	1993-12-04	NEW THIOSEMICARBAZONE DERIVATIVES
FI930139A7 (en)	1993-07-15	NEW HERBICIDER
FI932691L (en)	1993-12-13	NEW BENZYL- OCH BENZHYDRYLALCHOLER

Legal Events

Date	Code	Title	Description
2010-09-02	PC	Transfer of assignment of patent	Owner name: AETERNA ZENTARIS GMBH Free format text: AETERNA ZENTARIS GMBH
2013-08-16	MA	Patent expired

Date

Code

Title

Description

2010-09-02

Transfer of assignment of patent

Owner name: AETERNA ZENTARIS GMBH

Free format text: AETERNA ZENTARIS GMBH

2013-08-16

Patent expired