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FI932659L - Gallsyraderivat, foerfaranden foer deras framstaellning och anvaendning avdessa foereningar som laekemedel - Google Patents

Gallsyraderivat, foerfaranden foer deras framstaellning och anvaendning avdessa foereningar som laekemedel Download PDF

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Publication number
FI932659L
FI932659L FI932659A FI932659A FI932659L FI 932659 L FI932659 L FI 932659L FI 932659 A FI932659 A FI 932659A FI 932659 A FI932659 A FI 932659A FI 932659 L FI932659 L FI 932659L
Authority
FI
Finland
Prior art keywords
gallsyraderivat
avdessa
foereningar
deras framstaellning
framstaellning och
Prior art date
Application number
FI932659A
Other languages
English (en)
Other versions
FI932659A0 (fi
FI106801B (fi
Inventor
Alfons Enhsen
Heiner Glombik
Werner Kramer
Guenther Wess
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI932659A0 publication Critical patent/FI932659A0/fi
Publication of FI932659L publication Critical patent/FI932659L/fi
Application granted granted Critical
Publication of FI106801B publication Critical patent/FI106801B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Train Traffic Observation, Control, And Security (AREA)
  • Motorcycle And Bicycle Frame (AREA)
FI932659A 1992-06-12 1993-06-10 Menetelmä terapeuttisesti käyttökelpoisten sappihappojohdannaisten valmistamiseksi FI106801B (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4219274 1992-06-12
DE4219274 1992-06-12

Publications (3)

Publication Number Publication Date
FI932659A0 FI932659A0 (fi) 1993-06-10
FI932659L true FI932659L (fi) 1993-12-13
FI106801B FI106801B (fi) 2001-04-12

Family

ID=6460884

Family Applications (1)

Application Number Title Priority Date Filing Date
FI932659A FI106801B (fi) 1992-06-12 1993-06-10 Menetelmä terapeuttisesti käyttökelpoisten sappihappojohdannaisten valmistamiseksi

Country Status (21)

Country Link
US (1) US5428182A (fi)
EP (1) EP0573848B1 (fi)
JP (1) JP3403218B2 (fi)
KR (1) KR100319562B1 (fi)
AT (1) ATE160783T1 (fi)
AU (1) AU663592B2 (fi)
CA (1) CA2098256C (fi)
CY (1) CY2117B1 (fi)
CZ (1) CZ285104B6 (fi)
DE (1) DE59307759D1 (fi)
DK (1) DK0573848T3 (fi)
ES (1) ES2111092T3 (fi)
FI (1) FI106801B (fi)
GR (1) GR3025799T3 (fi)
HU (1) HU216636B (fi)
IL (1) IL105980A (fi)
NO (1) NO304653B1 (fi)
NZ (1) NZ247827A (fi)
SK (1) SK280819B6 (fi)
TW (1) TW228004B (fi)
ZA (1) ZA934150B (fi)

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CA2815749C (en) 2010-11-04 2019-12-03 Albireo Ab Ibat inhibitors for the treatment of liver diseases
SG190433A1 (en) 2010-11-08 2013-06-28 Albireo Ab A pharmaceutical combination comprising an ibat inhibitor and a bile acid binder
PT2771003T (pt) 2011-10-28 2017-07-26 Lumena Pharmaceuticals Llc Inibidores da reciclagem de ácidos biliares para tratamento de doenças hepáticas colestáticas pediátricas
EP2770990A4 (en) 2011-10-28 2015-03-11 Lumena Pharmaceuticals Inc Gallic acid refluxing agent for the treatment of hypertension and chronic liver disease
AU2014228850A1 (en) 2013-03-15 2015-10-29 Lumena Pharmaceuticals Llc Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease
MX2015013196A (es) 2013-03-15 2016-04-15 Lumena Pharmaceuticals Inc Inhibidores de reciclaje de acidos biliares para el tratamiento de la enfermedad de reflujo gastroesofagico y esofago de barrett.
JO3301B1 (ar) 2013-04-26 2018-09-16 Albireo Ab تعديلات بلورية على إيلوبيكسيبات
JP6751020B2 (ja) 2014-06-25 2020-09-02 Ｅａファーマ株式会社 固形製剤及びその着色防止又は着色低減方法
EP3012252A1 (en) 2014-10-24 2016-04-27 Ferring BV Crystal modifications of elobixibat
EP3413878B1 (en) 2016-02-09 2021-04-14 Albireo AB Oral cholestyramine formulation and use thereof
JP6954926B2 (ja) 2016-02-09 2021-10-27 アルビレオ・アクチボラグ 経口コレスチラミン製剤及びその使用
US10786529B2 (en) 2016-02-09 2020-09-29 Albireo Ab Oral cholestyramine formulation and use thereof
US10441605B2 (en) 2016-02-09 2019-10-15 Albireo Ab Oral cholestyramine formulation and use thereof
US10441604B2 (en) 2016-02-09 2019-10-15 Albireo Ab Cholestyramine pellets and methods for preparation thereof
WO2019032027A1 (en) 2017-08-09 2019-02-14 Albireo Ab CHOLESTYRAMINE TABLETS, ORAL FORMULATIONS OF CHOLESTYRAMINE AND THEIR USE
CA3071285A1 (en) 2017-08-09 2019-02-14 Albireo Ab Cholestyramine granules, oral cholestyramine formulations and use thereof
TW202015699A (zh) 2018-06-05 2020-05-01 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽汁酸調節劑之用途
US10793534B2 (en) 2018-06-05 2020-10-06 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
WO2019245448A1 (en) 2018-06-20 2019-12-26 Albireo Ab Crystal modifications of odevixibat
US11801226B2 (en) 2018-06-20 2023-10-31 Albireo Ab Pharmaceutical formulation of odevixibat
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof
US11549878B2 (en) 2018-08-09 2023-01-10 Albireo Ab In vitro method for determining the adsorbing capacity of an insoluble adsorbant
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CN118834175A (zh) 2019-02-06 2024-10-25 阿尔比里奥公司 苯并硫氮杂环庚三烯化合物及其用作胆汁酸调节剂的用途
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TWI877263B (zh) 2019-12-04 2025-03-21 瑞典商艾爾比瑞歐公司 苯并噻二氮呯化合物及其作為膽酸調節劑之用途
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TW202313579A (zh) 2021-06-03 2023-04-01 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途
CN119343140A (zh) 2022-06-09 2025-01-21 阿尔比里奥公司 治疗肝炎
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US20240207286A1 (en) 2022-12-09 2024-06-27 Albireo Ab Asbt inhibitors in the treatment of renal diseases
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Also Published As

Publication number Publication date
KR100319562B1 (ko) 2002-05-13
AU663592B2 (en) 1995-10-12
AU4018093A (en) 1993-12-16
US5428182A (en) 1995-06-27
EP0573848A3 (de) 1995-06-07
NO932159D0 (no) 1993-06-11
CZ113493A3 (en) 1994-01-19
KR940005652A (ko) 1994-03-22
NO932159L (no) 1993-12-13
CY2117B1 (en) 2002-04-26
JPH0687884A (ja) 1994-03-29
EP0573848B1 (de) 1997-12-03
SK58593A3 (en) 1994-03-09
JP3403218B2 (ja) 2003-05-06
ZA934150B (en) 1994-01-13
FI932659A0 (fi) 1993-06-10
IL105980A0 (en) 1993-10-20
TW228004B (fi) 1994-08-11
CA2098256A1 (en) 1993-12-13
HU216636B (hu) 1999-07-28
EP0573848A2 (de) 1993-12-15
CA2098256C (en) 2004-08-24
FI106801B (fi) 2001-04-12
ES2111092T3 (es) 1998-03-01
ATE160783T1 (de) 1997-12-15
HUT64772A (en) 1994-02-28
CZ285104B6 (cs) 1999-05-12
NZ247827A (en) 1995-08-28
DK0573848T3 (da) 1998-08-10
HU9301716D0 (en) 1993-09-28
GR3025799T3 (en) 1998-03-31
DE59307759D1 (de) 1998-01-15
IL105980A (en) 1997-11-20
SK280819B6 (sk) 2000-08-14
NO304653B1 (no) 1999-01-25

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