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FI935063L - Crystalline carbapenem derivative - Google Patents

Crystalline carbapenem derivative Download PDF

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Publication number
FI935063L
FI935063L FI935063A FI935063A FI935063L FI 935063 L FI935063 L FI 935063L FI 935063 A FI935063 A FI 935063A FI 935063 A FI935063 A FI 935063A FI 935063 L FI935063 L FI 935063L
Authority
FI
Finland
Prior art keywords
carbapenem derivative
crystalline carbapenem
crystalline
derivative
carbapenem
Prior art date
Application number
FI935063A
Other languages
Finnish (fi)
Other versions
FI935063A0 (en
FI103576B (en
FI103576B1 (en
Inventor
Isao Kawamoto
Masao Miyauchi
Rokuro Endo
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of FI935063A0 publication Critical patent/FI935063A0/en
Publication of FI935063L publication Critical patent/FI935063L/en
Application granted granted Critical
Publication of FI103576B publication Critical patent/FI103576B/en
Publication of FI103576B1 publication Critical patent/FI103576B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
FI935063A 1992-11-17 1993-11-16 Process for the preparation of a crystalline carbapenem derivative useful as a medicament FI103576B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP30688492 1992-11-17
JP30688492 1992-11-17
JP17026793 1993-07-09
JP17026793 1993-07-09

Publications (4)

Publication Number Publication Date
FI935063A0 FI935063A0 (en) 1993-11-16
FI935063L true FI935063L (en) 1994-05-18
FI103576B FI103576B (en) 1999-07-30
FI103576B1 FI103576B1 (en) 1999-07-30

Family

ID=26493307

Family Applications (1)

Application Number Title Priority Date Filing Date
FI935063A FI103576B1 (en) 1992-11-17 1993-11-16 Process for the preparation of a crystalline carbapenem derivative useful as a medicament

Country Status (20)

Country Link
US (1) US5424306A (en)
EP (1) EP0599512B1 (en)
JP (1) JP2848552B2 (en)
KR (1) KR100236845B1 (en)
CN (1) CN1036714C (en)
AT (1) ATE178066T1 (en)
AU (1) AU677235B2 (en)
CA (1) CA2103223C (en)
CZ (1) CZ280507B6 (en)
DE (1) DE69324106T2 (en)
DK (1) DK0599512T3 (en)
ES (1) ES2131560T3 (en)
FI (1) FI103576B1 (en)
GR (1) GR3029975T3 (en)
HU (1) HU219582B (en)
IL (1) IL107596A (en)
NO (1) NO304431B1 (en)
NZ (1) NZ250201A (en)
PH (1) PH30464A (en)
TW (1) TW360657B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2253860A1 (en) * 1996-05-09 1997-11-13 Sankyo Company, Limited Anti-helicobacter pylori compositions containing 1-methylcarbapenem derivatives as the active ingredient
TWI250160B (en) 1999-07-06 2006-03-01 Sankyo Co Crystalline 1-methylcarbapenem compound
US7041660B2 (en) * 1999-07-06 2006-05-09 Sankyo Company, Limited Crystalline 1-methylcarbapenem derivatives
KR100451672B1 (en) * 2001-06-05 2004-10-08 한미약품 주식회사 Crystalline acid salts of cefdinir, process for their preparation and process for the preparation of cefdinir using same
ITMI20012364A1 (en) * 2001-11-09 2003-05-09 Antibioticos Spa SUMMARY PROCESS OF CEFIXIMA VIA ALCHIL-O ARILSOLFONATI
CA2477088A1 (en) 2002-02-22 2003-10-02 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
WO2004035539A1 (en) * 2002-10-18 2004-04-29 Meiji Seika Kaisha, Ltd. Process for producing carbapenem derivative and intermediate for use in the production
EP1776365B1 (en) * 2004-06-02 2011-08-03 Sandoz Ag Meropenem intermediate in crystalline form
JP2009143808A (en) * 2006-03-28 2009-07-02 Kaneka Corp Method for isolating meropenem intermediate
PL2121578T3 (en) 2007-01-12 2017-02-28 Novartis Ag Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242914A (en) * 1988-04-01 1993-09-07 Sankyo Company, Limited 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics
DK175029B1 (en) * 1988-04-01 2004-05-03 Sankyo Co 2- (heterocyclylthio) carbapenem derivatives, pharmaceutical agents containing them, process for their preparation, and their use as antibiotics
JPH0745499B2 (en) * 1988-05-10 1995-05-17 三共株式会社 1-methylcarbapenem derivative
EP0462521A1 (en) * 1990-06-19 1991-12-27 Takeda Chemical Industries, Ltd. Crystalline penem, its production and use

Also Published As

Publication number Publication date
JPH07165759A (en) 1995-06-27
DE69324106D1 (en) 1999-04-29
AU677235B2 (en) 1997-04-17
DK0599512T3 (en) 1999-10-11
HK1011977A1 (en) 1999-07-23
IL107596A (en) 1998-02-08
EP0599512B1 (en) 1999-03-24
JP2848552B2 (en) 1999-01-20
US5424306A (en) 1995-06-13
KR940011463A (en) 1994-06-21
CN1093366A (en) 1994-10-12
FI935063A0 (en) 1993-11-16
PH30464A (en) 1997-05-28
ES2131560T3 (en) 1999-08-01
HUT66001A (en) 1994-08-29
AU5063193A (en) 1994-06-02
KR100236845B1 (en) 2000-02-01
TW360657B (en) 1999-06-11
ATE178066T1 (en) 1999-04-15
CA2103223A1 (en) 1994-05-18
HU219582B (en) 2001-05-28
CZ280507B6 (en) 1996-02-14
NZ250201A (en) 1995-04-27
NO934140D0 (en) 1993-11-16
CN1036714C (en) 1997-12-17
FI103576B (en) 1999-07-30
IL107596A0 (en) 1994-02-27
CA2103223C (en) 2002-09-24
FI103576B1 (en) 1999-07-30
NO304431B1 (en) 1998-12-14
NO934140L (en) 1994-05-18
EP0599512A1 (en) 1994-06-01
GR3029975T3 (en) 1999-07-30
DE69324106T2 (en) 1999-12-09
CZ245493A3 (en) 1995-08-16

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MA Patent expired