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FI934710L - 4-ARYL-3-(HETEROARYLUREIDO)QUINOLINE DERIVATIVES - Google Patents

4-ARYL-3-(HETEROARYLUREIDO)QUINOLINE DERIVATIVES Download PDF

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Publication number
FI934710L
FI934710L FI934710A FI934710A FI934710L FI 934710 L FI934710 L FI 934710L FI 934710 A FI934710 A FI 934710A FI 934710 A FI934710 A FI 934710A FI 934710 L FI934710 L FI 934710L
Authority
FI
Finland
Prior art keywords
heteroarylureido
aryl
quinoline derivatives
quinoline
derivatives
Prior art date
Application number
FI934710A
Other languages
Finnish (fi)
Other versions
FI934710A0 (en
FI934710A7 (en
Inventor
Ernest S Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI934710A0 publication Critical patent/FI934710A0/en
Publication of FI934710A7 publication Critical patent/FI934710A7/en
Publication of FI934710L publication Critical patent/FI934710L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
FI934710A 1991-04-26 1992-03-16 4-ARYL-3-(HETEROARYLUREIDO)QUINOLINE DERIVATIVES FI934710L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69232391A 1991-04-26 1991-04-26
PCT/US1992/001801 WO1992019614A1 (en) 1991-04-26 1992-03-16 4-aryl-3-(heteroarylureido)quinoline derivatives

Publications (3)

Publication Number Publication Date
FI934710A0 FI934710A0 (en) 1993-10-25
FI934710A7 FI934710A7 (en) 1993-10-25
FI934710L true FI934710L (en) 1993-10-25

Family

ID=24780107

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934710A FI934710L (en) 1991-04-26 1992-03-16 4-ARYL-3-(HETEROARYLUREIDO)QUINOLINE DERIVATIVES

Country Status (20)

Country Link
EP (1) EP0590094A1 (en)
JP (1) JPH0776215B2 (en)
CN (1) CN1066068A (en)
AU (1) AU1879792A (en)
BR (1) BR9205939A (en)
CA (1) CA2108014A1 (en)
CZ (1) CZ395592A3 (en)
DE (1) DE9290049U1 (en)
FI (1) FI934710L (en)
HU (1) HUT65748A (en)
IE (1) IE921330A1 (en)
IL (1) IL101627A0 (en)
MX (1) MX9201916A (en)
NO (1) NO933837L (en)
NZ (1) NZ242493A (en)
PT (1) PT100426A (en)
TW (1) TW197436B (en)
WO (1) WO1992019614A1 (en)
YU (1) YU44592A (en)
ZA (1) ZA922976B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2668163B2 (en) * 1992-01-23 1997-10-27 ファイザー インク. 4-Aryl-3- (heteroarylureido) -1,2-dihydro-2-oxo-quinoline derivatives as cholesterolemia and anti-atherosclerosis drugs
US5565472A (en) * 1992-12-21 1996-10-15 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
NZ264063A (en) * 1993-08-13 1995-11-27 Nihon Nohyaku Co Ltd N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
US5843957A (en) * 1995-05-19 1998-12-01 Sumitomo Pharmaceuticals Company, Ltd. Naphthyridine derivatives
ATE272635T1 (en) * 1995-05-31 2004-08-15 Sumitomo Pharma NEW NAPHTHYRIDINE DERIVATIVES.
KR20000057268A (en) * 1996-11-26 2000-09-15 다께우찌 마사야쓰 Novel naphthyridine derivatives
US6300500B1 (en) 1998-02-25 2001-10-09 Sumitomo Pharmaceuticals Company, Limited Preparation of pyridone derivatives using phthalimido containing starting material
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
CA2547518A1 (en) * 2003-12-12 2005-06-30 Wyeth Quinolines useful in treating cardiovascular disease
CN103601677B (en) * 2013-11-19 2015-11-18 清华大学 Prepare the method for 2-alkylthio quinoline

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
MX22406A (en) * 1989-09-15 1994-01-31 Pfizer NEW DERIVATIVES OF N-ARIL AND N-HETEROARILAMIDAS AND UREA AS INHIBITORS OF ACIL COENZYME A: ACIL TRANSFERASA DEL COLESTEROL (ACAT).
TW205037B (en) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
EP0590094A1 (en) 1994-04-06
TW197436B (en) 1993-01-01
MX9201916A (en) 1992-11-01
CZ395592A3 (en) 1994-02-16
WO1992019614A1 (en) 1992-11-12
FI934710A0 (en) 1993-10-25
YU44592A (en) 1994-12-28
PT100426A (en) 1993-08-31
HU9303025D0 (en) 1994-01-28
IL101627A0 (en) 1992-12-30
BR9205939A (en) 1994-09-27
NO933837L (en) 1993-10-25
NZ242493A (en) 1994-08-26
FI934710A7 (en) 1993-10-25
ZA922976B (en) 1993-10-25
DE9290049U1 (en) 1994-01-05
HUT65748A (en) 1994-07-28
JPH0776215B2 (en) 1995-08-16
IE921330A1 (en) 1992-11-04
AU1879792A (en) 1992-12-21
CN1066068A (en) 1992-11-11
CA2108014A1 (en) 1992-10-27
JPH06501025A (en) 1994-01-27

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